• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Gene a Pain for Statin Users
Gene a Pain for Statin Users

According to NIDA`s Monitoring the Future Survey, we are seeing
According to NIDA`s Monitoring the Future Survey, we are seeing

... individual health is the result of dynamic interactions between genes and environmental conditions. For example, susceptibility to high blood pressure is influenced by both genetics and lifestyle, including diet, stress, and exercise. Environmental influences, such as exposure to drugs or stress, ca ...
Risk List—DuPont Merck
Risk List—DuPont Merck

... The drugs used in this study may have side effects, some of which are listed below. Please note that these lists do not include all the side effects seen with these drugs. These lists include the more serious or common side effects with a known or possible relationship. If you have questions concern ...
ATTACHMENT I Regulatory Information Number (RIN) :  RIN 0910-AF14
ATTACHMENT I Regulatory Information Number (RIN) : RIN 0910-AF14

... early stage and/or orphan drugs. There is a cancem that this uncontrolled use of the drug by investigators inexperienced in the use of investigational drugs could adversely affect the drug's development, slowing down time to approval and/or result in unfavorable patient outcomes . ...
A1986A667000002
A1986A667000002

... The papers went almost unnoticed before I was invited to present my findings in 1964 at the New York Academy of Sciences. My presentation summarized all my research at the Free University of Berlin, previously published only in German. I could conclusively prove that increased drug metabolism is cau ...
Antitubercular Drugs Nursing Implications
Antitubercular Drugs Nursing Implications

... hypersensitivity response • Two-step testing – health care workers • 5mm > induration – Immunosuppressed patients • 10 mm> “at risk” populations & health are workers • 15 mm> Low risk people – Chest X-ray -- used in conjunction with skin testing • Multinodular lymph node involvement with cavitation ...
Prescribing in the Elderly - Benton Franklin County Medical Society
Prescribing in the Elderly - Benton Franklin County Medical Society

... and the patient received less than the prescribed dose Wrong dose of morphine administered after 4 mg/mL prefilled syringes were replaced with 5 mg/mL vials Cancellations of surgeries and procedures ...
Quiz 2 – (5%) – Using Matlab With a vast number of genes
Quiz 2 – (5%) – Using Matlab With a vast number of genes

AMERICAN SOCIETY OF ANESTHESIOLOGISTS
AMERICAN SOCIETY OF ANESTHESIOLOGISTS

... Anesthesiologists, a scientific and educational organization that represents more than 35,000 physicians across the United States, and which is dedicated to patient sa&etyand quality medical care. My purpose is to urge the Food and Drug Administration to take immediate and appropriate action that wi ...
What`s Inside Worksheet
What`s Inside Worksheet

... 1. What category of drug is yours? (Depressant, Stimulant, Hallucinogens, Opiate..etc) 2. What neurotransmitter does your drug effect? 3. Is your drug an Agonist or Antagonist (does it mimic a neurotransmitter or block a neurotransmitter? 4. What are the physical/physiological effects? 5. How many d ...
02. Factors modifying drug actions
02. Factors modifying drug actions

... IV. Environmental factors Microsomal enzyme inducers e.g., Hydrocarbons in tobacco smoke, charcoal broiled meat induce CYP1A Smokers metabolize drugs more rapidly than non smokers ...
Section: 2-1
Section: 2-1

... myocardial infarction. 2. Under normal circumstances, there is no need for daily monitoring of the effect of Lovenox in patients with normal baseline or presurgical coagulation parameters. 3. Standard monitoring includes: periodic CBC’s, including platelet count and stool occult blood tests. 4. Cont ...
Drug - Trimble County Schools
Drug - Trimble County Schools

... Arises from personal and social factors that act as an escape from personal problems and stressful situations  Produces a conditioned pattern of drug abuse ...
Gliptins: disabling joint pain
Gliptins: disabling joint pain

... effects and any long-term clinical benefits have yet to be proven (2). Gliptins have an unfavourable harm-benefit balance. If a gliptin-treated patient develops joint pain, recognising the drug’s role and stopping this treatment can relieve the pain and avoid exposure to antirheumatic or anti-inflam ...
Can we successfully manage patients on bisphosphonate
Can we successfully manage patients on bisphosphonate

... or impaired recovery of bone-marrow precursors will continue to threaten osseointegration. What should clinicians do when presented with patients who desire dental implant therapy but have been taking Fosamax for several years? A first option is to have the patient tested for the serum marker C-term ...
extrapyramidal reactions - Prescrire International
extrapyramidal reactions - Prescrire International

... effects and any long-term clinical benefits have yet to be proven (2). Gliptins have an unfavourable harm-benefit balance. If a gliptin-treated patient develops joint pain, recognising the drug’s role and stopping this treatment can relieve the pain and avoid exposure to antirheumatic or anti-inflam ...
accessible version
accessible version

... At the commencement of treatment with anti-resorptive or anti-angiogenic drugs, advise the patient (or carer where appropriate): o That the medication they have just been given is associated with a small risk of MRONJ. o To make an appointment with a dentist as soon as possible to ensure they are de ...
Pharmacology Basics
Pharmacology Basics

... Pharmacology Basics ...
Introduction
Introduction

... In low dose it is an Excellent analgesic, but have serious side effects such as: Addiction, tolerance (the effect of the drug diminishes after repeated doses and so we need to increase the size of the dose to achieve the ...
Presentation for zagreb
Presentation for zagreb

...  Usually “brokered” by doctor or pharmacist in response to incentives  Patients are rarely loyal* to a specific drug (even chronic patients go through frequent changes in their medication), but easily scared by remarks made by experts on quality, strength *except in cases where there is a “stand-a ...
B.P.T. [2 Prof.] Pharmacology
B.P.T. [2 Prof.] Pharmacology

... Antiretro virus drugs should be given in combination. Anticholinergic drug's main side effects is dryness of mouth. Diabetic patients who are taking Insulin should avoid Alcohol drink. In variant Angina beta - blockers are avoided. On and off phenomenon occurs after chronic use of Levodopa in Parkin ...
10 General Pharmacology
10 General Pharmacology

... Chapter 10 ...
PATIENT`S NAME: MEDICATION - McGraw-Hill
PATIENT`S NAME: MEDICATION - McGraw-Hill

... (such as warmth, redness, pain or swelling in your calf), chest pain, difficulty breathing or shortness of breath, sudden vision changes or other vision disturbances, severe headache, weakness on one side of your body, or slurred speech. Report bloating, rash, yellowing of eyes or skin, and depressi ...
The US Pharmaceutical Industry (Why Do Drugs Cost So Much?
The US Pharmaceutical Industry (Why Do Drugs Cost So Much?

... – safety and pharmacokinetics • Phase 2 (patients -small number) – initial assessment of pharmacological effect – safety and pharmacokinetics in patients – drug metabolism • Phase 3 (patients -large number) – definitive demonstration of efficacy • Phase 4 – studies required as a condition of FDA app ...
Drug development
Drug development

... • BIOLOGICAL; acute pharmacological profile LD50, ED50, binding data for many receptors, dose-effect relationships, open field tests, particular tests for different activities (e.g. CVS, CNS, GI tract) Both positive and negative information is useful. ...
< 1 ... 1238 1239 1240 1241 1242 1243 1244 1245 1246 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report