Androgen Receptor Splice Variants in Prostate Cancer
... important roles in prostate cancer initiation, progression as well as epithelial-to-mesenchymal transition (EMT). Several studies also demonstrated that AR-Vs could facilitate resistance to ADT and other non-AR-targeted therapies. But the significance of ARVs in the clinical setting remains somewhat ...
... important roles in prostate cancer initiation, progression as well as epithelial-to-mesenchymal transition (EMT). Several studies also demonstrated that AR-Vs could facilitate resistance to ADT and other non-AR-targeted therapies. But the significance of ARVs in the clinical setting remains somewhat ...
Spectral Polarization Imaging of Human Prostate Cancer Tissue
... properties of diseased and healthy human tissues has been reported in some studies using fluorescence and absorption (3, 4). The most attractive advantage of optical imaging is the high sensitivity, which can be superior to other in vivo imaging techniques (2). Over the past decade, cyanine dyes hav ...
... properties of diseased and healthy human tissues has been reported in some studies using fluorescence and absorption (3, 4). The most attractive advantage of optical imaging is the high sensitivity, which can be superior to other in vivo imaging techniques (2). Over the past decade, cyanine dyes hav ...
Gene Therapy for Prostate Cancer by Controlling
... temporary and inevitably the disease progresses to an androgenindependent state. Currently, no curative therapy is available for androgen-independent prostate cancers. Gene therapy provides an attractive opportunity to target androgen-independent prostate cancer. Unlike traditional chemotherapy, it ...
... temporary and inevitably the disease progresses to an androgenindependent state. Currently, no curative therapy is available for androgen-independent prostate cancers. Gene therapy provides an attractive opportunity to target androgen-independent prostate cancer. Unlike traditional chemotherapy, it ...
Diffusion tensor imaging of the normal prostate at 3 Tesla
... noma using 3-Tesla system. They used DTI sequences with b=0-700 mm/s. Tumoral foci were found to have higher FA values (0.24±0.05) when compared with the normal appearing peripheral gland (0.16±0.06). The FA values they have found in the peripheral gland is similar to our study. Haker et al. [19] in ...
... noma using 3-Tesla system. They used DTI sequences with b=0-700 mm/s. Tumoral foci were found to have higher FA values (0.24±0.05) when compared with the normal appearing peripheral gland (0.16±0.06). The FA values they have found in the peripheral gland is similar to our study. Haker et al. [19] in ...
Sample Letter to the Editor Dear Editor: Bladder cancer is the fifth
... the most expensive cancer to treat on a per patient basis. It is estimated that $2.9 billion is spent in the US each year on the treatment of bladder cancer. On Saturday, May 5th, we are walking for bladder cancer. We hope everyone can join us at [Location] to walk to raise awareness of the disease, ...
... the most expensive cancer to treat on a per patient basis. It is estimated that $2.9 billion is spent in the US each year on the treatment of bladder cancer. On Saturday, May 5th, we are walking for bladder cancer. We hope everyone can join us at [Location] to walk to raise awareness of the disease, ...
Rahrmann et al. Cancer Research - Interdepartmental Genetics
... cancer and is one of the leading causes of male cancer death (6). Before the development of invasive adenocarcinoma, several histologic abnormalities can sometimes be observed that are considered potential precursor lesions for prostatic adenocarcinoma. These include prostatic intraepithelial neopla ...
... cancer and is one of the leading causes of male cancer death (6). Before the development of invasive adenocarcinoma, several histologic abnormalities can sometimes be observed that are considered potential precursor lesions for prostatic adenocarcinoma. These include prostatic intraepithelial neopla ...
Know your prostate A guide to common prostate problems
... Inside every cell of our body is a set of instructions called genes. These are inherited from our parents. Genes control how the body grows, works and what it looks like. If something goes wrong with one or more genes (known as a fault or mutation) it can sometimes cause cancer. • You are two and a ...
... Inside every cell of our body is a set of instructions called genes. These are inherited from our parents. Genes control how the body grows, works and what it looks like. If something goes wrong with one or more genes (known as a fault or mutation) it can sometimes cause cancer. • You are two and a ...
MicroRNA Expression Profiles in Prostate Cancer Cell Lines
... cell lines and normal prostate cell lines was compared, eighteen miRNAs in the array were up-modulated and 18 showed lower levels of expression in at least 2 of 3 cancer cell lines. Three out of thirty-six differentially expressed miRNAs was not reported to be deregulated in cancer so far. Most of t ...
... cell lines and normal prostate cell lines was compared, eighteen miRNAs in the array were up-modulated and 18 showed lower levels of expression in at least 2 of 3 cancer cell lines. Three out of thirty-six differentially expressed miRNAs was not reported to be deregulated in cancer so far. Most of t ...
playing with numbers - Meridian Kinesiology
... Prostate cancer deaths have also declined since 1990, but here the reasons are even less clear. I think it is premature to declare that this decline is due to more widespread screening or to more effective treatments. In fact, a recent large study concluded that screening men for elevated levels of ...
... Prostate cancer deaths have also declined since 1990, but here the reasons are even less clear. I think it is premature to declare that this decline is due to more widespread screening or to more effective treatments. In fact, a recent large study concluded that screening men for elevated levels of ...
Human Prostate Cancer Cell Lines
... human prostatic epithelial cell lines, which express functional characteristics of prostatic epithelial cells, provide additional in vitro cell models for studies on prostatic neoplasia. (These are described in more detail elsewhere in this volume.) Researchers have immortalized cells (see Tables 1 ...
... human prostatic epithelial cell lines, which express functional characteristics of prostatic epithelial cells, provide additional in vitro cell models for studies on prostatic neoplasia. (These are described in more detail elsewhere in this volume.) Researchers have immortalized cells (see Tables 1 ...
Explaining the Race Difference in Prostate Cancer Stage at Diagnosis
... stage, but only 32% among men with distant stage disease (1). In an analysis of National Cancer Institute Surveillance, Epidemiology and End Results (SEER) data (4), later stage at diagnosis had the largest impact on explaining the Black-White difference in prostate cancer mortality. Although there ...
... stage, but only 32% among men with distant stage disease (1). In an analysis of National Cancer Institute Surveillance, Epidemiology and End Results (SEER) data (4), later stage at diagnosis had the largest impact on explaining the Black-White difference in prostate cancer mortality. Although there ...
MOD_REV02_MOSES
... cancer suspicion is typically based on an elevated prostate-specific antigen (PSA) level or on a suspicious node found during a digital rectal exam (DRE). More than half of all cancers detected today are not palpable, and PSA and DRE screenings have high falsepositive rates in general clinical pract ...
... cancer suspicion is typically based on an elevated prostate-specific antigen (PSA) level or on a suspicious node found during a digital rectal exam (DRE). More than half of all cancers detected today are not palpable, and PSA and DRE screenings have high falsepositive rates in general clinical pract ...
Nutrients in the Chemoprevention of Prostate Cancer: Current and
... ported in a recent study by Yoshizawa et al.49 They suggest a 50% to 66% reduction in risk for advanced cancer in men with the highest selenium status as determined by the level of selenium in toenails. Other potential antitumorigenic mechanisms of selenium are an apoptosis inducer, amino acid meta ...
... ported in a recent study by Yoshizawa et al.49 They suggest a 50% to 66% reduction in risk for advanced cancer in men with the highest selenium status as determined by the level of selenium in toenails. Other potential antitumorigenic mechanisms of selenium are an apoptosis inducer, amino acid meta ...
Identification of Differentially Expressed Proteins from Prostate
... Prostate cancer (PCa) is the most common cancer diagnosis and the second leading cause of cancer-related deaths in males worldwide. Prostate-specific antigen (PSA) is the only biomarker widely utilized in diagnosis and management of PCa patients. However, PSA lacks sensitivity and specificity for di ...
... Prostate cancer (PCa) is the most common cancer diagnosis and the second leading cause of cancer-related deaths in males worldwide. Prostate-specific antigen (PSA) is the only biomarker widely utilized in diagnosis and management of PCa patients. However, PSA lacks sensitivity and specificity for di ...
Treatment strategies for high-risk locally advanced prostate cancer
... cancer progression. For example, a prediagnosis Psa velocity of >2 ng/ml/year has been shown to increase the likelihood of death from prostate cancer after either radical prostatectomy or external beam radiation therapy.20,21 Psa doubling time22,23 and the volume of cancer at initial diagnosis (as a ...
... cancer progression. For example, a prediagnosis Psa velocity of >2 ng/ml/year has been shown to increase the likelihood of death from prostate cancer after either radical prostatectomy or external beam radiation therapy.20,21 Psa doubling time22,23 and the volume of cancer at initial diagnosis (as a ...
Cancer Slides
... Findings • According to research published by the NCIN in June 2009, as many as 15,000 people aged 75 and over die prematurely from cancer each year. • In general, older people with cancer receive less intensive and less radical treatment than younger people. While some older people may in general ...
... Findings • According to research published by the NCIN in June 2009, as many as 15,000 people aged 75 and over die prematurely from cancer each year. • In general, older people with cancer receive less intensive and less radical treatment than younger people. While some older people may in general ...
Diagnosing localised prostate cancer
... be regularly monitored and if symptoms develop (e.g. bone pain), treatment will be offered to manage these symptoms. The intent is to treat symptoms as they arise. • Active surveillance: For men who have low-risk prostate cancer, active surveillance is an option. Men are regularly monitored by the ...
... be regularly monitored and if symptoms develop (e.g. bone pain), treatment will be offered to manage these symptoms. The intent is to treat symptoms as they arise. • Active surveillance: For men who have low-risk prostate cancer, active surveillance is an option. Men are regularly monitored by the ...
13040_2017_129_MOESM1_ESM
... It is important that a disease specific AVS is matched with a genomic region specific to that disease. The enrichment of an AVS in a particular genomic feature could be cell specific. To validate the cell specificity, we tested the enrichment of each cancer type AVS in the respective most enriched r ...
... It is important that a disease specific AVS is matched with a genomic region specific to that disease. The enrichment of an AVS in a particular genomic feature could be cell specific. To validate the cell specificity, we tested the enrichment of each cancer type AVS in the respective most enriched r ...