The Drosophila Sec7 domain guanine nucleotide exchange factor
... Protein trafficking through the secretory pathway plays a key role in epithelial organ development and function. The expansion of tracheal tubes in Drosophila depends on trafficking of coatomer protein complex I (COPI)-coated vesicles between the Golgi complex and the endoplasmic reticulum (ER). How ...
... Protein trafficking through the secretory pathway plays a key role in epithelial organ development and function. The expansion of tracheal tubes in Drosophila depends on trafficking of coatomer protein complex I (COPI)-coated vesicles between the Golgi complex and the endoplasmic reticulum (ER). How ...
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... lobe (Silies et al., 2007; Tayler and Garrity, 2003). In early larval stages the two CG, which are specialized subperineurial glia (SPG), form a tubular glial structure encircled by a monolayer of PG. Photoreceptor axons from the developing ED migrate within this tube in the late third instar to tar ...
... lobe (Silies et al., 2007; Tayler and Garrity, 2003). In early larval stages the two CG, which are specialized subperineurial glia (SPG), form a tubular glial structure encircled by a monolayer of PG. Photoreceptor axons from the developing ED migrate within this tube in the late third instar to tar ...
life cycle, cell wall and cell signal transduction
... A complete understanding of the life cycle of Pneumocystis is difficult because the organism has yet to be grown in continuous ex vivo axenic culture, although growth of Pneumocystis in co-culture with host cells has been described (Schildgen et al. 2014). Pneumocystis has many features to suggest t ...
... A complete understanding of the life cycle of Pneumocystis is difficult because the organism has yet to be grown in continuous ex vivo axenic culture, although growth of Pneumocystis in co-culture with host cells has been described (Schildgen et al. 2014). Pneumocystis has many features to suggest t ...
Three distinct ribosome assemblies modulated by translation are the
... Figure 1. Native human polysomes observed by AFM preserve their in vivo organization and reveal tight ribosome interactions. (a) Typical sedimentation profile of polysomes from MCF-7 cell lysates obtained in a concave 15–50% sucrose gradient. The absorbance peaks corresponding to 40S and ribonucleo ...
... Figure 1. Native human polysomes observed by AFM preserve their in vivo organization and reveal tight ribosome interactions. (a) Typical sedimentation profile of polysomes from MCF-7 cell lysates obtained in a concave 15–50% sucrose gradient. The absorbance peaks corresponding to 40S and ribonucleo ...
Adeno-Associated Virus Vectors for Gene Therapy - diss.fu
... identical for all AAV serotypes. However, most research was performed with AAV2, and it therefore serves as a prototype for the AAV family. Both ends of the AAV genome contain identical inverted terminal repeats (ITRs) of roughly 150 bp [7]. These ITRs form a hairpin-shaped secondary structure throu ...
... identical for all AAV serotypes. However, most research was performed with AAV2, and it therefore serves as a prototype for the AAV family. Both ends of the AAV genome contain identical inverted terminal repeats (ITRs) of roughly 150 bp [7]. These ITRs form a hairpin-shaped secondary structure throu ...
Development of in vitro procedures that can predict the safety of
... Pre-clinical safety testing (in vivo and in vitro) of the therapeutic monoclonal antibody (mAb) TGN1412 (developed for the treatment of autoimmune diseases) failed to predict the life threatening adverse events that occurred during its Phase I Clinical Trial. The treatment of disease using mAb thera ...
... Pre-clinical safety testing (in vivo and in vitro) of the therapeutic monoclonal antibody (mAb) TGN1412 (developed for the treatment of autoimmune diseases) failed to predict the life threatening adverse events that occurred during its Phase I Clinical Trial. The treatment of disease using mAb thera ...
Stacks off tracks
... terminal 463 base pairs, including a transmembrane domain that confers Golgi localisation ...
... terminal 463 base pairs, including a transmembrane domain that confers Golgi localisation ...
Patterson - Iowa State University
... We have focused on the detachment of the petal from the receptacle and have characterized wild type and mutants by analyzing this region. Delayed abscission mutants dab1-1, dab2-1, dab3-1, dab3-2, and dab3-3 display unique anatomical and physiological characteristics. Each mutant is regulated by sin ...
... We have focused on the detachment of the petal from the receptacle and have characterized wild type and mutants by analyzing this region. Delayed abscission mutants dab1-1, dab2-1, dab3-1, dab3-2, and dab3-3 display unique anatomical and physiological characteristics. Each mutant is regulated by sin ...
Fungi
... Athlete’s foot, ringworm, yeast infections, and oral thrush are infections in humans. ...
... Athlete’s foot, ringworm, yeast infections, and oral thrush are infections in humans. ...
Dentin-pulp complex
... With age the pulp becomes less cellular. The number of cells in the dental pulp decreases as cell death occurs with age. The volume of the pulp chamber with continued deposition of dentine. In older teeth, the pulp chamber decreases in size; in some cases the pulp chamber can be obliterated. An ...
... With age the pulp becomes less cellular. The number of cells in the dental pulp decreases as cell death occurs with age. The volume of the pulp chamber with continued deposition of dentine. In older teeth, the pulp chamber decreases in size; in some cases the pulp chamber can be obliterated. An ...
- Wiley Online Library
... Listeria monocytogenes is an ubiquitously occurring Gram-positive rod belonging to the firmicutes. It is present in the soil, on plant surfaces or decaying plant material, where it lives as a saprophyte (Freitag et al., 2009). However, the bacterium is also able to cause infections in humans upon in ...
... Listeria monocytogenes is an ubiquitously occurring Gram-positive rod belonging to the firmicutes. It is present in the soil, on plant surfaces or decaying plant material, where it lives as a saprophyte (Freitag et al., 2009). However, the bacterium is also able to cause infections in humans upon in ...
NCAM Polypeptides in Heart Development: Association with Z Discs
... membrane forms, large cytoplasmic domain (Id) and small cytoplasmic domain (sd), differin the size of their cytoplasmic domains (Hemperly et al., 1986; Murray et al., 1986; He et al., 1986). In addition, small inserts have been identified at two distinctsitesin the extracellularportion of the molecu ...
... membrane forms, large cytoplasmic domain (Id) and small cytoplasmic domain (sd), differin the size of their cytoplasmic domains (Hemperly et al., 1986; Murray et al., 1986; He et al., 1986). In addition, small inserts have been identified at two distinctsitesin the extracellularportion of the molecu ...
Direct Somatic Embryogenesis in Rice (Oryza sativa L - JMS
... medium). Proembryo structure and somatic embryo in early transition stage were found on 5 weeks of culture. Each embryo structure has its own character on cell wall surface. The surface of proembryo cells was smooth (Fig. 5). The smooth surface structure was also shown in proembryo of rice8). Wherea ...
... medium). Proembryo structure and somatic embryo in early transition stage were found on 5 weeks of culture. Each embryo structure has its own character on cell wall surface. The surface of proembryo cells was smooth (Fig. 5). The smooth surface structure was also shown in proembryo of rice8). Wherea ...
Donohoe, B.S., B. - University of Colorado-MCDB
... that the ‘ER-Golgi secretory units’ of the daSilva et al. (26) model correspond to the Golgi stacks that are attached to an active ER export site in the ‘docked’ stage of the ‘dock, pluck and go’ model of Staehelin and Kang (30). These docked Golgi can move around with their attached ER export sites ...
... that the ‘ER-Golgi secretory units’ of the daSilva et al. (26) model correspond to the Golgi stacks that are attached to an active ER export site in the ‘docked’ stage of the ‘dock, pluck and go’ model of Staehelin and Kang (30). These docked Golgi can move around with their attached ER export sites ...
1 - The Mostowy Lab
... Non-canonical autophagy is a new and developing concept, and can be characterized by features that are different from those in canonical autophagy [3]. In particular, non-canonical autophagy is: A mechanism in which the double-membraned autophagosome does not require all of the ATG proteins to for ...
... Non-canonical autophagy is a new and developing concept, and can be characterized by features that are different from those in canonical autophagy [3]. In particular, non-canonical autophagy is: A mechanism in which the double-membraned autophagosome does not require all of the ATG proteins to for ...
Sucrose metabolism: regulatory mechanisms and pivotal roles in
... each site and path of sucrose cleavage described above can initiate a distinctive profile of sugar signals, which in turn can have profound developmental effects (Figure 3). In general, hexoses favor cell division and expansion, whereas sucrose favors differentiation and maturation [6,26,33,34]. Th ...
... each site and path of sucrose cleavage described above can initiate a distinctive profile of sugar signals, which in turn can have profound developmental effects (Figure 3). In general, hexoses favor cell division and expansion, whereas sucrose favors differentiation and maturation [6,26,33,34]. Th ...
Control of Leaf and Vein Development by Auxin
... Figure 2. Stages of leaf development and associated polarities of auxin transport. (A) Leaf initials are specified at the flanks of the SAM ( purple) and correspond to sites of elevated auxin activity (red) resulting from convergence points of PIN1 polarity in the epidermal layer (black arrows). Fro ...
... Figure 2. Stages of leaf development and associated polarities of auxin transport. (A) Leaf initials are specified at the flanks of the SAM ( purple) and correspond to sites of elevated auxin activity (red) resulting from convergence points of PIN1 polarity in the epidermal layer (black arrows). Fro ...
Roles of maltodextrin and glycogen phosphorylases in maltose
... known to be involved in maltose utilization by Gram-positive bacteria. Based on these findings, we conclude that C. glutamicum metabolizes maltose via a pathway involving maltodextrin and glucose formation by MalQ, glucose phosphorylation by Glk and maltodextrin degradation via the reactions of MalP ...
... known to be involved in maltose utilization by Gram-positive bacteria. Based on these findings, we conclude that C. glutamicum metabolizes maltose via a pathway involving maltodextrin and glucose formation by MalQ, glucose phosphorylation by Glk and maltodextrin degradation via the reactions of MalP ...
Biogenesis and multifaceted roles of outer membrane
... proteins called adhesins mediate co-aggregation of bacterial cells and attachment to host surfaces. In Porphyromonas gingivalis, OMVs contain multivalent complexes of adhesins which cause cellular aggregation and the formation of dental plaque biofilms (Grenier & Mayrand, 1987; Inagaki et al., 2006) ...
... proteins called adhesins mediate co-aggregation of bacterial cells and attachment to host surfaces. In Porphyromonas gingivalis, OMVs contain multivalent complexes of adhesins which cause cellular aggregation and the formation of dental plaque biofilms (Grenier & Mayrand, 1987; Inagaki et al., 2006) ...
Host cell interactions of outer membrane vesicle-associated
... endothelial cells (HBMEC), and renal glomerular endothelial cells (HRGEC) in a timedependent manner (Fig 2A, 2D and 2G). There were no significant differences between OMVs from NSF (5791/99) and SF (493/89) EHEC O157 strains, and OMVs containing (5791/99, 493/89) and lacking (493/89Δstx2a) Stx2a (Fi ...
... endothelial cells (HBMEC), and renal glomerular endothelial cells (HRGEC) in a timedependent manner (Fig 2A, 2D and 2G). There were no significant differences between OMVs from NSF (5791/99) and SF (493/89) EHEC O157 strains, and OMVs containing (5791/99, 493/89) and lacking (493/89Δstx2a) Stx2a (Fi ...
Self-Incompatibility-induced Programmed Cell
... Robinson, 1998). There has been much debate about the cytosolic pH gradient, comprising an apical domain ~pH 6.8 and a subapical alkaline band ~pH 7.2 to 7.8 in lily pollen tubes (Fricker et al., 1997; Messerli and Robinson, 1998; Feijo et al., 2001; Lovy-Wheeler et al., 2006). Oscillations of [pH] ...
... Robinson, 1998). There has been much debate about the cytosolic pH gradient, comprising an apical domain ~pH 6.8 and a subapical alkaline band ~pH 7.2 to 7.8 in lily pollen tubes (Fricker et al., 1997; Messerli and Robinson, 1998; Feijo et al., 2001; Lovy-Wheeler et al., 2006). Oscillations of [pH] ...
Alternative splicing of human cyclin E - Journal of Cell Science
... a pRb-induced G1 block (Hinds et al., 1992), as described above for D-type cyclins. The situation is, however, more complex, since later in S-phase cyclin E is found not only in complexes with cdk2, but also with the pRb-related protein p107 and members of the E2F transcription factor family (Lees e ...
... a pRb-induced G1 block (Hinds et al., 1992), as described above for D-type cyclins. The situation is, however, more complex, since later in S-phase cyclin E is found not only in complexes with cdk2, but also with the pRb-related protein p107 and members of the E2F transcription factor family (Lees e ...
as Adobe PDF - Edinburgh Research Explorer
... did not change the pattern of root hair formation or the local increase of XET action. It only resulted in longer root hairs (results not shown). In the auxinresistant (axr2-1) mutant, fewer root hairs were formed than in the wild-type plants, as in the trichoblast cell line not all cells differenti ...
... did not change the pattern of root hair formation or the local increase of XET action. It only resulted in longer root hairs (results not shown). In the auxinresistant (axr2-1) mutant, fewer root hairs were formed than in the wild-type plants, as in the trichoblast cell line not all cells differenti ...
Mitosis
Mitosis is a part of the cell cycle in which chromosomes in a cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus. In general, mitosis (division of the nucleus) is often followed by cytokinesis, which divides the cytoplasm, organelles and cell membrane into two new cells containing roughly equal shares of these cellular components. Mitosis and cytokinesis together define the mitotic (M) phase of an animal cell cycle—the division of the mother cell into two daughter cells, genetically identical to each other and to their parent cell.The process of mitosis is divided into stages corresponding to the completion of one set of activities and the start of the next. These stages are prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the chromosomes, which have already duplicated, condense and attach to fibers that pull one copy of each chromosome to opposite sides of the cell. The result is two genetically identical daughter nuclei. The cell may then divide by cytokinesis to produce two daughter cells. Producing three or more daughter cells instead of normal two is a mitotic error called tripolar mitosis or multipolar mitosis (direct cell triplication / multiplication). Other errors during mitosis can induce apoptosis (programmed cell death) or cause mutations. Certain types of cancer can arise from such mutations.Mitosis occurs only in eukaryotic cells and the process varies in different organisms. For example, animals undergo an ""open"" mitosis, where the nuclear envelope breaks down before the chromosomes separate, while fungi undergo a ""closed"" mitosis, where chromosomes divide within an intact cell nucleus. Furthermore, most animal cells undergo a shape change, known as mitotic cell rounding, to adopt a near spherical morphology at the start of mitosis. Prokaryotic cells, which lack a nucleus, divide by a different process called binary fission.