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AUTOIMMUNE DISORDERS IMMUNITY  Normal process Promotes inflammation  Fights off invasion   Autoimmune response  Major histocompatibility complex (MHC)   AKA: Human leukocyte antigen (HLA) Self and non-self blurred OSTEOARTHRITIS     Wear and Tear on joints Affects mostly older adults; men & women Joint pain, stiffness Relieved by pain relievers and lowimpact exercise RHEUMATOID ARTHRITIS  Autoimmune disorder    Causes inflamed tissue that destroys cartilage Affects young and middle-age adults; more females than males May be very painful ANKYLOSING SPONDYLITIS  Another type of arthritis  Affects the joints of the spine  Likely genetic  Symptoms / treatment FIBROMYALGIA  “Waste basket diagnosis”  Complex, chronic pain disorder FIBROMYALGIA CONTINUED  Diagnosis include     Detailed history Pain in at least 11 of 18 designated tender points. Other diseases need to be ruled out first Symptoms include:  Widespread pain, fatigue, sleep disorders, fibro “fog”, headaches, anxiety, and/or depression CHRONIC FATIGUE SYNDROME (CFS)  Another “Waste basket diagnosis”  Diagnosis must meet 2 criteria:  Patient must have unexplained, persistent fatigue for 6 months or more (other diseases ruled out)  Four or more “approved” symptoms must be present for at least 6 months  CFS “fog”, unrefreshing sleep, muscle pain, joint pain without swelling, headaches, flu-like symptoms, tender lymph nodes, recurring sore throat SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)     Immune system produces antibodies to body cells causing inflammation and tissue damage. One main characteristic: butterfly facial rash Other symptoms May affect any organ in the body. CELIAC DISEASE  Controversial disorder  Gluten ingestion leads to small intestine damage  Symptoms  Treatment  Related conditions AUTOIMMUNE DISORDERS  Treatment Cognitive Behavior Therapy (CBT)  Graded Exercise Therapy (GET)   The importance of the biopsychosocial model Genetics Environment Biopyschosocial Model Psychology Social
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            