PyMOL Modelling Workshop Outline of PyMOL usage
... When assessing a structure, one needs to take account of the resolution and R-factor, error estimates and missing residues. There is information about the sequence that was used to determine the structure with a sequence database reference. There is also information about the biological unit. In the ...
... When assessing a structure, one needs to take account of the resolution and R-factor, error estimates and missing residues. There is information about the sequence that was used to determine the structure with a sequence database reference. There is also information about the biological unit. In the ...
Aspects of Reductive Explanation in Biological Science: Intrinsicality
... Structure of Science ([1961]). Schaffner argued that reduction was occurring in biology, especially in the molecularization of genetics ([1969]), but that this philosophical interpretation was not relevant to ongoing research methodology ([1974]). The ensuing discussion about the relationship betwee ...
... Structure of Science ([1961]). Schaffner argued that reduction was occurring in biology, especially in the molecularization of genetics ([1969]), but that this philosophical interpretation was not relevant to ongoing research methodology ([1974]). The ensuing discussion about the relationship betwee ...
Protein 3D-structure analysis
... http://www.rcsb.org/pdb/explore/explore.do?structureId=1THC Similar structure: 2H6U What is the function of transthyretin, respectively of other proteins with similar structure? Have a look at the corresponding UniProt entries! How are they classified at CATH Use text search http://www.cathdb.info/c ...
... http://www.rcsb.org/pdb/explore/explore.do?structureId=1THC Similar structure: 2H6U What is the function of transthyretin, respectively of other proteins with similar structure? Have a look at the corresponding UniProt entries! How are they classified at CATH Use text search http://www.cathdb.info/c ...
Physical and chemical interactions between aphids and plants
... may be different for other phloem-specific proteins. In cucurbits, mRNAs encoding for the most abundant SE proteins PP1 and PP2 (both involved in sieve plate protein plugging) were only found in the CCs, not in the SEs (Bostwick et al., 1992; Clark et al., 1997; Dannenhoffer et al., 1997). Turnover ...
... may be different for other phloem-specific proteins. In cucurbits, mRNAs encoding for the most abundant SE proteins PP1 and PP2 (both involved in sieve plate protein plugging) were only found in the CCs, not in the SEs (Bostwick et al., 1992; Clark et al., 1997; Dannenhoffer et al., 1997). Turnover ...
Docking with GOLD Tutorial
... orientation of the amide groups in Asn and Gln side chains protein side chains can move ? Have I checked that: there is crystallographic evidence for the position of long and surface exposed side chains, such as Arg and Lys ? there are no unwanted water or buffer molecules in my active site ? ...
... orientation of the amide groups in Asn and Gln side chains protein side chains can move ? Have I checked that: there is crystallographic evidence for the position of long and surface exposed side chains, such as Arg and Lys ? there are no unwanted water or buffer molecules in my active site ? ...
Book of Abstracts
... atom of different species which is confined by an isotropic potential. We first apply a \pi/2 pulse to transform two components of fermions into two superposition states. Their interactions with the impurity atom then cause a "transport" of fermions from majority to minority superposition states, wh ...
... atom of different species which is confined by an isotropic potential. We first apply a \pi/2 pulse to transform two components of fermions into two superposition states. Their interactions with the impurity atom then cause a "transport" of fermions from majority to minority superposition states, wh ...
nmr.evilia.190303
... In structure work, J coupling is critical to measuring the bond angles and dihedral angles between nuclei. The Karplus equation is used to calculate the dihedral angles for 3 bond or vicinal coupling: J = A + B cosq+ C cos2q Where A, B, C are coefficients that depend on the nuclei ...
... In structure work, J coupling is critical to measuring the bond angles and dihedral angles between nuclei. The Karplus equation is used to calculate the dihedral angles for 3 bond or vicinal coupling: J = A + B cosq+ C cos2q Where A, B, C are coefficients that depend on the nuclei ...
Amino Acid Metabolism
... Functions of Amino Acid Metabolism Proteins constantly undergo breakdown and synthesis Total protein turnover in a well-fed, adult human is estimated at about 300 g/day, of which approximately 100 g is myofibrillar protein, 30 g is digestive enzymes, 20 g is small intestinal cell protein, and 15 g i ...
... Functions of Amino Acid Metabolism Proteins constantly undergo breakdown and synthesis Total protein turnover in a well-fed, adult human is estimated at about 300 g/day, of which approximately 100 g is myofibrillar protein, 30 g is digestive enzymes, 20 g is small intestinal cell protein, and 15 g i ...
Identification of Saccharomyces cerevisiae proteins that bind to
... The following individuals and institutions are hereby acknowledged and thanked for their contribution to this project. Dr Gabre Kemp, thank you for your support and sacrifice in the completion of this project. Your willingness to help and guide me along the way is greatly appreciated. Thank you for ...
... The following individuals and institutions are hereby acknowledged and thanked for their contribution to this project. Dr Gabre Kemp, thank you for your support and sacrifice in the completion of this project. Your willingness to help and guide me along the way is greatly appreciated. Thank you for ...
Document
... New studies suggest that whey may uniquely influence food intake through its effects on cholecystokinin and other pathways. While many studies have shown that protein is the most filling or satiating macronutrient, all proteins may not be equal in this regard. Two human studies conducted at the Univ ...
... New studies suggest that whey may uniquely influence food intake through its effects on cholecystokinin and other pathways. While many studies have shown that protein is the most filling or satiating macronutrient, all proteins may not be equal in this regard. Two human studies conducted at the Univ ...
4 - Merck Millipore
... This guide is a resource for scientists for the preparation and use of research essential biochemicals, such as antibiotics, buffers, detergents, dyes, stains, and substrates, which are indispensable for any life science research laboratory. You will find this guide to be a useful resource, whether ...
... This guide is a resource for scientists for the preparation and use of research essential biochemicals, such as antibiotics, buffers, detergents, dyes, stains, and substrates, which are indispensable for any life science research laboratory. You will find this guide to be a useful resource, whether ...
scf and cullin/ring h2-based
... of proteins and to switch cellular regulatory circuits from one state to another by abrupt elimination of control proteins. In eukaryotes, the bulk of the protein degradation that occurs in the cytoplasm and nucleus is carried out by the 26S proteasome. In turn, most proteins are thought to be targe ...
... of proteins and to switch cellular regulatory circuits from one state to another by abrupt elimination of control proteins. In eukaryotes, the bulk of the protein degradation that occurs in the cytoplasm and nucleus is carried out by the 26S proteasome. In turn, most proteins are thought to be targe ...
Engineering the substrate and inhibitor specificities of human
... three-dimensional structure of FVIIa–sTF (soluble TF) in complex with a cmk (chloromethyl ketone) derivative mimicking an optimal substrate based on screening of the peptide substrates. On the basis of the findings from these studies, a number of variants were generated by substituting residues with ...
... three-dimensional structure of FVIIa–sTF (soluble TF) in complex with a cmk (chloromethyl ketone) derivative mimicking an optimal substrate based on screening of the peptide substrates. On the basis of the findings from these studies, a number of variants were generated by substituting residues with ...
biochemistry - Louis Bolk Instituut
... How can we do justice to life itself when studying the life sciences? Biochemistry is the area in the life sciences which pre-eminently offers insight into the continuous and manifold changes that occur in organisms. It shows substances to be not static but ever changing, in structure as well as fun ...
... How can we do justice to life itself when studying the life sciences? Biochemistry is the area in the life sciences which pre-eminently offers insight into the continuous and manifold changes that occur in organisms. It shows substances to be not static but ever changing, in structure as well as fun ...
biochemistry - Louis Bolk Institute
... How can we do justice to life itself when studying the life sciences? Biochemistry is the area in the life sciences which pre-eminently offers insight into the continuous and manifold changes that occur in organisms. It shows substances to be not static but ever changing, in structure as well as fun ...
... How can we do justice to life itself when studying the life sciences? Biochemistry is the area in the life sciences which pre-eminently offers insight into the continuous and manifold changes that occur in organisms. It shows substances to be not static but ever changing, in structure as well as fun ...
1 Engineering Lipases with an Expanded Genetic Code - Wiley-VCH
... 30–65 ∘ C but are mostly unstable in the harsh reaction environments of industrial applications, such as high temperature, organic solvents, strong alkalinity, or acidity [5]. Therefore, more and more attention is being paid to isolating and characterizing novel lipases with high stability from cult ...
... 30–65 ∘ C but are mostly unstable in the harsh reaction environments of industrial applications, such as high temperature, organic solvents, strong alkalinity, or acidity [5]. Therefore, more and more attention is being paid to isolating and characterizing novel lipases with high stability from cult ...
LWT Food Science and Technology
... alcoholic beverages contains not only polyphenols, but also proteins and amino acids. It is common knowledge that proteins and essential amino acids of food are supplying the required building blocks for protein biosynthesis of humans (Belitz and Grosch, 1999). Now some authors suggest that these su ...
... alcoholic beverages contains not only polyphenols, but also proteins and amino acids. It is common knowledge that proteins and essential amino acids of food are supplying the required building blocks for protein biosynthesis of humans (Belitz and Grosch, 1999). Now some authors suggest that these su ...
Review Antibody flexibility observed in antigen binding and its
... used the Biacore system, which utilizes surface plasmon resonance (SPR) as a means of detection, and isothermal titration calorimetry (ITC), which can detect heat in the binding of biological interactions with high sensitivity. Both SPR biosensors and ITC have been widely used to measure biomolecula ...
... used the Biacore system, which utilizes surface plasmon resonance (SPR) as a means of detection, and isothermal titration calorimetry (ITC), which can detect heat in the binding of biological interactions with high sensitivity. Both SPR biosensors and ITC have been widely used to measure biomolecula ...
Preparing and Analyzing Expressed Sequence Tags (ESTs) Library
... during the first 72 hours of lactation [8] and the excretion is intense at the first 12–36 hours [7]. Sufficient colostrums intake of newborn lambs in the first days of their lives plays essential role in their healthy growth and reaching to ideal market weight [9]. The raisers are desired to breed ...
... during the first 72 hours of lactation [8] and the excretion is intense at the first 12–36 hours [7]. Sufficient colostrums intake of newborn lambs in the first days of their lives plays essential role in their healthy growth and reaching to ideal market weight [9]. The raisers are desired to breed ...
Protein proteinase inhibitors from avian egg whites
... for the prediction of the effect of a particular amino acid residue at a specific position in the inhibitor on the inhibitory activity) was developed by Laskowski’s group [42–44]. Residues which are sequentially quite distant from the reactive site may exert great influence on the enzyme-inhibitor r ...
... for the prediction of the effect of a particular amino acid residue at a specific position in the inhibitor on the inhibitory activity) was developed by Laskowski’s group [42–44]. Residues which are sequentially quite distant from the reactive site may exert great influence on the enzyme-inhibitor r ...
BCH 101- 5 Amino acids
... All peptides and polypeptides are polymers of α-amino acids. There are 20 α-amino acids that are relevant to the make-up of mammalian proteins (see below). Several other amino acids are found in the body free or in combined states (i.e. not associated with peptides or proteins). These non-protein as ...
... All peptides and polypeptides are polymers of α-amino acids. There are 20 α-amino acids that are relevant to the make-up of mammalian proteins (see below). Several other amino acids are found in the body free or in combined states (i.e. not associated with peptides or proteins). These non-protein as ...
paper - Lirmm
... to transparently manage frameshifts that occur inside the sequence, for example by reconstructing an alignment from pieces obtained on different reading frames. For handling frameshifts at the protein level, [20] and [21] propose the use of 5 substitution matrices for aligning amino acids encoded on ...
... to transparently manage frameshifts that occur inside the sequence, for example by reconstructing an alignment from pieces obtained on different reading frames. For handling frameshifts at the protein level, [20] and [21] propose the use of 5 substitution matrices for aligning amino acids encoded on ...
A Study of Phylogenetic Relationships and Homology of
... overall species phenotype. For example, both humans and chimpanzees have many similar anatomical characters and functions, so we might expect their proteins to be similar, regardless of whether they are genealogically related or not. However, we can compare the sequences of basic genes that are used ...
... overall species phenotype. For example, both humans and chimpanzees have many similar anatomical characters and functions, so we might expect their proteins to be similar, regardless of whether they are genealogically related or not. However, we can compare the sequences of basic genes that are used ...
Chemical Nature of the Amino Acids Table of a
... In solution it is the nature of the amino acid R-groups that dictate structure-function relationships of peptides and proteins. The hydrophobic amino acids will generally be encountered in the interior of proteins shielded from direct contact with water. Conversely, the hydrophilic amino acids are g ...
... In solution it is the nature of the amino acid R-groups that dictate structure-function relationships of peptides and proteins. The hydrophobic amino acids will generally be encountered in the interior of proteins shielded from direct contact with water. Conversely, the hydrophilic amino acids are g ...
Neonatal nutrition
... • 3.5 Kg mother wants to breast feed her infant. She is primi-gravida – Is small amount of milk in first 3ds enough – How to encourage her to continue breast feeding – Signs of successful breast feeding – For how long breast feeding to continue ...
... • 3.5 Kg mother wants to breast feed her infant. She is primi-gravida – Is small amount of milk in first 3ds enough – How to encourage her to continue breast feeding – Signs of successful breast feeding – For how long breast feeding to continue ...
Protein–protein interaction
Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.