What is rheumatoid arthritis ?
... • HLA DR4 is the major halo-type in ethnic group, HLA DR1 in Indians and HLA DW15 in Japanese. N.B : • 50-70 % of caucasian RA patients are HLA DR4, Compared to 2025 % of the population at large. • 1st degree relatives of RA patients are 4x ...
... • HLA DR4 is the major halo-type in ethnic group, HLA DR1 in Indians and HLA DW15 in Japanese. N.B : • 50-70 % of caucasian RA patients are HLA DR4, Compared to 2025 % of the population at large. • 1st degree relatives of RA patients are 4x ...
HOMEOSTATIC IMBALANCES of BONE
... women - Get enough calcium & Vitamin D when your body is developing dense bone tissue or take calcium & Vitamin D supplements ARTHRITIS =joint disorder in which over 100 different inflammatory or degenerative diseases damage joints OSTEOARTHRITIS (OA)85% of paging people in US are affected; degener ...
... women - Get enough calcium & Vitamin D when your body is developing dense bone tissue or take calcium & Vitamin D supplements ARTHRITIS =joint disorder in which over 100 different inflammatory or degenerative diseases damage joints OSTEOARTHRITIS (OA)85% of paging people in US are affected; degener ...
AUTOIMMUNE DISEASES
... • Non immune therapy e.g. hormone replacement in thyroid disease, type 1 diabetes • Immune modulatory drugs e.g. Steroids, TNF inhibitors etc. • Anti inflammatory e.g. NSAIDS • Palliative ...
... • Non immune therapy e.g. hormone replacement in thyroid disease, type 1 diabetes • Immune modulatory drugs e.g. Steroids, TNF inhibitors etc. • Anti inflammatory e.g. NSAIDS • Palliative ...
Rheumatoid Arthritis
... Rheumatoid Arthritis (RA) Fast facts • PREVALENCE : An estimated 1.5 million adults in the United States have rheumatoid arthritis. Affects 0.5-1.0% of population • Women are two to three times as likely to be affected as men. • Rheumatoid arthritis (RA) is an inflammatory systemic disease, with th ...
... Rheumatoid Arthritis (RA) Fast facts • PREVALENCE : An estimated 1.5 million adults in the United States have rheumatoid arthritis. Affects 0.5-1.0% of population • Women are two to three times as likely to be affected as men. • Rheumatoid arthritis (RA) is an inflammatory systemic disease, with th ...
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... o Absent – OA, ankylosing spondylitis, gout, chondrocalcinosis, suppurative arthritis, psoriatic arthritis, enteropathic arthritis, Reiter’s syndrome Anti-CCP – antibodies against cyclic-citrullinated peptides (CCPs) present often in RA: o Arginine (post-translational modification by peptidyl ar ...
... o Absent – OA, ankylosing spondylitis, gout, chondrocalcinosis, suppurative arthritis, psoriatic arthritis, enteropathic arthritis, Reiter’s syndrome Anti-CCP – antibodies against cyclic-citrullinated peptides (CCPs) present often in RA: o Arginine (post-translational modification by peptidyl ar ...
NONCOMMUNICABLE DISEASES
... Body fails to produce insulin, glucose builds up in the blood, and cells do not get the energy they need. Autoimmune disease – condition in which the immune system mistakenly attacks itself, targeting the cells, tissue, and organs of a person’s own body. ...
... Body fails to produce insulin, glucose builds up in the blood, and cells do not get the energy they need. Autoimmune disease – condition in which the immune system mistakenly attacks itself, targeting the cells, tissue, and organs of a person’s own body. ...
Arthritis Glossary
... A 2-dimensional image of the body’s tissues. X-ray images can reveal bone deformities, indicating arthritis damage, and the narrowing of joint space, indicating arthritis damage. X-rays can help diagnose arthritis and monitor its progression. ...
... A 2-dimensional image of the body’s tissues. X-ray images can reveal bone deformities, indicating arthritis damage, and the narrowing of joint space, indicating arthritis damage. X-rays can help diagnose arthritis and monitor its progression. ...
AB146PSI-AOAPO_KumariP_30092016
... Abstract Rheumatoid arthritis (RA) is a common autoimmune disorder with unknown etiology. The disease is systemic in nature and predominantly affects bones and cartilage of synovial joints in symmetric fashion. Synovial tissue is the primary target site for inflammation where infiltrated immune cell ...
... Abstract Rheumatoid arthritis (RA) is a common autoimmune disorder with unknown etiology. The disease is systemic in nature and predominantly affects bones and cartilage of synovial joints in symmetric fashion. Synovial tissue is the primary target site for inflammation where infiltrated immune cell ...
Rheumatoid Arthritis “An Autoimmune Mystery”
... stiffness for more than six weeks in a child of 16 years of age or less. There are three types, classified by the number of joints involved and symptoms. Pauciarticular, the most common, four joints or fewer are affected. ...
... stiffness for more than six weeks in a child of 16 years of age or less. There are three types, classified by the number of joints involved and symptoms. Pauciarticular, the most common, four joints or fewer are affected. ...
Document
... Inflammation caused by infiltration of macrophages, T-helper cells and B-plasma cells ...
... Inflammation caused by infiltration of macrophages, T-helper cells and B-plasma cells ...
Rheumatoid Arthritis (RA)
... The process produces an inflammatory response of the synovium (synovitis) secondary to hyperplasia of synovial cells, excess synovial fluid, and the development of pannus in the synovium. The pathology of the disease process often leads to the destruction of articular cartilage and ankylosis of ...
... The process produces an inflammatory response of the synovium (synovitis) secondary to hyperplasia of synovial cells, excess synovial fluid, and the development of pannus in the synovium. The pathology of the disease process often leads to the destruction of articular cartilage and ankylosis of ...
Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long lasting autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly the wrist and hands are involved with typically the same joints involved on both sides of the body. The disease may also affect other parts of the body. This may result in low red blood cells, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often symptoms come on gradually over weeks to months.While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is made mostly on the basis of a person's signs and symptoms. X-rays and laboratory testing may support a diagnosis or exclude other diseases with similar symptoms. Other diseases that may present similarly include systemic lupus erythematosus, psoriatic arthritis, and fibromyalgia among others.The goal of treatment is to improve pain, decrease inflammation, and improve a person's overall functioning. This may be helped by balancing rest and exercise, the use of splints and braces, or the use of assistive devices. Pain medications, steroids, and NSAIDs are frequently used to help with symptoms. A group of medications called disease-modifying antirheumatic drugs (DMARDs) may be used to try to slow the progression of disease. They include the medications hydroxychloroquine and methotrexate. Biological DMARDs may be used when disease does not respond to other treatments. However, they may have a greater rate of adverse effects. Surgery to repair, replace, or fusion joints may help in certain situations. Most alternative medicine treatments are not supported by evidence.RA affects between 0.5 and 1% of adults in the developed world with between 5 and 50 per 100,000 people newly developing the condition each year. Onset is most frequent during middle age and women are affected 2.5 times as frequently as men. In 2013 it resulted in 38,000 deaths up from 28,000 deaths in 1990. The first recognized description of RA was made in 1800 by Dr. Augustin Jacob Landré-Beauvais (1772–1840) of Paris. The term rheumatoid arthritis is based on the Greek for watery and inflamed joints.