Bioaccumulation
... Since the 1980s the world amphibian population has declined and there has been an increase in birth deformities. This may be due to: drought, increased UV rays, pollution, habitat loss, parasites and diseases. Amphibians, like this frog, have exhibited drastic changes since the 1980s. ...
... Since the 1980s the world amphibian population has declined and there has been an increase in birth deformities. This may be due to: drought, increased UV rays, pollution, habitat loss, parasites and diseases. Amphibians, like this frog, have exhibited drastic changes since the 1980s. ...
Multi-component Ecosystem Model for SAB
... models • Models work independently? • Yes – implies little biological exchange been MAB and SAB • No – what is the nature of exchange and how can this be parameterized? • Logistics of implementing two different food web models in circulation model ...
... models • Models work independently? • Yes – implies little biological exchange been MAB and SAB • No – what is the nature of exchange and how can this be parameterized? • Logistics of implementing two different food web models in circulation model ...
Interactions Among Living Things
... 1. a type of symbiosis in which one organism live with, in, or on a host and harms it 2. the struggle between organisms to survive as they attempt to use the same limited resources in the same place at the same time 3. a type of symbiosis in which both species benefit from living together 4. the pro ...
... 1. a type of symbiosis in which one organism live with, in, or on a host and harms it 2. the struggle between organisms to survive as they attempt to use the same limited resources in the same place at the same time 3. a type of symbiosis in which both species benefit from living together 4. the pro ...
CNSDrugs - shabeelpn
... • Remember that it is the rate of action potential propagation that determines neurologic function. – Determined by frequency of action potentials. ...
... • Remember that it is the rate of action potential propagation that determines neurologic function. – Determined by frequency of action potentials. ...
lec#7 done by Lama Abusharaf
... which is important in prostaglandin synthesis Slide 7: 1-drugs may have receptors all over the body but selective drugs drugs have receptors in specific organs not all over the body and that may decrease the side effects of these drugs 2- No. of receptors should be reasonable in order to produce th ...
... which is important in prostaglandin synthesis Slide 7: 1-drugs may have receptors all over the body but selective drugs drugs have receptors in specific organs not all over the body and that may decrease the side effects of these drugs 2- No. of receptors should be reasonable in order to produce th ...
5HT1F- and 5HT7-Receptor Agonists for the Treatment of Migraines
... order of potencies for serotonergic ligands at this new receptor: 5-HT > sumatriptan >> 5-carboxyamidotryptamine > 8hydroxy-2(di-1-propylamino)tetralin > spiperone. 5-HT produced a dose-dependent inhibition of forskolin-stimulated cAMP accumulation (EC50 = 7.9 nM) in transfected cells. These propert ...
... order of potencies for serotonergic ligands at this new receptor: 5-HT > sumatriptan >> 5-carboxyamidotryptamine > 8hydroxy-2(di-1-propylamino)tetralin > spiperone. 5-HT produced a dose-dependent inhibition of forskolin-stimulated cAMP accumulation (EC50 = 7.9 nM) in transfected cells. These propert ...
Unit 5 Part 1: ECOLOGY KEY TERM`S DIRECTIONS: MATCH THE
... _________________A group of ecosystems in the same region having similar types of vegetation governed by similar climate ...
... _________________A group of ecosystems in the same region having similar types of vegetation governed by similar climate ...
Drugs and Treatments (1)
... Drugs/chemicals used in aquaculture • Chemicals (cont.) – Copper Sulfate (<6.4 mg copper/L water) – Also called Cutrine • Algaecide/bactericide/parasiticide • Effective on scaled fish, but can cause problems with scaleless fish (catfish). • Can produce kidney necrosis, destruction of hematopoietic ...
... Drugs/chemicals used in aquaculture • Chemicals (cont.) – Copper Sulfate (<6.4 mg copper/L water) – Also called Cutrine • Algaecide/bactericide/parasiticide • Effective on scaled fish, but can cause problems with scaleless fish (catfish). • Can produce kidney necrosis, destruction of hematopoietic ...
351 Pharmacology 3rd sf
... Drug Receptors Receptor/Binding site “A specific protein in either the plasma membrane or interior of a target cell with which a ligand/drug combines” It must be selective in choosing ligands/drugs to bind To avoid constant activation of the receptor by promiscuous binding of many different l ...
... Drug Receptors Receptor/Binding site “A specific protein in either the plasma membrane or interior of a target cell with which a ligand/drug combines” It must be selective in choosing ligands/drugs to bind To avoid constant activation of the receptor by promiscuous binding of many different l ...
AP Biology - Boone County Schools
... Why do individuals of the same species vary in how they look, function and behave? ...
... Why do individuals of the same species vary in how they look, function and behave? ...
Population responses
... Mixed antagonist: binds to separate site but modulates the ability of agonist to bind Physiological antagonist: a drug (or endogenous mediator) that antagonizes the effect of another drug (or endogenous mediator) by producing an opposing physiological response, typically by a different type of recep ...
... Mixed antagonist: binds to separate site but modulates the ability of agonist to bind Physiological antagonist: a drug (or endogenous mediator) that antagonizes the effect of another drug (or endogenous mediator) by producing an opposing physiological response, typically by a different type of recep ...
Climate modeling
... • Determine regional distribution of vegetation types within a given climate scenario Use a combination of mechanisms to develop model In general, disturbance regimes are not considered Examples: BIOME3, MAPSS and DOLLY Application to high latitude system In Simulation, the equilibrium response of v ...
... • Determine regional distribution of vegetation types within a given climate scenario Use a combination of mechanisms to develop model In general, disturbance regimes are not considered Examples: BIOME3, MAPSS and DOLLY Application to high latitude system In Simulation, the equilibrium response of v ...
Document
... • Systemic administration, short half life of ~ 2h • Topical ocular admin, longer half life. – Bind to iris pigments and are released over days ,darker irises bind more ...
... • Systemic administration, short half life of ~ 2h • Topical ocular admin, longer half life. – Bind to iris pigments and are released over days ,darker irises bind more ...
CNS Depressants/Antianxiety Agents
... Triazolam – t1/2 = 3 hr. b) Flurazepam – t1/2 = 74 hr. c) Temazepam (Restoril) – t1/2 = 11 hr. 2. Non-benzodiazepines that bind to the BZ1 site d) Zolpidem (Ambien) – t1/2 = 2 hr. e) Zaleplon (Sonata) – t1/2 = 1 hr. ...
... Triazolam – t1/2 = 3 hr. b) Flurazepam – t1/2 = 74 hr. c) Temazepam (Restoril) – t1/2 = 11 hr. 2. Non-benzodiazepines that bind to the BZ1 site d) Zolpidem (Ambien) – t1/2 = 2 hr. e) Zaleplon (Sonata) – t1/2 = 1 hr. ...
G-Protein Coupled Receptors Past, Present, Future Outline and
... receptive substances especially liable to change and capable of setting the chief substance in action. Further, that nicotine, curari, atropine, pilocarpine, strychnine, and most other alkaloids, as well as the effective material of internal secretions produce their effects by combining with the rec ...
... receptive substances especially liable to change and capable of setting the chief substance in action. Further, that nicotine, curari, atropine, pilocarpine, strychnine, and most other alkaloids, as well as the effective material of internal secretions produce their effects by combining with the rec ...
Ch 1-3 Envir
... Process that changes an organism to better suit their environment Those organisms with characteristics best suited for their environment will be successful Those poorly suited for their environment are less likely to reproduce or survive Over time poorly suited characteristics disappear from the pop ...
... Process that changes an organism to better suit their environment Those organisms with characteristics best suited for their environment will be successful Those poorly suited for their environment are less likely to reproduce or survive Over time poorly suited characteristics disappear from the pop ...
教案- Pharmacologic Management of Parkinsonism
... Multimedia and writing on the blackboard design elements: the use of drugs in various dosage forms show powerpoint software to guide students into this new discipline, for some preliminary understanding a few basic concepts to master. ...
... Multimedia and writing on the blackboard design elements: the use of drugs in various dosage forms show powerpoint software to guide students into this new discipline, for some preliminary understanding a few basic concepts to master. ...
Capsicum
... neurogenic inflammation In the CNS, stimulation of 5-HT1D receptors results in inhibition of pain transmission, another mode of action that may be involved in the abortive treatment of migraine ...
... neurogenic inflammation In the CNS, stimulation of 5-HT1D receptors results in inhibition of pain transmission, another mode of action that may be involved in the abortive treatment of migraine ...
Desalination as a Health Hazard
... CDC Third National Report on Human Exposure to Environmental Exposure to Environmental Chemicals-2005) Other studies have shown the same chemicals in human cord blood (trans-placental fetal contamination) , and maternal milk. The levels of these chemicals found in the bodies of the American public h ...
... CDC Third National Report on Human Exposure to Environmental Exposure to Environmental Chemicals-2005) Other studies have shown the same chemicals in human cord blood (trans-placental fetal contamination) , and maternal milk. The levels of these chemicals found in the bodies of the American public h ...
2nd Lecture 1433
... present in the body. The antagonist binds to the receptor but does not trigger the cell’s response” For Example, atropine is a muscarinic receptor antagonist because it can bind to muscarinic receptors but it does not trigger the cell’s response. In this way, it prevents binding of acetylcholine ( ...
... present in the body. The antagonist binds to the receptor but does not trigger the cell’s response” For Example, atropine is a muscarinic receptor antagonist because it can bind to muscarinic receptors but it does not trigger the cell’s response. In this way, it prevents binding of acetylcholine ( ...
Alkylating agents
... • MTX is a folic acid analog that binds with high affinity to the active catalytic site of dihydrofolate reductase (DHFR) • Thus it interferes with the synthesis of tetrahydrofolate (THF) • THF serves as the key one-carbon carrier for enzymatic processes involved in de novo synthesis of thymidylate, ...
... • MTX is a folic acid analog that binds with high affinity to the active catalytic site of dihydrofolate reductase (DHFR) • Thus it interferes with the synthesis of tetrahydrofolate (THF) • THF serves as the key one-carbon carrier for enzymatic processes involved in de novo synthesis of thymidylate, ...
Ecology Review - KEY
... in the body for decades. When salmon eat the small fish, the PCBs become further concentrated in the salmon tissue, and when orcas eat the salmon the PCBs accumulate in the blubber. When the orca burns the fat for energy, the PCBs are released into the orca’s system, causing harm. ...
... in the body for decades. When salmon eat the small fish, the PCBs become further concentrated in the salmon tissue, and when orcas eat the salmon the PCBs accumulate in the blubber. When the orca burns the fat for energy, the PCBs are released into the orca’s system, causing harm. ...
Pharmacodynamics
... effects normally predominate, unless the muscarinic receptors are blocked. (No problem for nerves releasing ACh locally onto nicotinic receptors, however). ...
... effects normally predominate, unless the muscarinic receptors are blocked. (No problem for nerves releasing ACh locally onto nicotinic receptors, however). ...
Toxicodynamics
Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. A biological target, also known as the site of action, can be binding proteins, ion channels, DNA, or a variety of other receptors. When a toxicant enters an organism, it can interact with these receptors and produce structural or functional alterations. The mechanism of action of the toxicant, as determined by a toxicant’s chemical properties, will determine what receptors are targeted and the overall toxic effect at the cellular level and organismal level.Toxicants have been grouped together according to their chemical properties by way of quantitative structure-activity relationships (QSARs), which allows prediction of toxic action based on these properties. endocrine disrupting chemicals (EDCs) and carcinogens are examples of classes of toxicants that can act as QSARs. EDCs mimic or block transcriptional activation normally caused by natural steroid hormones. These types of chemicals can act on androgen receptors, estrogen receptors and thyroid hormone receptors. This mechanism can include such toxicants as dichlorodiphenyltrichloroethane (DDE) and polychlorinated biphenyls (PCBs). Another class of chemicals, carcinogens, are substances that cause cancer and can be classified as genotoxic or nongenotoxic carcinogens. These categories include toxicants such as polycyclic aromatic hydrocarbon (PAHs) and carbon tetrachloride (CCl4). The process of toxicodynamics can be useful for application in environmental risk assessment by implementing toxicokinetic-toxicodynamic (TKTD) models. TKTD models include phenomenas such as time-varying exposure, carry-over toxicity, organism recovery time, effects of mixtures, and extrapolation to untested chemicals and species. Due to their advantages, these types of models may be more applicable for risk assessment than traditional modeling approaches.