Glycolysis
... Irreversible phosphorylation of glucose by Hexokinase effectively trap glucose as glucose 6-p that can not diffuse out of the cell. Mammals have several isozymes of Hexokinase that catalyze the phosphorylation. isozymes: Enzymes that catalyze the same reaction but are different in their kinetic beha ...
... Irreversible phosphorylation of glucose by Hexokinase effectively trap glucose as glucose 6-p that can not diffuse out of the cell. Mammals have several isozymes of Hexokinase that catalyze the phosphorylation. isozymes: Enzymes that catalyze the same reaction but are different in their kinetic beha ...
Was photosynthetic RuBisCO recruited by
... mutation of these residues leads to a lack of enolization activity [16,19]. B. subtilis RLP conserves all these amino acid residues (Fig. 2). This observation supports the hypothesis that the RLP-catalyzed enolization of DK-MTP-1-P does not require the amino acid residues for binding the phosphate g ...
... mutation of these residues leads to a lack of enolization activity [16,19]. B. subtilis RLP conserves all these amino acid residues (Fig. 2). This observation supports the hypothesis that the RLP-catalyzed enolization of DK-MTP-1-P does not require the amino acid residues for binding the phosphate g ...
biochemical investigation into initiation of fatty acid synthesis in the
... parasite T. brucei. In my dissertation, I addressed various aspects of the regulation of TbACC, which catalyzes the first committed step in FA synthesis. In the second chapter, I hypothesized that TbACC is regulated in response to environmental lipids. I examined changes in TbACC RNA, protein abunda ...
... parasite T. brucei. In my dissertation, I addressed various aspects of the regulation of TbACC, which catalyzes the first committed step in FA synthesis. In the second chapter, I hypothesized that TbACC is regulated in response to environmental lipids. I examined changes in TbACC RNA, protein abunda ...
Cloning of adiponectin receptors that mediate antidiabetic metabolic
... data indicated that AdipoR1 and AdipoR2 are able to mediate the binding of globular and full-length adiponectin, as well as increases in PPAR-a ligand activity and fatty-acid oxidation by globular and full-length adiponectin. C2C12 myocytes transfected with unrelated small-interfering (si)RNA20 boun ...
... data indicated that AdipoR1 and AdipoR2 are able to mediate the binding of globular and full-length adiponectin, as well as increases in PPAR-a ligand activity and fatty-acid oxidation by globular and full-length adiponectin. C2C12 myocytes transfected with unrelated small-interfering (si)RNA20 boun ...
Pyruvate Dehydrogenase
... The outer membrane contains large VDAC channels, similar to bacterial porin channels, making the outer membrane leaky to ions & small molecules. ...
... The outer membrane contains large VDAC channels, similar to bacterial porin channels, making the outer membrane leaky to ions & small molecules. ...
glycolysis
... Thus [F-2,6-bisP] , PFK-1 less Phosphofructokinase-2 active, glycolysis is depressed ...
... Thus [F-2,6-bisP] , PFK-1 less Phosphofructokinase-2 active, glycolysis is depressed ...
Glyphosate pathways to modern diseases V: Amino
... to the nitrogen of glycine, and such units can be assembled into “peptoid” chains that in many ways resemble peptide chains, except that they are highly resistant to proteolysis. This is presumed to be beneficial because it allows the antimicrobial agent to survive longer in the tissues. These autho ...
... to the nitrogen of glycine, and such units can be assembled into “peptoid” chains that in many ways resemble peptide chains, except that they are highly resistant to proteolysis. This is presumed to be beneficial because it allows the antimicrobial agent to survive longer in the tissues. These autho ...
and Rhizobiales-Like PPP-Family Protein Phosphatases from
... elucidate the evolutionary, biochemical, cellular and biological characteristics of two recently identified PPP-family protein phosphatase subclasses from the model photosynthetic Eukaryote Arabidopsis thaliana. These two subclasses included the Shewanella-like (SLP1 and 2) and Rhizobiales-like (RLP ...
... elucidate the evolutionary, biochemical, cellular and biological characteristics of two recently identified PPP-family protein phosphatase subclasses from the model photosynthetic Eukaryote Arabidopsis thaliana. These two subclasses included the Shewanella-like (SLP1 and 2) and Rhizobiales-like (RLP ...
Hypoxia in skeletal muscles: from physiology to gene expression
... patients who suffer from chronic hypoxia [36]. Consistently, Magalhaes et al. report a functional impairment of mitochondrial complex V in skeletal muscles during an acute hypoxia induced by eccentric exercise [12]. A switch of mitochondrial complex IV subunits COX4-1 and COX4-2 is discovered by Fuk ...
... patients who suffer from chronic hypoxia [36]. Consistently, Magalhaes et al. report a functional impairment of mitochondrial complex V in skeletal muscles during an acute hypoxia induced by eccentric exercise [12]. A switch of mitochondrial complex IV subunits COX4-1 and COX4-2 is discovered by Fuk ...
Effect of Ca on H -ATPase activity of plasma membrane in
... pump that directly couples ATP hydrolysis with the vectorial transport of H into the appolast. The electrochemical proton gradient acts as a driving force for the secondary transport of ions and nutrients into and out of cell. It also controls some major physiological-biochemical process, e.g. gro ...
... pump that directly couples ATP hydrolysis with the vectorial transport of H into the appolast. The electrochemical proton gradient acts as a driving force for the secondary transport of ions and nutrients into and out of cell. It also controls some major physiological-biochemical process, e.g. gro ...
Enzymes
... There are two fundamental conditions for life. One, the living entity must be able to self-replicate (a topic considered in Part IV of this book); two, the organism must be able to catalyze chemical reactions efficiently and selectively. The central importance of catalysis may surprise some beginnin ...
... There are two fundamental conditions for life. One, the living entity must be able to self-replicate (a topic considered in Part IV of this book); two, the organism must be able to catalyze chemical reactions efficiently and selectively. The central importance of catalysis may surprise some beginnin ...
biolsci.org - International Journal of Biological Sciences
... KHG20612, Figure 3a) and Bacillus anthracis are documented [9, 10, 25, 26]. ...
... KHG20612, Figure 3a) and Bacillus anthracis are documented [9, 10, 25, 26]. ...
Protein O-linked β-N-acetylglucosamine
... are, a long N100 kDa form, and a short form (~70 kDa) with the OGlcNAcase catalytic regions in the N-terminal domain [6,79]. The Cterminal region of the long isoform has a histone acetyl-transferase like domain with a caspase cleavage site between the two regions suggesting potential regulation in r ...
... are, a long N100 kDa form, and a short form (~70 kDa) with the OGlcNAcase catalytic regions in the N-terminal domain [6,79]. The Cterminal region of the long isoform has a histone acetyl-transferase like domain with a caspase cleavage site between the two regions suggesting potential regulation in r ...
Regulation of Pyruvate Dehydrogenase (PDH
... glycolytic pathway with the production of pyruvate (Fig. 1). One of the major fates of pyruvate is to be transported into the mitochondria where the nonequilibrium enzyme pyruvate dehydrogenase (PDH) regulates the conversion of pyruvate to acetyl-coenzyme A (acetyl-CoA). This reaction regulates the ...
... glycolytic pathway with the production of pyruvate (Fig. 1). One of the major fates of pyruvate is to be transported into the mitochondria where the nonequilibrium enzyme pyruvate dehydrogenase (PDH) regulates the conversion of pyruvate to acetyl-coenzyme A (acetyl-CoA). This reaction regulates the ...
Propionate metabolism in Saccharomyces cerevisiae
... Aerobic, glucose-limited chemostat of Saccharomyces cerevisiae CBS 8066 cometabolized propionate when this compound was added t o the reservoir medium. Co-metabolism of propionate led to an increase of the biomass and protein yields. Attempts to grow 5. cerevisiae on propionate as a sole source of c ...
... Aerobic, glucose-limited chemostat of Saccharomyces cerevisiae CBS 8066 cometabolized propionate when this compound was added t o the reservoir medium. Co-metabolism of propionate led to an increase of the biomass and protein yields. Attempts to grow 5. cerevisiae on propionate as a sole source of c ...
Characterization of NAD Salvage Pathways and their Role in
... primarily responsible for nicotinamide riboside import. Furthermore, a pnuC mutant is ...
... primarily responsible for nicotinamide riboside import. Furthermore, a pnuC mutant is ...
Glucose Regulation by Dr Sarma
... receptor tyrosine kinase Clinical Pearl with the ligand, often a growth factor, up1. Up regulation of TK receptor regulates the enzymatic (autophosphorylation) in obesityactivity of the intra cellular catalytic 2. Leads to Glucose entry into cells with out insulin domain, which causes signal tyrosin ...
... receptor tyrosine kinase Clinical Pearl with the ligand, often a growth factor, up1. Up regulation of TK receptor regulates the enzymatic (autophosphorylation) in obesityactivity of the intra cellular catalytic 2. Leads to Glucose entry into cells with out insulin domain, which causes signal tyrosin ...
Doctorial Thesis Regulation of Branched
... Leucine is an essential branched-chain amino acid and plays a key role in protein synthesis through mammalian target of rapamycin (mTOR). Recently, it has been reported that an oral administration of leucine has been revealed to influence the plasma concentrations of other amino acids not only isole ...
... Leucine is an essential branched-chain amino acid and plays a key role in protein synthesis through mammalian target of rapamycin (mTOR). Recently, it has been reported that an oral administration of leucine has been revealed to influence the plasma concentrations of other amino acids not only isole ...
MPN+, a putative catalytic motif found in a subset of MPN domain
... Background: Three macromolecular assemblages, the lid complex of the proteasome, the COP9Signalosome (CSN) and the eIF3 complex, all consist of multiple proteins harboring MPN and PCI domains. Up to now, no specific function for any of these proteins has been defined, nor has the importance of these ...
... Background: Three macromolecular assemblages, the lid complex of the proteasome, the COP9Signalosome (CSN) and the eIF3 complex, all consist of multiple proteins harboring MPN and PCI domains. Up to now, no specific function for any of these proteins has been defined, nor has the importance of these ...
Enzyme Mechanisms
... Homologous enzymes catalyze related reactions; this is how trp and his biosynthesis enzymes seem to have evolved Variant: recruit some enzymes from another pathway without duplicating the whole thing (example: ubiquitination) ...
... Homologous enzymes catalyze related reactions; this is how trp and his biosynthesis enzymes seem to have evolved Variant: recruit some enzymes from another pathway without duplicating the whole thing (example: ubiquitination) ...
Enzymatic activation of sulfur for incorporation into biomolecules in
... vinelandii is located at the 5 0 end of an operon, which also contains iscU, iscA, hscB, hscA and fdx; this type of operon is widespread in nature (Zheng et al., 1998) and crucial for general iron sulfur cluster (isc) biosynthesis in many organisms. IscU is the scaffold protein interacting with IscS ...
... vinelandii is located at the 5 0 end of an operon, which also contains iscU, iscA, hscB, hscA and fdx; this type of operon is widespread in nature (Zheng et al., 1998) and crucial for general iron sulfur cluster (isc) biosynthesis in many organisms. IscU is the scaffold protein interacting with IscS ...
29 Pathways of Sugar Metabolism: Pentose
... seminal fluid. Spermatozoa use fructose as a major fuel source while in the seminal fluid and then switch to glucose once in the female reproductive tract. Utilization of fructose is thought to prevent acrosomal breakdown of the plasma membrane (and consequent activation) while the spermatozoa are s ...
... seminal fluid. Spermatozoa use fructose as a major fuel source while in the seminal fluid and then switch to glucose once in the female reproductive tract. Utilization of fructose is thought to prevent acrosomal breakdown of the plasma membrane (and consequent activation) while the spermatozoa are s ...
Acetyl CoA - WordPress.com
... double membrane, with an intermembrane space between the two layers. The transition reaction and citric acid cycle occur in the mitochondrial matrix. The electron transport system is located in the cristae of the mitochondria. ...
... double membrane, with an intermembrane space between the two layers. The transition reaction and citric acid cycle occur in the mitochondrial matrix. The electron transport system is located in the cristae of the mitochondria. ...
- Free Documents
... protein, and in the other direction by a protein phosphatase, which removes the phosphate proteins in a third oI the . It is estimated that one A Figure groups Irom the protein eucaryotic cell are phosphorylated at any given time. The other main class oI molecular switches involved in signaling are ...
... protein, and in the other direction by a protein phosphatase, which removes the phosphate proteins in a third oI the . It is estimated that one A Figure groups Irom the protein eucaryotic cell are phosphorylated at any given time. The other main class oI molecular switches involved in signaling are ...
Origin of metabolism
... The chemistry of life is distinguished both by its high degree of order and by its essential dependence on a number of far-from-equilibrium reactions [1]. While in some cases reactions may be treated as isolated subsystems with equilibrium approximations [2, 3], such isolations are themselves cumula ...
... The chemistry of life is distinguished both by its high degree of order and by its essential dependence on a number of far-from-equilibrium reactions [1]. While in some cases reactions may be treated as isolated subsystems with equilibrium approximations [2, 3], such isolations are themselves cumula ...