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Viruses Living or Not
Viruses Living or Not

... on white blood cells. Thus, HIV will only infect white blood cells and not lung cells or other cell types. •Sometimes, a virus can mutate and change its host range. This appears to be happening with the avian flu virus (influenza A/H5N1) currently circulating. At first, the flu virus could infect on ...
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Lecture Outline
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Pathogen–host–environment interplay and disease emergence
Pathogen–host–environment interplay and disease emergence

... disease whose incidence is increasing following its first introduction into a new host population or whose incidence is increasing in an existing host population as a result of long-term changes in its underlying epidemiology’.1 EID events may also be caused by a pathogen expanding into an area in w ...
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Biology\Viruses, Bacteria, & Infectious Diseases
Biology\Viruses, Bacteria, & Infectious Diseases

... • Evaluate the effects of bacteria on humans, good and bad. • Predict the significance to health of the different stages of a viral or bacterial infection. • Design a controlled experiment using bacteria. • Research and identify illnesses/diseases and the organisms that cause them. • Discuss the imp ...
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Quantification of Foot-and-mouth Disease Virus Transmission Rates

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... Zoonoses have direct adverse effects on primates beyond the actual disease burden of morbidity and mortality. Reproductive productivity is also impacted. So, what to do? Some basic precautions appear reasonable. Increased separations of human and non-human primates, assurance of the health and vacci ...
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... Classically it was assumed that transmission rate increases with population size, because contacts increase with crowding. Æ mass action (βSI) was dominant transmission term Hethcote and others argued that rates of sexual contact are determined more by behaviour and social norms than by density, and ...
Bloodborne Pathogens
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The Basic Reproductive Number

... deterministic compartmental models. We describe that method here but omit the proofs. We consider a deterministic model for disease transmission with n compartments (dimensions). We denote the nonnegative orthant of Rn by R̄n+ . We let x(t) ∈ R̄n+ where xi (t) denotes the number of individuals in co ...
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Pathogens - Net Texts

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... Many bacteria employ some form of intercellular communication to alert pathogens about their collective bacterial concentration. If high concentrations are detected, pathogens can switch their transcription profiles to an invasive phenotype [5, 6]. An impressive array of natural and synthetic molecu ...
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07_Path___vir_Fact_path_I_2014

... Pathogenicity = the ability to cause a disease It depends on both microbial and host species Particular microbial species is pathogenic for a specific host species only, for another species it may be non-pathogenic This host species is susceptible to the relevant microbial species, to a different mi ...
Ecological Epidemiology - Princeton University Press
Ecological Epidemiology - Princeton University Press

... resemblances. One distinction that is useful is that between microparasites and macroparasites. Microparasites are small, often intracellular, and they mul­ tiply directly within their host where they are often extremely numerous. Hence, it is usually impossible to count the number of microparasites ...
Emerging zoonotic viruses: What characterizes them and what
Emerging zoonotic viruses: What characterizes them and what

... domestic animals and wildlife. Even though the majority of these infections only cause minor health problems, the relatively recent emergence of HIV clearly illustrates that the next major human pandemic may surface at any time. Regardless of what the name indicates, most emerging human pathogens ar ...
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Cross-species transmission

Cross-species transmission (CST) is the phenomenon of transfer of viral infection from one species, usually a similar species, to another. Often seen in emerging viruses where one species transfers to another which in turn transfers to humans. Examples include HIV-AIDS, SARS, Ebola, Swine flu, rabies, and Bird flu.The exact mechanism that facilitates the transfer is unknown, however, it is believed that viruses with a rapid mutation rate are able to overcome host-specific immunological defenses. This can occur between species that have high contact rates. It can also occur between species with low contact rates but usually through an intermediary species. Bats, for example, are mammals and can directly transfer rabies to humans through bite and also through aerosolization of bat salvia and urine which are then absorbed by human mucous membranes in the nose, mouth and eyes.Similarity between species, for example, transfer between mammals, is believed to be facilitated by similar immunological defenses. Other factors include geographic area, intraspecies behaviours, and phylogenetic relatedness. Virus emergence relies on two factors: initial infection and sustained transmission.
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