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... one to two centimeters Typically located over bony surface or near tendon Present for 1-2 weeks but rarely more than a month Least common manifestation (in the US) ...
Chapter 21 – Nutrition and Disorders of the Heart and Blood Vessels
Chapter 21 – Nutrition and Disorders of the Heart and Blood Vessels

... A. Consequences of Congestive Heart Failure B. Medical Management of Congestive Heart Failure 1. Medical Nutrition Therapy 2. Other Dietary Recommendations VI. Stroke A. Stroke Prevention B. Stroke Management VII. Nutrition in Practice – Helping People with Feeding Disabilities A. In what ways can d ...
Chapter 40 Review
Chapter 40 Review

... response? B cells • What types of cells are used in a cell-mediated response? T cells ...
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... People may die of oxygen deprivation Bacterial or viral infection, caused by breathing in infected air ...
Who Gets Lupus?
Who Gets Lupus?

... Complement activation plays a critical role in the inflammatory process and tissue damage in SLE, but early complement deficiencies cause SLE. ...
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... Why, even among family members, a match is difficult to obtain….. ...
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Autoimmune Disease

... Insulin genes transcribed at high level in thymus protect against diabetes ...
Sprains
Sprains

... Rest: Get off your feet – take weight off the affected limb. Ice: Apply an ice bag wrapped in cloth to the affected area for 20 minutes every 2 hours. Don’t apply ice directly to the skin. Compression: Wrap the area in an ace bandage. Elevation: Raise the affected limb to a level above your heart. A ...
Medical and dental relationships: What you may not realize
Medical and dental relationships: What you may not realize

... Periodontal disease is the most chronic infection affecting Americans. Periodontal disease is the most significant disease affecting adults. It’s a chronic bacterial infection that impacts the gums and bone that support teeth, About 80% of Americans currently have some form of periodontal disease. S ...
Lecture 5 - Drugs used in inflammatory bowel disease
Lecture 5 - Drugs used in inflammatory bowel disease

... – Complete blood count & liver function tests are required in all patients ...
Multiple Sclerosis Article
Multiple Sclerosis Article

... Plaque forms when the myelin sheath is destroyed, a process called demyelination. Without the myelin, signals are disrupted or halted. The symptoms and the course of the disease vary widely, partly due to the location of scar tissue and to the extent of demyelination. There is no known cause of MS. ...
Peptic Ulcer Disease
Peptic Ulcer Disease

... Taken with food = last up to 3 hours Adverse effects – Diarrhea – Constipation ...
INFLAMMATION and YOUR HEALTH
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...  Delayed Onset  Up to many months or years  Outcome: ...
The Inflammatory Response
The Inflammatory Response

... ●you feel and see it (pain, redness, swelling, heat). ●Inflammatory cytokines are expressed and do their job and resolution occurs relatively quickly –it’s over and done with. Chronic inflammation (CI): ● macrophages dominate. ●T cells and B cells become involved. ●CI is silent—progresses without on ...
The role of IL-12/IL-23 in Crohn`s disease
The role of IL-12/IL-23 in Crohn`s disease

... large intestine (colon), but may involve any part from the mouth to the anus. 1,2 In Europe 250,000 people are living with Crohn’s disease, with around 18,000 new cases diagnosed each year.3 Though anyone can be affected by Crohn’s disease at any age, it most often impacts those between the ages of ...
V. cholerae M. tuberculosis
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... Substance produced by a microorganism that selectively kills or inhibits the growth of bacteria ...
www.barnsleyvts.co.uk
www.barnsleyvts.co.uk

... atrioventricular canal - the most common ...
Immuno Revision Notes
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... • Normal/increased B cells • Reduced anIbody response • Immunodeficiency can improve with ...
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... Antigen-IgE complexes form on a small scale, and not enough mediator is released to produce a major reaction. This permits the administration of a drug or foreign protein to a hypersensitive person, but ...
The Integrative Management of Neurodegenerative Disorders
The Integrative Management of Neurodegenerative Disorders

... • Because of its availability and low cost, coupled with preclinical data showing its potential for intervention at multiple sites inAD pathogenesis, curcumin is now in clinical trials in mild to moderate AD patients under an FDA approved IND by theUCLA Alzheimer Center • Epidemiology shows risk red ...
Fifth Disease
Fifth Disease

... In children, the infection is usually mild and of short duration. Teenagers and adults may have self-limited arthritis. Older children and adults may have difficulty walking and in bending their joints such as wrists, knees, ankles, fingers and shoulders. It is important that this infection be diagn ...
approach to monoarthritis
approach to monoarthritis

... Enteropathic Arthritis (mainly Crohn’s) Amyloidosis Pigmented villonodular synovitis Synovial pathology (sarcoma, chondromatosis) Monoarticular presentation of oligo- / poly articular disease ...
Combination biologic therapy - Clinical and Experimental
Combination biologic therapy - Clinical and Experimental

... body mass in “RA cachexia” (5, 6). Antagonists of IL-1β plus TNFα are synergistic in streptococcal cell wall and collagen II models of arthritis, but clinical data with this combination are lacking (7-10). Although animal models have suggested relatively specific effects for these proinflammatory cy ...
Ankylosing Spondylitis or Marie-Strumpell Disease
Ankylosing Spondylitis or Marie-Strumpell Disease

... arthritis of the extremities may soon follow. Although the exact cause of the disease remains unknown, an autoimmune process is strongly suspected. This would make it fall into the category of diseases such as: lupus, rheumatoid arthritis, and scleroderma. X-ray or an MRI of the sacroiliac joint usu ...
MR Imaging in Atypical Septic Arthritis of the Knee
MR Imaging in Atypical Septic Arthritis of the Knee

... Typical vs Atypical Septic Arthritis Infectious process of the joint which commonly involves multiple compartments including the synovium, ligaments, tendons, cartilage, bone and surrounding soft tissues ...
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Rheumatoid arthritis



Rheumatoid arthritis (RA) is a long lasting autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly the wrist and hands are involved with typically the same joints involved on both sides of the body. The disease may also affect other parts of the body. This may result in low red blood cells, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often symptoms come on gradually over weeks to months.While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is made mostly on the basis of a person's signs and symptoms. X-rays and laboratory testing may support a diagnosis or exclude other diseases with similar symptoms. Other diseases that may present similarly include systemic lupus erythematosus, psoriatic arthritis, and fibromyalgia among others.The goal of treatment is to improve pain, decrease inflammation, and improve a person's overall functioning. This may be helped by balancing rest and exercise, the use of splints and braces, or the use of assistive devices. Pain medications, steroids, and NSAIDs are frequently used to help with symptoms. A group of medications called disease-modifying antirheumatic drugs (DMARDs) may be used to try to slow the progression of disease. They include the medications hydroxychloroquine and methotrexate. Biological DMARDs may be used when disease does not respond to other treatments. However, they may have a greater rate of adverse effects. Surgery to repair, replace, or fusion joints may help in certain situations. Most alternative medicine treatments are not supported by evidence.RA affects between 0.5 and 1% of adults in the developed world with between 5 and 50 per 100,000 people newly developing the condition each year. Onset is most frequent during middle age and women are affected 2.5 times as frequently as men. In 2013 it resulted in 38,000 deaths up from 28,000 deaths in 1990. The first recognized description of RA was made in 1800 by Dr. Augustin Jacob Landré-Beauvais (1772–1840) of Paris. The term rheumatoid arthritis is based on the Greek for watery and inflamed joints.
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