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PDF - Temple Biology
PDF - Temple Biology

... Fay and Wu (1999) examine a historical model in which a population quickly shrinks, stays small for some time, and then suddenly recovers its original population size, at which it stays until samples are drawn from it. This is a bottleneck model of the kind traditionally used in population genetics ...
The Ancestry of a Gene - 2009
The Ancestry of a Gene - 2009

... gene in the population are descended only occurs in small (N < 1000) populations. In large populations (N > 1 000 000) crossing over (recombination) within the gene provides that there is an ancestral pool rather than a single ancestor of the gene. In the absence of recombination there is a common a ...
HIV in the Workplace
HIV in the Workplace

... complex interactions between the human immunodeficiency virus (HIV) and the workplace are still being defined and understood. While occupationally acquired infections from HIV are of much individual concern, they are rare events [2]. HIV is neither the most common nor the most infectious bloodborne ...
January 8, 2014 - HIV Structure, Lifecycle and Replication
January 8, 2014 - HIV Structure, Lifecycle and Replication

... A – Acquired – AIDS is not something you inherit from your parents. You acquire AIDS after birth. I – Immuno – Your body's immune system includes all the organs and cells that work to fight off infection or disease. D – Deficiency – You get AIDS when your immune system is "deficient," or isn't worki ...
Selective Pressures on Genomes in Molecular Evolution
Selective Pressures on Genomes in Molecular Evolution

... many ways to express a concept in English words, there are many messages (sequences) that contain the same meaning (information), and thus in reality not all mutations are deleterious. If a mutation modifies the genetic sequence without affecting the message, but does make it more robust to further ...
Slide 1
Slide 1

... • Women with influenza should continue breastfeeding and increase feeding frequency • Antiviral medication treatment or prophylaxis is not a contraindication for breastfeeding ...
Slide 1 - Northwest Center for Public Health Practice
Slide 1 - Northwest Center for Public Health Practice

... • Women with influenza should continue breastfeeding and increase feeding frequency • Antiviral medication treatment or prophylaxis is not a contraindication for breastfeeding ...
Herpes Simplex Virus (HSV)
Herpes Simplex Virus (HSV)

... • Specimens: CMV can be isolated from the urine, saliva, breast milk, semen, cervical secretions and blood leucocytes. • Demonstration of cytomegalic cell: The histologic hallmark of CMV infection is the cytomegalic cell, which is an enlarged cell that contains a dense, central, “owl’s-eye,” • Isola ...


... particular influenza season. This condition became reportable in January 2009. B) Influenza-associated Pediatric Mortality (ODRS): Influenza-associated pediatric mortalities are reported into ODRS by CCBH and hospital staff. Pediatric deaths can be an indicator of the severity of illness during the ...
2/20/12 Viruses
2/20/12 Viruses

... • Viruses replicate only in certain types of cells or in whole organisms • Bacterial viruses are easiest to grow; model systems • Animal viruses (and some plant viruses) can be cultivated in tissue or cell cultures • Plant viruses typically are most difficult because study often requires growth of w ...
DNA viruses - WordPress.com
DNA viruses - WordPress.com

... • Viruses replicate only in certain types of cells or in whole organisms • Bacterial viruses are easiest to grow; model systems • Animal viruses (and some plant viruses) can be cultivated in tissue or cell cultures • Plant viruses typically are most difficult because study often requires growth of w ...
The human immunodeficiency virus
The human immunodeficiency virus

... Disease overview: The human immunodeficiency virus (HIV) is a lentivirus, a subgroup of retrovirus, that causes HIV infection and over time acquired immunodeficiency syndrome(AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic ...
Table 1. Cuyahoga County Influenza Data Dashboard
Table 1. Cuyahoga County Influenza Data Dashboard

... particular influenza season. This condition became reportable in January 2009. B) Influenza-associated Pediatric Mortality (ODRS): Influenza-associated pediatric mortalities are reported into ODRS by CCBH and hospital staff. Pediatric deaths can be an indicator of the severity of illness during the ...
Class Exercise: Relationship between organismal performance and
Class Exercise: Relationship between organismal performance and

... Selection is what we usually think of as the major force causing evolutionary change. Simply put, selection occurs when certain genotypes have higher propensities for survival and/or reproduction than others. These differences are usually defined as fitnesses, the average number of offspring for an ...
Laboratory #2: ELISA Immuno Explorer
Laboratory #2: ELISA Immuno Explorer

... sheep with the antigen and then harvest the antibodies in their blood to use as a diagnostic tool in the lab. ...
Simulated ecology-driven sympatric speciation
Simulated ecology-driven sympatric speciation

... The theory of evolution studies processes that are extremely complex and whose characteristic times usually extend over many human life spans. Because of this inherent complexity, these studies do not lend themselves readily to the establishment of discrete, falsifiable hypotheses. For this reason, ...
pharyngitis, tonsillitis
pharyngitis, tonsillitis

... virostatics - nebulized ribavirin ...
Viruses – Invisible Invaders, Amazing Allies
Viruses – Invisible Invaders, Amazing Allies

...  Upper and Lower Respiratory Tract Infections (URTI, LRTI)  Viremia and Sepsis  Infections of Central Nervous System ...
Virus Diseases Of Tomato - Alabama Cooperative Extension System
Virus Diseases Of Tomato - Alabama Cooperative Extension System

... of the virus for tomato and other solanaceous crops. The virus does not appear to be seed-transmitted. Symptoms on tomato vary according to PVY strain, plant age, varieties infected, and environmental conditions. General symptoms on tomato are faint mottling and slight distortion of the leaves (Figu ...
Sequence analysis of selected nucleotide sequences of abortogenic
Sequence analysis of selected nucleotide sequences of abortogenic

... Glycoproteins are divided into those that are essential for virus replication (gB, gD, gH / L, gK) and those that are not (gC, gE, gI, gG, gM) (Cairns et al. 2003). Due to the localization of viral glycoproteins on the virus particles surface they are molecules coming into direct contact with the ho ...
Annu. Rev. Ecol. Evol. Syst
Annu. Rev. Ecol. Evol. Syst

... medicine and agronomy. New viruses are constantly emerging while old ones evolve and challenge the latest advances in antiviral pharmaceutics, thus generating tremendous social alarm, sanitary problems, and economical losses. However, they constitute very powerful tools for experimental evolution. T ...
PICORNAVIRIDAE
PICORNAVIRIDAE

... 2. Viral genomic RNA has a viral protein (VPg) at its 5’ end instead of a methylated nucleotide cap structure. 3. The long UTR at the 5’ end contains an internal ribosome entry site (IRES). The IRES allows direct translation of the polyprotein. 4. The P1 region encodes the structural polypeptides. 5 ...
The 20th International BioInformatics Workshop on Virus Evolution
The 20th International BioInformatics Workshop on Virus Evolution

... Anne-Mieke Vandamme was trained as biochemist, and holds a PhD in sciences since 1986. She joined the Rega Institute at the Katholieke Universiteit Leuven in 1990, where she started a unit on virus genetic testing for clinical practice. Together with Professor Van Ranst, she founded a new division, ...
this also allows him to have quicker starts and
this also allows him to have quicker starts and

... 1. Determine whether the inherited mutation is helpful, neutral or harmful to the organism and their reproductive success, given the environment in which the organism lives. 2. State why the mutation is helpful or harmful in that ...
Ebola - Austin Community College
Ebola - Austin Community College

... Do  not  travel  to  endemic  areas  and  avoid  direct  contact  with  bodily  fluids  of  infected  hosts  through  the   use  of  masks,  gloves,  and  goggles  (4).  Community  awareness  is  significant  for  prevention  and  reduc ...
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Viral phylodynamics



Viral phylodynamics is defined as the study of how epidemiological, immunological, and evolutionary processes act and potentially interact to shape viral phylogenies.Since the coining of the term in 2004, research on viral phylodynamics has focused on transmission dynamics in an effort to shed light on how these dynamics impact viral genetic variation. Transmission dynamics can be considered at the level of cells within an infected host, individual hosts within a population, or entire populations of hosts.Many viruses, especially RNA viruses, rapidly accumulate genetic variation because of short generation times and high mutation rates.Patterns of viral genetic variation are therefore heavily influenced by how quickly transmission occurs and by which entities transmit to one another.Patterns of viral genetic variation will also be affected by selection acting on viral phenotypes.Although viruses can differ with respect to many phenotypes, phylodynamic studies have to date tended to focus on a limited number of viral phenotypes.These include virulence phenotypes, phenotypes associated with viral transmissibility, cell or tissue tropism phenotypes, and antigenic phenotypes that can facilitate escape from host immunity.Due to the impact that transmission dynamics and selection can have on viral genetic variation, viral phylogenies can therefore be used to investigate important epidemiological, immunological, and evolutionary processes, such as epidemic spread, spatio-temporal dynamics including metapopulation dynamics, zoonotic transmission, tissue tropism, and antigenic drift.The quantitative investigation of these processes through the consideration of viral phylogenies is the central aim of viral phylodynamics.
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