Chapter 6: Alkynes, reactions of alkynes, and multistep synthesis
... c. easly get aldehyde 5. Hydrogenation a. usually can’t stop at alkene b. can stop only if using “poison” catalyst (Lindlar catalyst) c. get cis alkene for syn addition with Lindlar d. to get trans, use Na or Li in liquid ammonia (-78ºC) e. this is radical addition ...
... c. easly get aldehyde 5. Hydrogenation a. usually can’t stop at alkene b. can stop only if using “poison” catalyst (Lindlar catalyst) c. get cis alkene for syn addition with Lindlar d. to get trans, use Na or Li in liquid ammonia (-78ºC) e. this is radical addition ...
CHE-06 year 2004
... Which SN2 reaction out of each of the following pairs would you expect to take place more (4) rapidly in a protic solvent? Explain your answer. ...
... Which SN2 reaction out of each of the following pairs would you expect to take place more (4) rapidly in a protic solvent? Explain your answer. ...
Organic Chemistry 1 1st Hour Exam Student ID # Name
... (b) Explain why one product is the major isomer based on their reaction coordinate diagrams that show the two different reaction progresses (or pathways) to give the two different products, the major and the minor products. Explain the reaction results using the Hammond postulate. ...
... (b) Explain why one product is the major isomer based on their reaction coordinate diagrams that show the two different reaction progresses (or pathways) to give the two different products, the major and the minor products. Explain the reaction results using the Hammond postulate. ...
Asymmetric Organocatalysis
... One of these approaches consists in activating the acceptors – mostly α,β-unsaturated aldehydes (R4 = H) and ketones (R4 = alkyl) – by reversible conversion to a chiral iminium ion. As shown in Scheme 4.2a, reversible condensation of an α,β-unsaturated carbonyl compound with a chiral secondary ami ...
... One of these approaches consists in activating the acceptors – mostly α,β-unsaturated aldehydes (R4 = H) and ketones (R4 = alkyl) – by reversible conversion to a chiral iminium ion. As shown in Scheme 4.2a, reversible condensation of an α,β-unsaturated carbonyl compound with a chiral secondary ami ...
Lecture 21 Enzyme mechanisms
... the presence of charge group near the active site, the pK’s of amino acid side chains in proteins may vary by several units from their nominal values. Distributions of charge near the active sites of enzymes are arranged in such a way that it can stabilize the transition states of the catalyzed reac ...
... the presence of charge group near the active site, the pK’s of amino acid side chains in proteins may vary by several units from their nominal values. Distributions of charge near the active sites of enzymes are arranged in such a way that it can stabilize the transition states of the catalyzed reac ...
15 - MSU Chemistry
... The starting material in the first reaction has a plane of symmetry so it is achiral: the stereochemistry shows only which diastereoisomer we have. Attack by the amine nucleophile at either end ...
... The starting material in the first reaction has a plane of symmetry so it is achiral: the stereochemistry shows only which diastereoisomer we have. Attack by the amine nucleophile at either end ...
Unit 3: Reactions of Alkenes. Thermodynamics and Kinetics
... C-H DH = 101 kcal/mol H-Br DH = 87 kcal/mol DHtotal = 148 kcal/mol Total DH change = +47 kcal/mol ...
... C-H DH = 101 kcal/mol H-Br DH = 87 kcal/mol DHtotal = 148 kcal/mol Total DH change = +47 kcal/mol ...
슬라이드 1
... The addition of halides to transition-metal species with low oxidation states is a common reaction in transition-metal chemistry and is called oxidative addition. The formal oxidation state of copper after addition is 3+. This step is followed by combination of two of the alkyl groups from c ...
... The addition of halides to transition-metal species with low oxidation states is a common reaction in transition-metal chemistry and is called oxidative addition. The formal oxidation state of copper after addition is 3+. This step is followed by combination of two of the alkyl groups from c ...
Development of a Greener Selective Acylation Method for Steroids
... The reaction using dichloromethane as a solvent was complete on adding the catalyst to the reaction mixture. When ethyl acetate was used as a solvent, the starting material was not completely used up (Figure 2). Both reactions led to the formation of a product with the same retention time of the ref ...
... The reaction using dichloromethane as a solvent was complete on adding the catalyst to the reaction mixture. When ethyl acetate was used as a solvent, the starting material was not completely used up (Figure 2). Both reactions led to the formation of a product with the same retention time of the ref ...
Mechanistic Assignment
... CH3CH2SH is a good Lewis base. Why doesn’t it just react with the Lewis acid (BF3)? You will likely want to refer to your mechanism to explain why that is a better reaction path. ...
... CH3CH2SH is a good Lewis base. Why doesn’t it just react with the Lewis acid (BF3)? You will likely want to refer to your mechanism to explain why that is a better reaction path. ...
Exam 2 Review Sheet for Friday, March 2 Exam Chem 1120, Spring
... • Name and draw structural formulas for alkanes, cycloalkanes, alkenes, cycloalkenes, alkynes, aromatics, halides, alcohols, ethers, aldehydes, ketones, acids, esters, amines, and amides. Be sure and know common names for structures covered in class. Describe the general properties of each type of c ...
... • Name and draw structural formulas for alkanes, cycloalkanes, alkenes, cycloalkenes, alkynes, aromatics, halides, alcohols, ethers, aldehydes, ketones, acids, esters, amines, and amides. Be sure and know common names for structures covered in class. Describe the general properties of each type of c ...
with answers
... Pauli Principle: No two electrons in an atom can have all four quantum numbers identical. Or an orbital can be occupied by at most two electrons, which must then have antiparallel spin. Hund’s Rule: Orbitals will be filled with electrons in order of increasing energy; orbitals of the same energy wil ...
... Pauli Principle: No two electrons in an atom can have all four quantum numbers identical. Or an orbital can be occupied by at most two electrons, which must then have antiparallel spin. Hund’s Rule: Orbitals will be filled with electrons in order of increasing energy; orbitals of the same energy wil ...
TV RajanBabu Chemistry, 730 Autumn 1997
... Enolate generation (Z and E): Ireland model Examples of substituent, solvent, counter ion, base effects on enolate stereochemistry Boron enolates, including limitations Break down of Z-T transition states: two cases (explain with the aid of models): Aldol reactions of silyl enol ethers with Lewis ac ...
... Enolate generation (Z and E): Ireland model Examples of substituent, solvent, counter ion, base effects on enolate stereochemistry Boron enolates, including limitations Break down of Z-T transition states: two cases (explain with the aid of models): Aldol reactions of silyl enol ethers with Lewis ac ...
1. Four of the structural isomers of C4H10O are alcohols. One of
... Calculate the maximum possible mass of butan-2-ol which could be obtained in the above experiment. ...
... Calculate the maximum possible mass of butan-2-ol which could be obtained in the above experiment. ...
Catalytic Hydrogenation of Alkenes: Relative Stability of
... leaving group. The transition state leading to 2-methyl-2-butene is slightly more stabilized than the one leading to 2-methyl1-butene. The more stable product is formed faster because the structure of the transition state resembles that of the ...
... leaving group. The transition state leading to 2-methyl-2-butene is slightly more stabilized than the one leading to 2-methyl1-butene. The more stable product is formed faster because the structure of the transition state resembles that of the ...
Dehydration of 3,3-dimethyl-2-butanol to make alkenes March 1 & 3
... Do a GC analysis – Determine the % of your alkenes – Determine the % of your starting material (3,3-dimethyl-2butanol) ...
... Do a GC analysis – Determine the % of your alkenes – Determine the % of your starting material (3,3-dimethyl-2butanol) ...
Microsoft Word - Final Exam Study Guide
... equilibria, pKa’s, trends in acidity/basicity, functional groups, alkane nomenclature, conformational analysis, Newman projections, causes of strain, cyclohexane ring ...
... equilibria, pKa’s, trends in acidity/basicity, functional groups, alkane nomenclature, conformational analysis, Newman projections, causes of strain, cyclohexane ring ...
chemistry 2 - waiukucollegescience
... Draw structural formulae for the following organic compounds. (a) 2-chloropropane ...
... Draw structural formulae for the following organic compounds. (a) 2-chloropropane ...
• Pergamon
... A variety of substituted 2-methylpyrroles underwent allylic oxidation with the perchlorinated metalloporphyrin 2 and iodosylbenzene in 'IFAlCH2CI2 (9:1). Subsequent addition of an a-free pyrrole to the same reaction mixture afforded an efficient one-pot route to dipyrromethanes. ...
... A variety of substituted 2-methylpyrroles underwent allylic oxidation with the perchlorinated metalloporphyrin 2 and iodosylbenzene in 'IFAlCH2CI2 (9:1). Subsequent addition of an a-free pyrrole to the same reaction mixture afforded an efficient one-pot route to dipyrromethanes. ...
Chemistry: Selected Topics
... 1 Understanding the relation between reaction rate and reaction mechanism 2 Being able to develop the rate equation of a chemical reaction 3 Knowledge of the properties and synthesis of important types of inorganic polymers 4 Knowledge of the relation between chemical structure and properties of ...
... 1 Understanding the relation between reaction rate and reaction mechanism 2 Being able to develop the rate equation of a chemical reaction 3 Knowledge of the properties and synthesis of important types of inorganic polymers 4 Knowledge of the relation between chemical structure and properties of ...
Eliminations
... SN1/SN2/E2/E1 summary/comparison: (1) Primary alkyl halides will prefer SN2 unless a strong hindered base is used in which case E2 will be favored. For example, t-‐butoxide is a sterically hindered base. ...
... SN1/SN2/E2/E1 summary/comparison: (1) Primary alkyl halides will prefer SN2 unless a strong hindered base is used in which case E2 will be favored. For example, t-‐butoxide is a sterically hindered base. ...
Organic Reactions
... Rearrangement - change in the alkyl group structure; may occur during some substitution or elimination reactions ...
... Rearrangement - change in the alkyl group structure; may occur during some substitution or elimination reactions ...
Name__________________________Review Organic Reactions
... A) CH 3COOH + CH3OH ® CH 3COOCH 3 + H 2O B) C2H6 + Cl 2 ® C2H5Cl + HCl C) C3H 6 + H2 ® C3H 8 D) C6H12O6 ® 2 C2H5OH + 2 CO 2 5. Given the balanced equation representing a reaction: ...
... A) CH 3COOH + CH3OH ® CH 3COOCH 3 + H 2O B) C2H6 + Cl 2 ® C2H5Cl + HCl C) C3H 6 + H2 ® C3H 8 D) C6H12O6 ® 2 C2H5OH + 2 CO 2 5. Given the balanced equation representing a reaction: ...
Organic Reactions
... Ability to distinguish reactants and products in a reaction Naming and identifying organic compounds Ability to distinguishing between saturated and unsaturated hydrocarbons Naming and recognizing functional groups in organic compounds ...
... Ability to distinguish reactants and products in a reaction Naming and identifying organic compounds Ability to distinguishing between saturated and unsaturated hydrocarbons Naming and recognizing functional groups in organic compounds ...
Microsoft Word - Final Exam Study Guide
... alcohols/ethers/epoxides, multistep synthesis, protecting groups, redox reactions, reagents for redox reactions, Grignard reaction 1. Mechanisms. These are the very basic types of mechanisms. You should also be able to explain regiochemistry and stereochemistry outcomes, as well as rearrangements, e ...
... alcohols/ethers/epoxides, multistep synthesis, protecting groups, redox reactions, reagents for redox reactions, Grignard reaction 1. Mechanisms. These are the very basic types of mechanisms. You should also be able to explain regiochemistry and stereochemistry outcomes, as well as rearrangements, e ...
Diels–Alder reaction
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The Diels–Alder reaction is an organic chemical reaction (specifically, a [4+2] cycloaddition) between a conjugated diene and a substituted alkene, commonly termed the dienophile, to form a substituted cyclohexene system. It was first described by Otto Paul Hermann Diels and Kurt Alder in 1928, for which work they were awarded the Nobel Prize in Chemistry in 1950. The Diels–Alder reaction is particularly useful in synthetic organic chemistry as a reliable method for forming 6-membered systems with good control over regio- and stereochemical properties. The underlying concept has also been applied to other π-systems, such as carbonyls and imines, to furnish the corresponding heterocycles, known as the hetero-Diels–Alder reaction. Diels–Alder reactions can be reversible under certain conditions; the reverse reaction is known as the retro-Diels–Alder reaction.