Guidelines on the quality, safety, and efficacy of biotherapeutic
... requirements for, and the type of, studies is recommended. Some aspects of manufacturing and quality control in these guidelines may apply to protein-based vaccine antigens made by rDNA technology. However, more detailed guidelines/recommendations on vaccine evaluation in terms of quality, safety an ...
... requirements for, and the type of, studies is recommended. Some aspects of manufacturing and quality control in these guidelines may apply to protein-based vaccine antigens made by rDNA technology. However, more detailed guidelines/recommendations on vaccine evaluation in terms of quality, safety an ...
Implications of Recent Clinical Trials for the National Cholesterol
... ranges from 160 to 189 mg/dL, introduction of a cholesterol-lowering drug is a therapeutic option in appropriate circumstances, such as when a severe risk factor is present. ATP III outlines several factors that can be taken into consideration to guide clinical judgment for this category. ATP III pl ...
... ranges from 160 to 189 mg/dL, introduction of a cholesterol-lowering drug is a therapeutic option in appropriate circumstances, such as when a severe risk factor is present. ATP III outlines several factors that can be taken into consideration to guide clinical judgment for this category. ATP III pl ...
The following table lists plants and herbal remedies proven or
... 127 articles published in the previous 2 years. Many of these articles document small, uncontrolled, exploratory studies on the effectiveness of particular substances for disorders for which they have been traditionally prescribed. In a recent comprehensive review of the scientific literature, many ...
... 127 articles published in the previous 2 years. Many of these articles document small, uncontrolled, exploratory studies on the effectiveness of particular substances for disorders for which they have been traditionally prescribed. In a recent comprehensive review of the scientific literature, many ...
product information
... (baseline LDL-C range 3.4 to 4.9 mmol/L). In this double blind, multicentre, controlled clinical trial in which 408 patients were randomised, angiograms were evaluated at baseline and at three years in 264 patients. No statistically significant difference between pravastatin and placebo was seen for ...
... (baseline LDL-C range 3.4 to 4.9 mmol/L). In this double blind, multicentre, controlled clinical trial in which 408 patients were randomised, angiograms were evaluated at baseline and at three years in 264 patients. No statistically significant difference between pravastatin and placebo was seen for ...
Product Monograph
... Carcinogenesis, Mutagenesis, Impairment of Fertility There are no animal or laboratory studies on the combination product (tramadol and acetaminophen) to evaluate carcinogenesis, mutagenesis, or impairment of fertility. A slight but statistically significant increase in two common murine tumours, pu ...
... Carcinogenesis, Mutagenesis, Impairment of Fertility There are no animal or laboratory studies on the combination product (tramadol and acetaminophen) to evaluate carcinogenesis, mutagenesis, or impairment of fertility. A slight but statistically significant increase in two common murine tumours, pu ...
Fentanyl Buccal Lozenges (Actiq®)
... All patients receiving fentanyl sublingual tablets, including those patients previously treated with other fentanyl dosage forms, should initially receive a 100 mcg dose. If patients do not achieve adequate analgesia within 30 minutes, a second fentanyl sublingual tablet dose may be administered as ...
... All patients receiving fentanyl sublingual tablets, including those patients previously treated with other fentanyl dosage forms, should initially receive a 100 mcg dose. If patients do not achieve adequate analgesia within 30 minutes, a second fentanyl sublingual tablet dose may be administered as ...
VariantFiltering: filtering of coding and non-coding
... Here the Level column refers to the shortest-path distance to the most general SO term sequence_variant within the SO ayclic digraph. We can use this level value to interrogate the annotations on a specific granularity: ...
... Here the Level column refers to the shortest-path distance to the most general SO term sequence_variant within the SO ayclic digraph. We can use this level value to interrogate the annotations on a specific granularity: ...
The Frequency Distribution of Nucleotide Variation in Drosophila
... 0.11). This dependence of the statistical results on period data could be indicative of locus effects or could be attributable to reduced power associated with removal of a large amount of data from the analysis. The conclusion of roughly equal numbers of preferred and unpreferred fixations is based ...
... 0.11). This dependence of the statistical results on period data could be indicative of locus effects or could be attributable to reduced power associated with removal of a large amount of data from the analysis. The conclusion of roughly equal numbers of preferred and unpreferred fixations is based ...
1 Atrial fibrillation
... education programs should be developed. In addition a campaign aimed at improving the awareness of AF should be developed for both health professionals and consumers. The most common antithrombotic medicines that are used for the reduction of stroke risk at the present time are the anticoagulant war ...
... education programs should be developed. In addition a campaign aimed at improving the awareness of AF should be developed for both health professionals and consumers. The most common antithrombotic medicines that are used for the reduction of stroke risk at the present time are the anticoagulant war ...
Only for the use of Medical Professionals
... Dilup 20/50: 1 to 4 tablets daily according to patient’s response Dilup 40/50: 1 to 2 tablets daily for patient’s previously stabilized with higher doses of Spironolactone and Furosemide Use in pregnancy and lactation There is a clinical evidence of safety of Furosemide in pregnancy but Spironolacto ...
... Dilup 20/50: 1 to 4 tablets daily according to patient’s response Dilup 40/50: 1 to 2 tablets daily for patient’s previously stabilized with higher doses of Spironolactone and Furosemide Use in pregnancy and lactation There is a clinical evidence of safety of Furosemide in pregnancy but Spironolacto ...
Pralidoxime Iodide Injection
... Intravenous administration of Pralidoxime Iodide Injection should be carried out slowly and, preferably, by infusion, since certain side effects, such as tachycardia, laryngospasm, and muscle rigidity, have been attributed in a few cases to a too rapid rate of injection (see Dosage and Administratio ...
... Intravenous administration of Pralidoxime Iodide Injection should be carried out slowly and, preferably, by infusion, since certain side effects, such as tachycardia, laryngospasm, and muscle rigidity, have been attributed in a few cases to a too rapid rate of injection (see Dosage and Administratio ...
Reconsidering GHB: orphan drug or new model antidepressant?
... monoamine re-uptake from the synaptic cleft. Tricyclic antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and the new generation of dual antidepressants all exert their antidepressant effects by this mechanism. In the early days of the monoaminergic era, other efforts have been made t ...
... monoamine re-uptake from the synaptic cleft. Tricyclic antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and the new generation of dual antidepressants all exert their antidepressant effects by this mechanism. In the early days of the monoaminergic era, other efforts have been made t ...
garter snake - University of Notre Dame
... genotypes (Nav1.4 and microsatellites) in a local sample of Thamnophis atratus and Thamnophis sirtalis. Allelic variation in Nav1.4 explains 23 per cent of the variation in TTX resistance in T. atratus while variation in a haphazard sample of the genome (neutral microsatellite markers) shows no asso ...
... genotypes (Nav1.4 and microsatellites) in a local sample of Thamnophis atratus and Thamnophis sirtalis. Allelic variation in Nav1.4 explains 23 per cent of the variation in TTX resistance in T. atratus while variation in a haphazard sample of the genome (neutral microsatellite markers) shows no asso ...
Abstracts - Parthenon Management Group
... each making a small contribution to risk of the disorder, and it also clear from multi-locus tests that perhaps a thousand or more such risk variants exist. There is also substantially evidence that these common variants overlap with those that confer risk for bipolar disorder, and emerging evidence ...
... each making a small contribution to risk of the disorder, and it also clear from multi-locus tests that perhaps a thousand or more such risk variants exist. There is also substantially evidence that these common variants overlap with those that confer risk for bipolar disorder, and emerging evidence ...
12 Fluconazole – A Review of Its Use in Children
... fluconazole should be cautioned not to rely on oral contraceptives as their sole means of birth control.2 Adverse Effects In pre-marketing clinical trials, the most frequent adverse effects associated with fluconazole were nausea (in 3.7% of patients), headache (1.9%), skin rash (1.8%), vomiting (1. ...
... fluconazole should be cautioned not to rely on oral contraceptives as their sole means of birth control.2 Adverse Effects In pre-marketing clinical trials, the most frequent adverse effects associated with fluconazole were nausea (in 3.7% of patients), headache (1.9%), skin rash (1.8%), vomiting (1. ...
Effects of oral phentolamine, taken before sleep, on nocturnal
... Male Aging Study (MMAS), has recognized several target groups, who are at risk for ED.1 At the ages between 40 and 49 y the incidence rate of ED is 12.4=1000 men, increasing with each decade of age and reaching 45.8=1000 for males aged between 60 and 69 y. Moreover, men with hypertension, diabetes, ...
... Male Aging Study (MMAS), has recognized several target groups, who are at risk for ED.1 At the ages between 40 and 49 y the incidence rate of ED is 12.4=1000 men, increasing with each decade of age and reaching 45.8=1000 for males aged between 60 and 69 y. Moreover, men with hypertension, diabetes, ...
Carisoprodol: an underrecognized drug of abuse in north India
... carisoprodol intake (4.5 vs. 3.5 years), and a longer period of carisoprodol intake (61 vs. 33 months). Also in comparison to our previous study [12] the most common initiator to carisoprodol intake was co-addicts (vs. local chemist), and the most common reason for initiating carisoprodol was for be ...
... carisoprodol intake (4.5 vs. 3.5 years), and a longer period of carisoprodol intake (61 vs. 33 months). Also in comparison to our previous study [12] the most common initiator to carisoprodol intake was co-addicts (vs. local chemist), and the most common reason for initiating carisoprodol was for be ...
LSEHWP39
... their combinations are set out in Table 1. Databases were searched using the primary term “epilepsy” in combination with pregnancy or pregnant (column 2 in Table 1) and one term associated with drug treatment (column 3 of Table 1). ...
... their combinations are set out in Table 1. Databases were searched using the primary term “epilepsy” in combination with pregnancy or pregnant (column 2 in Table 1) and one term associated with drug treatment (column 3 of Table 1). ...
Inhibition of N-Nitrosodimethylamine Metabolism
... ance was not significantly affected by exposing animals to ether for 5-10 min before drug administration, but that continuous ether anesthesia reduced the clearance by roughly 4-fold. In addition continuous ether treatment resulted in a 2.5-fold depres sion of aminopyrine clearance (9) relative to u ...
... ance was not significantly affected by exposing animals to ether for 5-10 min before drug administration, but that continuous ether anesthesia reduced the clearance by roughly 4-fold. In addition continuous ether treatment resulted in a 2.5-fold depres sion of aminopyrine clearance (9) relative to u ...
Serotonin Syndrome
... The reported drug interactions that have caused serotonin syndrome continue to increase and include many different combinations of serotonergic drugs. Some of the reported drug combinations are listed in Table 4. The most well-known combination is an SSRI with an MAOI. However, the combination of an ...
... The reported drug interactions that have caused serotonin syndrome continue to increase and include many different combinations of serotonergic drugs. Some of the reported drug combinations are listed in Table 4. The most well-known combination is an SSRI with an MAOI. However, the combination of an ...
From RNA to protein
... Genes to Phenotypes "A set of genes represents the individual components of the biological system under scrutiny" Modifications of the "3:1 F2 monohybrid ratio" and gene interactions are the rules rather than the exceptions" ...
... Genes to Phenotypes "A set of genes represents the individual components of the biological system under scrutiny" Modifications of the "3:1 F2 monohybrid ratio" and gene interactions are the rules rather than the exceptions" ...
Panadol® Osteo - GSK Australia
... favour of PANADOL Osteo were observed at the later time points. Furthermore, PANADOL Osteo was significantly more effective than standard immediate release paracetamol for the summed pain intensity difference at 6 hours (p = 0.0344) and 8 hours (p = 0.0500), as measured on a visual analogue scale. F ...
... favour of PANADOL Osteo were observed at the later time points. Furthermore, PANADOL Osteo was significantly more effective than standard immediate release paracetamol for the summed pain intensity difference at 6 hours (p = 0.0344) and 8 hours (p = 0.0500), as measured on a visual analogue scale. F ...
SEDATIVE-HYPNOTICS: Barbiturates (p.1) History these drugs were
... SEDATIVE-HYPNOTICS: Barbiturates (p.1) History these drugs were the major tx option for anxiety & insomnia from 1912 to 1960 they were very likely to be abused often used in suicide and attempted suicide caused accidental deaths in Ss who took them w/ ETOH or in combination with other S-Hs 1.Pharmac ...
... SEDATIVE-HYPNOTICS: Barbiturates (p.1) History these drugs were the major tx option for anxiety & insomnia from 1912 to 1960 they were very likely to be abused often used in suicide and attempted suicide caused accidental deaths in Ss who took them w/ ETOH or in combination with other S-Hs 1.Pharmac ...
PGY1 - ASHP Media
... Programs. Users of this document will want to refer to the accompanying glossary to assure a shared understanding of terms. The order in which the required educational outcomes is presented in this document does not suggest relative importance of the outcome, amount of time that should be devoted to ...
... Programs. Users of this document will want to refer to the accompanying glossary to assure a shared understanding of terms. The order in which the required educational outcomes is presented in this document does not suggest relative importance of the outcome, amount of time that should be devoted to ...