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Essay — Diet and disease
Essay — Diet and disease

... we are commonly bombarded with a plethora of information regarding the many diseases and health problems that we as human beings are prone to develop. With these many sources of information we are given multiple opinions, warnings, guidelines and suggestions as how to ward off these illnesses that a ...
Familial Cancer Service Guide
Familial Cancer Service Guide

... with a personal and/or family history of cancer. We provide surveillance recommendations and may offer genetic testing where appropriate. Categories for Appointment Clinical description ...
A Randomised Phase III Trial To Determine The Role Of Fdg – Pet
A Randomised Phase III Trial To Determine The Role Of Fdg – Pet

... docetaxel for patients with ER- PR- HER2- advanced breast cancer (also available in Altnagelvin) POETIC Trial of Perioperative Endocrine Therapy - Individualising Care (also available in Craigavon and Ulster Hospital) RETROSPECTIVE TNT A translational research study investigating different gene expr ...
PT3 prostate cancer
PT3 prostate cancer

... As a result of these selection criteria, patients in the erMRI group had almost twice the rate of pT3/4 (39%) than previous studies, which typically have a locally-advanced rate of approximately 20% [15,17]. Given these selection criteria for erMRI and the subsequent high rate of locally advanced di ...
How to pass the test
How to pass the test

...  Population – a collection of individuals who share a common trait  Sample – selection of individuals from that population  Sample size – contributes to the precision of the estimate  Bias – trend in the collection, analysis, interpretation, publication, or review of data that can lead to conclu ...
TGF-β signaling dictates therapeutic targeting in prostate cancer
TGF-β signaling dictates therapeutic targeting in prostate cancer

... to tumorigenesis due to either loss of expression or mutational inactivation of its membrane receptors or intracellular effectors, the Smads [7]. In advanced cancer, TGF-β promotes tumor progression and metastasis via induction of tumor-cell invasion, angiogenesis and immunosuppression [12,13]. By v ...
act_of_observation_tifr1
act_of_observation_tifr1

... 1. Breast Cancer 8 trials : Early excess mortality in all trials 2. Lung Cancer 6 trials : Early excess mortality in all trials 3. Cervical Cancer Early excess mortality in VIA vs awareness 4. Prostate Cancer ...
WHAT IS CANCER?
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Understanding the PSA test A guide for men concerned about
Understanding the PSA test A guide for men concerned about

... Normally the growth of all cells is carefully controlled in the body. As cells grow old and die, new cells take their place. Cancer can develop when cells start to grow in an uncontrolled way. If this happens in your prostate, you may get prostate cancer. Prostate cancer is the most common cancer in ...
World Cancer Day Newsletter - UNON Joint Medical Service
World Cancer Day Newsletter - UNON Joint Medical Service

... any new growth on the skin, or patches of skin that bleed, itch or become red Having any of these signs doesn’t always mean that you have cancer. They may be due to some other medical problem, or they may not be serious at all. Only your doctor can tell for sure. E. What is the role of Joint Medical ...
An Evaluation of Patient Preferences for the Treatment of Localized
An Evaluation of Patient Preferences for the Treatment of Localized

... prostate cancer mortality for the PSA screened population compared to active surveillance within 10-15 years is unknown and subject to long-term randomised controlled trials. The recent European screening study demonstrated a reduction in prostate cancer specific mortality from PSA screening and tre ...
Management of prostate cancer in older men: recommendations of a
Management of prostate cancer in older men: recommendations of a

... various treatments. A commonly used tool is that developed by D’Amico et al. [23] to evaluate the probability of biochemical relapse at 5 years after curative therapy. Patients are classified into three risk groups (low, medium, and high) based on biopsy Gleason score, preoperative PSA level and ...
Linköping University Post Print Molecular sampling of prostate cancer: a
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... Based on how far the cancer has progressed & its location in the body it responds differently to treatment. A cancer specialist called an Oncologist will provide the patient with the best treatment plan based on the form of cancer and how aggressive the cancer ...
The Basics of Oncology
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The Impact of 5α-Reductase Inhibition on Prostate Cancer (Review)
The Impact of 5α-Reductase Inhibition on Prostate Cancer (Review)

... detection in biopsies on patients in the treatment arms of each study and inherent selection biases in both studies. The fact that a large number of patients in the PCPT were not included in the final analysis for various reasons requires serious consideration. In the finasteride group, 3,290/8,137 ...
عرض تقديمي من PowerPoint
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CENTRAL NEW ZEALAND CANCER CONTROL NETWORK
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... to succeed and meet our expectations we will need to fundraise more. Our first target is to obtain funding for a national meeting next year. Sausage sizzles on the way! But on a serious note we will be making applications to secure this funding from Trusts etc. National View of Cancer Steve Creed. M ...
Chemoprevention of carcinoma prostate. A review
Chemoprevention of carcinoma prostate. A review

... and studied the biology of the prostate cancer. An attempt is made to identify intermediate markers and surrogate endpoint markers. The various interventions and initial clinical trial results are described. End points for evaluation are mainly based on changes in PSA, changes of histological precur ...
Tumor markers What are tumor markers?
Tumor markers What are tumor markers?

... This can sometimes detect cancer recurrence before the woman has symptoms or evidence of cancer on imaging tests. Many doctors question the test's value, though, because no one has shown a long-term advantage in finding recurrent breast cancer early. ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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