• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Cholesterol Medication Fact Sheets
Cholesterol Medication Fact Sheets

... This results in lowering triglyceride and LDL cholesterol levels. It also raises HDL cholesterol. Generally LDL cholesterol is reduced by 15-30%, triglyceride is reduced by 40%, and HDL is increased by 20%. Nicotinic acid has also been shown to slow progression or reverse the process of atherosclero ...
Serotonin Syndrome Caused by Moclobemide
Serotonin Syndrome Caused by Moclobemide

... response can be observed. Both drugs are metabolised by CYP2C19 enzyme. The other enzymes CYP1A2 and CYP2D6 responsible for clomipramine metabolism are inhibited by moclobemide (19). Moclobemide has been shown to have similar antidepressant efficacy to tricyclic antidepressants, selective serotonin ...
Genetics PowerPoint
Genetics PowerPoint

... These two alleles are inherited, one parent If the offspring from each _______. receives a dominant allele from one parent, that dominant trait will ...
Migraine drug table
Migraine drug table

... Children: 10-15 mg/kg Adults: 400 mg q 4-6 hrs 5 mg/kg (275-375 mg)/dose given BID Adults: start at 80 mg/day ÷ BID, advance slowly to effective dose (usually 160-240 mg/day ÷ TID) Children: start at 1 mg/kg/day ÷ TID, advance to 2-4 mg/kg/day ÷ TID ...
assessment and management of pain in hemophilia patients
assessment and management of pain in hemophilia patients

... adversely affected by pain specific to synovitis and joint arthropathy. Pain assessment is an essential component of adequate care, and some examples that are more applicable to the haemophilia patient are included (Table 2) [15–19]. ...
Document
Document

... gamete formation, does the segregation of one pair alleles have any affect on the segregation of a different pair of alleles? In other words, does the gene that determines if a pea plant is tall or dwarf have any affect on the gene for seed color? ...
Coming Off Psychiatric Drugs
Coming Off Psychiatric Drugs

... This guide brings together the best information we’ve discovered and lessons we’ve learned at The Icarus Project and Freedom Center. It is not intended to persuade anyone to stop taking psychiatric medications, but instead aims to educate people about their options if they decide to explore going of ...
Document
Document

... These two alleles are inherited, one parent If the offspring from each _______. receives a dominant allele from one parent, that dominant trait will ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Post operative nausea and vomiting (PONV) are considered as very unpleasant side effects of anaesthesia, causing distress and dissatisfaction to patients. It is multifactorial and despite advances in antiemetic therapy the incidence is high. The main patient related factors are age, gender, history ...
Panel Discussion 3 Questions
Panel Discussion 3 Questions

... 32. The Lynskey article mentioned that cannabis use is higher in the U.S. in the Netherlands, where cannabis was decriminalized in an effort to separate it from the hard drug market. Please comment on this specific example. Are there other examples of places in the world where legislation has been a ...
Genetics ppt - John Adams Academy
Genetics ppt - John Adams Academy

... When the first generation was allowed to self-pollinate (RrYy x RrYy), it resulted in the production of 556 seeds: 315 round, yellow (dominant, dominant) 105 round, green (dominant, recessive) 104 wrinkled, yellow (recessive, dominant) 32 wrinkled, green (recessive, recessive) This meant that the a ...
Fixed combination of arthemether and lumefantrine
Fixed combination of arthemether and lumefantrine

... rapid clinical and parasitological cure; (ii). there is as yet no documented parasite resistance to them; (iii). they reduce gametocyte carrier rates; and (iv). are generally well tolerated (1998, 2001a). There is however limited clinical experience for many of the combinations being considered. It ...
Genetics Powerpoint
Genetics Powerpoint

... These two alleles are inherited, one parent If the offspring from each _______. receives a dominant allele from one parent, that dominant trait will ...
Grapefruit Seed Extract
Grapefruit Seed Extract

The Nebraska Medical Center Guidelines for Management of
The Nebraska Medical Center Guidelines for Management of

... bioavailability, CSF (~50% of serum), and vitreous penetration. Oral bioavailability is not affected by gastric pH but is decreased when consumed with food. IV voriconazole is complexed to a cyclodextrin molecule, and should not be used if the CrCl is < 50 mL/min due to risk of accumulation of this ...
Pravin R - Pivot Pharmaceuticals
Pravin R - Pivot Pharmaceuticals

... Experienced in drug development of antivirals, anti-inflammatory, cancer, hemoglobinopathies, immunosuppression and CNS agents Successfully led to the discovery and IND filing of many novel, first-in-class drugs across various enzyme and ion channel targets Broad experience in global regulatory drug ...
presentation
presentation

... Analysis of variance was used to compare the positive control vs. placebo at each data point and calculate point estimates of the respective two-sided 95% CI for the difference in effects between use of placebo and moxifloxacin. ...
Seretide Accuhaler
Seretide Accuhaler

... of control and patients should be reviewed by a physician. Sudden and progressive deterioration in control of asthma is potentially life-threatening and the patient should be reviewed by a physician. Consideration should be given to increasing corticosteroid therapy. Also, where the current dosage o ...
IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT)
IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT)

... minimum medical needs for a basic healthcare system. Its hydrochloridesalt is sold as KETANEST, KETASET and KETALAR. Pharmacologically, ketamine is classified as an NMDA receptor antagonist.(Harrison and Simmonds, 1985) At high, fully anesthetic level doses, ketamine has also been found to bind to μ ...
B - Dendrome
B - Dendrome

... Quantify and evaluate population dynamics Use software to calculate population parameters based on genetic markers Distinguish strategies for mapping markers and quantitative trait loci Understand marker development and marker-assisted applications Predict and evaluate alternative breeding strategie ...
File
File

... These two alleles are inherited, one parent If the offspring from each _______. receives a dominant allele from one parent, that dominant trait will ...
biotransformation - University of California, Berkeley
biotransformation - University of California, Berkeley

... 2. Electrostatic Interactions: CYP has a positively charged region above the heme moiety that interacts with negatively charged residues on CYP reductase. ...
Pharmacological management for agitation and aggression in
Pharmacological management for agitation and aggression in

... Randomised controlled trials (RCTs) that evaluated the efficacy of drugs acting on the central nervous system for agitation and/or aggression, secondary to ABI, in participants over 10 years of age. Data collection and analysis We independently extracted data and assessed trial quality. Studies of p ...
Research Article Punica granatum Rind, a Traditional Herbal
Research Article Punica granatum Rind, a Traditional Herbal

... wound formed on the skin, which is a common problem faced by the patients of limb paralysis and other long term bed ridden patients. In this research project a traditional herbal medicine, used in Northern part of Saudi Arabia for the treatment of severe condition of open wounds, is studied in male ...
Pharmacotherapeutic action of Dasanga Guggulu
Pharmacotherapeutic action of Dasanga Guggulu

... an effective and less side effective drug for this ailment. Even though there are number of synthetic drugs available in the market, they have considerable side effects such as headache, difficulty in sleeping, flushing of the skin, muscle aches, drowsiness, memory loss etc. So there is a great dema ...
< 1 ... 278 279 280 281 282 283 284 285 286 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report