Telomere maintenance without telomerase
... a genome-wide hyper-recombination phenotype. However, this analysis did not exclude the possibility that in a cell that lacked telomerase, unreplicated telomeres could themselves become hyper-recombinogenic, a point that will be re-addressed later in this review. Although all survivors recovered fro ...
... a genome-wide hyper-recombination phenotype. However, this analysis did not exclude the possibility that in a cell that lacked telomerase, unreplicated telomeres could themselves become hyper-recombinogenic, a point that will be re-addressed later in this review. Although all survivors recovered fro ...
A surge of late-occurring meiotic double
... interhomolog DNA links, cytologically identifiable as chiasmata (Keeney 2001, 2008). During prophase I, the recombination-mediated establishment of stable interaction between homologous chromosomes (henceforth referred to as homologs) is a progressive process. It initiates at leptonema with chromoso ...
... interhomolog DNA links, cytologically identifiable as chiasmata (Keeney 2001, 2008). During prophase I, the recombination-mediated establishment of stable interaction between homologous chromosomes (henceforth referred to as homologs) is a progressive process. It initiates at leptonema with chromoso ...
Genetics of Clubroot Resistance inBrassicaSpecies | SpringerLink
... details of CR QTLs and their number and location in specific chromosomes in each species are discussed here. Brassica rapa Genetic analysis and genetic mapping of CR genes are well studied in B. rapa. All eight possible CR genes present in B. rapa have been identified through QTL mapping by research ...
... details of CR QTLs and their number and location in specific chromosomes in each species are discussed here. Brassica rapa Genetic analysis and genetic mapping of CR genes are well studied in B. rapa. All eight possible CR genes present in B. rapa have been identified through QTL mapping by research ...
Basement membranes - Development
... indicating that the absence of collagen IV did not perturb secretion and deposition of these components. However, the staining appeared weaker when compared with littermate ...
... indicating that the absence of collagen IV did not perturb secretion and deposition of these components. However, the staining appeared weaker when compared with littermate ...
Cardiovascular proteomics
... (eg, TnI, beta-adrenergic 1 receptor) • if one turns out to be important in disease, create a drug against it Proteomics approach • provides an immense amount of information on many, many proteins ...
... (eg, TnI, beta-adrenergic 1 receptor) • if one turns out to be important in disease, create a drug against it Proteomics approach • provides an immense amount of information on many, many proteins ...
Auxin represses stomatal development in dark
... mature stomata were observed in the cotyledon epidermis of 2-dayold wild-type, axr2-1 and axr3-1 mutant seedlings; the first stomata appeared between 3 and 4 dpg and excessive stomata developed in axr2-1 and axr3-1 in the following days (Fig. 2A). Hence, stomata in aux/iaa mutants do not form premat ...
... mature stomata were observed in the cotyledon epidermis of 2-dayold wild-type, axr2-1 and axr3-1 mutant seedlings; the first stomata appeared between 3 and 4 dpg and excessive stomata developed in axr2-1 and axr3-1 in the following days (Fig. 2A). Hence, stomata in aux/iaa mutants do not form premat ...
A TaqI polymorphism in the 3 UTR of the IL-12
... phenotype. For this reason, we studied in vitro IL-12 secretion by stimulated human monocytes in relation to this polymorphism. We found that the TaqI polymorphism was associated with increased secretion of IL-12 p70 by stimulated human monocytes. Individuals homozygous for the polymorphism were hig ...
... phenotype. For this reason, we studied in vitro IL-12 secretion by stimulated human monocytes in relation to this polymorphism. We found that the TaqI polymorphism was associated with increased secretion of IL-12 p70 by stimulated human monocytes. Individuals homozygous for the polymorphism were hig ...
Exploratory data analysis for microarray data
... ❍ Unsupervised learning: gene/sample annotations. ...
... ❍ Unsupervised learning: gene/sample annotations. ...
Maneeshi Prasad
... and basal forebrain—areas vital to learning, memory, and higher thinking • BDNF is also involved in neurogenesis • BDNF binds to TrkB receptor and p75NTR receptor ...
... and basal forebrain—areas vital to learning, memory, and higher thinking • BDNF is also involved in neurogenesis • BDNF binds to TrkB receptor and p75NTR receptor ...
Consulta: subjectFacets:"Oviduct" Registros recuperados: 17 Data
... complex or hybrid N-glycans of glycoproteins, was found in media cultured with bovine oviduct epithelial cells (BOEC) obtained from non-pregnant cows during the follicular phase. Combined treatment with specific hormones increased GnT I release from BOEC. Luteinizing hormone (LH; 10 ng/ml) alone sl ...
... complex or hybrid N-glycans of glycoproteins, was found in media cultured with bovine oviduct epithelial cells (BOEC) obtained from non-pregnant cows during the follicular phase. Combined treatment with specific hormones increased GnT I release from BOEC. Luteinizing hormone (LH; 10 ng/ml) alone sl ...
Calculating the Number of Genes
... • odd numbers of ploidy are not usually maintained, – 3n, 5n, etc. • rarely found in organisms that rely on sexual propagation. ...
... • odd numbers of ploidy are not usually maintained, – 3n, 5n, etc. • rarely found in organisms that rely on sexual propagation. ...
Rather than test an unmapped gene successively for linkage to... groups, it is advantageous to test all linkage groups in... alcoy David Perkins
... temperature sensitive-1, yellow-1, and conidial separation-2 (which marks linkage group VII). All four are readily scored by eye. The strains grow on minimal medium. No transfer to test-media is necessary. Crosses heterozygous for alcoy .have proved useful in cytological studies of the synaptonemal ...
... temperature sensitive-1, yellow-1, and conidial separation-2 (which marks linkage group VII). All four are readily scored by eye. The strains grow on minimal medium. No transfer to test-media is necessary. Crosses heterozygous for alcoy .have proved useful in cytological studies of the synaptonemal ...
Epigenetic Regulation ofbdnfGene Transcription in the
... For all our methylation-specific real-time PCR (MSP) data, we performed bisulfite treatment of genomic DNA an average of 5– 6 times. Bisulfite treatment of genomic DNA converts cytosine to uracil, but leaves methylated 5⬘-cytosines unchanged. Quantitative real-time PCR was used to determine the DNA ...
... For all our methylation-specific real-time PCR (MSP) data, we performed bisulfite treatment of genomic DNA an average of 5– 6 times. Bisulfite treatment of genomic DNA converts cytosine to uracil, but leaves methylated 5⬘-cytosines unchanged. Quantitative real-time PCR was used to determine the DNA ...
Trichothiodystrophy: Update on the sulfur
... Trichothiodystrophy (TTD) refers to a heterogeneous group of autosomal recessive disorders that share the distinctive features of short, brittle hair and an abnormally low sulfur content. Within the spectrum of the TTD syndromes are numerous interrelated neuroectodermal disorders. The TTD syndromes ...
... Trichothiodystrophy (TTD) refers to a heterogeneous group of autosomal recessive disorders that share the distinctive features of short, brittle hair and an abnormally low sulfur content. Within the spectrum of the TTD syndromes are numerous interrelated neuroectodermal disorders. The TTD syndromes ...
In vitro fertilization (IVF) in mammals: epigenetic and developmental
... He named this process Epigenetics, which is now understood as the conditions that control the expression of genes that are highly influenced by environment. A more precise definition is: “The study of changes in gene function that are mitotically and/or meiotically heritable and that do not entail a ...
... He named this process Epigenetics, which is now understood as the conditions that control the expression of genes that are highly influenced by environment. A more precise definition is: “The study of changes in gene function that are mitotically and/or meiotically heritable and that do not entail a ...
Analysis of single nucleotide polymorphisms in human
... groups have predicted the effect of SNPs on the structure of proteins in order to rationalize the effect of SNPs on protein function [8-11]. Wang and Moult showed that SNPs resulting in deleterious amino acid changes predominantly affect the stability of the protein. Sunyaev and coworkers estimate t ...
... groups have predicted the effect of SNPs on the structure of proteins in order to rationalize the effect of SNPs on protein function [8-11]. Wang and Moult showed that SNPs resulting in deleterious amino acid changes predominantly affect the stability of the protein. Sunyaev and coworkers estimate t ...
Microbiology
... Previously, we have reported that MutS-dependent mismatch repair affects phase variation (van den Broek et al., 2003, 2005). MutS is involved in the methyl-directed recognition of DNA mismatches related to replication, which include base mismatches and small insertion and deletion mispairs (Modrich, ...
... Previously, we have reported that MutS-dependent mismatch repair affects phase variation (van den Broek et al., 2003, 2005). MutS is involved in the methyl-directed recognition of DNA mismatches related to replication, which include base mismatches and small insertion and deletion mispairs (Modrich, ...
SALSA MLPA KIT ME003-A1 Tumor suppressor-3 - MRC
... generates two samples that need analysis by capillary electrophoresis: one undigested sample for copy number detection and one digested sample for methylation detection. More information about MS-MLPA can be found on page 2 and in the MS-MLPA protocol. The MS-MLPA probes in this ME003-A1 probemix de ...
... generates two samples that need analysis by capillary electrophoresis: one undigested sample for copy number detection and one digested sample for methylation detection. More information about MS-MLPA can be found on page 2 and in the MS-MLPA protocol. The MS-MLPA probes in this ME003-A1 probemix de ...
Disruption and aberrant expression of HMGA2 as a
... groove of many promoter and enhancer DNA regulatory elements.4 HMG proteins possess no intrinsic transcriptional activity, but instead function to orchestrate the assembly of nucleoprotein structures involved in gene replication, transcription and overall chromatin structure through a complex networ ...
... groove of many promoter and enhancer DNA regulatory elements.4 HMG proteins possess no intrinsic transcriptional activity, but instead function to orchestrate the assembly of nucleoprotein structures involved in gene replication, transcription and overall chromatin structure through a complex networ ...
... All CML have a t(9;22), at least at the molecular level (BCR/ABL); phenotype and stem cell origin: multipotent progenitor: t(9;22) is found in all myeloid and B-lineage progenitors. Prognosis Median survival ≥ 4 yrs; alphaIFN therapy or BMT are indicated. Cytogenetics Anomalies additional to the t(9 ...
lecture - Berkeley MCB
... Explanation (don’t laugh): 1. Protein structure is “dynamic.” 2. When an inducer (lactose) shows up, an existing protein is reorganized from small bits to become active b-galactosidase. MCB 140 11-6-06 16 ...
... Explanation (don’t laugh): 1. Protein structure is “dynamic.” 2. When an inducer (lactose) shows up, an existing protein is reorganized from small bits to become active b-galactosidase. MCB 140 11-6-06 16 ...
XYY Syndrome - Society for the Study of Behavioural Phenotypes
... (Bryant,2012)Increased grey matter may be the result of reduced synaptic pruning, leading to altered synaptic function and perhaps increased seizure risk.(Bardsley, 2014). Voxel MRI documented recently that boys with XYY have lesser WM in the frontal region combined with an increase in GM in the rig ...
... (Bryant,2012)Increased grey matter may be the result of reduced synaptic pruning, leading to altered synaptic function and perhaps increased seizure risk.(Bardsley, 2014). Voxel MRI documented recently that boys with XYY have lesser WM in the frontal region combined with an increase in GM in the rig ...
Export To Word
... independent assortment. This states that genes are inherited independently of one another. This tutorial will help you better understand crossing over and independent assortment during meiosis. This video discusses the phases of Meiosis (Part 1 of 2). This video discusses the phases of Meiosis (Part ...
... independent assortment. This states that genes are inherited independently of one another. This tutorial will help you better understand crossing over and independent assortment during meiosis. This video discusses the phases of Meiosis (Part 1 of 2). This video discusses the phases of Meiosis (Part ...
factor involved in dorsal-ventral axis formation and neurogenesis
... Figure 2. Molecular characterization of spi. (A) Restriction map of the spi region. Genomic DNA encompassing the spi region is indicated by the top line. Arrows above the line mark the boundaries of phage R37. The 2.9-kb BamHI-EcoRI restriction fragment is altered in spi dppta (data not shown). The ...
... Figure 2. Molecular characterization of spi. (A) Restriction map of the spi region. Genomic DNA encompassing the spi region is indicated by the top line. Arrows above the line mark the boundaries of phage R37. The 2.9-kb BamHI-EcoRI restriction fragment is altered in spi dppta (data not shown). The ...
Chromosomes Carrying Meiotic Avoidance Loci
... piloselloides but absent in sexual Hieracium pilosella. Their absence in apomictic Hieracium aurantiacum suggests that meiotic avoidance may have evolved independently in aposporous subgenus Pilosella species. The structure of the hemizygous chromosomal region containing the LOA locus in the three H ...
... piloselloides but absent in sexual Hieracium pilosella. Their absence in apomictic Hieracium aurantiacum suggests that meiotic avoidance may have evolved independently in aposporous subgenus Pilosella species. The structure of the hemizygous chromosomal region containing the LOA locus in the three H ...