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Top 20 Prescribed Drugs 2013
Top 20 Prescribed Drugs 2013

... MOA: likely due to PDE-5 mediated reduction in smooth muscle and endothelial cell proliferation, decreased nerve activity, and increased smooth muscle relaxation. PAH: pulmonary vasculature relaxation. ...
Review and Non-Mendelian Genetics
Review and Non-Mendelian Genetics

... and the other has green pods. Yellow is dominant to green. Parent plant genotypes ____ X ____ Draw Punnett square. What phenotypic results will the student find in the F1 generation? ...
ISMP Medication Safety Alert
ISMP Medication Safety Alert

... Oneof themost important ways toprevent medication errors is tolearn about problems that haveoccurred in other organizations and tousethat information toprevent similar problems at your practicesite. To promotesuch aprocess, thefollowing selected items fromthe July-September 2012 issues of theISMPMed ...
File
File

... European descent but is much rarer in other groups. One out of 25 whites (4% ) is a carrier. The normal allele for this gene codes for a membrane protein that functions in chloride ion transport between certain cells and the extracellular fluid. These chloride channels are defective or absent. The r ...
Inhalant Abuse: A Curse to the New Generation
Inhalant Abuse: A Curse to the New Generation

... doses, an addicted teens’ limbic system crave for the A doctor should be consulted if a child or adolescent drug as it craves for food. Because of the down is found to be abusing inhalants. A young teenager who regulation drug craving is made worse. Without the is in the habit of glue sniffing needs ...
Facts about long-term medications
Facts about long-term medications

... We’ll test total levels of T4 (a thyroid hormone) one month after beginning levothyroxine, then every six months to ensure proper dosing. Occasionally another test—free T4 by equilibrium dialysis—will be necessary. We’ll need to take blood tests four to six hours after administration. At proper leve ...
baclofen
baclofen

APHardyWeinberg
APHardyWeinberg

... Six Fingers is dominant…why do most of us have 5? Why do many Northern Europeans carry the lethal recessive CF allele? ...
Our Experience - Contemporary Care
Our Experience - Contemporary Care

... from a 24 to a 0 and her AH completely disappeared. Due to this result, and a re-analysis of the patient's symptoms, the patient was re-diagnosed with Severe Depression with psychotic features. She continues to be in remission to date, five months after she has completed TMS. ...
Automated discovery of drug treatment patterns for endocrine
Automated discovery of drug treatment patterns for endocrine

... the secondary uses of the EMR by creating operational EMR mirrors for research purposes as exemplified by the Mayo Clinic Enterprise Data Trust (EDT)8 and Informatics for Integrating Biology and the Bedside (i2b2) datamarts.9 In an August, 2011 JAMA editorial, Jha10 discusses the promises of the EMR, ...
Inhaler Technology—Improving Prevention and Reversal of
Inhaler Technology—Improving Prevention and Reversal of

... scheduled, daily, long-term use.5 It is not within the scope of this article to provide an in-depth review of the current clinical evidence for SABAs in the treatment of acute symptoms, but a number of extensive reviews and guidelines have been published.5–11 In general, the selective SABAs albutero ...
File
File

... SHOOTING GALLERY: Is the place where heroin activities are ...
lfs in class
lfs in class

... You are worried about sharing your suspicions with Lee and Grace, but for different reasons. Grace, who is still recovering from breast cancer surgery and chemotherapy, seems very fragile as well as distraught that her son has a tumor-like growth. If Lee did, in fact, inherit a faulty gene from her ...
Preparing for safety issues following drug approval: pre
Preparing for safety issues following drug approval: pre

10/01 02/03 This policy is applicable to the following Henry Ford Health...
10/01 02/03 This policy is applicable to the following Henry Ford Health...

... The Ambulatory and Inpatient Pharmacy and Therapeutics Committees discourage the use of sample medications except for selected clinics/providers who comply with the legal and regulatory issues governing the labeling, stocking, dispensing, and recording of sample medications as outlined in the proced ...
Throughout document
Throughout document

... 3.15.2 Medication error reported without clinical consequences The section header was reworded to “Medication errors and potential medication errors reported without clinical consequences”. A third paragraph was added to this section as follows: In instances where the medication did not reach the pa ...
Hypertension update
Hypertension update

... Bone marrow depression up to 10% in renal failure patients on captopril (sulfhydryl gp.) especially autoimmune disease, therefore close monitor of WBC, and low dose captopril. Central alpha-2 agonists as clonidine appear to be the safest in the dialysis population. Trans dermal clonidine up to 1.2mg ...
Study Results Published in Journal of Clinical Infectious Diseases
Study Results Published in Journal of Clinical Infectious Diseases

... - First Head-to-Head, Blinded Safety Comparison of Lipid-Based Amphotericin B Agents Deerfield, IL and Foster City, CA -- November 17, 2000 Fujisawa Healthcare, Inc. (FHI) and Gilead Sciences, Inc. (Nasdaq: GILD) today announced the publication of results of a multicenter head-to-head study comparin ...
Drug-Induced Hepatotoxicity
Drug-Induced Hepatotoxicity

... reticulum of the liver.  It is found also in other sites: Gastrointestinal tract. Brain. Kidneys. Other tissues. ...
Prescription Drug Abuse
Prescription Drug Abuse

... who abuse opioids may seek to intensify their experience by taking the drug in ways other than those prescribed. For example, OxyContin is an oral medication used to treat moderate to severe pain through a slow, steady release of the opioid. People who abuse OxyContin may snort or inject it,2 thereb ...
Appetite Suppressants
Appetite Suppressants

... The preceding policy applies only to members for whom the above named pharmacy benefit medications are included on their covered formulary. Members with closed formulary benefits are subject to trying all appropriate formulary alternatives before a coverage exception for a non-formulary agent will b ...
AP Biology – PowerPoint Notes – Chapter 11 & 12 ‐ Patterns of Heredity and Human Genetics 
AP Biology – PowerPoint Notes – Chapter 11 & 12 ‐ Patterns of Heredity and Human Genetics 

... If type B blood is put into their bodies, their immune system reacts as if it were  a foreign invader, the antibodies clump the blood ‐ can cause death.   ...
PowerPoint 演示文稿
PowerPoint 演示文稿

...  (2) symptomatic treatment  (3) supplement therapy ...
Genetic Punnett Squares PPT
Genetic Punnett Squares PPT

... TRAIT COVERED UP BY DOMINATE TRAIT Only seen if 2 recessive genes present. ...
glucagon - DavisPlus
glucagon - DavisPlus

... Assess for nausea and vomiting after administration of dose. Protect patients with depressed level of consciousness from aspiration by positioning on side; ensure that a suction unit is available. Notify health care professional if vomiting occurs; patient will require parenteral glucose to prevent ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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