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High-grade prostatic intraepithelial neoplasia and - HAL
High-grade prostatic intraepithelial neoplasia and - HAL

... according to pathological results. The minority of the patients (18%) had a abnormal DRE. The inclusion criterion was the use of a 21-core extended biopsy scheme: all the patients underwent a 21core biopsy protocol for the initial and the repeated biopsies. The 21-core biopsy protocol was previously ...
Cancer Awareness
Cancer Awareness

... • GPs have limited time with patients and continuity of care is less common nowadays - patients often have a relationship with a practice rather than a doctor. • Patients often wait to be prompted by the doctor before discussing certain symptoms. • GPs often say that patients will wait until the end ...
global trends in cancer: developing countries need more focus
global trends in cancer: developing countries need more focus

DRUG NAME: Leuprolide
DRUG NAME: Leuprolide

67) CANCER SCREENING What is cancer screening? —Cancer
67) CANCER SCREENING What is cancer screening? —Cancer

... is to find those cancers that can be found as early as possible, before a person has any symptoms. Different tests can be used to screen for different types of cancers. The age at which screening starts varies depending on the type of cancer being screened for. That’s because different cancers tend ...
Detection of Prostate Cancer and Predicting Progression: Current
Detection of Prostate Cancer and Predicting Progression: Current

... Diagnostics Research Branch, Cancer Diagnosis Program, National Cancer Institute, Rockville, Maryland; 2Aerodigestive Clinical Cancer Research Section, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and 3The EMMES Corporation, ...
Review
Review

http://www.hopkinsmedicine.org/howard_county_general_hospital/_downloads/wellness/WellnessMattersFall2014.pdf
http://www.hopkinsmedicine.org/howard_county_general_hospital/_downloads/wellness/WellnessMattersFall2014.pdf

Cancer - plaza
Cancer - plaza

Brachytherapy for Oncolgic Indications
Brachytherapy for Oncolgic Indications

... Request is for permanent radioactive seed implantation for prostate cancer with or without EBRT Request is for high dose rate (HDR) brachytherapy, a temporary seed implantation, for locally advanced prostate cancer (T1C, PSA > 10, T2/T3) Other: Request is for brachytherapy as part of combination the ...
Cancer - Cloudfront.net
Cancer - Cloudfront.net

Differentially Expressed Genes in Androgen
Differentially Expressed Genes in Androgen

... opment of hormone-refractory disease. The background of this clini cal phenomenon is poorly understood (4, 5). The transition from hormone-dependent to hormone-independent tumorigenesis is sup posed to be a cascade of genetic alterations caused by activation of oncogenes and/or inactivation of tumor ...
Advanced prostate cancer - Prostate Cancer Foundation of New
Advanced prostate cancer - Prostate Cancer Foundation of New

... of the following tests. You may not have needed to have all of the tests described here. ...
Lamees Alafeishat
Lamees Alafeishat

CURRENT ROLE OF SURGERY FOR HIGH RISK PROSTATE
CURRENT ROLE OF SURGERY FOR HIGH RISK PROSTATE

... markedly higher PCa death rate compared with those patients with a lower score (8,9). In a retrospective analysis of 751 men with non-metastatic PCa treated with RP, the cumulative incidence of PCa death within 20 years was 36-43% for men with GS of 8 to 10 compared with 10-13%, 15-19% and 29-35%, f ...
Press Advisory - Pancreatic Cancer Canada
Press Advisory - Pancreatic Cancer Canada

... One-day campaign aims to raise awareness about the only major cancer with a five-year survival rate in the single digits XXXXX (ADD CITY) (November XX) – The third annual one-day campaign to raise awareness about pancreatic cancer and create hope for those fighting the deadly disease is Thursday, No ...
O u t c o m e s - B...
O u t c o m e s - B...

Navigator Notes
Navigator Notes

... face-to-face support group for prostate cancer patients and their families. Call 1-800-227-2345 for locations. • The American Cancer Society’s I Can Cope is an educational program for people facing cancer that offers information and answers to many cancer topics through community classes, as well as ...
Early Detection and Treatment of Prostate Cancer
Early Detection and Treatment of Prostate Cancer

... level. For PSA levels between 4 and 10 ng/mL, the positive predictive value is 21%; this value increases to between 42% and 64% for PSA levels greater than 10 ng/mL. The positive predictive value appears to be independent of age, suggesting that increased disease prevalence is balanced by decreased ...
Prevention and Early Detection
Prevention and Early Detection

... Prostate cancer is the second leading cause of death in men, second only to lung cancer. While 1 man in 6 will get prostate cancer during his lifetime, only 1 man in 33 will die of this disease. 65% of prostate cancer cases are diagnosed in men 65 and older. African American men are at higher risk. ...
Modulation of Androgen and Progesterone Receptors by
Modulation of Androgen and Progesterone Receptors by

... natural compounds can affect signal transduction pathways, cell proliferation rates and cell differentiation and many of these compounds have hormone-like, antioxidant and antimutagenic activity. Some of these compounds may have potential for cancer prevention or even cancer therapy (12,23-25). We h ...
The influence of family history on prostate cancer risk
The influence of family history on prostate cancer risk

... USA, where PSA level testing and subsequent biopsy has become widespread, have shown that the lifetime probability of a man being diagnosed with invasive prostate cancer is 15.9% (1 in 6) [2]. Given the high incidence and mortality associated with the disease, ...
A to Z of medical words - Prostate Cancer Foundation of New Zealand
A to Z of medical words - Prostate Cancer Foundation of New Zealand

... different doses of radiation to different parts of the area being treated. This can help to reduce the dose given to healthy tissues surrounding the prostate gland and the risk of side effects. See also 3D conformal radiotherapy. Tool Kit fact sheet - External beam radiotherapy. ...
Are We Truly winning the War On Cancer?
Are We Truly winning the War On Cancer?

...  60% of patients die within the first year after diagnosis.  15% of patients only survive up to 5 years. ...
The Role of Calpain in the Proteolytic Cleavage of E
The Role of Calpain in the Proteolytic Cleavage of E

... stably transfected into SKBR3 cells and protein extracts harvested at the indicated times following TPA treatment.SKBR3-Ecad wild type cells are also shown (lane 10). Conclusion :1、Mutation of the E-cadherin Cytoplasmic Domain Inhibits Truncation of E-cadherin in Vivo ;2、amino acid residues 782-787 ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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