Studying the topological organization of the cerebral blood flow
... The first network-based study resting on CBF was developed by Friston et al. (1993) using PET imaging. In this paper the distributed brain systems associated with performance of a verbal fluency task were identified through recursive Principal Component Analysis (rPCA) methodology. rPCA method groups b ...
... The first network-based study resting on CBF was developed by Friston et al. (1993) using PET imaging. In this paper the distributed brain systems associated with performance of a verbal fluency task were identified through recursive Principal Component Analysis (rPCA) methodology. rPCA method groups b ...
Berman - LIFE at UCF - University of Central Florida
... or more cognitive domains (complex attention, executive function, learning and memory, language, perceptual-motor, or social cognition) based on: 1. Concern of the individual, a knowledgeable informant, or the clinician that there has been a significant decline in cognitive function; and 2. A substa ...
... or more cognitive domains (complex attention, executive function, learning and memory, language, perceptual-motor, or social cognition) based on: 1. Concern of the individual, a knowledgeable informant, or the clinician that there has been a significant decline in cognitive function; and 2. A substa ...
PDF
... views portray both medial anterior and posterior DMN nodes, but extending, as well, to the cuneus. The lateral views include high values in both left/right lateral–parietal nodes of the DMN, in the superior temporal gyri (including the primary auditory cortices), in the lateral frontal cortex (speci ...
... views portray both medial anterior and posterior DMN nodes, but extending, as well, to the cuneus. The lateral views include high values in both left/right lateral–parietal nodes of the DMN, in the superior temporal gyri (including the primary auditory cortices), in the lateral frontal cortex (speci ...
Association mapping
... - Imputation-based GWAS: imputed SNPs where there was missing data (using known haplotypes and human HapMap3 reference data) - Identified 25,075 SNPs that were significantly associated with IBD (p < 0.01) … collapsed these into 163 IBD-associated loci * 71 of these are new, due to increased statisti ...
... - Imputation-based GWAS: imputed SNPs where there was missing data (using known haplotypes and human HapMap3 reference data) - Identified 25,075 SNPs that were significantly associated with IBD (p < 0.01) … collapsed these into 163 IBD-associated loci * 71 of these are new, due to increased statisti ...
A novel seven-octapeptide repeat insertion in the prion protein
... disease (CJD), Gerstmann–Sträussler–Scheinker (GSS) disease and fatal familial insomnia (FFI) [6]. The clinical phenotype in classical GSS disease is characterized by a progressive cerebellar syndrome, accompanied by extrapyramidal and pyramidal signs and cognitive decline, which may evolve into se ...
... disease (CJD), Gerstmann–Sträussler–Scheinker (GSS) disease and fatal familial insomnia (FFI) [6]. The clinical phenotype in classical GSS disease is characterized by a progressive cerebellar syndrome, accompanied by extrapyramidal and pyramidal signs and cognitive decline, which may evolve into se ...
Hands-on Tutorial to Genome-Wide Association Studies (GWAS), GMI
... proportion of the heritability for human height. Nat Genet. • Yang, J., et al. (2011) Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet. • Deary, I. J., et al. (2012). Genetic contributions to stability and change in intelligence from childhood to old age. Natu ...
... proportion of the heritability for human height. Nat Genet. • Yang, J., et al. (2011) Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet. • Deary, I. J., et al. (2012). Genetic contributions to stability and change in intelligence from childhood to old age. Natu ...
The Brain Tools of Behavioral Neuroscience
... syndromes, the left side of the model is almost completely ignored. ...
... syndromes, the left side of the model is almost completely ignored. ...
Brain transcriptomes of harbor seals demonstrate gene
... response of the host during disease events. For example, using transcriptomic analysis, scientists were able to determine that a toxin caused a mass mortality event of abalone, pinpoint the origin of the toxin, and access the genetic effects on the abalone population (De Wit et al., 2014). However, ...
... response of the host during disease events. For example, using transcriptomic analysis, scientists were able to determine that a toxin caused a mass mortality event of abalone, pinpoint the origin of the toxin, and access the genetic effects on the abalone population (De Wit et al., 2014). However, ...
Mapping eQTL networks with mixed graphical models Inma Tur Mong ´ e
... from many biological systems, including human. In the next few years, we will probably witness the completion of those lists for many model organisms and diseases. One of the next challenges in biology will be to understand how all these molecular components work together to implement the regulatory ...
... from many biological systems, including human. In the next few years, we will probably witness the completion of those lists for many model organisms and diseases. One of the next challenges in biology will be to understand how all these molecular components work together to implement the regulatory ...
Identifying Hallmarks of Consciousness in Non-Mammalian
... From a gross anatomical perspective, avian brains are distinguished from those of mammals by the division of the telencephalon into structures resembling nuclei which lack the laminated cortical mantle characteristic of mammalian brains. Additionally, the avian optic tectum and cerebellum are more e ...
... From a gross anatomical perspective, avian brains are distinguished from those of mammals by the division of the telencephalon into structures resembling nuclei which lack the laminated cortical mantle characteristic of mammalian brains. Additionally, the avian optic tectum and cerebellum are more e ...
Temporary inhibition of AMPA receptors induces a prolonged improvement
... 2005) and accordingly, the mechanism of how CLN3 mutations lead to selective neurodegeneration remains elusive. The disease begins between five and eight years of age, with typical clinical symptoms being progressive vision loss, frequent occurrence of seizures, loss of motor skills and progressive c ...
... 2005) and accordingly, the mechanism of how CLN3 mutations lead to selective neurodegeneration remains elusive. The disease begins between five and eight years of age, with typical clinical symptoms being progressive vision loss, frequent occurrence of seizures, loss of motor skills and progressive c ...
Contributions and challenges for network models in cognitive
... network hubs and network communities. Building on the importance of anatomical and functional interactions, network models have provided insight into the basic structures and mechanisms that enable integrative neural processes. Network models have also been instrumental in understanding the role of ...
... network hubs and network communities. Building on the importance of anatomical and functional interactions, network models have provided insight into the basic structures and mechanisms that enable integrative neural processes. Network models have also been instrumental in understanding the role of ...
Epistatic networks jointly influence phenotypes related to
... of genetic interactions influencing complex traits through differential gene expression. ...
... of genetic interactions influencing complex traits through differential gene expression. ...
Chapter 15 Viral Vector-Based Techniques for Optogenetic
... expression pattern can be achieved by choosing the appropriate viral vector and injection volume. For example, AAV2 injection results in expression patterns that are more localized compared with the pseudotyped AAV2/5, AAV2/8, or AAV2/9. AAV2 is therefore well suited for local expression in volumes ...
... expression pattern can be achieved by choosing the appropriate viral vector and injection volume. For example, AAV2 injection results in expression patterns that are more localized compared with the pseudotyped AAV2/5, AAV2/8, or AAV2/9. AAV2 is therefore well suited for local expression in volumes ...
Braingate Systems.ppt
... of firing of C and AP fibers, the firing of the nonnociceptive fiber may inhibit the firing of the projection neuron and the transmission of pain stimuliGate control theory thus explains how stimulus that activates only nonnociceptive nerves can inhibit pain. The pain seems to be lessened when the a ...
... of firing of C and AP fibers, the firing of the nonnociceptive fiber may inhibit the firing of the projection neuron and the transmission of pain stimuliGate control theory thus explains how stimulus that activates only nonnociceptive nerves can inhibit pain. The pain seems to be lessened when the a ...
Introducing a New Product - V
... produces biochemical reactions in the brain, which match a feeling in the body. When you think happy, inspiring, or positive thoughts, our brain manufactures chemicals that make us feel joyful, inspired, or uplifted. For example, when we look forward to a pleasurable experience, the brain immediatel ...
... produces biochemical reactions in the brain, which match a feeling in the body. When you think happy, inspiring, or positive thoughts, our brain manufactures chemicals that make us feel joyful, inspired, or uplifted. For example, when we look forward to a pleasurable experience, the brain immediatel ...
Linkage disequilibrium mapping of complex disease: fantasy or
... in which certain cluantitative phenotypes are also known to he risk factors for a common disease phenotype. for example, high serum cholesterol is a phenotypic risk factor for coronary heart disease. In this model, genetic and environmental factors may influence the quantitative phenotype more direc ...
... in which certain cluantitative phenotypes are also known to he risk factors for a common disease phenotype. for example, high serum cholesterol is a phenotypic risk factor for coronary heart disease. In this model, genetic and environmental factors may influence the quantitative phenotype more direc ...
Avian brains and a new understanding of
... human brain to represent avian and mammalian species. In this view, the songbird cerebrum covers the thalamus; the human cerebrum covers the thalamus and midbrain. Inset (left) next to the human brain is the zebra finch brain to the same scale. Human brain image reproduced, with permission, courtesy ...
... human brain to represent avian and mammalian species. In this view, the songbird cerebrum covers the thalamus; the human cerebrum covers the thalamus and midbrain. Inset (left) next to the human brain is the zebra finch brain to the same scale. Human brain image reproduced, with permission, courtesy ...
Chapter 07: The Structure of the Nervous System
... Gross Organization of the Mammalian Nervous System Magnetic Resonance Imaging (MRI) Advantages of MRI over CT More detail Does not require X-irradiation Brain slice image in any angle Uses information on how hydrogen atoms respond in the brain to perturbations of a strong magnetic field – signals m ...
... Gross Organization of the Mammalian Nervous System Magnetic Resonance Imaging (MRI) Advantages of MRI over CT More detail Does not require X-irradiation Brain slice image in any angle Uses information on how hydrogen atoms respond in the brain to perturbations of a strong magnetic field – signals m ...
GENETIC MECH.Epilepsy2005 - University of Colorado Denver
... pathogenic mechanisms. In the following sections, some of the idiopathic epilepsies that are caused by mutated ion channels will be discussed in more detail. Familial nocturnal frontal lobe epilepsy. Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a rare partial epilepsy that is chara ...
... pathogenic mechanisms. In the following sections, some of the idiopathic epilepsies that are caused by mutated ion channels will be discussed in more detail. Familial nocturnal frontal lobe epilepsy. Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a rare partial epilepsy that is chara ...
Chaper 1. A Brief History of Cognitive Neuroscience
... were a single unit, whereas Cajal saw each neuron as the independent unit. ...
... were a single unit, whereas Cajal saw each neuron as the independent unit. ...
Action potential - Scranton Prep Biology
... 28.5 The action potential propagates itself along the axon The frequency of action potentials (but not their strength) changes with the strength of the stimulus. ...
... 28.5 The action potential propagates itself along the axon The frequency of action potentials (but not their strength) changes with the strength of the stimulus. ...
Brain Tumor Classification Using Wavelet and Texture
... Tomography (CT), Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI). Compared to all other imaging techniques, MRI is efficient in the application of brain tumor detection and identification, due to the high contrast of soft tissues, high spatial resolution and since it does not ...
... Tomography (CT), Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI). Compared to all other imaging techniques, MRI is efficient in the application of brain tumor detection and identification, due to the high contrast of soft tissues, high spatial resolution and since it does not ...
house symposium 2015 - Instituto do Cérebro
... Animals respond differently to stress. While some individuals are able to overcome the stressor (resilience), others may develop depression or post- traumatic stress disorder. Several lines of evidence suggest a link between behavioral phenotype and long-term plasticity in the classic brain reward c ...
... Animals respond differently to stress. While some individuals are able to overcome the stressor (resilience), others may develop depression or post- traumatic stress disorder. Several lines of evidence suggest a link between behavioral phenotype and long-term plasticity in the classic brain reward c ...
Chromosomal Location of a Recessive Red
... autosomes combined with the sex determination system XY and XX in males and females, respectively) [1]. Among the few visible mutations in the BPH, eye color is one of the mutations that are regularly observed in laboratories [2] [3]. In Delphacidae, red-eyed mutants were reported in the small brown ...
... autosomes combined with the sex determination system XY and XX in males and females, respectively) [1]. Among the few visible mutations in the BPH, eye color is one of the mutations that are regularly observed in laboratories [2] [3]. In Delphacidae, red-eyed mutants were reported in the small brown ...