• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
MD0804 10-1 LESSON ASSIGNMENT LESSON 10 Central Nervous
MD0804 10-1 LESSON ASSIGNMENT LESSON 10 Central Nervous

... into the lungs. Two, they stimulate the central nervous system and produce diuresis (they increase the production of urine) by direct action on the kidney. There are several examples of xanthine derivatives: (1) Caffeine. Caffeine is found in coffee, tea, and in kola nuts (used to make some soft dri ...
Chapter 7 – Are You Only as Smart as Your Genes
Chapter 7 – Are You Only as Smart as Your Genes

... Chapter 7 – Are You Only as Smart as Your Genes ...
Module 5
Module 5

... People with mental health problems • 30% of patients have mental health problems, including anxiety and depression • 25% risk of self harm and suicide • 10% severe mental disorders requiring collaboration with mental health specialists • Note age- or HIV-related dementia ...
CYP2D6 - PGXL Laboratories
CYP2D6 - PGXL Laboratories

Experimental Study Designs
Experimental Study Designs

... More drop outs because of time involved. Study design is very sensitive to drop outs since small number of patients involved. Period effects Sequence effects Carry over effects ...
Pain Management
Pain Management

... *Clonazepam (Clonopin®) and/or lorazepam (Ativan®) may be detected at higher concentrations (>3000 ng/mL); for patients prescribed these drugs test 763910 is also recommended. ...
No Slide Title
No Slide Title

... recombination frequencies not always perfect ...
Opiates
Opiates

... arousal) is reduced Headache? Vasoconstrictor normally, but expands vascular areas when off of it Deadly overdose? Rare, caffeine poisoning occurs first, probably in concert with pre-existing health problems Can have some other negative effects (don’t use in expectant mothers, pregnant mothers) ...
File
File

...  Infant’s body weight – 25% muscle  Adult’s body weight – 40% muscle  Children has smaller muscle mass – fewer sites are available for IM injection  Blood flow to muscles in young children is variable and may also affect absorption of injected medications ...
Carbamazepine Toxicity - Anticonvulsant structurally similar to TCA`s
Carbamazepine Toxicity - Anticonvulsant structurally similar to TCA`s

... minutes quickly relieves cyanosis due to methemoglobinemia. Intravenous methylene blue is indicated for methemoglobin fractions over 30% and at lower fractions in patients with anemia or cardiovascular disease. The dose may be repeated if no clinical response is observed within 1 hour. A dose greate ...
Slide 1
Slide 1

... expresses volume that would occupate particles of the whole given dose of substance, if they would be „inflated“ or „diluted“ the same as in tested sample Vd = D/C0 - only fictive value – it gives idea about the distribution of substance in organism rate constant of absorption (ka) a elimination (ke ...
Human Genetics
Human Genetics

... PP and Pp = normal; pp = PKU  build up causes mental retardation  Babies tested; those w/ PKU not given phenylalanine in diet. deterioration ___ of CNS Tay-sachs disease: causes death by _____________ ____ from lack of enzyme to breakdown fatty deposits on nerve and brain cells. ...
Pain Assessment Documentation Tool
Pain Assessment Documentation Tool

... current pain reliever(s) is Better, the Same, or Worse since  the patient’s last assessment with the PADT.*  (Please  check the box for Better, Same, or Worse for each item  below.)  ...
Focus on regulatory points
Focus on regulatory points

...  Communication  Focus on regulatory points  Pharmacoeconomy ...
MUSCARINIC RECEPTOR ANTAGONISTS:
MUSCARINIC RECEPTOR ANTAGONISTS:

EpiStem Plc (LSE: EHP), the UK epithelial stem cell company
EpiStem Plc (LSE: EHP), the UK epithelial stem cell company

... (ROS)-generation preventing effects, and with immunosuppressive and wound-healing properties. ROS are produced during cellular metabolism, but have the capacity to damage cells. ...
100908 Gen Pharm (pt 2).
100908 Gen Pharm (pt 2).

07:04, 7 August 2010
07:04, 7 August 2010

... Orthologs (Compara/Inparanoid) Mining InterPro Monocots ...
Levsin SL PI RA - Meda Pharmaceuticals
Levsin SL PI RA - Meda Pharmaceuticals

... cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These peripheral cholinergic receptors are present in the autonomic effector cells of the smooth muscle, cardiac muscle, the sinoatrial node, the atrioventricular node, and the exocrine glands. A ...
Phil Rowe Reader in pharmaceutical computing School of
Phil Rowe Reader in pharmaceutical computing School of

... excreted via the kidneys. If renal function is normal, creatinine is cleared quickly and blood levels remain low in renal disease creatinine levels increase. 'Creatinine clearance' therefore used as a marker of renal function. If creatinine clearance is (say) 50% of normal, then renally cleared drug ...
Document
Document

... Medical errors lead to excess costs ($ 37 B/year in the US), health injury Medical errors are preventable in large scale (at least in 50 %) but in some cases new approaches are needed ...
Dear MP
Dear MP

... outcomes. We are all affected. Fear of discrimination can discourage people from making decisions about genetic testing which may give an individual the opportunity to be proactive about health matters or enable then to participate in clinical research. Fear of genetic discrimination is a barrier to ...
The New World of Clinical Genomics
The New World of Clinical Genomics

... give sufficient linkage information. As demonstrated by Dauber et al. (6), by using MPS, one can identify potential pathogenic sequence variants with a single family with just two affected individuals. However, because MPS does not limit the region of interest as did meiotic mapping, it identifies t ...
SUBSTANCE USE EVALUATION (ALCOHOL AND DRUGS)
SUBSTANCE USE EVALUATION (ALCOHOL AND DRUGS)

... As of this date, I certify that I have reviewed Section 1 and completed Section 2 and that this Substance Use Evaluation is true to the best of my knowledge and belief based on information obtained from the client, the client’s known substance use disorder and mental health history, and a client exa ...
Antibody-Drug Conjugates
Antibody-Drug Conjugates

... Member of the Roche Group (March 2009) Leading biotechnology company : treatment of patients with life-threatening medical conditions ...
< 1 ... 1109 1110 1111 1112 1113 1114 1115 1116 1117 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report