Emotion in the perspective of an integrated nervous system 1
... leading cause of human suffering, from those conditions triggered by acquired brain damage to those, such as mood disorders, whose genetic and developmental origin is less ...
... leading cause of human suffering, from those conditions triggered by acquired brain damage to those, such as mood disorders, whose genetic and developmental origin is less ...
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... mouse genomes) (Bejerano et al., 2004). The 182-SNP was found to be part of a completely conserved 8 bp motif based on the sequence conservation between 40 vertebrate genomes (Fig. 1). Therefore, the unexpected identification of this SNP in the I56i enhancer suggested that it could have functional c ...
... mouse genomes) (Bejerano et al., 2004). The 182-SNP was found to be part of a completely conserved 8 bp motif based on the sequence conservation between 40 vertebrate genomes (Fig. 1). Therefore, the unexpected identification of this SNP in the I56i enhancer suggested that it could have functional c ...
Contemporary Research in Human Genomics
... • SNPs most common type of human genome variant by number (10-15 Million) • Stable, easy to assay, accurately genotype • Able to multiplex 1000’s of SNPs into same assay Illumina 1M-Duo Affymetrix Human 6.0 906,000 SNPS 946,00 probes for CNV ...
... • SNPs most common type of human genome variant by number (10-15 Million) • Stable, easy to assay, accurately genotype • Able to multiplex 1000’s of SNPs into same assay Illumina 1M-Duo Affymetrix Human 6.0 906,000 SNPS 946,00 probes for CNV ...
alzheimer-like changes of protein kinase b and glycogen synthase
... brain state, streptozotocin (STZ) intracerebroventricularly (icv) treated rat has become one of the proposed experimental models (Hoyer, 2004; Lannert and Hoyer, 1998; Prickaerts et al., 1999; Sharma and Gupta 2001). Namely, STZ is a drug selectively toxic for insulinproducing/secreting cells, which ...
... brain state, streptozotocin (STZ) intracerebroventricularly (icv) treated rat has become one of the proposed experimental models (Hoyer, 2004; Lannert and Hoyer, 1998; Prickaerts et al., 1999; Sharma and Gupta 2001). Namely, STZ is a drug selectively toxic for insulinproducing/secreting cells, which ...
A SIMPLE pipeline for mapping point mutations
... is difficult to recognize, for example, as often happens with QTLs, it is recommended to work with ...
... is difficult to recognize, for example, as often happens with QTLs, it is recommended to work with ...
Creutzfeldt-Jakob Disease - Alzheimer Society of Canada
... to protect a person from getting sporadic or familial CJD. However, certain factors may increase one's risk: Pituitary hormone treatment: ...
... to protect a person from getting sporadic or familial CJD. However, certain factors may increase one's risk: Pituitary hormone treatment: ...
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... The Golgi silver-impregnation method established itself as an important technique for distinguishing morphology at the individual neuron level. This technique has been especially useful for studying human neuroanatomy because it works on postmortem tissue but it is also unreliable and capricious. In ...
... The Golgi silver-impregnation method established itself as an important technique for distinguishing morphology at the individual neuron level. This technique has been especially useful for studying human neuroanatomy because it works on postmortem tissue but it is also unreliable and capricious. In ...
Creativity and emotion: Reformulating the Romantic theory of art
... According to Lewis and Granic (1999), intentional states self-organize through the interaction of cognition and emotion. An initial appraisal triggers and constrains preliminary emotional activation. This emotional activation simultaneously directs and constrains cognitive activity involved in appra ...
... According to Lewis and Granic (1999), intentional states self-organize through the interaction of cognition and emotion. An initial appraisal triggers and constrains preliminary emotional activation. This emotional activation simultaneously directs and constrains cognitive activity involved in appra ...
Disrupted small-world networks in schizophrenia
... The human brain has been described as a large, sparse, complex network characterized by efficient small-world properties, which assure that the brain generates and integrates information with high efficiency. Many previous neuroimaging studies have provided consistent evidence of ‘dysfunctional conn ...
... The human brain has been described as a large, sparse, complex network characterized by efficient small-world properties, which assure that the brain generates and integrates information with high efficiency. Many previous neuroimaging studies have provided consistent evidence of ‘dysfunctional conn ...
Columbia`s psychology
... anxiety disorders (1) and resemble the arousal and avoidance responses shown by normal subjects to conditioned fear cues (2). Thus, a common element of anxiety disorders may be an abnormally elevated fear response. Based on animal models of fear learning (3, 4), this hypothesis leads to the predicti ...
... anxiety disorders (1) and resemble the arousal and avoidance responses shown by normal subjects to conditioned fear cues (2). Thus, a common element of anxiety disorders may be an abnormally elevated fear response. Based on animal models of fear learning (3, 4), this hypothesis leads to the predicti ...
Evolution of Patterning Systems and Circuit Elements for Locomotion
... Subtypes of neurons within a class are more loosely defined, but often express different sets of transcription factors, establish connections that are distinct from other subtypes, and can be morphologically distinct. In terms of evolutionary changes, neuronal classes are often present throughout an ...
... Subtypes of neurons within a class are more loosely defined, but often express different sets of transcription factors, establish connections that are distinct from other subtypes, and can be morphologically distinct. In terms of evolutionary changes, neuronal classes are often present throughout an ...
Brain Abnormalities in Murderers Indicated by
... anatomical subdivisions of each identified stereotactically (Buchsbaum et al 1989). This technique has been used by at least nine different PET groups, and a review of its advantages for facilitating intrasubject and intersubject differences may be found in Harris et al (1991). Absolute glucose valu ...
... anatomical subdivisions of each identified stereotactically (Buchsbaum et al 1989). This technique has been used by at least nine different PET groups, and a review of its advantages for facilitating intrasubject and intersubject differences may be found in Harris et al (1991). Absolute glucose valu ...
To clone or not to clone plant QTLs
... upon the heritability of the trait considered. Under such conditions, the QTL is considered Mendelized [13], and cM distances between a QTL and the nearby molecular markers can be estimated more precisely. Beginning with the same population in which primary mapping was carried out, QTL-NILs can be p ...
... upon the heritability of the trait considered. Under such conditions, the QTL is considered Mendelized [13], and cM distances between a QTL and the nearby molecular markers can be estimated more precisely. Beginning with the same population in which primary mapping was carried out, QTL-NILs can be p ...
2.1 central nervous system: neurotransmission and
... of the atypical neuroleptics possess D3 and D4 antagonistic activity, but their exact role in schizophrenia is not yet fully established. Norepinephrine and Epinephrine: Norepinephrine is a neurotransmitter of brainstem neurons within locus cerulus (pons and neurons of reticular formation) with proj ...
... of the atypical neuroleptics possess D3 and D4 antagonistic activity, but their exact role in schizophrenia is not yet fully established. Norepinephrine and Epinephrine: Norepinephrine is a neurotransmitter of brainstem neurons within locus cerulus (pons and neurons of reticular formation) with proj ...
Jukic et al. SUPPLEMANTARY SUPLEMENTARY METHODS En1+/
... 5HT neurons projecting to the spinal cord, are less likely to be involved in these disorders. 4. Since En1+/Otx2 mutants exhibit alterations in the specification of monoaminergic neurons rather than in their migration or projection (Brodski, et al 2003), only studies that report this aspect of devel ...
... 5HT neurons projecting to the spinal cord, are less likely to be involved in these disorders. 4. Since En1+/Otx2 mutants exhibit alterations in the specification of monoaminergic neurons rather than in their migration or projection (Brodski, et al 2003), only studies that report this aspect of devel ...
n–3 long-chain polyunsaturated fatty acids for optimal function
... preterm and term babies is associated with retinal electrical responses to light stimuli, and to brain cortex related visual acuity maturation, that are similar to those observed in human milk fed infants. Our follow up results in young children suggest that neurodevelopment and cognitive abilities ...
... preterm and term babies is associated with retinal electrical responses to light stimuli, and to brain cortex related visual acuity maturation, that are similar to those observed in human milk fed infants. Our follow up results in young children suggest that neurodevelopment and cognitive abilities ...
Cortical activation and synchronization during sentence
... activation between cortical areas. The theoretical rationale for this focus is that it is becoming clear that thinking is an emergent property of a large-scale network of collaborating cortical areas. Thus, to characterize neural functioning in autism, it may be necessary to examine the cortical act ...
... activation between cortical areas. The theoretical rationale for this focus is that it is becoming clear that thinking is an emergent property of a large-scale network of collaborating cortical areas. Thus, to characterize neural functioning in autism, it may be necessary to examine the cortical act ...
Selkoe (Nat Cell Biol
... apolipoprotein E39 — it becomes clear that this is not the case. Most of the disease-causing missense mutations in APP are clustered at, or adjacent to, the β- or γ-secretase cleavage sites (Fig. 2). These increase Aβ42 production roughly twofold or so, as has been shown in transfected cells, transg ...
... apolipoprotein E39 — it becomes clear that this is not the case. Most of the disease-causing missense mutations in APP are clustered at, or adjacent to, the β- or γ-secretase cleavage sites (Fig. 2). These increase Aβ42 production roughly twofold or so, as has been shown in transfected cells, transg ...
Echokinetic yawning, theory of mind, and empathy
... thus appear to be susceptible to echokinetic yawning in the same way humans are. Although the existence of a TOM in chimpanzees remains controversial (10), the observation of echokinetic yawning in this species argues in favour of different levels of TOM, which are perhaps secondary to the different ...
... thus appear to be susceptible to echokinetic yawning in the same way humans are. Although the existence of a TOM in chimpanzees remains controversial (10), the observation of echokinetic yawning in this species argues in favour of different levels of TOM, which are perhaps secondary to the different ...
How do Migraines Happen
... Hospital, was that migraine pain stems from the dilation and stretching of brain blood vessels, leading to the activation of pain-signaling neurons. Wolff thought the headache was preceded by a drop in blood flow brought about by the constriction of these same blood vessels. Fresh observations from ...
... Hospital, was that migraine pain stems from the dilation and stretching of brain blood vessels, leading to the activation of pain-signaling neurons. Wolff thought the headache was preceded by a drop in blood flow brought about by the constriction of these same blood vessels. Fresh observations from ...
Document
... It was hoped that Parkinson’s might be alleviated by replacing the chemical. It was thought that the tremors of Parkinson’s disease resulted from the death of nerve cells that produced dopamine, and thus the affliction became the first illness attributed to neurotransmitter deficiency. Dr. Carolyn R ...
... It was hoped that Parkinson’s might be alleviated by replacing the chemical. It was thought that the tremors of Parkinson’s disease resulted from the death of nerve cells that produced dopamine, and thus the affliction became the first illness attributed to neurotransmitter deficiency. Dr. Carolyn R ...
Full Text - G3: Genes | Genomes | Genetics
... the 472-Mb genome). A total of 91.3% of gene space is located in the genome sequence (Sato et al. 2008). The genome sequences of the chloroplast (150,519 bp) and mitochondrion (380,861 bp) also have been assembled, by Kato et al. (2000) and Kazakoff et al. (2012), respectively. Numerous bioinformati ...
... the 472-Mb genome). A total of 91.3% of gene space is located in the genome sequence (Sato et al. 2008). The genome sequences of the chloroplast (150,519 bp) and mitochondrion (380,861 bp) also have been assembled, by Kato et al. (2000) and Kazakoff et al. (2012), respectively. Numerous bioinformati ...
Neuron the Memory Unit of the Brain
... Neuron the Memory Unit of the Brain Memory is our ability to encode, store, retain and subsequently recall information and past experiences in the human brain. It is the sum total of what we remember, and gives us the capability to learn and adapt from previous experiences as well as to build relat ...
... Neuron the Memory Unit of the Brain Memory is our ability to encode, store, retain and subsequently recall information and past experiences in the human brain. It is the sum total of what we remember, and gives us the capability to learn and adapt from previous experiences as well as to build relat ...