Antifungal Agents
... Metabolism is predominantly hepatic, but the propensity for inhibition of mammalian P450 appears to be low. Similar to itraconazole in tits spectrum of action, having good activity against candida species. More effective than itraconazole. ...
... Metabolism is predominantly hepatic, but the propensity for inhibition of mammalian P450 appears to be low. Similar to itraconazole in tits spectrum of action, having good activity against candida species. More effective than itraconazole. ...
Designing Spatially Explicit Agent
... – Reduces food availability, increases disease – Places a control the number of individuals ...
... – Reduces food availability, increases disease – Places a control the number of individuals ...
教案编写基本格式与要求
... chemical reactions without interacting with any receptor. • Receptors are protein molecules present either on the cell surface or with in the cell e.g. adrenergic receptors, cholinoceptors, insulin receptors, etc. • The endogenous neurotransmitters, hormones, autacoids and most of the drugs produce ...
... chemical reactions without interacting with any receptor. • Receptors are protein molecules present either on the cell surface or with in the cell e.g. adrenergic receptors, cholinoceptors, insulin receptors, etc. • The endogenous neurotransmitters, hormones, autacoids and most of the drugs produce ...
Autacoid Drugs Major autacoids
... obstructive pulmonary disease. Salbutamol was the first selective β2-receptor agonist to be marketed — in 1968. The drug was an instant success, and has been used for the treatment of asthma ever since. Salbutamol sulfate is usually given by the inhaled route for direct effect on bronchial smooth mu ...
... obstructive pulmonary disease. Salbutamol was the first selective β2-receptor agonist to be marketed — in 1968. The drug was an instant success, and has been used for the treatment of asthma ever since. Salbutamol sulfate is usually given by the inhaled route for direct effect on bronchial smooth mu ...
Ch.2-1 PPT - Nicholas County Schools
... – Chances for survival of any one species increases by using available resources in different ways – Habitat – an area where an organism lives • Might be a single tree or a whole forest ...
... – Chances for survival of any one species increases by using available resources in different ways – Habitat – an area where an organism lives • Might be a single tree or a whole forest ...
Leukemia incidence of 96000 Hiroshima atomic
... The natural rate of double-strand breaks (DSBs), which is the concern regarding cancer risk, is a thousand times greater than the rate of DSBs by background radiation (Feinendegen et al. 2013). Therefore, low radiation levels are not a significant cause of DNA damage and cancer. How then does ionizi ...
... The natural rate of double-strand breaks (DSBs), which is the concern regarding cancer risk, is a thousand times greater than the rate of DSBs by background radiation (Feinendegen et al. 2013). Therefore, low radiation levels are not a significant cause of DNA damage and cancer. How then does ionizi ...
SEDATIVES / HYPNOTICS Barbiturates • Second choice as sedative
... Ultrashort acting (25 minutes): thiopental Mechanism of Action 1. Facilitation of GABA action on the brain. increase the duration of the GABA gated channel opening but in large dose, they can directly activating chloride channels. (not through BZD receptors). 2. depress excitatory neurotransmitter ...
... Ultrashort acting (25 minutes): thiopental Mechanism of Action 1. Facilitation of GABA action on the brain. increase the duration of the GABA gated channel opening but in large dose, they can directly activating chloride channels. (not through BZD receptors). 2. depress excitatory neurotransmitter ...
Pharma 10
... That is further metabolized into progesterone. Which can be converted to testosterone. ...
... That is further metabolized into progesterone. Which can be converted to testosterone. ...
Convert - public.coe.edu
... Receptor changes shape Excitation or Inhibition? Determined by nature of receptor receptor subtypes NOT NT ~ ...
... Receptor changes shape Excitation or Inhibition? Determined by nature of receptor receptor subtypes NOT NT ~ ...
What Shapes an Ecosystem? Section 4-2
... Predation is an interaction in which one organism captures and feeds on another organism. Symbiosis is any relationship in which two species live closely together. There are 3 main classes of Symbiotic Relationships in nature which are: 1. Mutualism- both species benefit from the relationship. 2. Co ...
... Predation is an interaction in which one organism captures and feeds on another organism. Symbiosis is any relationship in which two species live closely together. There are 3 main classes of Symbiotic Relationships in nature which are: 1. Mutualism- both species benefit from the relationship. 2. Co ...
Executive Summary - BioTech Showcase News
... all three opiate receptors: mu, kappa and delta. These unique ligands have high binding affinity at all three opioid receptors and more balanced receptor activity than other opioids, with partial agonist / antagonist activity at mu, somewhat higher, but not full, kappa agonist activity, and moderate ...
... all three opiate receptors: mu, kappa and delta. These unique ligands have high binding affinity at all three opioid receptors and more balanced receptor activity than other opioids, with partial agonist / antagonist activity at mu, somewhat higher, but not full, kappa agonist activity, and moderate ...
1) Chapter 21 - Ecology Vocabulary
... Abiotic factor – the nonliving parts of an ecosystem including soil, temperature, water, and sunlight Population – a group of the same type of organisms living in the same place at the same time. Community – all the populations that live in an ecosystem. Habitat – place where an organism lives, prov ...
... Abiotic factor – the nonliving parts of an ecosystem including soil, temperature, water, and sunlight Population – a group of the same type of organisms living in the same place at the same time. Community – all the populations that live in an ecosystem. Habitat – place where an organism lives, prov ...
drug_action_notes
... Interfere with the reabsorption and deactivation of transmitter substances (noradrenaline and serotonin) so their effect is enhanced, stimulating the brain. LSD LSD binds to and activates a specific receptor for the neurotransmitter serotonin. Normally, serotonin binds to and activates its receptors ...
... Interfere with the reabsorption and deactivation of transmitter substances (noradrenaline and serotonin) so their effect is enhanced, stimulating the brain. LSD LSD binds to and activates a specific receptor for the neurotransmitter serotonin. Normally, serotonin binds to and activates its receptors ...
chapter 19 Ecology outline
... visible light (it passes through it) *Greenhouse Effect- natural occurring phenomenon that insulates Earth from the deep freeze of space. *Humans have altered the natural greenhouse effect by adding more “green house gases” (CO2) into the atmosphereby burning fossil fuels (coal, oil, natural gas) ...
... visible light (it passes through it) *Greenhouse Effect- natural occurring phenomenon that insulates Earth from the deep freeze of space. *Humans have altered the natural greenhouse effect by adding more “green house gases” (CO2) into the atmosphereby burning fossil fuels (coal, oil, natural gas) ...
9-10 (Pillion) - UAB School of Optometry
... a. The normal, physiological substrate for the estrogen receptors in most females (not a pregnant one) is estradiol. It is called this because it has 2 hydroxyl groups. A –triol has three hydroxyl groups. b. Estradiol is metabolized rapidly to estrone (has double bone O). The activity of the molecul ...
... a. The normal, physiological substrate for the estrogen receptors in most females (not a pregnant one) is estradiol. It is called this because it has 2 hydroxyl groups. A –triol has three hydroxyl groups. b. Estradiol is metabolized rapidly to estrone (has double bone O). The activity of the molecul ...
Biomagnification of PCBs - UNC Institute for the Environment
... • Have students determine the potential health and reproductive effects of PCBs by reviewing published scientific studies that investigated the effect of PCBs on fish, birds, or mammals, including humans. For example, a study by NCSU researchers used a common clam species (Corbicula fluminea) as a m ...
... • Have students determine the potential health and reproductive effects of PCBs by reviewing published scientific studies that investigated the effect of PCBs on fish, birds, or mammals, including humans. For example, a study by NCSU researchers used a common clam species (Corbicula fluminea) as a m ...
Ecosystem Modeling Workshop Co
... Franks and Chen (2000) carried out numerical experiments for 2-D and 3-D cases on Georges Bank: The 2-D experiments were conducted on a south-north transect across the center of GB. The model is driven by tidal forcing only with an assumption that the cross-bank distribution of temperature, phytopla ...
... Franks and Chen (2000) carried out numerical experiments for 2-D and 3-D cases on Georges Bank: The 2-D experiments were conducted on a south-north transect across the center of GB. The model is driven by tidal forcing only with an assumption that the cross-bank distribution of temperature, phytopla ...
Respiratory Drugs
... Fexofenadine (Allegra) ▪Others Cimetidine (Tagament),Rani(Zantac) ,Niza(axid),famo(pepcid) ...
... Fexofenadine (Allegra) ▪Others Cimetidine (Tagament),Rani(Zantac) ,Niza(axid),famo(pepcid) ...
Term Definition Example
... Parent organism splits into Sea Stars and flatworms pieces, each of which can grown into a new organism. ...
... Parent organism splits into Sea Stars and flatworms pieces, each of which can grown into a new organism. ...
Physical-biological Coupling in Marine Ecosystems
... • GLOBEC Goal “…. understand how climate change and variability will translate into changes in the structure and dynamics of marine ecosystems and in fishery production” ...
... • GLOBEC Goal “…. understand how climate change and variability will translate into changes in the structure and dynamics of marine ecosystems and in fishery production” ...
Adverse effects
... endometrium increase during labor and reach peak levels at birth. • Prostaglandins also have a role in preparing the uterus for labor and delivery. ...
... endometrium increase during labor and reach peak levels at birth. • Prostaglandins also have a role in preparing the uterus for labor and delivery. ...
Toxicodynamics
Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. A biological target, also known as the site of action, can be binding proteins, ion channels, DNA, or a variety of other receptors. When a toxicant enters an organism, it can interact with these receptors and produce structural or functional alterations. The mechanism of action of the toxicant, as determined by a toxicant’s chemical properties, will determine what receptors are targeted and the overall toxic effect at the cellular level and organismal level.Toxicants have been grouped together according to their chemical properties by way of quantitative structure-activity relationships (QSARs), which allows prediction of toxic action based on these properties. endocrine disrupting chemicals (EDCs) and carcinogens are examples of classes of toxicants that can act as QSARs. EDCs mimic or block transcriptional activation normally caused by natural steroid hormones. These types of chemicals can act on androgen receptors, estrogen receptors and thyroid hormone receptors. This mechanism can include such toxicants as dichlorodiphenyltrichloroethane (DDE) and polychlorinated biphenyls (PCBs). Another class of chemicals, carcinogens, are substances that cause cancer and can be classified as genotoxic or nongenotoxic carcinogens. These categories include toxicants such as polycyclic aromatic hydrocarbon (PAHs) and carbon tetrachloride (CCl4). The process of toxicodynamics can be useful for application in environmental risk assessment by implementing toxicokinetic-toxicodynamic (TKTD) models. TKTD models include phenomenas such as time-varying exposure, carry-over toxicity, organism recovery time, effects of mixtures, and extrapolation to untested chemicals and species. Due to their advantages, these types of models may be more applicable for risk assessment than traditional modeling approaches.