![ICD-9-CM/ICD-10-CM Crosswalk for Adult Male](http://s1.studyres.com/store/data/008023242_1-451ecdb95f70b699301bcf5eae0a75c6-300x300.png)
ICD-9-CM/ICD-10-CM Crosswalk for Adult Male
... antiestrogens, antiandrogens, not elsewhere classified, accidental (unintentional) (X depends on initial (A), subsequent (D), or sequela (S) encounter) T38.6X2X Poisoning by antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified, intentional self-harm (X depends on initial (A), s ...
... antiestrogens, antiandrogens, not elsewhere classified, accidental (unintentional) (X depends on initial (A), subsequent (D), or sequela (S) encounter) T38.6X2X Poisoning by antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified, intentional self-harm (X depends on initial (A), s ...
trelstar depot 3.75 mg
... TRELSTARTM DEPOT was studied in a randomized, active control trial of 277 men with advanced prostate cancer. The clinical trial population consisted of 59.9% Caucasian, 39.3% Black, and 0.8% Other. There was no difference observed with triptorelin response between racial groups. Men were between 47 ...
... TRELSTARTM DEPOT was studied in a randomized, active control trial of 277 men with advanced prostate cancer. The clinical trial population consisted of 59.9% Caucasian, 39.3% Black, and 0.8% Other. There was no difference observed with triptorelin response between racial groups. Men were between 47 ...
The Bioanalytical Evaluation of Novel Therapeutic Modalities in
... details on the integrity of the modality on the molecular level Multiple biomarkers/proteins can be simultaneously measure by detecting unique peptides from each and unique forms following enrichment by affinity capture techniques therapeutic, target, ligand, biomarker, etc. ...
... details on the integrity of the modality on the molecular level Multiple biomarkers/proteins can be simultaneously measure by detecting unique peptides from each and unique forms following enrichment by affinity capture techniques therapeutic, target, ligand, biomarker, etc. ...
An Uncontrolled Clinical Trial for Treatment of
... clomiphene citrate, and tamoxifen citrate in returning the HPGA to normal physiological function in adult males suffering from androgen induced hypogonadotropic hypogonadism. In the case of decreased testicular function manifested by low testosterone levels, it is of primary importance to first retu ...
... clomiphene citrate, and tamoxifen citrate in returning the HPGA to normal physiological function in adult males suffering from androgen induced hypogonadotropic hypogonadism. In the case of decreased testicular function manifested by low testosterone levels, it is of primary importance to first retu ...
Chapter 20 Anus, Rectum, and Prostate Examination of the anus
... Colon cancer or familial cancer syndromes Prostatic cancer Personal and Social History Travel history: areas with high incidence of parasitic infestation, including zones in the United ...
... Colon cancer or familial cancer syndromes Prostatic cancer Personal and Social History Travel history: areas with high incidence of parasitic infestation, including zones in the United ...
Principles of early drug discovery
... thereby preventing it from being used as a translation template (reviewed in Castanotto and Rossi, 2009). However, RNAi technology still has the major problem of delivery to the target cell, but many viral and non-viral delivery systems are currently under investigation (for review see Whitehead et ...
... thereby preventing it from being used as a translation template (reviewed in Castanotto and Rossi, 2009). However, RNAi technology still has the major problem of delivery to the target cell, but many viral and non-viral delivery systems are currently under investigation (for review see Whitehead et ...
narcotics - The Podiatry Institute
... acute and chronic pain. It also is indicated preoperatively to sedate and allay apprehension, facilitate induction of anesthesra and reduce anesthetic dosage. Morphine sulfate is not as potent orally because of its first pass metabolism. Oral administration is 7/3 to 7/6 as effective as parenteral d ...
... acute and chronic pain. It also is indicated preoperatively to sedate and allay apprehension, facilitate induction of anesthesra and reduce anesthetic dosage. Morphine sulfate is not as potent orally because of its first pass metabolism. Oral administration is 7/3 to 7/6 as effective as parenteral d ...
Prediction of survival in prostate cancer
... PSA is a kallikrein‐like serine protease produced almost exclusively by the epithelial cells of the prostate. For practical purposes, it is organ‐specific but not cancer‐ specific, and serum levels may be elevated in the presence of benign prostatic hyperplasia (BPH), prostatitis and other non‐mal ...
... PSA is a kallikrein‐like serine protease produced almost exclusively by the epithelial cells of the prostate. For practical purposes, it is organ‐specific but not cancer‐ specific, and serum levels may be elevated in the presence of benign prostatic hyperplasia (BPH), prostatitis and other non‐mal ...
DIsCOvERy sTuDIO® sCIENCE PORTFOlIO
... Leverage this industry-standard program to study the energetics and flexibility of molecules - from small ligands to multi-component physiological complexes, using the industry standard in force field technology, CHARMM (Chemistry at HARvard Macromolecular Mechanics). DS CHARMm is regularly updated ...
... Leverage this industry-standard program to study the energetics and flexibility of molecules - from small ligands to multi-component physiological complexes, using the industry standard in force field technology, CHARMM (Chemistry at HARvard Macromolecular Mechanics). DS CHARMm is regularly updated ...
Cancer Smart Bomb, Part I
... its peak concentration in the blood within 40 minutes. This form is broken down very quickly into its metabolites in the liver and excreted somewhat quickly, but still has some metabolic effects for as long as four hours. Human studies have shown this form to have a somewhat poor and erratic absorpt ...
... its peak concentration in the blood within 40 minutes. This form is broken down very quickly into its metabolites in the liver and excreted somewhat quickly, but still has some metabolic effects for as long as four hours. Human studies have shown this form to have a somewhat poor and erratic absorpt ...
What is the evidence for use of weekly alendronic acid in men?
... Miller et al conducted an RCT to examine the effect of alendronic acid 70mg once weekly in 167 men with osteoporosis diagnosed either by BMD at the lumbar spine and femoral neck, or the presence of an osteoporotic fracture (14). The study showed that 12 months of treatment significantly increased BM ...
... Miller et al conducted an RCT to examine the effect of alendronic acid 70mg once weekly in 167 men with osteoporosis diagnosed either by BMD at the lumbar spine and femoral neck, or the presence of an osteoporotic fracture (14). The study showed that 12 months of treatment significantly increased BM ...
CELL-SELEX: a Technology Comes of Age - Novel Perspectives of Aptamer-Based Therapeutics
... generates aptamers with high binding affinity and specificity. Their advantages have made them very promising in analytical, diagnostic and therapeutic applications [12-15]. As small molecules , with a half-life of minutes to hours due to nuclease degradation, aptamers can be rapidly cleaned from th ...
... generates aptamers with high binding affinity and specificity. Their advantages have made them very promising in analytical, diagnostic and therapeutic applications [12-15]. As small molecules , with a half-life of minutes to hours due to nuclease degradation, aptamers can be rapidly cleaned from th ...
12th Conference in Advanced Medicinal Chemistry
... Chemistry. Unfortunately, some of them are not among us any more. Arnold Beckett passed away some months ago, and Corwin Hansch only few days before this conference. According to the IUPAC definition prepared for publication by C.G. Wermuth, C.R. Ganellin, P. Lindberg and L.A. Mitscher, in 1998, Med ...
... Chemistry. Unfortunately, some of them are not among us any more. Arnold Beckett passed away some months ago, and Corwin Hansch only few days before this conference. According to the IUPAC definition prepared for publication by C.G. Wermuth, C.R. Ganellin, P. Lindberg and L.A. Mitscher, in 1998, Med ...
Acute lung injury as a possible adverse drug reaction related... gefitinib CASE STUDY R. Ieki, E. Saitoh, M. Shibuya
... 3 and 4 adverse events were rare, there was a relatively high incidence of dyspnoea, which was considered to be disease related. Preliminary data from a phase-II study with gefitinib showed an 18.7% response rate in 210 patients with NSCLC who had progressed after first- or second-line chemotherapy. ...
... 3 and 4 adverse events were rare, there was a relatively high incidence of dyspnoea, which was considered to be disease related. Preliminary data from a phase-II study with gefitinib showed an 18.7% response rate in 210 patients with NSCLC who had progressed after first- or second-line chemotherapy. ...
Interaction of quinidine, disopyramide and
... side effects [10, 23]. Albinos are deprived of such protection, which is why some toxic effects of drug administration occur much faster [24, 25]. The drugs binding to melanin include sympathomimetic amines [26], antibiotics [27, 28], b-blockers [23, 29, 30], antimalarials [31–34], local anaesthetic ...
... side effects [10, 23]. Albinos are deprived of such protection, which is why some toxic effects of drug administration occur much faster [24, 25]. The drugs binding to melanin include sympathomimetic amines [26], antibiotics [27, 28], b-blockers [23, 29, 30], antimalarials [31–34], local anaesthetic ...
Lecture 4, 5- drugs used in bronchial asthma & COPD
... Act by blocking muscarinic receptors. Given by aerosol inhalation Quaternary derivatives of atropine Does not diffuse into the blood Do not enter CNS, minimal systemic side effects. Delayed onset of action Ipratropium has short duration of action 3-5 hr Tiotropium has longer duration ...
... Act by blocking muscarinic receptors. Given by aerosol inhalation Quaternary derivatives of atropine Does not diffuse into the blood Do not enter CNS, minimal systemic side effects. Delayed onset of action Ipratropium has short duration of action 3-5 hr Tiotropium has longer duration ...
Aminoglycosides
... 1) They are BACTERICIDAL, effective only ≠ aerobic bacteria [they are inactive ≠ anaerobic bacteria that transport through cell membrane is energy-requiring process that is oxygen-dependent]. 2) They are limited use and for only severe G-ve infections due to their toxicity [cause ototoxicity & nep ...
... 1) They are BACTERICIDAL, effective only ≠ aerobic bacteria [they are inactive ≠ anaerobic bacteria that transport through cell membrane is energy-requiring process that is oxygen-dependent]. 2) They are limited use and for only severe G-ve infections due to their toxicity [cause ototoxicity & nep ...
Structure-based drug design - Biomolecular Structure Center
... of new structures solved, since many protein structures are kept classified by pharmaceutical companies. The rate of structure determinations has doubled in the last two years, and this rate is still increasing [9]. The large number of structural investigations on medically relevant proteins reflect ...
... of new structures solved, since many protein structures are kept classified by pharmaceutical companies. The rate of structure determinations has doubled in the last two years, and this rate is still increasing [9]. The large number of structural investigations on medically relevant proteins reflect ...
Neurological Agents Chart
... Issues: high incidence of pain on injection and postoperative N/V Metabolism: extensive hepatic metabolism + in the plasma Rapid onset: with profound analgesia MOA: non-competitive antagonist of NMDA receptor Issues: only IV anesthetic to produce dose-related ...
... Issues: high incidence of pain on injection and postoperative N/V Metabolism: extensive hepatic metabolism + in the plasma Rapid onset: with profound analgesia MOA: non-competitive antagonist of NMDA receptor Issues: only IV anesthetic to produce dose-related ...
Phage display for target-based antibacterial drug discovery
... pathogens, a wide range of targets involved in different microbial pathways is now accessible for antibacterial drug discovery. The basic criterion for the selection of a gene product as an antibacterial target is that it is essential for the survival of the pathogen in the host1,31. Thus, several d ...
... pathogens, a wide range of targets involved in different microbial pathways is now accessible for antibacterial drug discovery. The basic criterion for the selection of a gene product as an antibacterial target is that it is essential for the survival of the pathogen in the host1,31. Thus, several d ...
4) Van der waals interaction
... intropy induced. *What's the difference between entropy induced and enthalpy induced? - the H-bond Make enthalpy : I must pay energy to break the bond and free the molecule, so it is not favored WHILE Hydrophobic increased the entropy in the system, so this will push the interaction to happen. S ...
... intropy induced. *What's the difference between entropy induced and enthalpy induced? - the H-bond Make enthalpy : I must pay energy to break the bond and free the molecule, so it is not favored WHILE Hydrophobic increased the entropy in the system, so this will push the interaction to happen. S ...
Glucocorticoid Increases Angiotensin II Type 1
... FIG 2. Bar graph shows time course for the effect of dexamethasone on relative Increase in numbers of angiotensin II type 1 (AT,) receptors. Vascular smooth muscle cells were Incubated for the Indicated time periods with 1 ^mol/L dexamethasone. AT, receptor density was calculated from Scatchard plot ...
... FIG 2. Bar graph shows time course for the effect of dexamethasone on relative Increase in numbers of angiotensin II type 1 (AT,) receptors. Vascular smooth muscle cells were Incubated for the Indicated time periods with 1 ^mol/L dexamethasone. AT, receptor density was calculated from Scatchard plot ...
Inhibition of CWR22Rn1 tumor growth and PSA secretion in athymic
... Implantation of tumors in nude mice and treatments with tea polyphenols This study was performed to analyze the chemopreventive/therapeutic effects of tea polyphenols against CaP in athymic nude mice implanted with androgensensitive human prostate carcinoma CWR22Rn1 cells. The rationale for the choi ...
... Implantation of tumors in nude mice and treatments with tea polyphenols This study was performed to analyze the chemopreventive/therapeutic effects of tea polyphenols against CaP in athymic nude mice implanted with androgensensitive human prostate carcinoma CWR22Rn1 cells. The rationale for the choi ...
Revivogen Scalp Therapy Serum Review
... androgen receptors. What it does is it out competes for spaces in androgen receptors that can A 3 Month Supply of Revivogen otherwise detect DHT. All the other linoleic acids, unfortuantely, are not active DHT blockers and are a useless inclusion. [Source 1] However, gamma linoleic acid is listed as ...
... androgen receptors. What it does is it out competes for spaces in androgen receptors that can A 3 Month Supply of Revivogen otherwise detect DHT. All the other linoleic acids, unfortuantely, are not active DHT blockers and are a useless inclusion. [Source 1] However, gamma linoleic acid is listed as ...
Discovery and development of antiandrogens
![](https://commons.wikimedia.org/wiki/Special:FilePath/Androgen_receptor.png?width=300)
In the 1960s, the first antiandrogen, or androgen antagonist, was discovered. Antiandrogens antagonise the androgen receptor (AR) and thereby block the biological effects of testosterone and dihydrotestosterone (DHT). Antiandrogens are important for men with hormonally responsive diseases like prostate cancer, benign prostatic hyperplasia (BHP), acne, seborrhea, hirsutism and androgen alopecia. Antiandrogens are mainly used for the treatment of prostate diseases. Research from 2010 suggests that ARs could be linked to the disease progression of triple-negative breast cancer and that antiandrogens can potentially be used to treat it.As of 2010 antiandrogens are small molecules and can be either steroidal or nonsteroidal depending on ligand chemistry. Steroidal antiandrogens share a similar steroid structure, while nonsteroidal antiandrogens may have structurally distinctive pharmacophores. Only a limited number of compounds are available for clinical use despite the fact that a very large variety of antiandrogen compounds have been discovered and researched.