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lecture # 7 the immune system
lecture # 7 the immune system

... It contributes to tissue cleanup. swelling compresses veins and reduces venous drainage forces open valves of lymphatic capillaries promoting lymphatic drainage. lymphatics collect and remove bacteria, dead cells, proteins, and tissue debris better than blood capillaries. ...
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... • Explain how physical and chemical barriers protect the body against pathogens. • Describe the inflammatory response. • Explain the role of phagocytes. • Explain the difference between active and passive immunity. ...
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...  They affect the body by  Producing toxins or poisons  Killing or damaging cells in certain parts of the body  Most can be killed by medicines such as antibiotics ...
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... Extrinsic alveolitis • Caused by deposition if insoluble immune complexes in the lung tissue. The complexes are formed from exogenous antigen and excess if antibodies of IgG class. • 6-8 hours after exposition the patient suffers from dry cough, dyspnea, increased body ...
prevent - Model High School
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... Vitamin D plays a role in immune response, and may be critical for fighting off viruses. • Vitamin D is fat-soluble and can accumulate to toxic levels. A blood test can determine if a person needs to take Vitamin D. ...
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... Bone Marrow: The yellow tissue in the center of your bones that is responsible for making white blood cells that are destined to become lymphocytes. Lymphocytes: A small white blood cell that plays a large role in defending the body against disease. There are two main types of lymphocytes: B-cells a ...
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... – Primary function: limits activation of complement pathway • Binds complement cleavage products C3b and C4b, thus acting as a cofactor to inactivate them to iC3b and iC4b ...
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... • Antigens stimulate an immune response via the production of antibodies • When a pathogen invades the body, it is engulfed by wandering macrophages which present the antigenic fragments on its surface • This macrophage becomes an antigen-presenting cell, and presents the antigen to helper T cells ( ...
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... indicators of infection which in turn activates the production of pro-inflammatory cytokines (= immunesystem activating chemicals). In addition to the cell-to-cell interactions underlying  inflammation, the inflammatory response involves localized increases in blood flow, leakage of blood vessels, ...
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... regional lymph nodes, with immune cells travelling between these distinct sites. Antigen-presenting cells such as dendritic cells migrate into the tumour microenvironment and take up tumour antigens. Antigen-presenting cells travel to regional lymph nodes, where they present the tumour antigens to n ...
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Complement system



The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
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