Assessing similarity to primary tissue and cortical layer identity in
... in human samples from patients affected by such diseases and, importantly, how disease progresses over time (1). Protocols have been developed capable of generating cortical cells from human iPSCs, which appear to adopt specific cortical layer identities and develop functional synapses (2–6). Most tr ...
... in human samples from patients affected by such diseases and, importantly, how disease progresses over time (1). Protocols have been developed capable of generating cortical cells from human iPSCs, which appear to adopt specific cortical layer identities and develop functional synapses (2–6). Most tr ...
Genetic Analysis of Human Traits In Vitro: Drug Response and Gene
... plates. These replicate measurements for each cell line allowed assessment of intra-experimental variation. To evaluate day-to-day (i.e. inter-experimental) variation in all traits, a subset of 90 cell lines (30 from each of the three HapMap panels) was grown from freshly thawed aliquots and the ent ...
... plates. These replicate measurements for each cell line allowed assessment of intra-experimental variation. To evaluate day-to-day (i.e. inter-experimental) variation in all traits, a subset of 90 cell lines (30 from each of the three HapMap panels) was grown from freshly thawed aliquots and the ent ...
Mate pair sequencing for the detection of chromosomal aberrations
... improvement compared to conventional karyotyping. The genetic cause remains however ...
... improvement compared to conventional karyotyping. The genetic cause remains however ...
Developmental regulation and individual differences of neuronal
... evelopmentally regulated changes in histone modifications and DNA methylation, shaping gene expression patterns and genome organization, are critical intermediates for numerous genetic and environmental factors affecting neuronal functions in healthy and diseased brains (1). For example, there is inc ...
... evelopmentally regulated changes in histone modifications and DNA methylation, shaping gene expression patterns and genome organization, are critical intermediates for numerous genetic and environmental factors affecting neuronal functions in healthy and diseased brains (1). For example, there is inc ...
Neural Correlates of Human Virtue Judgment
... judgment of moral beauty and depravity would show different brain activation patterns. Specifically, moral depravity would be linked to brain regions, such as pSTS and MPFC, and moral beauty would recruit the brain regions implicated in positive emotions, such as OFC. Materials and Methods Participan ...
... judgment of moral beauty and depravity would show different brain activation patterns. Specifically, moral depravity would be linked to brain regions, such as pSTS and MPFC, and moral beauty would recruit the brain regions implicated in positive emotions, such as OFC. Materials and Methods Participan ...
Magnetic resonance imaging indicators of blood
... Quantitative diffusion maps were measured using magnetization-prepared TurboFLASH as modified by Thomas and coworkers [35]. It consists of a drivenequilibrium Fourier transform (DEFT) sequence with a pair of diffusion-sensitizing gradients around the 180° refocusing RF pulse followed by the TurboFLA ...
... Quantitative diffusion maps were measured using magnetization-prepared TurboFLASH as modified by Thomas and coworkers [35]. It consists of a drivenequilibrium Fourier transform (DEFT) sequence with a pair of diffusion-sensitizing gradients around the 180° refocusing RF pulse followed by the TurboFLA ...
The Neuropsychology of Reading Disorders
... 3. A discrepancy model of reading disabilities precludes early identification. 4. Intelligence is more a predictor of school success, and not necessarily a predictor of successful reading. 5. There is little evidence to suggest that poor readers on the lower end of the reading distribution differ fr ...
... 3. A discrepancy model of reading disabilities precludes early identification. 4. Intelligence is more a predictor of school success, and not necessarily a predictor of successful reading. 5. There is little evidence to suggest that poor readers on the lower end of the reading distribution differ fr ...
Objectives
... b) Discuss the relationship between methylphenidate use in childhood and drug abuse in adulthood. c) Describe the effects of MDMA on the brain and on behavior. d) Describe the effects of nicotine on the brain. e) Identify three types of opiates and describe their effects on behavior. f) Summarize th ...
... b) Discuss the relationship between methylphenidate use in childhood and drug abuse in adulthood. c) Describe the effects of MDMA on the brain and on behavior. d) Describe the effects of nicotine on the brain. e) Identify three types of opiates and describe their effects on behavior. f) Summarize th ...
Introduction to Psychology
... Lesson I-11: Structure of the Vertebrate Nervous System (Part 1) Objectives: ...
... Lesson I-11: Structure of the Vertebrate Nervous System (Part 1) Objectives: ...
Inferring a dual-stream model of mentalizing from associative white
... slight slowing of the inferential process associated with intentional attribution (Herbet et al., 2013). Based on these findings, we assumed that both tasks can simultaneously engage the mirror and mentalizing systems to some extent, but that the intactness of each subsystem is more important for su ...
... slight slowing of the inferential process associated with intentional attribution (Herbet et al., 2013). Based on these findings, we assumed that both tasks can simultaneously engage the mirror and mentalizing systems to some extent, but that the intactness of each subsystem is more important for su ...
Preview Sample 1
... D. Neural Plasticity and Neurogenesis i. Neural Plasticity: the ability of the brain to change in response to experience ii. Neurogenesis: Production of new brain cells, the growth of new neurons II. The Central Nervous System A. The Organization of the Nervous System i. Central Nervous System (Lect ...
... D. Neural Plasticity and Neurogenesis i. Neural Plasticity: the ability of the brain to change in response to experience ii. Neurogenesis: Production of new brain cells, the growth of new neurons II. The Central Nervous System A. The Organization of the Nervous System i. Central Nervous System (Lect ...
Cognition without a Neural Code: How a Folded Electromagnetic Fields
... how modification of synapses while thought is in progress can turn a mass of electrical activity into thought. Synaptic change does not proceed at the rate humans think, but over many seconds and even over days and months (Donoghue 1995). While synaptic modulation is indispensible for learning, how ...
... how modification of synapses while thought is in progress can turn a mass of electrical activity into thought. Synaptic change does not proceed at the rate humans think, but over many seconds and even over days and months (Donoghue 1995). While synaptic modulation is indispensible for learning, how ...
Denes et al. 2007 - Philosophical Transactions of the Royal Society B
... what their initial structure and function was. It is also unclear whether the CNS of vertebrates and invertebrates trace back to a common CNS precursor (Arendt & Nübler-Jung 1999) or whether they are of independent evolutionary origin (Holland 2003; Lowe et al. 2003). This review addresses the ques ...
... what their initial structure and function was. It is also unclear whether the CNS of vertebrates and invertebrates trace back to a common CNS precursor (Arendt & Nübler-Jung 1999) or whether they are of independent evolutionary origin (Holland 2003; Lowe et al. 2003). This review addresses the ques ...
EM algorithm
... the main interest was in diseases, but the techniques can be applied to try to find the genes associated with any trait of interest, for example height and longetivity, as well as more traditional diseases like Alzheimer’s disease, macular degeneration, and asthma. In many cases, it is believed that ...
... the main interest was in diseases, but the techniques can be applied to try to find the genes associated with any trait of interest, for example height and longetivity, as well as more traditional diseases like Alzheimer’s disease, macular degeneration, and asthma. In many cases, it is believed that ...
The Nervous System
... Studying Brain Function – Electroencephalography (EEG) • Measures electrical activity – Computerized tomography (CT) scans • Computer-enhanced X-rays ...
... Studying Brain Function – Electroencephalography (EEG) • Measures electrical activity – Computerized tomography (CT) scans • Computer-enhanced X-rays ...
Disproportion of cerebral surface areas and volumes in
... The imaging and segmentation protocols have been described in detail previously (Sisodiya et al., 1995). Briefly, all subjects were scanned using sagittal T1-weighted, coronal T1-weighted volumetric, axial T2-weighted and axial proton density ...
... The imaging and segmentation protocols have been described in detail previously (Sisodiya et al., 1995). Briefly, all subjects were scanned using sagittal T1-weighted, coronal T1-weighted volumetric, axial T2-weighted and axial proton density ...
Genetic basis of male sexual behavior
... elegans mating behavioral program consists of an ordered series of steps, each comprising a set of simple motor actions. Execution of each step is triggered by sensory inputs and tends to lead to acquisition of new inputs that will trigger an advance of the program to the next step. However, the ord ...
... elegans mating behavioral program consists of an ordered series of steps, each comprising a set of simple motor actions. Execution of each step is triggered by sensory inputs and tends to lead to acquisition of new inputs that will trigger an advance of the program to the next step. However, the ord ...
Brain Facts: A Primer On The Brain And Nervous System
... axons, which can range in length from a tiny fraction of an inch to three feet or more. Many axons are covered with a layered myelin sheath, which speeds the transmission of electrical signals along the ...
... axons, which can range in length from a tiny fraction of an inch to three feet or more. Many axons are covered with a layered myelin sheath, which speeds the transmission of electrical signals along the ...
Neuronal Migration and Ventral Subtype Identity in the
... are involved in the emergence of neuronal subtypes in the ventral telencephalon, and whether different transcription factors with neuron-specific expression are required. The SOX proteins constitute a family of transcription factors [19,20] that regulate transcription through their ability to bind to ...
... are involved in the emergence of neuronal subtypes in the ventral telencephalon, and whether different transcription factors with neuron-specific expression are required. The SOX proteins constitute a family of transcription factors [19,20] that regulate transcription through their ability to bind to ...
Multimodality Imaging
... noted that in that most tomographic imaging methods have a relatively course resolution, the observed effects reflect the averaged activity of thousands or millions of neurons. This will require new modeling approaches, in which local populations of neurons are treated as statistical ensembles, for ...
... noted that in that most tomographic imaging methods have a relatively course resolution, the observed effects reflect the averaged activity of thousands or millions of neurons. This will require new modeling approaches, in which local populations of neurons are treated as statistical ensembles, for ...
The genome sequence of the corn snake (Pantherophis guttatus), a
... ABSTRACT Squamates (snakes and lizards) exhibit a striking variety of phenotypes, with little known on their generative mechanisms. Studies aiming to understand the genetic basis of this wide diversity in morphology, physiology and ecology will greatly benefit from whole genome sequencing initiative ...
... ABSTRACT Squamates (snakes and lizards) exhibit a striking variety of phenotypes, with little known on their generative mechanisms. Studies aiming to understand the genetic basis of this wide diversity in morphology, physiology and ecology will greatly benefit from whole genome sequencing initiative ...
Interpreting noncoding genetic variation in complex traits and
... haplotypes, which could be genotyped using chip technology. The stage was set for a flood of unbiased, genome-wide association studies (GWAS) to search across unrelated individuals10 for common variants associated with complex disease and diverse molecular phenotypes (Fig. 1, Table 2). Relative to l ...
... haplotypes, which could be genotyped using chip technology. The stage was set for a flood of unbiased, genome-wide association studies (GWAS) to search across unrelated individuals10 for common variants associated with complex disease and diverse molecular phenotypes (Fig. 1, Table 2). Relative to l ...
Neurons
... assemblages of cells form intricate circuits in the brain that allow us to interpret the world around us and respond to external stimuli, as well as to organize our behavior, think, feel, and use language. Neurons accomplish these tasks by sending messages to one another. Let us break down the proce ...
... assemblages of cells form intricate circuits in the brain that allow us to interpret the world around us and respond to external stimuli, as well as to organize our behavior, think, feel, and use language. Neurons accomplish these tasks by sending messages to one another. Let us break down the proce ...
LEAP - Life Enrichment Center
... from a number of different studies and found 3.5% of Isle of Wight 10-year-olds, 4.5% of 14year-olds and over 6% of London 10-year-olds showed reading difficulties.9 Gaddes looked at the proportion of children with learning disorders in various studies in both North America and Europe and found that ...
... from a number of different studies and found 3.5% of Isle of Wight 10-year-olds, 4.5% of 14year-olds and over 6% of London 10-year-olds showed reading difficulties.9 Gaddes looked at the proportion of children with learning disorders in various studies in both North America and Europe and found that ...
view
... Neurolinguistic research has been engaged in evaluating models of language using measures from brain structure and function, and/or in investigating brain structure and function with respect to language representation using proposed models of language. While the aphasiological strategy, which classi ...
... Neurolinguistic research has been engaged in evaluating models of language using measures from brain structure and function, and/or in investigating brain structure and function with respect to language representation using proposed models of language. While the aphasiological strategy, which classi ...