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WK11-RhoJared
WK11-RhoJared

... Rho proteins by proteases/proteasomes. ...
The Innate Immune Response
The Innate Immune Response

... The cellular receptors that recognize these molecules are often called pattern recognition receptors. The best-defined pattern recognition receptors are a family of proteins called Toll-like receptors (TLRs) that are homologous to the Drosophila protein Toll. ...
Ch 6 Med Term and Ch 15 BS Lymphatic_ImmuneSystems
Ch 6 Med Term and Ch 15 BS Lymphatic_ImmuneSystems

... fights off invaders once they have entered the body ...
Path_ggf_8i
Path_ggf_8i

... The cellular receptors that recognize these molecules are often called pattern recognition receptors. The best-defined pattern recognition receptors are a family of proteins called Toll-like receptors (TLRs) that are homologous to the Drosophila protein Toll. ...
Innate immunity
Innate immunity

... • Elastase and Cathepsin-G. Wide-spectrum proteases able to degrade many bacterial proteins. Elastase is a serin-protease while Cathepsin-G is chymotripsin-like protease. Those enzymes are activated by the low pH and by radicals. In the phagolysosome, the respiratory burst occurs. This is the most p ...
The Lymphatic System and Body Defenses
The Lymphatic System and Body Defenses

lecture # 2 blood - Dr. Justo Lopez Website
lecture # 2 blood - Dr. Justo Lopez Website

... (B lymphocytes, T lymphocytes, and NK lymphocytes) They are the largest WBCs, often two or three times the diameter of an RBC. They are about 3% to 8% of WBC count. The nucleus is large and clearly visible, often light violet. It is typically ovoid, kidney-shaped, or horseshoe-shaped. The cytoplasm ...
Immunopathology I
Immunopathology I

LO 2.29 The student can create representations and
LO 2.29 The student can create representations and

Monoclonal Antibodies Treatment for Various Diseases www
Monoclonal Antibodies Treatment for Various Diseases www

... mainly include medications like Bexxar, Herceptin and Rituxan. Bexxar contains a radioactive iodine molecule and so it does not have a naked form. This medicine has some negative effects like fever, shakes or chills. Medication involving Herceptin is specific for destroying cancer cells in the breas ...
Chapter 15 Adaptive, Specific Immunity and Immunization
Chapter 15 Adaptive, Specific Immunity and Immunization

... Principle antibody activity is to unite with the Ag, to call attention to, or neutralize the Ag for which it was formed • Opsonization – process of coating microorganisms or other particles with specific antibodies so they are more readily recognized by phagocytes • Neutralization – Abs fill the sur ...
Hypersensitivity Reactions
Hypersensitivity Reactions

antigen-antibody reaction
antigen-antibody reaction

... but the precipitates will not sediment. ...
Immunoregulation
Immunoregulation

... – with CTLA-4 engagement of CD80/CD86 → down regulation of Ts (dampens activation) ...
Western Blotting
Western Blotting

... specificity of antibody, we can detect or quantitative the antigen. Keep in mind that the antibody is protein, can also be recognized as an antigen. The major principle to determine the antigen-antibody interaction is to separate the bound form of antigenantibody complex from the free form of either ...
RESPON IMUN TERHADAP INFEKSI
RESPON IMUN TERHADAP INFEKSI

... Each produces a different receptor in the cell membrane Each receptor is composed of 1 molecule each of two different proteins Each receptor binds a specific antigen but has only one binding site Receptor only recognizes antigens which are "presented" to it within another membrane protein of the MHC ...
The Body`s Defenses Against Disease and Injury
The Body`s Defenses Against Disease and Injury

... The body recognizes if a substance is self- or nonself-made as a result of certain antigens that are present on almost all cells of the body except red blood cells. This determines compatibility of tissues and organs that will be grafted or transplanted from a donor. Blood Group Antigens More than 8 ...
Immune system and its importance for homeostasis. Component
Immune system and its importance for homeostasis. Component

... Immune system and its importance for homeostasis. Component parts of the immune system and their cooperation. Barrier functions of the human body and defense mechanisms. Non-specific cellular and humoral immune mechanisms. Specific cellular and humoral immune mechanisms. Phagocytosis and its import ...
Immune system and its importance for homeostasis. Component
Immune system and its importance for homeostasis. Component

... Immune system and its importance for homeostasis. Component parts of the immune system and their cooperation. Barrier functions of the human body and defense mechanisms. Non-specific cellular and humoral immune mechanisms. Specific cellular and humoral immune mechanisms. Phagocytosis and its import ...
Human Biology
Human Biology

... • Chemokines – involved with the inflammatory response – They lead to chemotaxis and activation ...
Infectious Diseases
Infectious Diseases

... a link to onset of autism. No clinical studies support this ...
The immune system  Dr. Ali Ebneshahidi © 2016 Ebneshahidi
The immune system Dr. Ali Ebneshahidi © 2016 Ebneshahidi

What is an Autoimmune Disease?
What is an Autoimmune Disease?

... is a pathogen and is harmful, even though it isn't. This is called autoimmunity; "auto" means "self", so "autoimmunity" is an immune response against itself. When an autoimmune reaction does harm the body it is called an autoimmune disease. ...
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BRUCELLOSIS AND THE INNATE IMMUNE SYSTEM (Part 3)
BRUCELLOSIS AND THE INNATE IMMUNE SYSTEM (Part 3)

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Complement system



The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
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