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... Shape Representation • Graph representation of Cryo-EM volume via skeletons – 3D Skeleton [Ju 06] builds connectivity among detected helices – An edge: a detected helix or a skeleton path between two helices • Attribute: length of the helix or skeleton path ...
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15.1 The Genetic Code
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2/17/12 Gene regulation
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Gene Normalization - Computational Bioscience Program

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IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.

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... between specific PKs and particular sites is crucial to elucidate related biological pathways. On a more technical level, highthroughput assays are needed to establish these valid kinase-client interactions. Past methods have used low-throughput methods such as radiolabeling or 2D-gel electrophoresi ...
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...  Only a single plasmid construction is required  Interactions are detected in vivo  Weak, transient interactions can be detected  Can accumulate a weak signal over time ...
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Biochemistry Test Review

... 45. What are some lipids that are not triglycerides? What are their roles in living things? 46. Compare the properties of saturated and unsaturated fats. 47. What are nucleic acids and of what monomers are they made? 48. What are the three subunits of a single monomer in a nucleic acid? 49. Why is t ...
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Intrinsically disordered proteins



An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure. IDPs cover a spectrum of states from fully unstructured to partially structured and include random coils, (pre-)molten globules, and large multi-domain proteins connected by flexible linkers. They constitute one of the main types of protein (alongside globular, fibrous and membrane proteins).The discovery of IDPs has challenged the traditional protein structure paradigm, that protein function depends on a fixed three-dimensional structure. This dogma has been challenged over the last decades by increasing evidence from various branches of structural biology, suggesting that protein dynamics may be highly relevant for such systems. Despite their lack of stable structure, IDPs are a very large and functionally important class of proteins. In some cases, IDPs can adopt a fixed three-dimensional structure after binding to other macromolecules.
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