Exploring the Biosynthetic Potential of Cystobacter fuscus
... im letzten Jahr meiner Arbeit. Bei Katrin Jungmann und Hilda Sucipto für das Beantworten meiner vielen Fragen rund um die Molekularbiologie sowie bei Dr. Thomas Hoffmann, der mir von Anfang an immer mit Rat und Tat zur Seite stand. Außerdem bei ...
... im letzten Jahr meiner Arbeit. Bei Katrin Jungmann und Hilda Sucipto für das Beantworten meiner vielen Fragen rund um die Molekularbiologie sowie bei Dr. Thomas Hoffmann, der mir von Anfang an immer mit Rat und Tat zur Seite stand. Außerdem bei ...
Determination of the pKa of the N-terminal amino group of
... The modification of proteins with polyubiquitin chains has profound consequences for their behaviour and can target proteins to the proteasome for degradation, activate signalling cascades or regulate the DNA damage response amongst many other functions. The fate of the modified protein depends on t ...
... The modification of proteins with polyubiquitin chains has profound consequences for their behaviour and can target proteins to the proteasome for degradation, activate signalling cascades or regulate the DNA damage response amongst many other functions. The fate of the modified protein depends on t ...
ASPECTS OF ANAEROBIC METABOLISM IN
... step. Instead, pyruvate will be carboxylated to oxaloacetate or to malate. The latter alternative appears the more probable, as this reductive carboxylation could take place in the cytosol, thus ensuring cytoplasmic redox balance. Following transportation into the mitochondria malate would undergo d ...
... step. Instead, pyruvate will be carboxylated to oxaloacetate or to malate. The latter alternative appears the more probable, as this reductive carboxylation could take place in the cytosol, thus ensuring cytoplasmic redox balance. Following transportation into the mitochondria malate would undergo d ...
- World Journal of Gastroenterology
... cellular damage was published in 1955 by Molander and colleagues, after noticing that the levels of glutamic oxalacetic transaminase (GOT or AST) were elevated after acute myocardial infarction[2]. It is noteworthy to mention that high serum GOT activity observed in patients with myocardial infarcti ...
... cellular damage was published in 1955 by Molander and colleagues, after noticing that the levels of glutamic oxalacetic transaminase (GOT or AST) were elevated after acute myocardial infarction[2]. It is noteworthy to mention that high serum GOT activity observed in patients with myocardial infarcti ...
The intertwined metabolism of Medicago truncatula and its nitrogen
... its functional properties. The numerous possible theoretical investigations (Rezola et al., 2015) are for example ...
... its functional properties. The numerous possible theoretical investigations (Rezola et al., 2015) are for example ...
Mixotrophic and photoheterotrophic metabolism in
... derivatives and organic acids from central metabolic pathways, respectively) on Cyanothece 51142 growth and metabolism. Two nitrogen sources other than N2, ammonia and nitrate, were also examined. Precise readouts of metabolic state and activity were based on 13C-assisted metabolite analysis integra ...
... derivatives and organic acids from central metabolic pathways, respectively) on Cyanothece 51142 growth and metabolism. Two nitrogen sources other than N2, ammonia and nitrate, were also examined. Precise readouts of metabolic state and activity were based on 13C-assisted metabolite analysis integra ...
Functional lipidomics of oxidized products from polyunsaturated fatty
... We have been interested in hydroxy-alkenals that may be issued from the whole series of omega-3 or omega-6 PUFA, in contrast to isoprostanes and neuroprostanes that are products of ARA and DHA only. In that case, 4-hydroxy-hexenal (4-HHE) and 4-hydroxy-nonenal (4-HNE) are indices of omega-3 and ome ...
... We have been interested in hydroxy-alkenals that may be issued from the whole series of omega-3 or omega-6 PUFA, in contrast to isoprostanes and neuroprostanes that are products of ARA and DHA only. In that case, 4-hydroxy-hexenal (4-HHE) and 4-hydroxy-nonenal (4-HNE) are indices of omega-3 and ome ...
Iboga – mit in resničnost
... effects last longer than the presence of ibogaine in the body fat deposits of lipophillic metabolite cannot directly cause the effect for weeks or months ...
... effects last longer than the presence of ibogaine in the body fat deposits of lipophillic metabolite cannot directly cause the effect for weeks or months ...
Probing the Performance Limits of the Escherichia
... coli from a metabolic database encompassing many genes from multiple species. The resulting pathways need not lie directly on main production pathways, as they may enhance production indirectly by either redirecting metabolic fluxes into the production pathways or by increasing the energy efficiency ...
... coli from a metabolic database encompassing many genes from multiple species. The resulting pathways need not lie directly on main production pathways, as they may enhance production indirectly by either redirecting metabolic fluxes into the production pathways or by increasing the energy efficiency ...
Synthesis and thermal decarbonylation of W(CO)5 complexes
... E-mail address: [email protected] (G.A. Carriedo). ...
... E-mail address: [email protected] (G.A. Carriedo). ...
Supplementary File
... indicating perfect separation. For almost 0 separation, the weights assigned to different genes were very similar for the two models. This suggested that essentially a single model would fit the entire data. For some sets of λ and τ a large separation was achieved. This suggests that one of the two ...
... indicating perfect separation. For almost 0 separation, the weights assigned to different genes were very similar for the two models. This suggested that essentially a single model would fit the entire data. For some sets of λ and τ a large separation was achieved. This suggests that one of the two ...
13C-fluxomics
... e.g. E. coli grown on glucose: 253 isotopic data • 57 LC-MS/MS data • 63 GC-MSdata • 133 NMR data ...
... e.g. E. coli grown on glucose: 253 isotopic data • 57 LC-MS/MS data • 63 GC-MSdata • 133 NMR data ...
Basal Metabolic Rate
... Discover a Unifying Principle in Metabolism.” In his classic review, Hemmingsen (1960) showed that when expressed at a constant temperature, the SMR of different-sized multicellular ectotherms was related to essentially the same power function of body mass as endothermic mammals and birds but at a l ...
... Discover a Unifying Principle in Metabolism.” In his classic review, Hemmingsen (1960) showed that when expressed at a constant temperature, the SMR of different-sized multicellular ectotherms was related to essentially the same power function of body mass as endothermic mammals and birds but at a l ...
Metabolomics based gene function annotation in Escherichia coli
... accessions/strains, tissues, and cell types of an organism. Once the metabolic diversity has been described, the genetic-basis for the metabolic and/or phenotypic differences can be elucidated using other omics technologies such genomics, transcriptomics, and proteomics. In both strategies, the gene ...
... accessions/strains, tissues, and cell types of an organism. Once the metabolic diversity has been described, the genetic-basis for the metabolic and/or phenotypic differences can be elucidated using other omics technologies such genomics, transcriptomics, and proteomics. In both strategies, the gene ...
Fragmentation pathway for glutamine identification: Loss of 73 da
... dissociation (CID), which results in the loss of butyl formate (102 Da) as a neutral molecule from most of derivatized amino acids, enabling sensitive analysis [1]. The quantification of amino acids can be achieved by adding deuterium labeled amino acids as internal standards. Johnson [13]°improved° ...
... dissociation (CID), which results in the loss of butyl formate (102 Da) as a neutral molecule from most of derivatized amino acids, enabling sensitive analysis [1]. The quantification of amino acids can be achieved by adding deuterium labeled amino acids as internal standards. Johnson [13]°improved° ...
Capillary electrophoresis tandem mass spectrometry of bromine
... (NYITR-NH2 ) was allowed to react with DBEP. Brominecontaining ions (291/293 m/z) appeared again in the MS/MS spectrum together with a 70 m/z ion (immonium ion of N) and a series of *b ions (832, 676, 576, 463 m/z corresponding to labeled NYITR, NYIT, NYI, NY sequences) along with a series of *a ion ...
... (NYITR-NH2 ) was allowed to react with DBEP. Brominecontaining ions (291/293 m/z) appeared again in the MS/MS spectrum together with a 70 m/z ion (immonium ion of N) and a series of *b ions (832, 676, 576, 463 m/z corresponding to labeled NYITR, NYIT, NYI, NY sequences) along with a series of *a ion ...
Detoxification mechanisms (Apis mellifera) resulting in tolerance of dietary nicotine
... nicotine-sensitive aphids which showed 100% mortality after only six days on a diet containing 30 ppm nicotine22, honey bees tolerated 50 ppm nicotine in their diet during 21 day survival studies29 (honey bee LC50 = 2000 ppm26). In the insect species that have adapted to nicotine-producing plants, ...
... nicotine-sensitive aphids which showed 100% mortality after only six days on a diet containing 30 ppm nicotine22, honey bees tolerated 50 ppm nicotine in their diet during 21 day survival studies29 (honey bee LC50 = 2000 ppm26). In the insect species that have adapted to nicotine-producing plants, ...
![[U-13C]propionate, phenylacetate, and acetaminophen](http://s1.studyres.com/store/data/002254284_1-9ecb94e9c5e6c14c57ae26d63989e9aa-300x300.png)
[U-13C]propionate, phenylacetate, and acetaminophen
... Most common tracers of hepatic metabolism, such as the gluconeogenic substrates lactate and alanine, may be metabolized to some extent by peripheral tissues and thus possibly confound analysis of liver metabolism. Ideally, any tracer should be infused directly into the hepatic portal vein and extrac ...
... Most common tracers of hepatic metabolism, such as the gluconeogenic substrates lactate and alanine, may be metabolized to some extent by peripheral tissues and thus possibly confound analysis of liver metabolism. Ideally, any tracer should be infused directly into the hepatic portal vein and extrac ...
The Metabolic Network of Synechocystis sp. PCC
... allows the prediction of optimal steady-state fluxes that maximize a given objective function, usually the synthesis of biomass or biomass precursors required for growth. Although certainly not without pitfalls, the predictions of FBA have proven to reasonably reflect the modes of cellular operation ...
... allows the prediction of optimal steady-state fluxes that maximize a given objective function, usually the synthesis of biomass or biomass precursors required for growth. Although certainly not without pitfalls, the predictions of FBA have proven to reasonably reflect the modes of cellular operation ...
High Coverage Process Specific HCP Identification and
... • Data shown from two experiments comparing Biosimilars vs Innovators using either different manufacturing replicates (A) or lots (B). ...
... • Data shown from two experiments comparing Biosimilars vs Innovators using either different manufacturing replicates (A) or lots (B). ...
M-path: a compass for navigating potential metabolic pathways
... from the chemical structures of substrates and products in known enzymatic reactions and applied to produce possible metabolic pathways including putative compounds and enzymatic reactions. This approach can suggest previously unknown enzymatic reactions in synthetic metabolic pathways. However, the ...
... from the chemical structures of substrates and products in known enzymatic reactions and applied to produce possible metabolic pathways including putative compounds and enzymatic reactions. This approach can suggest previously unknown enzymatic reactions in synthetic metabolic pathways. However, the ...
Peroxisome Proliferator-Activated Receptor Activation is
... The animal experiments complied with the Guidelines for the Care and Use of Experimental Animal use and the study protocols were approved by the Norwegian State Board for Biological Experiments with Living animals (“Forsøksdyrutvalget”, permit number 2005140). 2.3. Biochemical Analyses With the exce ...
... The animal experiments complied with the Guidelines for the Care and Use of Experimental Animal use and the study protocols were approved by the Norwegian State Board for Biological Experiments with Living animals (“Forsøksdyrutvalget”, permit number 2005140). 2.3. Biochemical Analyses With the exce ...
Determination of De Novo Synthesized Amino Acids in Cellular
... C nuclear magnetic resonance spectroscopy was used to determine the absolute amounts of de novo synthesized amino acids in both the perchloric acid extracts and the hydrolyzed protein fractions of F98 glioma cells incubated for 2 h with 5 mmol/l [U-13C]glucose. 13C NMR spectra of the hydrolyzed prot ...
... C nuclear magnetic resonance spectroscopy was used to determine the absolute amounts of de novo synthesized amino acids in both the perchloric acid extracts and the hydrolyzed protein fractions of F98 glioma cells incubated for 2 h with 5 mmol/l [U-13C]glucose. 13C NMR spectra of the hydrolyzed prot ...
Extended Detail on Checklist items
... 4. Describe in detail the calculation of FDRs at the PSM, peptide, and protein levels. Describe which tools are used to estimate the false discovery rate (FDR) at the peptide-spectrum-match (PSM) level, at the distinct peptide sequence level, and at the protein level. Briefly describe the approach a ...
... 4. Describe in detail the calculation of FDRs at the PSM, peptide, and protein levels. Describe which tools are used to estimate the false discovery rate (FDR) at the peptide-spectrum-match (PSM) level, at the distinct peptide sequence level, and at the protein level. Briefly describe the approach a ...