• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Nasal Drug Delivery in EMS
Nasal Drug Delivery in EMS

... burn, orthopedic trauma and visceral pain in both adults and children showing the following: ...
Chapter 11.2 (Pg. 313-318): Applying Mendel*s Principles
Chapter 11.2 (Pg. 313-318): Applying Mendel*s Principles

... event will occur - Can be predicted in genetics through segregation - Assumes that each gamete has a ½ chance of carrying an allele ...
Glioblastoma Multiforme (GBM) – Subtype Analysis
Glioblastoma Multiforme (GBM) – Subtype Analysis

... – Affymetrix software does some of this with Present/Absent calls – Fold-change filter? – Other methods? ...
chapter 4 psychopharmacology
chapter 4 psychopharmacology

... – Must be synthesized within the neuron – In response to an action potential, the substance is released in sufficient quantities to produce an effect in the postsynaptic cell – We should be able to duplicate the action of a suspected neurotransmitter experimentally on a postsynaptic cell – Some mech ...
SHEET L.12 SLIDE 4(Strategies to reduce medication
SHEET L.12 SLIDE 4(Strategies to reduce medication

...  Other than the high alert medications, we should also know a group of drugs called Beer's drugs  High alert medications aren't related to age  There is a group of medications which are considered unsafe for geriatric patients; they're mentioned in the American geriatric society  There is someth ...
Equianalgesic Chart (Page 1)
Equianalgesic Chart (Page 1)

... OXYMORPHONE (Numorphan) ...
Greig Syndrome - City Tech OpenLab
Greig Syndrome - City Tech OpenLab

... frequency of GCPS in the general population. According to the National Organization for Rare Diseases (NORD), GCPS affects males and females equally. There have been over 200 patients reported in medical history with this disorder. However, because some affected individuals may express fewer symptom ...
USE OF GENOMICS AND PROTEOMICS IN PHARMACEUTICAL DRUG DISCOVERY AND
USE OF GENOMICS AND PROTEOMICS IN PHARMACEUTICAL DRUG DISCOVERY AND

... discovery involves the identification of candidates, synthesis, characterization, screening, and assays for therapeutic efficacy. The process of drug development prior to clinical trials begins, when a compound has shown its value in the above tests. The process is generally quite tedious and expens ...
Potentially inappropriate drug use and hip
Potentially inappropriate drug use and hip

... 50% of drugs, severe adverse effects identified after approval 10% restricted use 3% of drugs withdrawn ...
Strategies for Safely Managing Patients on Warfarin November 4
Strategies for Safely Managing Patients on Warfarin November 4

... – establish the practice standard that all long-term anticoagulation patients should be cared for in a program with the essential elements of an AMMS – promote the use of ST and SM among selected patients - support improvement in time in therapeutic range in AMMS’s and across transitions ...
Liver diease
Liver diease

... No active or passive immunization available Treatment is only suggested in certain subgroups, but it is expensive, takes up to 1 year, has many side effects, and only 10-30% are actually cured ...
EVALUATION OF crude drugs
EVALUATION OF crude drugs

... identifying particular drugs. • Examples: Halpher’s test for cotton seed oil. ...
Module 2: Drug and Alcohol Awareness
Module 2: Drug and Alcohol Awareness

... alcohol? Make a list of the reasons why, the benefits, and if there are any, some of the less good aspects of these habits. • why do people with mental health problems use drugs and alcohol? Make a list of the reasons that you are aware of from what service users have told you, or assumptions that y ...
Remain Alert to Black Box Warnings
Remain Alert to Black Box Warnings

... This case was settled for a high dollar amount. ...
Genes and Evolution
Genes and Evolution

... This is like taking all of the alleles in the population and drawing them two at a time to determine the genotype for each F1 individual. ...
Codeine Therapy in the Context of Cytochrome P450 2D6
Codeine Therapy in the Context of Cytochrome P450 2D6

... appear to affect response to hydrocodone.24,25 To date, there is no information on the pharmacokinetics of hydrocodone in CYP2D6 ultrarapid metabolizers. Therefore, there is insufficient evidence as to whether poor metabolizers can be expected to have decreased analgesia when treated with hydrocodon ...
Adenosine - Wellington ICU
Adenosine - Wellington ICU

... Mechanism of Action - depression of SA & AV nodal activity - antagonises cAMP-mediated catecholamine stimulation of ventricular muscle -> negative chronotropy & dromotropy - direct agonist at specific cell membrane receptors (A1 & A2) - A1 = coupled to K+ channels by a guanine nucleotide-binding pro ...
amiodarone hydrochloride - McGraw-Hill
amiodarone hydrochloride - McGraw-Hill

... ● Advise patient to take oral doses at meals with 8 oz of water. ● Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness. ● Tell patient to minimize GI upset by eating small, frequent servings of food and drinking plenty of fluids ...
Genetics Study Guide
Genetics Study Guide

... 4 Rr x Rr is an example of what type of cross ----- P1, F1, or F2? 5 If both alleles are the same in a genotype, is the genotype homozygous or heterozygous? 6 Which cross is a cross between two hybrids ----- P1, F1, or F2? 7 __________ dominance results in the blending of genes in the hybrid. Give a ...
Inheritance and Genetics
Inheritance and Genetics

... learned that offspring usually had dominate trait ...
Put your Medication where your Mouth is.
Put your Medication where your Mouth is.

... Assess medication allergies ...
measuring adherence
measuring adherence

... Compliance as a partnership between patients, physicians and even managed care to achieve desired health outcomes – now called “concordance”. Managing medication compliance = improved outcomes complex, but, interesting implications for health practitioners ...
Medicinal Chemistry - Millennium Organization
Medicinal Chemistry - Millennium Organization

Campbell Ch 14 Reading guide
Campbell Ch 14 Reading guide

... to the F2 generations. _____________________________________________________________________ _____________________________________________________________________ 6. When does the segregation of alleles occur? __________________________________ ...
Genes and Inheritance
Genes and Inheritance

... the ones that are easily hidden. They take a back seat to the dominant ones. The only time you will see a recessive trait is if there is no dominant one to take over. ...
< 1 ... 1113 1114 1115 1116 1117 1118 1119 1120 1121 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report