Ketone Bodies Mimic the Life Span Extending
... high doses of ascorbic acid made by Linus Pauling were largely unsubstantiated. It was through the work of Krebs and Veech that the control of redox states in the cell and the dominant role of the free [NADP1]/[NADPH] was appreciated (38). The detoxification of free radicals is dependent upon the mu ...
... high doses of ascorbic acid made by Linus Pauling were largely unsubstantiated. It was through the work of Krebs and Veech that the control of redox states in the cell and the dominant role of the free [NADP1]/[NADPH] was appreciated (38). The detoxification of free radicals is dependent upon the mu ...
Di-(2-ethylhexyl) phthalate mediates glycolysis and the TCA cycle
... bio-accumulated levels of DEHP in clam Venerupis philippinarum. After exposure to 0.4 mg L-1 and 4mg L-1 DEHP, the bio-accumulated DEHP in the clam foot was significantly increased in the first 24 h, and then sharply decreased from 0.203 ± 0.022 μg g-1 to 0.104 ± 0.011 μg g-1 , and from 1.689 ± 0.01 ...
... bio-accumulated levels of DEHP in clam Venerupis philippinarum. After exposure to 0.4 mg L-1 and 4mg L-1 DEHP, the bio-accumulated DEHP in the clam foot was significantly increased in the first 24 h, and then sharply decreased from 0.203 ± 0.022 μg g-1 to 0.104 ± 0.011 μg g-1 , and from 1.689 ± 0.01 ...
mTOR complex 2 (mTORC2) controls hydrophobic motif
... also abolished in rictor-, Sin1- or mLST8-deficient fibroblasts. mTORC2 immunoprecipitated from wild-type, but not from mLST8- or rictor-knockout cells, phosphorylated SGK1 at Ser422 . Consistent with mTORC1 not regulating SGK1, immunoprecipitated mTORC1 failed to phosphorylate SGK1 at Ser422 , unde ...
... also abolished in rictor-, Sin1- or mLST8-deficient fibroblasts. mTORC2 immunoprecipitated from wild-type, but not from mLST8- or rictor-knockout cells, phosphorylated SGK1 at Ser422 . Consistent with mTORC1 not regulating SGK1, immunoprecipitated mTORC1 failed to phosphorylate SGK1 at Ser422 , unde ...
1 - Plant Research International
... Cysteine synthesis is essential for growth and metabolism. It links carbon and nitrogen metabolism and is a central precursor for all biological compounds that contain reduced sulfur (Hofgen et al., 2001) including CSOs. Synthesis occurs in green and nongreen tissues (Barroso et al., 1998) in two se ...
... Cysteine synthesis is essential for growth and metabolism. It links carbon and nitrogen metabolism and is a central precursor for all biological compounds that contain reduced sulfur (Hofgen et al., 2001) including CSOs. Synthesis occurs in green and nongreen tissues (Barroso et al., 1998) in two se ...
UNIT 11. CATABOLISM OF GLUCOSE • Aerobic glycolysis: scheme
... Glycolysis is an oxidative specific pathway by which one mole of glucose is enzymatically split into two moles of pyruvate. It occurs in cytosol of all cells of the body. The principle function of glycolysis is the generation of ATP. Glycolysis also provides precursors for fatty acids biosynthesis, ...
... Glycolysis is an oxidative specific pathway by which one mole of glucose is enzymatically split into two moles of pyruvate. It occurs in cytosol of all cells of the body. The principle function of glycolysis is the generation of ATP. Glycolysis also provides precursors for fatty acids biosynthesis, ...
Embden-Meyerhof-Parnas Pathway
... • Thus, controlling a metabolic flux is not normally achieved by ...
... • Thus, controlling a metabolic flux is not normally achieved by ...
Fastness in Mycobacterium tuberculosis
... have shown that most essential enzymes forming the central core of type II fatty acid synthase (FASII) are phosphorylated by STPK [6] and that, at least in vitro, post-translational phosphorylation inhibits the activity of these enzymes. These include the b-ketoacyl ACP synthase KasA, the b-ketoacyl ...
... have shown that most essential enzymes forming the central core of type II fatty acid synthase (FASII) are phosphorylated by STPK [6] and that, at least in vitro, post-translational phosphorylation inhibits the activity of these enzymes. These include the b-ketoacyl ACP synthase KasA, the b-ketoacyl ...
Biochemistry Lecture 15
... – Inhib'n when ↑[acetyl-CoA] • Prod of further metab • Serves as feedback inhibitor • May be formed when fats catabolized, when glycolysis not needed ...
... – Inhib'n when ↑[acetyl-CoA] • Prod of further metab • Serves as feedback inhibitor • May be formed when fats catabolized, when glycolysis not needed ...
Substitutions and Deletions in the Cytoplasmic
... phagocytic function, we constructed a mutant FcyRIIA (A287-291) in which 5 amino acids including the two prolines were deleted from this sequence (Fig 1). This mutant contains a 7 amino acid proline-free region between the two Y-x-x-L sequences and is thus similar to the consensus sequence of other ...
... phagocytic function, we constructed a mutant FcyRIIA (A287-291) in which 5 amino acids including the two prolines were deleted from this sequence (Fig 1). This mutant contains a 7 amino acid proline-free region between the two Y-x-x-L sequences and is thus similar to the consensus sequence of other ...
Cardiac mitochondrial matrix and respiratory complex - AJP
... cytosolic ADP with matrix ATP generated by oxidative phosphorylation (109). Phosphorylation sites have been found in all of the isoforms of ANT by numerous investigators. These sites include, in ANT-1, Ser7 (24, 236), Ser22 (24, 236), Tyr81 (24), Thr84 (24), Tyr191 (236), and Tyr195 (24, 67); in ANT ...
... cytosolic ADP with matrix ATP generated by oxidative phosphorylation (109). Phosphorylation sites have been found in all of the isoforms of ANT by numerous investigators. These sites include, in ANT-1, Ser7 (24, 236), Ser22 (24, 236), Tyr81 (24), Thr84 (24), Tyr191 (236), and Tyr195 (24, 67); in ANT ...
Article Lateral Gene Transfer and Gene
... Specifically, modifications of energy metabolism in anaerobic forms of mitochondria (e.g., hydrogenosomes) are likely to have been associated with gene transfer from prokaryotes. An interesting question is whether the products of transferred genes were directly targeted into the ancestral organelle ...
... Specifically, modifications of energy metabolism in anaerobic forms of mitochondria (e.g., hydrogenosomes) are likely to have been associated with gene transfer from prokaryotes. An interesting question is whether the products of transferred genes were directly targeted into the ancestral organelle ...
as a PDF - CiteSeerX
... species were detected as two bands; one of them had the same molecular weight as the authentic pepsin and the other hand a molecular weight intermediate between those of pepsinogen and pepsin. The intermediate form was relatively stable as compared with pepsinogen, but was gradually converted to pep ...
... species were detected as two bands; one of them had the same molecular weight as the authentic pepsin and the other hand a molecular weight intermediate between those of pepsinogen and pepsin. The intermediate form was relatively stable as compared with pepsinogen, but was gradually converted to pep ...
MUC1 in the kidney - University of Pittsburgh
... MUC1 is a transmembrane glycoprotein with an extracellular mucin-like domain that yields protection from pathogens ...
... MUC1 is a transmembrane glycoprotein with an extracellular mucin-like domain that yields protection from pathogens ...
Requires Rubisco
... Destruction of RXN CTR occurs by side reactions of the Chla+. The P680+. (reaction center of photosystem II) is strongly oxidizing RXN CTR proteins are oxidatively damaged by Chla +. At high hv intensity, RXN CTR proteins turn over rapidly ...
... Destruction of RXN CTR occurs by side reactions of the Chla+. The P680+. (reaction center of photosystem II) is strongly oxidizing RXN CTR proteins are oxidatively damaged by Chla +. At high hv intensity, RXN CTR proteins turn over rapidly ...
The Proteins of the Keratin Component of Bird`s Beaks
... these proteins show an overall similarity in composition. This is particularly evident in their contents of glycine (about 30 residues %), tyrosine, serine and proline which together account for 55-60 % of the total residues. Their content of half-cystine, determined as S-carboxymethyl cysteine, is ...
... these proteins show an overall similarity in composition. This is particularly evident in their contents of glycine (about 30 residues %), tyrosine, serine and proline which together account for 55-60 % of the total residues. Their content of half-cystine, determined as S-carboxymethyl cysteine, is ...
Protein Posttranslational Modifications: The Chemistry of Proteome
... rium Pseudomonas aeruginosa exhibits more than 60 such pathways.[6] The enzymes dedicated to protein phosphorylation are among the largest class of PTM enzymes. This superfamily of protein kinases have been termed the kinome, with over 500 members in the human kinome.[7] If these acted on average on ...
... rium Pseudomonas aeruginosa exhibits more than 60 such pathways.[6] The enzymes dedicated to protein phosphorylation are among the largest class of PTM enzymes. This superfamily of protein kinases have been termed the kinome, with over 500 members in the human kinome.[7] If these acted on average on ...
Krogh, A., Brown, M., Mian, I.S., Sjolander, K., and Haussler, D. Hidden Markov Models in Computational Biology. J. Mol. Biol. , 235. pp. 1501-1531, 1994.
... There is no known efficientway to directly calculate the extra amino acids between consecutive positions; and (c) YL or MAP sense, best HMM model eitherinthe allowing For the possibility that continuing an insertion or However. there are algorithms that given an arbitrary deletion is morelikely than ...
... There is no known efficientway to directly calculate the extra amino acids between consecutive positions; and (c) YL or MAP sense, best HMM model eitherinthe allowing For the possibility that continuing an insertion or However. there are algorithms that given an arbitrary deletion is morelikely than ...
Dominant-Negative Receptor Uncovers
... plants may somehow monitor and balance the activity of cell division and cell expansion to retain a stable organ size. Therefore, revealing the mechanisms that coordinate these two processes at the supracellular level is critical for a better understanding of plant growth and development. The molecu ...
... plants may somehow monitor and balance the activity of cell division and cell expansion to retain a stable organ size. Therefore, revealing the mechanisms that coordinate these two processes at the supracellular level is critical for a better understanding of plant growth and development. The molecu ...
Lecture 12-14 (Parker) - Department of Chemistry ::: CALTECH
... In 1897 Hans and Eduard Buchner discovered that yeast extracts could rapidly ferment sucrose into alcohol. Startling discovery in its day because it was widely held that fermentation was a process that occurs within cells. This led to efforts to understand the mechanism of this extracellular fermen ...
... In 1897 Hans and Eduard Buchner discovered that yeast extracts could rapidly ferment sucrose into alcohol. Startling discovery in its day because it was widely held that fermentation was a process that occurs within cells. This led to efforts to understand the mechanism of this extracellular fermen ...
chapter_14_respiration_in_plants
... F0and F1components. The F1headpiece is a peripheral membrane protein complex and contains the site for ATP synthesis from ADP and inorganic phosphate. F0component is a part of membrane protein complex, which acts as a channel for crossing of the protons from inner mitochondrial membrane to the mitoc ...
... F0and F1components. The F1headpiece is a peripheral membrane protein complex and contains the site for ATP synthesis from ADP and inorganic phosphate. F0component is a part of membrane protein complex, which acts as a channel for crossing of the protons from inner mitochondrial membrane to the mitoc ...
Origins and Evolution of Pathways of Anaerobic Metabolism in the
... metabolic activity (multiple opine pathways and lactate pathway). The aspartate-succinate and opine pathways require both amino acids and carbohydrate as substrates, whereas the glucose-succinate and lactate pathways are dependent on carbohydrate only. Phylogenetic, functional and chemical considera ...
... metabolic activity (multiple opine pathways and lactate pathway). The aspartate-succinate and opine pathways require both amino acids and carbohydrate as substrates, whereas the glucose-succinate and lactate pathways are dependent on carbohydrate only. Phylogenetic, functional and chemical considera ...
A. Work Accomplished by You and/or Others Cellular biology of
... and higher eukaryotes. A number of these proteins play dependency on the chaperone for both stability and roles in human cancer. activity even under non-stress conditions, and consequently high levels of Hsp90 are found in all eukaryotic cells. A hallmark of Hsp90-client protein interactions is that ...
... and higher eukaryotes. A number of these proteins play dependency on the chaperone for both stability and roles in human cancer. activity even under non-stress conditions, and consequently high levels of Hsp90 are found in all eukaryotic cells. A hallmark of Hsp90-client protein interactions is that ...