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The Lymphatic System
The Lymphatic System

... – Proteins secreted by virus-infected cells – Bind to healthy cell surfaces to interfere with the ability of viruses to multiply ...
Immune System Quiz
Immune System Quiz

... B. active C. passive D. artificial 7. What immune system disorder results from the immune system attacking loosing its ability to screen new lymphocytes for self-compatibility? A. type I diabetes B. arthritis C. multiple sclerosis D. lupus Short Answer: 8. What is the primary difference between anti ...
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Medical Immunology

... MHC class II molecule CLIP (class II-associated invariant-chain peptide) ...
Slide 1
Slide 1

... • Recognize and kill other cells of the body—why? • Those cells are infected by virus or other intra-cellular pathogen • Cells “process” antigen from virus and “present” it on cell surface embedded in cell membrane so that TCR’s or antibodies can “recognize” that non-self antigen ...
The Cell Membrane
The Cell Membrane

... mast cells and tissue macrophages. These result in increased vascular permeability and the attraction of phagocytes in the process known as chemotaxis. In addition, the latter components of the complement cascade generate a membrane attack complex that induces defects in the cell membrane, resulting ...
Celularni imunski odgovor Aktivacija T limfocita
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... o Myasthenia gravis: antibodies against Ach receptors at neuromuscular junctions cause inhibition of receptors. Therefore skeletal muscle contraction does not occur  paralysis. IgG & IgM antibodies bind to neutrophil and macrophage Fc receptors activating these cells. This results in inflammation. ...
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B cells

... Activated by surface receptors of microbes which creates a trigger cascade to activate other proteins  Leads to lysing of invaders  Some help trigger inflammation response ...
Chapter 37 Objectives and other Animal System Material
Chapter 37 Objectives and other Animal System Material

... 26. Design a flow chart describing the major sequence of events that follows the interaction between antigen presenting macrophages and helper T cells, including both cell-mediated and humoral immunity 27. Describe how cytotoxic T cells recognize and kill their targets 28. Explain how the function o ...
Immune System - World of Teaching
Immune System - World of Teaching

... These are defenses the body uses no matter what the invader may be. These defenses include: ...
Ch6-Immune Desease
Ch6-Immune Desease

... Major Histocompatibility Complex • A genetic “LOCUS” on Chromosome 6, which codes for cell surface compatibility • Also called HLA (Human Leukocyte Antigens) in humans and H-2 in mice • It’s major job is to make sure all self cell antigens are recognized and “tolerated”, because the general rule of ...
Chapter 11 Immune
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... Immune System - network of cells, tissues, and organs that work together to protect the body against foreign “invaders” *In order to do this, the body must be able to recognize foreign substances. ANTIGENS AND IMMUNITY *Define the term antigen and explain it’s significance in immunity Antigens - any ...
the immune system - lpvec
the immune system - lpvec

... • are found in tissues like the skin, near blood vessels. • are activated after antigen binds to a specific type of antibody called IgE that is attached to receptors on the mast cell. • activated mast cells release substances that contribute to inflammation, such as histamine. ...
Chimeric Immune System
Chimeric Immune System

...  Surface proteins (antigens) of pig cells trigger hyperacute rejection, an immediate and massive immune response  Destroys transplanted organ within hours  Research to create transgenic pigs with human antigens on their cells  Transplants from genetically engineered pigs to ...
MATRNAL FETAL RELATIONSHIP AND THE Rh BLOODGROUP
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... MIC is a ligand for the activating site of the NK cell activating receptor NKG2D So MIC-NKG2D is good for immune surveillance However, soluble forms of MIC are produced by tumors maybe to act as a competitive inhibitors that block the recognition of the membrane bound MIC causing a downregulation ...
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... alternative version of parts of the immunoglobulin variable regions. ...
Host : Microbial relationships
Host : Microbial relationships

... produced by gut bacteria can modify ingested chemicals into known carcinogens, although whether this plays a role in the development of colon cancer is not clear. Opportunist pathogens are microbes which do not cause disease in normal hosts but take the opportunity to become pathogenic when the host ...
Chapter 6 - Medical School Pathology
Chapter 6 - Medical School Pathology

... • CYTOKINES are PROTEINS produced by MANY cells, but usually LYMPHOCYTES and MACROPHAGES, numerous roles in acute and chronic inflammation, AND immunity ...
Lesson 1: The Immune System - Lecture Notes | Vaccine Education
Lesson 1: The Immune System - Lecture Notes | Vaccine Education

Hygiene III The Hugiene Hypothesis
Hygiene III The Hugiene Hypothesis

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RBI-205 LECTURE STUDY NOTES BLOOD VI. IMMUNITY A. 1

Immunity
Immunity

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Defense Against Disease
Defense Against Disease

...  Pathogens contain certain chemicals that are foreign to the body and are called antigens  Each lymphocyte carries a specific type of antibody - a protein that has a chemical 'fit' to a certain antigen  When a lymphocyte with the appropriate antibody meets the antigen, the lymphocyte reproduces q ...
T CELL DEFICIENCY - immunology.unideb.hu
T CELL DEFICIENCY - immunology.unideb.hu

... • DEFICIENCY OF EARLY C1-C4 – No C3b and C4b fragments  No CR1-mediated erythrocyte transport of immune complexes – Accumulation of immune complexes in blood, lymph, extracellular fluid  deposition in tissues  tissue demage  macrophage activation  inflammation ...
IMMUNOLOGICAL TOLERANCE
IMMUNOLOGICAL TOLERANCE

... Central tolerance occurs during the maturation of lymphocytes in the central (generative) lymphoid organs, where all developing lymphocytes pass through a stage at which encounter with antigen may lead to cell death or replacement of a self-reactive antigen receptor with a new one ...
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Complement system



The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
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