CEREBRAL CORTEX - Oxford Academic
... what are the mechanisms that produce them, and what are the functional sequelae of differential brain aging? In this report, we examine the topography of age-related structural differences in the human cerebral cortex using in vivo evidence from magnetic resonance imaging (MRI), and offer some specu ...
... what are the mechanisms that produce them, and what are the functional sequelae of differential brain aging? In this report, we examine the topography of age-related structural differences in the human cerebral cortex using in vivo evidence from magnetic resonance imaging (MRI), and offer some specu ...
An Olfactory Sensory Map in the Fly Brain
... is represented in the antennal lobe. However, in the absence of the genes encoding the receptor molecules, it has not been possible to define a physical basis for this spatial map. In this study we have identified the “complete” family of Drosophila odorant receptors (DORs) and employ these genes to ...
... is represented in the antennal lobe. However, in the absence of the genes encoding the receptor molecules, it has not been possible to define a physical basis for this spatial map. In this study we have identified the “complete” family of Drosophila odorant receptors (DORs) and employ these genes to ...
2012 Year In Review - UCSF Neurosurgery
... like to congratulate our adult neurooncology team for winning the UCSF Medical Center’s Pinnacle Award for an unprecedented fifth year in a row. The Pinnacle Award recognizes the outpatient service with the highest patient satisfaction scores. The neuro-oncology team has also been joined by a remark ...
... like to congratulate our adult neurooncology team for winning the UCSF Medical Center’s Pinnacle Award for an unprecedented fifth year in a row. The Pinnacle Award recognizes the outpatient service with the highest patient satisfaction scores. The neuro-oncology team has also been joined by a remark ...
Human brain spots emotion in non humanoid
... expression at a latency of 90 ms, and differentiating monkey identity about 70 ms later (Sugase et al., 1999). These delays meet P1 and N170 visual components latencies in human EEG studies, with the P1 wave being modulated by emotion, and the N170 wave being mainly modulated by facial configuration ...
... expression at a latency of 90 ms, and differentiating monkey identity about 70 ms later (Sugase et al., 1999). These delays meet P1 and N170 visual components latencies in human EEG studies, with the P1 wave being modulated by emotion, and the N170 wave being mainly modulated by facial configuration ...
Neural Substrate Expansion for the Restoration of Brain
... computational capacity of the brain is augmented through the addition of new processing units and the reconstitution of network connectivity. This latter approach has been explored to some degree using both biological and electronic means but thus far has not demonstrated the ability to reestablish ...
... computational capacity of the brain is augmented through the addition of new processing units and the reconstitution of network connectivity. This latter approach has been explored to some degree using both biological and electronic means but thus far has not demonstrated the ability to reestablish ...
Physiology of functional and effective networks in epilepsy
... dynamics are thus generally constrained by the underlying structural networks on which they unfold. Inspired by the effort to sequence the human genetic code to build a genome, recent efforts in brain research have aimed at developing a comprehensive map of global brain connectivity termed the conne ...
... dynamics are thus generally constrained by the underlying structural networks on which they unfold. Inspired by the effort to sequence the human genetic code to build a genome, recent efforts in brain research have aimed at developing a comprehensive map of global brain connectivity termed the conne ...
Summary
... neurosecretory centres in the cerebral ganglia of earthworms in the first month after hatching. It was revealed that the neurosecretory cells are active in the cerebral ganglia of D. veneta already on the day of hatching. Within the first month after hatching, the neurosecretion content increased in ...
... neurosecretory centres in the cerebral ganglia of earthworms in the first month after hatching. It was revealed that the neurosecretory cells are active in the cerebral ganglia of D. veneta already on the day of hatching. Within the first month after hatching, the neurosecretion content increased in ...
Supplementary Information (doc 2155K)
... (zt - zt-1)2 + (at - at-1)2 + (bt - bt-1)2 + (ct - ct-1)2)-1/2. Using this criterion, no volumes were censored for any of the young monkeys. Quantifying Intrinsic Functional Connectivity Given our aims, we adopted a standard a priori seed-based approach to quantifying intrinsic functional connectivi ...
... (zt - zt-1)2 + (at - at-1)2 + (bt - bt-1)2 + (ct - ct-1)2)-1/2. Using this criterion, no volumes were censored for any of the young monkeys. Quantifying Intrinsic Functional Connectivity Given our aims, we adopted a standard a priori seed-based approach to quantifying intrinsic functional connectivi ...
A Review of the Relationship between Proinflammatory Cytokines
... Chemokines are proteins with chemoattractant properties that act as mediators of the immune-inflammatory reaction and regulate leukocyte infiltration into the brain parenchyma during disease states (Banisadr et al., 2005). As such, they are necessary in the propagation of inflammation and subsequen ...
... Chemokines are proteins with chemoattractant properties that act as mediators of the immune-inflammatory reaction and regulate leukocyte infiltration into the brain parenchyma during disease states (Banisadr et al., 2005). As such, they are necessary in the propagation of inflammation and subsequen ...
スライド 1 - Weill Cornell Medical College in Qatar
... Mendelian fashion. Here, we perform whole exome sequencing to search for rare, causal mutations in a 4-generation, 49-person consanguineous Syrian pedigree in which 8 individuals were affected with rheumatoid arthritis (RA). Method: We performed GWAS genotyping on 16 family members (affected and una ...
... Mendelian fashion. Here, we perform whole exome sequencing to search for rare, causal mutations in a 4-generation, 49-person consanguineous Syrian pedigree in which 8 individuals were affected with rheumatoid arthritis (RA). Method: We performed GWAS genotyping on 16 family members (affected and una ...
Serotonergic Psychedelics Temporarily Modify Information Transfer
... preceded and followed at 1.5 and 2.5 hours, respectively, by significant decreases. The directionality of change is shown in the figure below the connection maps. Topographic representations of the source and sink areas show that TE increases at 2 hours were governed by information originating at po ...
... preceded and followed at 1.5 and 2.5 hours, respectively, by significant decreases. The directionality of change is shown in the figure below the connection maps. Topographic representations of the source and sink areas show that TE increases at 2 hours were governed by information originating at po ...
The elephant brain in numbers
... What explains the superior cognitive abilities of the human brain, with richly complex and flexible behaviors, compared to other brains (Premack, 2007), some even larger than ours (Roth and Dicke, 2005)? Neuroanatomical correlates have been sought in total brain mass, cerebral cortical mass and cort ...
... What explains the superior cognitive abilities of the human brain, with richly complex and flexible behaviors, compared to other brains (Premack, 2007), some even larger than ours (Roth and Dicke, 2005)? Neuroanatomical correlates have been sought in total brain mass, cerebral cortical mass and cort ...
Mutations in the X-linked filamin 1 gene cause periventricular
... PH, single-strand conformation polymorphism (SSCP) mutational analysis was performed on all 48 coding exons of the FLN1 gene in six pedigrees (all of which showed PH inherited from female to female) and 31 PH females with no evidence of inherited PH by family history. The primers used to amplify the ...
... PH, single-strand conformation polymorphism (SSCP) mutational analysis was performed on all 48 coding exons of the FLN1 gene in six pedigrees (all of which showed PH inherited from female to female) and 31 PH females with no evidence of inherited PH by family history. The primers used to amplify the ...
Association genetics
... relationships between genetic markers and phenotypic traits – Two approaches for grouping individuals – By phenotype (e.g., healthy vs. disease) – By marker genotype (similar to approach used in QTL studies) – Two approaches for selecting markers for evaluation – Candidate gene – Whole genome ...
... relationships between genetic markers and phenotypic traits – Two approaches for grouping individuals – By phenotype (e.g., healthy vs. disease) – By marker genotype (similar to approach used in QTL studies) – Two approaches for selecting markers for evaluation – Candidate gene – Whole genome ...
CHAPTER 3 Neuroscience and Behavior
... Before a neuron is triggered—that is, when it is in a resting state—it has a negative electrical charge of about 270 millivolts (a millivolt is one one-thousandth of a volt). This charge is caused by the presence of more negatively charged ions within the neuron than outside it. (An ion is an atom t ...
... Before a neuron is triggered—that is, when it is in a resting state—it has a negative electrical charge of about 270 millivolts (a millivolt is one one-thousandth of a volt). This charge is caused by the presence of more negatively charged ions within the neuron than outside it. (An ion is an atom t ...
Brain Evolution Relevant to Language
... The evolution of language obviously presupposes a brain that made language possible. At the same time, given the fundamental importance language has to the human condition, a critical driving force of the evolution of the human brain must have been language. Given that language is at least as much a ...
... The evolution of language obviously presupposes a brain that made language possible. At the same time, given the fundamental importance language has to the human condition, a critical driving force of the evolution of the human brain must have been language. Given that language is at least as much a ...
Cortico-Basal Ganglia Interactions in Huntington`s Disease
... (associated with early stages of HD) and dyskinetic movements (associated with advanced HD). Loss of “indirect” GABA/ENK striato-pallidal fibres, that project from the striatum to the GPe leads to a reduction in the inhibitory action upon GPe, which results in over activation of the GABAergic neuron ...
... (associated with early stages of HD) and dyskinetic movements (associated with advanced HD). Loss of “indirect” GABA/ENK striato-pallidal fibres, that project from the striatum to the GPe leads to a reduction in the inhibitory action upon GPe, which results in over activation of the GABAergic neuron ...
AbPsych Chapter 2 Handouts
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AandPChp7Brain
... Cerebrovascular Accident (CVA) or Stroke •Result from a ruptured blood vessel supplying a region of the brain •Brain tissue supplied with oxygen from that blood source dies •Loss of some functions or death may result •Hemiplegia One-sided paralysis •Aphasis Damage to speech center in left hemis ...
... Cerebrovascular Accident (CVA) or Stroke •Result from a ruptured blood vessel supplying a region of the brain •Brain tissue supplied with oxygen from that blood source dies •Loss of some functions or death may result •Hemiplegia One-sided paralysis •Aphasis Damage to speech center in left hemis ...
3 Behavioral Neuroscience - McGraw Hill Higher Education
... on the threshold of identifying genes that affect behavior (Plomin & Crabbe, 2000). For example, the ambitious Human Genome Project aims to identify the structure and functions of all human genes, with scientists estimating that there are more than 30,000 genes to be identified. Most researchers in ...
... on the threshold of identifying genes that affect behavior (Plomin & Crabbe, 2000). For example, the ambitious Human Genome Project aims to identify the structure and functions of all human genes, with scientists estimating that there are more than 30,000 genes to be identified. Most researchers in ...
Mutation discovery for Mendelian traits in nonlaboratory animals: a
... first success story in non-laboratory animals, the obvious candidate molecule being the peptide thyroglobulin (TG). Tellingly, all authors of the three key papers (Tassi et al. 1984; Ricketts et al. 1985, 1987) were working in human medical research laboratories (in Naples, Cape Town and Brussels). ...
... first success story in non-laboratory animals, the obvious candidate molecule being the peptide thyroglobulin (TG). Tellingly, all authors of the three key papers (Tassi et al. 1984; Ricketts et al. 1985, 1987) were working in human medical research laboratories (in Naples, Cape Town and Brussels). ...
What is a Brain State
... intuitive account of what we expect brain states to be as well as a convincing argument against a common candidate for knowledge about brain states which is currently ‘on the scene.’ I then introduce a distinction between brain states and states of the brain (cf. Chalmers’ specific and background NC ...
... intuitive account of what we expect brain states to be as well as a convincing argument against a common candidate for knowledge about brain states which is currently ‘on the scene.’ I then introduce a distinction between brain states and states of the brain (cf. Chalmers’ specific and background NC ...
The locus of sexual selection: moving sexual selection studies into
... adaptation, and these approaches have generally been lacking from many sexual selection studies. Below, we describe several different genomic approaches that have been or could be used to discover genetic variants underlying variation in sexually selected phenotypes, and identify methods and experim ...
... adaptation, and these approaches have generally been lacking from many sexual selection studies. Below, we describe several different genomic approaches that have been or could be used to discover genetic variants underlying variation in sexually selected phenotypes, and identify methods and experim ...
Data Supplement
... training run. Post stroke testing was performed with one run per mouse. Ladder test performance was scored as the percent correct steps and the total number of left front foot missteps. Automated gait analysis. Mice were trained on the automated gait analysis apparatus (Noldus Catwalk). This test wa ...
... training run. Post stroke testing was performed with one run per mouse. Ladder test performance was scored as the percent correct steps and the total number of left front foot missteps. Automated gait analysis. Mice were trained on the automated gait analysis apparatus (Noldus Catwalk). This test wa ...
Chordate evolution and the origin of craniates
... elaborated brains with paired sense organs and unique derivatives of neural crest and placodal tissues, including peripheral sensory ganglia, visceral arches, and head skeleton. The craniate sister taxon, cephalochordates, has rostral portions of the neuraxis that are homologous to some of the major ...
... elaborated brains with paired sense organs and unique derivatives of neural crest and placodal tissues, including peripheral sensory ganglia, visceral arches, and head skeleton. The craniate sister taxon, cephalochordates, has rostral portions of the neuraxis that are homologous to some of the major ...