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Preimplantation Genetic Testing An Overview
Preimplantation Genetic Testing An Overview

... Interpretation of results.  Ratio of the fluorescence intensities is proportional to the ratio of 'copy number of DNA sequences' in the test and reference genomes.  Altered Cy 3 : Cy 5 ratio indicates a loss or gain of the patient DNA at that specific genomic region  If Cy 3 : Cy 5 ratio is equal ...
DNA sequencing - Rarechromo.org
DNA sequencing - Rarechromo.org

... DNA sequence and there are lots of tiny genetic (DNA) differences between all of us, some common and some rare. This makes finding the genetic differences that cause a particular developmental disorder especially challenging. These DNA changes are known as copy number variants (CNVs) or single nucle ...
DNA sequencing - Rarechromo.org
DNA sequencing - Rarechromo.org

... Every chromosome contains thousands of genes which may be thought of as individual instruction booklets (or recipes) that contain all the genetic information telling the body how to develop, grow and function. The human genome contains around 20,000 genes. A gene is a functional region of DNA that p ...
Reebops: A "Model" Organism for Teaching Genetic Concepts
Reebops: A "Model" Organism for Teaching Genetic Concepts

... DNA strand is an extremely long molecule. When cells are not dividing (splitting into two new cells), the DNA will be uncoiled and spread over the entire cell nucleus. But when a cell is preparing to divide, each long DNA strand will coil tightly to form a chromosome. When this happens, the chromoso ...
File - jj-sct
File - jj-sct

...  In humans and other mammals, there are two varieties of sex chromosomes: a larger X chromosome and a smaller Y chromosome  A person with two X chromosomes develops as a female, while a male develops from a zygote with one X and one Y  Only the ends of the Y chromosome have regions that are homol ...
The Big Picture: an outline of the concepts covered to date
The Big Picture: an outline of the concepts covered to date

... A. Each diploid individual contains two copies of a given gene B. Each Gene can have different forms called alleles. There are two alleles in a diploid individual The form that is expressed phenotypically in the heterozygote is known as the dominant allele. It is an operational definition C. These c ...
22q12 and 22q13 duplications
22q12 and 22q13 duplications

... microduplications have been described recently in a number of people. However, pure duplications of 22q12/13 are have been rarely detected and only around 25 people have been reported in the published medical literature. Deletions of the same region of 22q13 have been reported much more frequently a ...
Meiosis
Meiosis

... haploid multicellular stage – The diploid organism, called the sporophyte(孢子體), makes haploid spores(孢 子) by meiosis – Each spore grows by mitosis into a haploid organism called a gametophyte (配子體) – A gametophyte makes haploid gametes by ...
08_Lecture_Presentation
08_Lecture_Presentation

... – Occurs in prokaryotic cells – Two identical cells arise from one cell – Steps in the process – A single circular chromosome duplicates, and the copies begin to separate from each other – The cell elongates, and the chromosomal copies separate ...
Meiosis I
Meiosis I

... genetic balance less than an unusual number of autosomes. This may be because of • the small size of the Y chromosome or • X chromosome inactivation. ...
ch 8 notes
ch 8 notes

...  Somatic cells have pairs of homologous chromosomes, receiving one member of each pair from each parent  Homologous chromosomes are matched in – Length – Centromere position – Gene locations – A locus (plural, loci) is the position of a gene – Different versions of a gene may be found at the same ...
PowerPoint
PowerPoint

... Ex: what would you get if you crossed a Brown-haired brown-eyed male with a blondehaired blue-eyed female? How many of the children would have brown hair and brown eyes? Brown hair and blue eyes? Blonde hair and brown eyes? Blonde hair and blue eyes? ...
II. Purpose of Meiosis #1
II. Purpose of Meiosis #1

... This outline is the same as is found in your Lecture Guide. In order to obtain an overview of the material in the Lecture Guide and to be able to see the ‘big’ picture while you study, fill in the missing components of the following outline from the Lecture Guide. ...
F 1
F 1

... Concept 8.1 Genes Are Particulate and Are Inherited According to ...
Genetic Inheritance - leavingcertbiology.net
Genetic Inheritance - leavingcertbiology.net

... • Sex-linked genes can also be said to be X-linked • The X chromosome carries many more genes (~800 more genes) than the Y chromosome • Recessive genotypes for particular traits that are Xlinked therefore occur more frequently in males than in females • Females have a pair of genes governing each tr ...
Unit 2
Unit 2

... 5. What fraction of your mother's children was male? 6. Now, get the number of male children and the total number of children for the mothers of each of your classmates, and calculate the overall fraction male offspring. 7. Compare the predicted fraction male with the observed fraction male for you ...
Brooker Chapter 3
Brooker Chapter 3

... – Mitosis produces two diploid daughter cells – Meiosis produces four haploid daughter cells – Mitosis produces daughter cells that are genetically identical – Meiosis produces daughter cells that are not genetically identical • The daughter cells contain only one homologous chromosome from each pai ...
Vital Genes in the Heterochromatin of
Vital Genes in the Heterochromatin of

... degenerate transposons. Moreover, about one hundred predicted genes that escaped previous genetic analyses have been associated with the proximal regions of chromosome arms but it remains to be determined how many of these genes are actually located within the heterochromatin. In this overview, we p ...
Identification of a 5S rDNA spacer type specific to Triticum urartu and
Identification of a 5S rDNA spacer type specific to Triticum urartu and

... particularly between closely related species such as those of the Triticeae. In Triticeae, two principal lineages of 5S rDNA have been identified, 5S-DNA-1 and 5S-DNA-2, most readily defined by the lengths and sequence compositions of their spacers (Gerlach and Dyer 1980; Dvorák et al.1989; Appels e ...
W W W W W W W W W W W W W W W
W W W W W W W W W W W W W W W

... the father an albino. The first two questions on page 5 of the Student Handout require students to use their understanding of inheritance and Punnett squares to interpret the results of the simulation. The alleles for the parents in this simulation have been chosen to ensure that at least one trait ...
Are all sex chromosomes created equal?
Are all sex chromosomes created equal?

... do homogametic sex chromosomes (Z and X) evolve? We use these to explore a diverse range of evolutionary issues including the relative importance of adaptation and degenerative processes, the implications of genomic conflict, and the consequences of sexual selection. Box 2. Degeneration of non-recom ...
Dragon Genetics - Sherrilyn Kenyon
Dragon Genetics - Sherrilyn Kenyon

... Will any of the fire-breathing baby dragons have short fangs? Will any of the fire-breathing baby dragons have no wings? Explain how genetic linkage accounts for these results. 6. Based on your drawings in the above chart and the Punnett square on the previous page, answer the following two question ...
meiosis
meiosis

...  Somatic cells have pairs of homologous chromosomes, receiving one member of each pair from each parent  Homologous chromosomes are matched in – Length – Centromere position – Gene locations – A locus (plural, loci) is the position of a gene – Different versions of a gene may be found at the same ...
Angelman Syndrome - Continuum of Care
Angelman Syndrome - Continuum of Care

... gait, absent speech, seizures, and excessive laughter. Initially it was presumed to be rare, but now it is believed that thousands of cases have gone undiagnosed, or misdiagnosed as cerebral palsy, autism, or other childhood disorders. The incidence is not known, but is estimated at 1in 15,000 to 1 ...
Introduction – Chapter 8 Introduction 8.1 Cell division plays many
Introduction – Chapter 8 Introduction 8.1 Cell division plays many

... – sorts new sets of chromosomes into the resulting pair of daughter cells.  Cell division is used – for reproduction of single-celled organisms, – growth of multicellular organisms from a fertilized egg into an adult, – repair and replacement of cells, and – sperm and egg production. © 2012 Pearson ...
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Y chromosome



The Y chromosome is one of two sex chromosomes (allosomes) in mammals, including humans, and many other animals. The other is the X chromosome. Y is the sex-determining chromosome in many species, since it is the presence or absence of Y that determines the male or female sex of offspring produced in sexual reproduction. In mammals, the Y chromosome contains the gene SRY, which triggers testis development. The DNA in the human Y chromosome is composed of about 59 million base pairs. The Y chromosome is passed only from father to son. With a 30% difference between humans and chimpanzees, the Y chromosome is one of the fastest evolving parts of the human genome. To date, over 200 Y-linked genes have been identified. All Y-linked genes are expressed and (apart from duplicated genes) hemizygous (present on only one chromosome) except in the cases of aneuploidy such as XYY syndrome or XXYY syndrome. (See Y linkage.)
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