New drugs for hepatitis C
... Nakamoto, S., Kanda, T., Wu, S., Shirasawa, H., & Yokosuka, O. (2014). Hepatitis C virus NS5A inhibitors and drug resistance mutations. World Journal of Gastroenterology : WJG, 20(11), 2902–2912. ...
... Nakamoto, S., Kanda, T., Wu, S., Shirasawa, H., & Yokosuka, O. (2014). Hepatitis C virus NS5A inhibitors and drug resistance mutations. World Journal of Gastroenterology : WJG, 20(11), 2902–2912. ...
Persistent infection of mammalian cells by Rift Valley fever virus
... virus production were observed with two other persistently infected cell lines obtained after infection with these strains. As the production of infectious virus decreased, the plaque size diminished, suggesting that the particles produced were less and less cytopathic. This was confirmed by titrati ...
... virus production were observed with two other persistently infected cell lines obtained after infection with these strains. As the production of infectious virus decreased, the plaque size diminished, suggesting that the particles produced were less and less cytopathic. This was confirmed by titrati ...
Atlantic salmon type I interferons: Protection against virus infection in
... Fish farming have been considered the importance resource for supplying food for global requirement (1). Norway by far is the country that produce the most salmon in the world, and virus disease is one of the major problems that causes the economic loss in fish farming. For combating the diseases, v ...
... Fish farming have been considered the importance resource for supplying food for global requirement (1). Norway by far is the country that produce the most salmon in the world, and virus disease is one of the major problems that causes the economic loss in fish farming. For combating the diseases, v ...
Conservation of L and 3C proteinase activities across distantly
... FMDV, although ERAV VP1 does appear to bind host receptors (Warner et al., 2001). On the other hand, the IRES elements of ERAV and FMDV appear to function similarly (Hinton et al., 2000). Here, we describe an investigation into the function of the leader (L) and 3C proteinases of ERAV. We have also ...
... FMDV, although ERAV VP1 does appear to bind host receptors (Warner et al., 2001). On the other hand, the IRES elements of ERAV and FMDV appear to function similarly (Hinton et al., 2000). Here, we describe an investigation into the function of the leader (L) and 3C proteinases of ERAV. We have also ...
Biology Division, National Cancer Center Research Institute Tsukiji
... I966). One difference, however, is that a much higher multiplicity of u.v.-VSV is required to obtain sufficient shut-off than that required with the INDIANA serotype of VSV and suspensions of Krebs-a cells (Wagner & Huang, 1966). It is not yet clear whether this discrepancy is due to differences in ...
... I966). One difference, however, is that a much higher multiplicity of u.v.-VSV is required to obtain sufficient shut-off than that required with the INDIANA serotype of VSV and suspensions of Krebs-a cells (Wagner & Huang, 1966). It is not yet clear whether this discrepancy is due to differences in ...
Keratinocytes derived from chicken embryonic
... addressing the dissemination of both viruses in primary CESCs [22] and clusters of C capsids were observed in cytoplasm of infected K-cESCs, indicating that deenvelopment and/or C capsid nuclear egress took place in K-cESCs. MDV has been reported to be impaired in secondary envelopment step in prima ...
... addressing the dissemination of both viruses in primary CESCs [22] and clusters of C capsids were observed in cytoplasm of infected K-cESCs, indicating that deenvelopment and/or C capsid nuclear egress took place in K-cESCs. MDV has been reported to be impaired in secondary envelopment step in prima ...
Interferon
Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and also tumor cells. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.IFNs belong to the large class of proteins known as cytokines, molecules used for communication between cells to trigger the protective defenses of the immune system that help eradicate pathogens. Interferons are named for their ability to ""interfere"" with viral replication by protecting cells from virus infections. IFNs also have various other functions: they activate immune cells, such as natural killer cells and macrophages; they increase host defenses by up-regulating antigen presentation by virtue of increasing the expression of major histocompatibility complex (MHC) antigens. Certain symptoms of infections, such as fever, muscle pain and ""flu-like symptoms"", are also caused by the production of IFNs and other cytokines.More than twenty distinct IFN genes and proteins have been identified in animals, including humans. They are typically divided among three classes: Type I IFN, Type II IFN, and Type III IFN. IFNs belonging to all three classes are important for fighting viral infections and for the regulation of the immune system.