Heavy Chain Diversity Region Segments of the Channel Catfish
... DH gene segments encode only limited CDR3 structural diversity. Studies with the channel catfish have provided insight into the early evolutionary patterns of Ig gene organization and genetic diversity. The genomic organization of H chain gene segments in the catfish, a teleost (bony) fish, is diffe ...
... DH gene segments encode only limited CDR3 structural diversity. Studies with the channel catfish have provided insight into the early evolutionary patterns of Ig gene organization and genetic diversity. The genomic organization of H chain gene segments in the catfish, a teleost (bony) fish, is diffe ...
PDF
... because the first intron tends to be longer than average10. Moreover, if the start codon occurs very close to the splice-donor site, the coding portion may be too small to be identified by currently available gene-finding programs. In these cases, we have no way of knowing where the promoter is loca ...
... because the first intron tends to be longer than average10. Moreover, if the start codon occurs very close to the splice-donor site, the coding portion may be too small to be identified by currently available gene-finding programs. In these cases, we have no way of knowing where the promoter is loca ...
Alu
... The history of substitution patterns in the human genome Markers to determine genetic distances between human subpopulations – polymorphic Alu insertions ...
... The history of substitution patterns in the human genome Markers to determine genetic distances between human subpopulations – polymorphic Alu insertions ...
Application Note: Targeted sequencing and chromosomal haplotype
... are tens of kilobases in length. The Targeted Locus Amplification (TLA) Technology1 from Cergentis enables the targeted, hypothesis-neutral, amplification of any genomic locus of interest over 50 kb using just one primer pair complementary to a short locusspecific sequence. TLA is a strategy to sele ...
... are tens of kilobases in length. The Targeted Locus Amplification (TLA) Technology1 from Cergentis enables the targeted, hypothesis-neutral, amplification of any genomic locus of interest over 50 kb using just one primer pair complementary to a short locusspecific sequence. TLA is a strategy to sele ...
Genetics of Male Infertility - the Infertility Center of St. Louis
... first attempts at constructing a physical map with YAC’s, because repetitive STS’s could not be accurately placed in what was then called deletion intervals 6D-6F. Even the size of AZFc (without an accurate sequence) was controversial (0.5 to 2 Mb) (62,105-106). Efforts to find point mutations along ...
... first attempts at constructing a physical map with YAC’s, because repetitive STS’s could not be accurately placed in what was then called deletion intervals 6D-6F. Even the size of AZFc (without an accurate sequence) was controversial (0.5 to 2 Mb) (62,105-106). Efforts to find point mutations along ...
as a PDF - CiteSeerX
... not altered by pms1, msh2, and msh3 mismatch repair mutations. Similar to our previous observations for replication slippage-mediated deletions, there were >5-bp identical runs at the recombination breakpoints. We propose that the dramatic increase in recombination results from enhancement of the ef ...
... not altered by pms1, msh2, and msh3 mismatch repair mutations. Similar to our previous observations for replication slippage-mediated deletions, there were >5-bp identical runs at the recombination breakpoints. We propose that the dramatic increase in recombination results from enhancement of the ef ...
PDF manual - QIAGEN Bioinformatics
... length fraction" and "Minimum similarity fraction" settings will be used only for the mapping of all entries in sequence lists where one or more of the reads is 56bp or longer. The mapping parameters are: • Maximum number of mismatches. This parameter is available if you have selected at least one s ...
... length fraction" and "Minimum similarity fraction" settings will be used only for the mapping of all entries in sequence lists where one or more of the reads is 56bp or longer. The mapping parameters are: • Maximum number of mismatches. This parameter is available if you have selected at least one s ...
PDF
... mechanisms that regulate this process are not completely understood in any eukaryotic system, many advances have been made recently with regard to the regulation of the mammalian Ig heavy-chain genes expressed in B cells as well as the odorant receptor gene family expressed in olfactory sensory neur ...
... mechanisms that regulate this process are not completely understood in any eukaryotic system, many advances have been made recently with regard to the regulation of the mammalian Ig heavy-chain genes expressed in B cells as well as the odorant receptor gene family expressed in olfactory sensory neur ...
New Construct Approaches for Efficient Gene Silencing in Plants
... of the terminator-free expression cassette on the neighboring hptII gene was confirmed by carrying out realtime PCR. Figure 3B shows similar levels of hptII transcript for 6-week-old pSIM374 and 717 plants that displayed gus gene silencing. Each group of plants contained one individual with a lower ...
... of the terminator-free expression cassette on the neighboring hptII gene was confirmed by carrying out realtime PCR. Figure 3B shows similar levels of hptII transcript for 6-week-old pSIM374 and 717 plants that displayed gus gene silencing. Each group of plants contained one individual with a lower ...
PDF - Journal of Genomics
... acids and carbohydrates that are abundant in their phloem-based diet or produced by the host. Genomic evidence suggests that several amino acid biosynthetic pathways are shared between aphid and Buchnera, providing the aphid the ability to regulate the endosymbiont’s metabolism (16). No aphid specie ...
... acids and carbohydrates that are abundant in their phloem-based diet or produced by the host. Genomic evidence suggests that several amino acid biosynthetic pathways are shared between aphid and Buchnera, providing the aphid the ability to regulate the endosymbiont’s metabolism (16). No aphid specie ...
Mining Multi-Faceted Overviews of Arbitrary Topics in a Text Collection
... regardless of whether it contains any extra information. • To study how different methods affect the final generated summary, we evaluated them based on the precision of best five sentences for each facet separately. • The results are shown in Table 2 and 4. ...
... regardless of whether it contains any extra information. • To study how different methods affect the final generated summary, we evaluated them based on the precision of best five sentences for each facet separately. • The results are shown in Table 2 and 4. ...
Establishment of new mutations under divergence and genome
... islands or continents? Empirical genome scan studies have provided evidence for the island view of divergence ([18]; for review [32,54]). In contrast, evidence for more widespread divergence is rarer (but see [51,55]). However, this may stem from strong limitations in relying on genome scans alone f ...
... islands or continents? Empirical genome scan studies have provided evidence for the island view of divergence ([18]; for review [32,54]). In contrast, evidence for more widespread divergence is rarer (but see [51,55]). However, this may stem from strong limitations in relying on genome scans alone f ...
Triple-hit lymphoma
... estimated to be approximately 2% of all B-cell lymphomas (5). The median survival time is reported to be about 5 months, significantly shorter than for either DLBCL or BL (6). Triple-hit lymphomas have been infrequently reported, with only a small number of case reports noted. These lymphomas are rar ...
... estimated to be approximately 2% of all B-cell lymphomas (5). The median survival time is reported to be about 5 months, significantly shorter than for either DLBCL or BL (6). Triple-hit lymphomas have been infrequently reported, with only a small number of case reports noted. These lymphomas are rar ...
SVPaper050711
... Table 8) where a SNP and SV formation co-segregate. We found a similar relationship between a SNP formed at a target site duplication and the presence of an ancestral insertion. Fifteen ancestral insertions (16%) had SNPs or short indels within their target site duplication, coincident with the inse ...
... Table 8) where a SNP and SV formation co-segregate. We found a similar relationship between a SNP formed at a target site duplication and the presence of an ancestral insertion. Fifteen ancestral insertions (16%) had SNPs or short indels within their target site duplication, coincident with the inse ...
Gene conversion and purifying selection shape nucleotide variation
... However, nucleotide variation of both introns and exons among catarrhines has only been examined in detail for the L opsin gene of humans and chimpanzees. In the present study, we examined the nucleotide variation of gibbon (Catarrhini, Hylobatidae) L and M opsin genes. Specifically, we focused on t ...
... However, nucleotide variation of both introns and exons among catarrhines has only been examined in detail for the L opsin gene of humans and chimpanzees. In the present study, we examined the nucleotide variation of gibbon (Catarrhini, Hylobatidae) L and M opsin genes. Specifically, we focused on t ...
Structural changes following the reversal of a Y chromosome to an
... translocation. Our results suggest that genetic drift and a small ancestral Y chromosome may also help explain the compact size of the Y-to-dot translocation. Key words: evolution, SMRT sequencing, PacBio, Y chromosome, dot chromosome ...
... translocation. Our results suggest that genetic drift and a small ancestral Y chromosome may also help explain the compact size of the Y-to-dot translocation. Key words: evolution, SMRT sequencing, PacBio, Y chromosome, dot chromosome ...
Guidelines for interpretation of 16S rRNA gene sequence
... sequence homogeneity in different strains of that species becomes very important in determining whether 16S rRNA gene sequencing is able to identify the bacterium to the species level. More importantly, medically important bacterial species with similar 16S rRNA gene sequences were also identified ( ...
... sequence homogeneity in different strains of that species becomes very important in determining whether 16S rRNA gene sequencing is able to identify the bacterium to the species level. More importantly, medically important bacterial species with similar 16S rRNA gene sequences were also identified ( ...
No more than 14: the end of the amphioxus Hox cluster
... considerable interest to establish the limits of its Hox gene cluster, namely resolution of whether more Hox genes are present in the single amphioxus Hox cluster (e.g., Hox 15). Using two strategies, we show here that the amphioxus Hox cluster (up to AmphiHox14) is linked to AmphiEvx, and that ther ...
... considerable interest to establish the limits of its Hox gene cluster, namely resolution of whether more Hox genes are present in the single amphioxus Hox cluster (e.g., Hox 15). Using two strategies, we show here that the amphioxus Hox cluster (up to AmphiHox14) is linked to AmphiEvx, and that ther ...
Drosophila Muller F Elements Maintain a Distinct Set of Genomic
... and additional resources supporting the GEP annotation protocol are available on the GEP web site (http://gep.wustl.edu). Each annotation project was completed independently by at least two GEP students. The GEP staff supervised students who reconciled the submitted annotations using the Apollo Gen ...
... and additional resources supporting the GEP annotation protocol are available on the GEP web site (http://gep.wustl.edu). Each annotation project was completed independently by at least two GEP students. The GEP staff supervised students who reconciled the submitted annotations using the Apollo Gen ...
Direct and indirect consequences of meiotic recombination
... has also been discussed [20]. We refer to these processes as the direct effects of recombination (further details are presented in Box 1 and Figure 1). Although one of the advantages of the indirect effects of recombination is the efficient removal of deleterious alleles from a population, its direc ...
... has also been discussed [20]. We refer to these processes as the direct effects of recombination (further details are presented in Box 1 and Figure 1). Although one of the advantages of the indirect effects of recombination is the efficient removal of deleterious alleles from a population, its direc ...
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)
... which can be differentiate from other Aeromonas sp. as it can produce gas from glucose but does not hydrolyze esculin [12], whereas, other Aeromonas sp. produce gas from glucose and hydrolyze esculin. Similar identification protocols for identification of Aeromonas sp. were also followed by other re ...
... which can be differentiate from other Aeromonas sp. as it can produce gas from glucose but does not hydrolyze esculin [12], whereas, other Aeromonas sp. produce gas from glucose and hydrolyze esculin. Similar identification protocols for identification of Aeromonas sp. were also followed by other re ...
Bis2A 16.2 Errors in Meiosis
... one copy of an autosome invariably fail to develop to birth because they have only one copy of essential genes. Most autosomal trisomies also fail to develop to birth; however, duplications of some of the smaller chromosomes (13, 15, 18, 21, or 22) can result in ospring that survive for several wee ...
... one copy of an autosome invariably fail to develop to birth because they have only one copy of essential genes. Most autosomal trisomies also fail to develop to birth; however, duplications of some of the smaller chromosomes (13, 15, 18, 21, or 22) can result in ospring that survive for several wee ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.