• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
sheet_4
sheet_4

... histolytica. (hepatic abscess; intestinal wall/ extraintestinal infections) • Not effective against luminal parasites and so must be used with a luminal amebicide to ensure eradication of the infection. kills trophozoites but not cysts ...
Current Drug Trends
Current Drug Trends

... as 12% alcohol in 24 oz. single-serving containers, alcopops are the equivalent of 3-5 beers. Many state attorney generals call them a "binge in a can." ...
file
file

... Cross – pollination ...
Key Learning Guide - City Vision University
Key Learning Guide - City Vision University

... Schedule IV drugs have a low potential for abuse, have a currently accepted medical use, has a low chance for addiction or limited addictive properties. Examples of Schedule IV drugs include Valium, Xanax, Phenobarbital, and Rohypnol (commonly known as the "date rape" drug). These drugs may be avail ...
Lectures 15-17: Patterns of Inheritance Genotype Vs. Phenotype
Lectures 15-17: Patterns of Inheritance Genotype Vs. Phenotype

... a. Everyone is slightly different due to their genetic code, due to unrepaired mutations in (usually) non-coding regions b. Humans are 99.9% identical c. Human genome project identified 1.45 million known SNPs (single nucleotide polymorphisms) and the differences were evaluated for its association w ...
Anti-TB - PharmaStreet
Anti-TB - PharmaStreet

... •Rifampin is a microsomal enzyme inducer-increases severalCYP3A4, CYP2D6,CYP1A2 and CYP2C subfamily. •It thus enhances its own metabolism as well as that of many drugs including warfarin, oral contraceptives, corticosteroids, sulfonyl ureas, steroids, HIV protease inhibitors, non nucleoside reverse ...
SSTOP drugs Word file
SSTOP drugs Word file

... Appendix 1: STOPP (Screening Tool of Older People’s potentially inappropriate Prescriptions). The following prescriptions are potentially inappropriate in persons aged  65 years of age A. ...
Maropitant: Novel Antiemetic
Maropitant: Novel Antiemetic

... Substance P has also been implicated in bladder hyperalgesia and airway hyperreactivity. In fact, NK-1 receptor antagonists have demonstrated efficacy in human patients with overactive bladders20 and in animal models of allergic bronchial disease21 and induced cough.22 Additional studies are needed ...
Heritability of type 2 diabetes
Heritability of type 2 diabetes

...  These results may be due to higher influence of environmental factors in 60-75 age groups  On the other hand lower h2 in individuals younger than 40 years, may be due to incomplete penetrance ...
7.1 Chromosomes and Phenotype
7.1 Chromosomes and Phenotype

... – X chromosome inactivation randomly “turns off” one X chromosome. ...
Genetics
Genetics

... environments. Greater variation within the species makes a population better suited to adaptation to changes in the environment. ...
MIC
MIC

... III. Future Directions: What role do birds play in the transmission of drug-resistant bacteria? ...
Arterial Hypertension
Arterial Hypertension

... such as reduced ability to protect against stroke and adverse effects on lipid metabolism and new onset diabetes (contraindication with multiple metabolic risk factors). 2) Diuretics (mostly thiazide) are still a well accepted treatment. Loop diuretics are not generally a first-line treatment as the ...
NICE TA 315. Shared Care available
NICE TA 315. Shared Care available

... empagliflozin has evidence to show positive cardiovascular outcomes. This may be a class effect of the drugs, however, it seems reasonable to suggest that empagliflozin should be used in preference to other SGLT2 inhibitors until further research is published. See trial summary below: Empagliflozin ...
PHENDIMETRAZINE TARTRATE TABLETS, USP 35 Mg
PHENDIMETRAZINE TARTRATE TABLETS, USP 35 Mg

... Phendimetrazine tartrate should not be used in combination with other anorectic agents, including prescribed drugs, over-the-counter preparations and herbal products. In a case-control epidemiological study, the use of anorectic agents, including phendimetrazine tartrate, was associated with an incr ...
Testing_Issues_ASHG - Berkshire Health Systems
Testing_Issues_ASHG - Berkshire Health Systems

... negative test result on medical management? Personal decision-making? Risks to other family members? • Who is going to help explain the results to all the family ...
$doc.title

... File No. 152106-001-SF ...
recent trends in pharmaceutical chemistry for drug discovery
recent trends in pharmaceutical chemistry for drug discovery

... system. For example, if the desired effect of a drug is to inhibit a particular enzyme, the enzyme can be isolated from an organ and studied in a test tube. New technologies have made it possible to assay large numbers of compounds in a short period. High-throughput drug screening allows pharmaceuti ...
Restless legs syndrome
Restless legs syndrome

... The Red Whale | GP Update Course – The one day course for GPs and GP Registrars, by GPs. (We think it’s the most fun you can have earning CPD credits!) The GP Update Course brings you up to speed with all the latest issues, guidelines and research. Run entirely by GPs, we trawl through all the lite ...
ISMP Medication Safety Alert - Institute For Safe Medication Practices
ISMP Medication Safety Alert - Institute For Safe Medication Practices

... two 10 mL vials) may serve ISMP MedicationSafetyAlert! ...
L11- ANTIPLATELET DRUGS
L11- ANTIPLATELET DRUGS

... Platelets and vessels • In healthy vasculature, nitric oxide and prostacyclin (released by endothelial cells lining the blood vessels) inhibit platelets aggregation. • An injury to vascular system leads to interaction between Platelets, Endothelial system and Coagulation factors which lead to forma ...
Why Generics companies?
Why Generics companies?

... • Partnership with Glaxo holdings plc to develop genetic code-blockers for cancer’s treatment ($8 million). • Dr John Martin a specialist in nucleic acid chemistry was recruited by Gilead “came from BMS” ...
Genetics Basics POGIL
Genetics Basics POGIL

... Which letters are used to represent the gene for body color? _________________________________________ Which letters are used to represent the gene for neck length? ________________________________________ Which letters are used to represent the gene for fire breathing ability? _____________________ ...
Botanix Secures Commercial-Scale Synthetic
Botanix Secures Commercial-Scale Synthetic

... (“Botanix” or “the Company”) today announced that it has secured a supply of synthetic cannabidiol, which has been manufactured at commercial scale by its US-based partner. Unlike cannabidiol sourced from natural extracts, pharmaceutical grade synthetic cannabidiol (referred to chemically as 2-[(1R, ...
Linked genes
Linked genes

... INHERITANCE • Morgan classified the offspring from the testcross matings according to phenotype • He found a much higher proportion of parental phenotypes than would be expected if the genes assorted independently. • Body color and wing size must usually be inherited together, and therefore be locat ...
< 1 ... 880 881 882 883 884 885 886 887 888 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report