MOLECULAR CHARACTERISATION OF EXTENDED SPECTRUM BETA LACTAMASE Original Article
... enzymes, and these enzymes are most often found in E. coli, K. pneumoniae and Actenobacter baumannii. This results from point mutation in bla TEM and bla SHV genes due to single amino acid changes Gly238 → Ser, Glu 240→Lys, Arg 164→ser, Arg164→His, Asp179→Asp and Glu (Asp) 104→Lys which has formed t ...
... enzymes, and these enzymes are most often found in E. coli, K. pneumoniae and Actenobacter baumannii. This results from point mutation in bla TEM and bla SHV genes due to single amino acid changes Gly238 → Ser, Glu 240→Lys, Arg 164→ser, Arg164→His, Asp179→Asp and Glu (Asp) 104→Lys which has formed t ...
IOSR Journal of Dental and Medical Sciences (IOSRJDMS)
... Porphyromonas gingivalis that invades easily into blood circulation is associated with the need to obtain nutrients. The component nutrients that are absolutely necessary as iron source are peptides and hemin. Because the main source of hemin is found in the blood hemoglobin, P. gingivalis tends to ...
... Porphyromonas gingivalis that invades easily into blood circulation is associated with the need to obtain nutrients. The component nutrients that are absolutely necessary as iron source are peptides and hemin. Because the main source of hemin is found in the blood hemoglobin, P. gingivalis tends to ...
Lecture-on-Bleeding-disorders-4th-med-3-2
... 1 in 10,000 of the population has the condition called haemophilia A. Clotting factor VIII lacks activity. Another of the clotting ingredients is called factor IX. The activity of this factor is deficient in haemophilia B, also known as Christmas disease. Haemophilia A is approximately five times mo ...
... 1 in 10,000 of the population has the condition called haemophilia A. Clotting factor VIII lacks activity. Another of the clotting ingredients is called factor IX. The activity of this factor is deficient in haemophilia B, also known as Christmas disease. Haemophilia A is approximately five times mo ...
Genetic Influences on Baroreflex Function in Normal Twins
... control of heart rate. Baroreflex control of heart rate is mainly achieved through changes in parasympathetic tone. In contrast, baroreflex control of vascular tone is a function of the sympathetic nervous system.1,13,15 Changes in baroreflex control of heart rate are not always associated with simi ...
... control of heart rate. Baroreflex control of heart rate is mainly achieved through changes in parasympathetic tone. In contrast, baroreflex control of vascular tone is a function of the sympathetic nervous system.1,13,15 Changes in baroreflex control of heart rate are not always associated with simi ...
Hemophilia in the Neonate
... Moderate cases rarely bleed spontaneously but will bleed after surgery or trauma. Severe cases exhibit spontaneous bleeding - w/o any recognizable trauma; - especially joints & muscles. ...
... Moderate cases rarely bleed spontaneously but will bleed after surgery or trauma. Severe cases exhibit spontaneous bleeding - w/o any recognizable trauma; - especially joints & muscles. ...
Antibody Patents in India
... Eg. A mAb or fragment thereof ..binding to one epitope of sH2a (antigen) - A human antibody or antibody fragment directed towards an oxidized fragment of apolipoprotein B whereby the oxidized fragment is IEIGLEGKGFEPTLEALFGK or an epitope thereof. ...
... Eg. A mAb or fragment thereof ..binding to one epitope of sH2a (antigen) - A human antibody or antibody fragment directed towards an oxidized fragment of apolipoprotein B whereby the oxidized fragment is IEIGLEGKGFEPTLEALFGK or an epitope thereof. ...
qualidade do leite cru refrigerado obtido através de ordenha manual
... 18.73 mg/dL, respectively, and no significant difference (p>0.05) in the urea levels among these groups was observed. The CV variation coefficient (VC) was 24.77%. According to Wang et al. (2007), increased urea levels in milk are influenced by metabolizable protein present the diet offered to lacta ...
... 18.73 mg/dL, respectively, and no significant difference (p>0.05) in the urea levels among these groups was observed. The CV variation coefficient (VC) was 24.77%. According to Wang et al. (2007), increased urea levels in milk are influenced by metabolizable protein present the diet offered to lacta ...
Effect of environmental salinity manipulation on
... seawater (125% SW) led to an increase in plasma osmolality (Fig. 1). The plasma osmolality lay very close to the isosmotic line (where plasma osmolality equals SW osmolality). Accumulation of amino acids in hagfish plasma was shown to be both salinity- and amino acid-dependent (two-way ANOVA: salinit ...
... seawater (125% SW) led to an increase in plasma osmolality (Fig. 1). The plasma osmolality lay very close to the isosmotic line (where plasma osmolality equals SW osmolality). Accumulation of amino acids in hagfish plasma was shown to be both salinity- and amino acid-dependent (two-way ANOVA: salinit ...
Jell-O - East Stroudsburg University of Pennsylvania
... of glycine, proline, and hydroxyproline, as well as other amino acids. • Collagen is composed of three polypeptide chains that are wound together into a triple helix and held together by hydrogen bonding. • Gelatin molecules form pockets that trap large amounts of liquid, resulting in a semisolid co ...
... of glycine, proline, and hydroxyproline, as well as other amino acids. • Collagen is composed of three polypeptide chains that are wound together into a triple helix and held together by hydrogen bonding. • Gelatin molecules form pockets that trap large amounts of liquid, resulting in a semisolid co ...
The environmental and genetic evidence for the
... [14]. Hyperlipidemia and hypertension are complex multifactorial and polygenic disorders that are thought to result from an interaction between an individual’s genetic background and various environmental factors. In recent years, a number of studies such as genetic linkage analyses and/or candidate ...
... [14]. Hyperlipidemia and hypertension are complex multifactorial and polygenic disorders that are thought to result from an interaction between an individual’s genetic background and various environmental factors. In recent years, a number of studies such as genetic linkage analyses and/or candidate ...
Bacterial type AB enterotoxins — structure, function and mechanism
... Cholera toxin belongs to type I of the heat-labile enterotoxins and is produced mainly by two serogroups of V. cholerae — O1 and O139 [15]. The subunit A consists of a 22 kDa A1 fragment and 5.4 kDa A2 fragment. The A2 fragment provides an anchor between the A1 and pentameric subunit B. Subunit A1 h ...
... Cholera toxin belongs to type I of the heat-labile enterotoxins and is produced mainly by two serogroups of V. cholerae — O1 and O139 [15]. The subunit A consists of a 22 kDa A1 fragment and 5.4 kDa A2 fragment. The A2 fragment provides an anchor between the A1 and pentameric subunit B. Subunit A1 h ...
Human Blood Lipopolysaccharide-Induced Responses in Serum
... pep27–39, a 13-mer peptide consisting of amino acids 27–39 of SAP, competitively inhibited the binding of LPS to SAP. In addition, pep27–39 significantly inhibited ReLPS-induced responses in phagocytes in the presence of serum, as well as in human whole blood. Carboxamidomethylated pep27–39 showed a ...
... pep27–39, a 13-mer peptide consisting of amino acids 27–39 of SAP, competitively inhibited the binding of LPS to SAP. In addition, pep27–39 significantly inhibited ReLPS-induced responses in phagocytes in the presence of serum, as well as in human whole blood. Carboxamidomethylated pep27–39 showed a ...
13 Recent trends and advances in hemophilia – its management
... surgery. Over the last forty years treatment has advanced so much that the vast majority of patients today are expected to live long and active lives. The main breakthrough in treatment occurred when coagulation factor deficiencies linked to hemophilia could be identified and then replaced, using pr ...
... surgery. Over the last forty years treatment has advanced so much that the vast majority of patients today are expected to live long and active lives. The main breakthrough in treatment occurred when coagulation factor deficiencies linked to hemophilia could be identified and then replaced, using pr ...
factor xii deficiency an inherited bleeding
... Congenital Factor XII deficiency is an inherited coagulation protein deficiency disorder. This means that it is passed on from parent to child at the time of conception. The coagulation protein deficiency is caused by an abnormal gene. Each cell of the body contains structures called “chromosomes.” ...
... Congenital Factor XII deficiency is an inherited coagulation protein deficiency disorder. This means that it is passed on from parent to child at the time of conception. The coagulation protein deficiency is caused by an abnormal gene. Each cell of the body contains structures called “chromosomes.” ...
Functionally conserved cis-regulatory elements of - Genoma
... Ascribing function to non-coding sequence is a primary challenge arising from the sequencing of the human genome (Feingold and Consortium, 2004). Functional non-coding sequences can activate transcription and participate in control of spatiotemporal gene expression and also play a role in diseases ( ...
... Ascribing function to non-coding sequence is a primary challenge arising from the sequencing of the human genome (Feingold and Consortium, 2004). Functional non-coding sequences can activate transcription and participate in control of spatiotemporal gene expression and also play a role in diseases ( ...
Adenosine Diphosphate–Induced Platelet Aggregation
... value for each subject (referred to below as maximal aggregation) for subsequent analyses. The existence of these 2 distinct phenotypic groups of platelet aggregation, together with the stability of ADP responses over time, pointed to possible genetic control of the ADP effect on platelet aggregatio ...
... value for each subject (referred to below as maximal aggregation) for subsequent analyses. The existence of these 2 distinct phenotypic groups of platelet aggregation, together with the stability of ADP responses over time, pointed to possible genetic control of the ADP effect on platelet aggregatio ...
Modifying Starch Biosynthesis with Transgenes in
... from a constitutive promoter (35S). Lines that yielded tubers with no amylose and lines with amounts of amylose intermediate between the wild type and the amf lines were found. This demonstrates part of the power of genetic engineering for starch biosynthesis in that a range of possibly useful pheno ...
... from a constitutive promoter (35S). Lines that yielded tubers with no amylose and lines with amounts of amylose intermediate between the wild type and the amf lines were found. This demonstrates part of the power of genetic engineering for starch biosynthesis in that a range of possibly useful pheno ...
internal organization of the cell
... lipid molecules and their different parts. One can construct a lipid molecule, for example, whose polar head group carries a “spin label,” such as a nitroxyl group ( N–O); this contains an unpaired electron whose spin creates a paramagnetic signal that can be detected by electron spin resonance (ESR ...
... lipid molecules and their different parts. One can construct a lipid molecule, for example, whose polar head group carries a “spin label,” such as a nitroxyl group ( N–O); this contains an unpaired electron whose spin creates a paramagnetic signal that can be detected by electron spin resonance (ESR ...
Preliminary analysis of biologics exclusivity in the leaked Trans
... However this biologic exclusivity would be given to all biologics which meet the biologics definition, without having to pass the patentability criteria of novelty, inventive step and industrial applicability. This means that a biologic medicine that would not be new or inventive enough to deserve a ...
... However this biologic exclusivity would be given to all biologics which meet the biologics definition, without having to pass the patentability criteria of novelty, inventive step and industrial applicability. This means that a biologic medicine that would not be new or inventive enough to deserve a ...
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia.
... This “two disease” model of CLL was further supported by the observation that Ig-unmutated and Ig-mutated CLL patients had distinctly different clinical courses (2, 3). This model predicts that Ig-unmutated and Ig-mutated CLL would not be highly related to each other in gene expression. A precedent ...
... This “two disease” model of CLL was further supported by the observation that Ig-unmutated and Ig-mutated CLL patients had distinctly different clinical courses (2, 3). This model predicts that Ig-unmutated and Ig-mutated CLL would not be highly related to each other in gene expression. A precedent ...
Substrate Binding Modulates the Activity of Mycobacterium
... 35000g for 45 min to remove traces of precipitate, and the sample was loaded onto two-in-tandem 5 mL HisTrap columns equilibrated with buffer A. In this step, His8-MBP and His8TEV remained bound to the column but MbsG did not. The yellow flow-through containing MbsG was pooled and dialyzed for 2 h i ...
... 35000g for 45 min to remove traces of precipitate, and the sample was loaded onto two-in-tandem 5 mL HisTrap columns equilibrated with buffer A. In this step, His8-MBP and His8TEV remained bound to the column but MbsG did not. The yellow flow-through containing MbsG was pooled and dialyzed for 2 h i ...
A Case of Hemophilia A Presenting in a Neonate and a Review of
... In any child with bleeding symptoms, initial evaluation should include a complete blood count, prothrombin time, and activated partial thromboplastin time. Testing factor levels, platelet function, and fibrinogen can also be considered based on the initial lab testing. Consultation with a hematologi ...
... In any child with bleeding symptoms, initial evaluation should include a complete blood count, prothrombin time, and activated partial thromboplastin time. Testing factor levels, platelet function, and fibrinogen can also be considered based on the initial lab testing. Consultation with a hematologi ...
Identification of Genotypes of Blood Group A and B
... two sites, one for A, or not B.’2 Later, the true allelic ...
... two sites, one for A, or not B.’2 Later, the true allelic ...
Functional Foods: Soy Protein
... density. These effects require the soy protein and its isoflavones. The protein and isoflavones appear to act synergistically. This means their effect is greater together than individually. Recent studies have cast doubt on the ability of soy to control hot flashes in postmenopausal women. In a doub ...
... density. These effects require the soy protein and its isoflavones. The protein and isoflavones appear to act synergistically. This means their effect is greater together than individually. Recent studies have cast doubt on the ability of soy to control hot flashes in postmenopausal women. In a doub ...
catalolgue of products
... high bio-available amino acid (Lysine, Histidine and Methionine), low content of growth retarding compounds due to fish freshness and producing low effluent of undigested organic matter, avoiding significant detrimental effect on the environment surrounding the salmon farms. ...
... high bio-available amino acid (Lysine, Histidine and Methionine), low content of growth retarding compounds due to fish freshness and producing low effluent of undigested organic matter, avoiding significant detrimental effect on the environment surrounding the salmon farms. ...
Complement component 4
Complement component 4 is a protein involved in the complement system.It is cleaved into proteins 4a and 4b; 4b can be further cleaved into 4c and 4d. C4a is an anaphylatoxin. C4b forms part of C3-convertase, in conjunction with 2a: C4b can bind CR1.