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MICR 201 Microbiology for Health Related Sciences
MICR 201 Microbiology for Health Related Sciences

... 15) The antibodies found in mucus, saliva, and tears are A) IgG. B) IgM. C) IgA. D) IgD. E) IgE. 26) The best definition antibody is A) A serum protein. B) A protein that inactivates or kills an antigen. C) A protein made in response to an antigen that can combine with that antigen. D) An immunoglob ...
Διαφάνεια 1 - Aristotle University of Thessaloniki
Διαφάνεια 1 - Aristotle University of Thessaloniki

... 3) Helper T cell recognizes the antigen displayed and binds to the macrophage. ...
biopresibstandards
biopresibstandards

... differences between human cells and bacterial cells and so there are many antibiotics that block a process in bacterial cells without causing any harm to human cells.  Viruses carry out very few processes themselves. They rely instead on a host cell such as a human cell to carry out the processes f ...
1Mono Clonal Antibodies (reviewed)
1Mono Clonal Antibodies (reviewed)

... Rare ---- more serious side effects  Infusion reactions. Severe allergy-like reactions can occur and, in very few cases, lead to death  Dangerously low blood cell counts. Decreased red blood cells, white blood cells and platelets  Cardiac complications Certain monoclonal antibodies may cause hea ...
antigenantibody
antigenantibody

... (specific antigens/antibodies): 1. The pathogen or foreign invader has ANTIGENS on the surface of it’s structure. 2. White blood cells called lymphocytes recognize a foreign invader because of its ANTIGENS and will cause our B cells (types of lymphocytes, white blood cells) to begin to make proteins ...
Hypersensitivities
Hypersensitivities

...  In health, the immune system protects against infections by reacting against foreign proteins.  The immune system recognizes “self” and therefore not attack them.  In autoimmune disease there is a breakdown in the self/non-self recognition system which results in the immune system attacking the ...
Immunity
Immunity

... Agglutination: antibodies clump the antigens together which are later destroyed by phagocytes. Precipitation: soluble antigens are preciptated and destroyed by the phagocytes. Opsonization: antibodies are coated on microbial surface after which antigen locks in. This makes it more susceptible to pha ...
sheet of notes
sheet of notes

... • Defends against free bacteria, toxins, and viruses present in body fluids • The repeated subunits of these antigens bind simultaneously to a number of membrane antibodies on the B cell surface Cell-mediated immunity • Active against bacteria and viruses within infected body cells and against fungi ...
- EBioMedicine
- EBioMedicine

... after reexposure to antigen and so could produce antibodies only after infection had occurred. It is uncertain whether a new infection in a mucosal epithelium would generate enough virion antigen to activate systemic Bmen in a timely fashion and if it did, whether it would prevent neoplastic progres ...
Molecular and Cellular Immunology/Immunology
Molecular and Cellular Immunology/Immunology

... • Concept dates to 430 B.C. when Thucydides, the historian of the Peloponnesian War, wrote that those who had recovered from Plague could care for those with disease • Variolation - used in ancient Asia; brought to Europe in 1721 by Lady Mary Wortley and subsequently used in the Revolutionary War • ...
Immune System Reading Notes Nonspecific Defenses and External
Immune System Reading Notes Nonspecific Defenses and External

... Most antigens are Some can also be ...
Immune_11
Immune_11

... attack moist areas, like the skin, scalp, mouth & throat ex: ringworms & athlete’s foot ...
Nanotechnology & Nanobiotechnology
Nanotechnology & Nanobiotechnology

... Monoclonal Antibodies – These are antibodies (抗體) made in the lab that can target antigens (抗原) with extreme specificity. They are attached to a drug in order to guide it to a specific cell. For example, cancer drugs can be attached to monoclonal antibodies made against tumour cells, which helps the ...
A138PN AFFINITY PURIFIED ANTIBODIES
A138PN AFFINITY PURIFIED ANTIBODIES

... 1: 10,000 by direct ELISA. Optimal working dilution must be determined by end user in their individual assay system. ...
Abstract
Abstract

... Department of Life Science, Gwangju Institute of Science and Technology, 1 Oryong-dong, Puk-ku, Gwangju 500-712 Korea Attacking of self-components by auto-reactive T cells and/or B cells causes a damage or loss of organ function resulting in diverse immune disorders. Autonomic neuropathies often cau ...
Lymphatic System
Lymphatic System

... – Occurs if not enough drainage, or too much produced – Can cause tissue damage and death ...
Immunoglobulin and Monoclonal antibodies
Immunoglobulin and Monoclonal antibodies

... Immunoglobulin's are glycoprotein molecules that are produced by plasma cells in response to an immunogen and which function as antibodies. The immunoglobulins derive their name from the finding that they migrate with globular proteins when antibody-containing serum is placed in an electrical field ...
Monoclonal antibodies-anticancer therapy
Monoclonal antibodies-anticancer therapy

... are grouped into five classes, or isotypes: IgG, IgA, IgM, IgD, and IgE. IgG: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%) , blood and tissue liquid. IgA:IgA1 (90%) and IgA2 (10%), stomach and intestines IgM: normally pentamer, ocassionally hexamer, multiple immunoglobins linked with ...
File
File

... bacteria or viruses which can still act as an antigen. Because the cell is weakened or dead it can no longer cause the disease. The immune system responds to it by producing antibodies or T cells. The memory cells will remain in your body for a long period of time giving you immunity to that disease ...
unit8 immune response
unit8 immune response

... recognize a foreign agent as nonself, which is something other than a person's own substances (self). The immune system takes a specific action for neutralizing, killing, and eliminating that agent. ...
Anatomy - Immune system - UK College of Agriculture
Anatomy - Immune system - UK College of Agriculture

... better understood when the non-specific immune mechanisms are taken into consideration. For example: the overuse of antibiotics or poor sanitation may lead to a disruption of the normal microflora; poor nutrition may lead to deficiencies which allow disease organisms to penetrate the protective body ...
Self tolerance
Self tolerance

... Cell injury (e. g., UV and other environmental insults) leads to apoptosis and an increased burden of nuclear antigens(due to defective clearance of nuclear antigens) . ...
Secondary Immune Response
Secondary Immune Response

... Process of clonal selection explain why/how adaptive immune response act against any antigen. •Lymphocyte developed –with antigen receptor. •Then speciallized into B-cell receptor and T-cell receptor. •The receptor can react with specific epitopes of an antigen. •Each of receptor is different /iden ...
Biology 2201
Biology 2201

... Process of clonal selection explain why/how adaptive immune response act against any antigen. •Lymphocyte developed –with antigen receptor. •Then speciallized into B-cell receptor and T-cell receptor. •The receptor can react with specific epitopes of an antigen. •Each of receptor is different /iden ...
Acquired immunity
Acquired immunity

... Various specialized regions in the body produce immune system components. Humoral immunity is part of acquired immunity and relies on production of antibodies to attack pathogens. A small number of “memory” cells continually patrol the blood and produce antibodies in case of later infection. Cell- ...
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Anti-nuclear antibody



Antinuclear antibodies (ANAs, also known as antinuclear factor or ANF) are autoantibodies that bind to contents of the cell nucleus. In normal individuals, the immune system produces antibodies to foreign proteins (antigens) but not to human proteins (autoantigens). In some individuals, antibodies to human antigens are produced.There are many subtypes of ANAs such as anti-Ro antibodies, anti-La antibodies, anti-Sm antibodies, anti-nRNP antibodies, anti-Scl-70 antibodies, anti-dsDNA antibodies, anti-histone antibodies, antibodies to nuclear pore complexes, anti-centromere antibodies and anti-sp100 antibodies. Each of these antibody subtypes binds to different proteins or protein complexes within the nucleus. They are found in many disorders including autoimmunity, cancer and infection, with different prevalences of antibodies depending on the condition. This allows the use of ANAs in the diagnosis of some autoimmune disorders, including systemic lupus erythematosus, Sjögren's syndrome, scleroderma, mixed connective tissue disease, polymyositis, dermatomyositis, autoimmune hepatitis and drug induced lupus.The ANA test detects the autoantibodies present in an individual's blood serum. The common tests used for detecting and quantifying ANAs are indirect immunofluorescence and enzyme-linked immunosorbent assay (ELISA). In immunofluorescence, the level of autoantibodies is reported as a titre. This is the highest dilution of the serum at which autoantibodies are still detectable. Positive autoantibody titres at a dilution equal to or greater than 1:160 are usually considered as clinically significant. Positive titres of less than 1:160 are present in up to 20% of the healthy population, especially the elderly. Although positive titres of 1:160 or higher are strongly associated with autoimmune disorders, they are also found in 5% of healthy individuals. Autoantibody screening is useful in the diagnosis of autoimmune disorders and monitoring levels helps to predict the progression of disease. A positive ANA test is seldom useful if other clinical or laboratory data supporting a diagnosis are not present.
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