• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Concepts of Pharmacology - Half Life Calculation
Concepts of Pharmacology - Half Life Calculation

... represent the time required for a drug to reach half of its initial concentration after administration • This is because in a single-compartment model elimination is the only process that can alter drug concentration • Intercompartmental distribution cannot occur because there are no other compartme ...
Concepts of Pharmacology - Half Life Calculation -
Concepts of Pharmacology - Half Life Calculation -

... represent the time required for a drug to reach half of its initial concentration after administration • This is because in a single-compartment model elimination is the only process that can alter drug concentration • Intercompartmental distribution cannot occur because there are no other compartme ...
Uses and abuses of genetic engineering
Uses and abuses of genetic engineering

... in the drosophila genome using interfering RNA technology it is possible to work out which gene products control the cell cycle. Since around 40% of human genes are identifiable in the drosophila genome and genes that control the cell cycle are highly conserved in evolution, this approach is expecte ...
7.1 Chromosomes and Phenotype
7.1 Chromosomes and Phenotype

... – How are Mendel’s observations related to genes on autosomes? – Why are males more likely than females to have sex-linked genetic disorders? – How are autosomal traits, including recessive genetic disorders that are carried in a population, related to Mendel’s observations of heredity? – Describe h ...
Old GUT Anorexia and Constipation
Old GUT Anorexia and Constipation

... and malabsorption of multiple nutrients in small intestine add to the digestive issues. Decreased tone of abdominal muscles may affect peristalsis and evacuation may not be complete. There is reduction in the liver mass and hepatic blood flow compromising the ability to metabolize and detoxify toxin ...
Metabolizing Enzymes and Transporter Proteins: How
Metabolizing Enzymes and Transporter Proteins: How

... drug interactions is the CYP group. Enzyme inhibition leads to decreased drug metabolism, which in turn, increases the drug levels in the body. Identifying the type of inhibition may help counter it during clinical drug administration. On the other hand, a more complex phenomenon that can lead to dr ...
Schedule
Schedule

... relative to each other. OR Because recombination is random, its effect on the level of variation is different in each case, but has the potential to add significant changes to the already high degree of variability caused by independent assortment. In segregation the copies of a gene separate, so th ...
Anticoagulants and Applicable Disease States for Pharmacy
Anticoagulants and Applicable Disease States for Pharmacy

... objectivity in all its individually or jointly presented continuing pharmacy education programs. All faculty participating in any ICHP continuing pharmacy education programs are expected to disclose any real or apparent conflict(s) of interest that may have any bearing on the subject matter of the c ...
78KB - NZQA
78KB - NZQA

... relative to each other. OR Because recombination is random, its effect on the level of variation is different in each case, but has the potential to add significant changes to the already high degree of variability caused by independent assortment. In segregation the copies of a gene separate, so th ...
Uses
Uses

... enhance the immune response •sports performance - mixed results but generally negative •mental functioning – mixed results but some intriguing results indicate promise for enhancing completion of mental tasks and (in combination with ginkgo) memory and a recent study gave suggestive evidence of impr ...
Inpatient Warfarin Counseling
Inpatient Warfarin Counseling

... formation of clots in your blood  Why was warfarin prescribed for you?  Sometimes medical conditions can make blood clot too easily and quickly  This could cause serious health problems because clots can block the flow of blood to the heart or brain  Warfarin can prevent harmful clots from ...
Clinical Exome Sequencing at GeneDx Cheryl Scacheri, MS, LGC Licensed Genetic Counselor
Clinical Exome Sequencing at GeneDx Cheryl Scacheri, MS, LGC Licensed Genetic Counselor

... Pseudogenes and homologous regions may also be captured. This may reduces the sensitivity Sequencing multiple family members can compensate for low coverage when a variant is observed in multiple family members (Trios are usually best: proband and both parents). ...
Basic Nursing: Foundations of Skills and Concepts Chapter 24
Basic Nursing: Foundations of Skills and Concepts Chapter 24

... administration of medications that is set up by the hospital nursing service • You are required to learn the hours that are standard for your hospital • Note: Standard prn orders are never assigned a time, because the drugs are administered as they are needed by the patient ...
2355 Switching from a low dose Intravenous iron prepartion to a
2355 Switching from a low dose Intravenous iron prepartion to a

... administered into a vein. New guidance recommending resuscitation equipment is available for all IV iron administration means most IV iron is being given in a hospital setting (MHRA). For patients not receiving haemodialysis, (HD) this means attending an outpatient department at the hospital. Hospit ...
rajiv gandhi university of health sciences, karnataka
rajiv gandhi university of health sciences, karnataka

... have confirmed that microsponge systems are non-irritating, non-mutagenic, non-allergenic, and non-toxic. MDS technology is being used currently in cosmetics, over-the-counter (OTC) skin care, sunscreens and prescription products.6 Microsponges have the ability to entrap wide range of active materia ...
File
File

... • Product confusion – marketing strategies • Therapeutic duplication • Therapeutic failure • Poor self care choices • Incorrect dosing • Drug interactions • Uncertainty regarding duration of therapy • Patients assumptions that OTC medications are not “real drugs” Conditions commonly treated with sel ...
Toward drugs derived from cannabis
Toward drugs derived from cannabis

... ca. 5 mg, the side effects (euphoria and postural hypotension) were significant though tachycardia was not observed. On chronic treatment (1 or 2 mg twice daily) tolerance developed to the side effects, while the sedative-relaxant effect was apparently still significant. This last point needs furthe ...
Chapter 5 - Genetics, Sections 1, 2, 3 STUDY GUIDE
Chapter 5 - Genetics, Sections 1, 2, 3 STUDY GUIDE

... EXAMPLE: Genes affect a person’s chances of having heart disease. However, what a person eats and the amount of exercise he or she gets can influence whether heart disease will develop. ...
Antidepressant Presentation
Antidepressant Presentation

... release of steroids are being developed as AD ...
藥物投予方式
藥物投予方式

... – ACh is the neurotransmitter at airway smooth muscle – it acts at M3 receptors- activation causes formation of IP3 (increasing Ca2+) and diacylglycerol F tension is the result ...
Document
Document

... Dosage that depends on surface area… The dosage of some drugs is calculated based on the body surface area of the recipient. Surface area is measured in meters squared (m2). When the total body surface area is known, the correct drug dosage can be determined. Let’s consider a problem: The patient i ...
Drug concentration in lung tissue in multidrug-resistant tuberculosis
Drug concentration in lung tissue in multidrug-resistant tuberculosis

... for MDR-TB is solely based on sputum smear and culture status [1]. Studies with individualised treatment that studied treatment success have predominantly been based on DST results [7], without using pharmacokinetics with TDM. Although TDM may help evaluate TB drug absorption, even this aspect has n ...
SIMPLE PATTERNS OF INHERITANCE
SIMPLE PATTERNS OF INHERITANCE

... diseases in which a recessive allele fails to produce a specific active protein  Over 7,000 human disorders caused by mutations in a single gene  Majority are recessive but some are dominant  Pleiotropy- mutation in a single gene has ...
Sheet_18
Sheet_18

...  As a definitive therapy, doxycycline can be used for treatment of atypical pneumonia. (after the culture results are back telling you that the cause of atypical pneumonia in your patient is mycoplasma for example). Mycoplasma pneumoniae is a common cause of peumonia in young adults and in people w ...
product information - Secure Data Warehouse
product information - Secure Data Warehouse

... arrhythmia, congestive heart failure, *cardiomyopathy). (See also PHARMACOLOGY, Non-clinical QT Interval Data). Drug Interactions Concomitant medication with other drugs that possess anticholinergic properties may result in more pronounced therapeutic effect and side-effects. Conversely, the therape ...
< 1 ... 887 888 889 890 891 892 893 894 895 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report