Number 48, 2001 35
... agreement with this possibility, a low frequency of mutants for loci covered by the duplication was observed, amongst the survivors (Perkins et al. 1997 Genetics 147:125-136). In addition, molecular analysis of a few mutant alleles generated by RIP in a segmental duplication indicated a very low GC- ...
... agreement with this possibility, a low frequency of mutants for loci covered by the duplication was observed, amongst the survivors (Perkins et al. 1997 Genetics 147:125-136). In addition, molecular analysis of a few mutant alleles generated by RIP in a segmental duplication indicated a very low GC- ...
Hemoglobin A2: origin, evolution, and aftermath
... gene are depicted in Table 1. Although these likely arose from a nonhomologous crossing over event in variants may be unstable or have elevated oxygen affinity, which the P-globin gene from one chromosome mispaired they are not associated with a clinically significant phenowith the &globin gene of t ...
... gene are depicted in Table 1. Although these likely arose from a nonhomologous crossing over event in variants may be unstable or have elevated oxygen affinity, which the P-globin gene from one chromosome mispaired they are not associated with a clinically significant phenowith the &globin gene of t ...
X chromosome inactivation- Review
... region in Xist gene and is required for X inactivation Model- Mutually exclusive binding of blocking factor to Xce on one X, and of initiator factor to Xist on other X Marsupials and in mice extraembyonic tissues- paternal X always inactivated in females ...
... region in Xist gene and is required for X inactivation Model- Mutually exclusive binding of blocking factor to Xce on one X, and of initiator factor to Xist on other X Marsupials and in mice extraembyonic tissues- paternal X always inactivated in females ...
Cytogenetics
... Results from errors in division during meiosis, where a daughter cell receives both pairs of a particular chromosome (nondisjunction errors). Addition of an extra chromosome, trisomy, has been described for all the chromosomes but only three autosomal trisomies survive to birth. Those are trisomies ...
... Results from errors in division during meiosis, where a daughter cell receives both pairs of a particular chromosome (nondisjunction errors). Addition of an extra chromosome, trisomy, has been described for all the chromosomes but only three autosomal trisomies survive to birth. Those are trisomies ...
alpha-amylase from bacillus licheniformis
... The α-amylase described in this document is a genetically engineered enzyme that is thermo-stable and active at a relatively low pH and low calcium concentration. These characteristics make the enzyme particularly suitable for use in starch hydrolysis conducted at high temperatures, for example, for ...
... The α-amylase described in this document is a genetically engineered enzyme that is thermo-stable and active at a relatively low pH and low calcium concentration. These characteristics make the enzyme particularly suitable for use in starch hydrolysis conducted at high temperatures, for example, for ...
Tandem Genetic Duplications in Phage and Bacteria
... General Methods for Detecting Tandem Duplications Selection schemes designed to detect tandem duplication mutants in a haploid population must capitalize upon some special property conferred by the diploid state. The merodiploid nature of tandem duplications and the sequence impropriety found at the ...
... General Methods for Detecting Tandem Duplications Selection schemes designed to detect tandem duplication mutants in a haploid population must capitalize upon some special property conferred by the diploid state. The merodiploid nature of tandem duplications and the sequence impropriety found at the ...
Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1a/tcf1
... genes were shown to be expressed abundantly in liver, pancreas, gut and kidney. Zebrafish HNF1a and HNF1h proteins contain all HNF1 signature domains including the dimerization domain, POU-like domain and atypical homeodomain. Sequence and phylogenetic analysis reveals that zebrafish hnf1a is closer ...
... genes were shown to be expressed abundantly in liver, pancreas, gut and kidney. Zebrafish HNF1a and HNF1h proteins contain all HNF1 signature domains including the dimerization domain, POU-like domain and atypical homeodomain. Sequence and phylogenetic analysis reveals that zebrafish hnf1a is closer ...
出國報告電子檔規格
... two samples are normal fallopian tube tissues. To infer the DNA copy number from the raw signal data, we used the Hidden Markov Model (31), based on the assumption of diploid for normal samples. Mapping information of SNP locations and cytogenetic bands were based on curation of Affymetrix and Univ ...
... two samples are normal fallopian tube tissues. To infer the DNA copy number from the raw signal data, we used the Hidden Markov Model (31), based on the assumption of diploid for normal samples. Mapping information of SNP locations and cytogenetic bands were based on curation of Affymetrix and Univ ...
Evolution of the Actin Gene Family in Testate Lobose Amoebae
... et al. 2006), the breadth of knowledge on actin diversity is largely limited to organisms with completed genomes (Reisler and Egelman 2007). In addition, diverse lineages such as dinoflagellates (Bachvaroff and Place 2008), Foraminifera (Flakowski et al. 2006), and red algae (Wu et al. 2009) have be ...
... et al. 2006), the breadth of knowledge on actin diversity is largely limited to organisms with completed genomes (Reisler and Egelman 2007). In addition, diverse lineages such as dinoflagellates (Bachvaroff and Place 2008), Foraminifera (Flakowski et al. 2006), and red algae (Wu et al. 2009) have be ...
A Fine Physical Map of Arabidopsis thaliana Chromosome 5
... clones CIC11D9 and CIC6A9 have already been mapped on contig IV of chromosome 4.9 A PI clone, MJO17, containing the PDC1 gene also has the ATH1 gene24 which is used as a characterization marker of chromosome 4 and has also been mapped on CIC11D9 and CIC6A9.9 Therefore, we concluded that the PDC1 gen ...
... clones CIC11D9 and CIC6A9 have already been mapped on contig IV of chromosome 4.9 A PI clone, MJO17, containing the PDC1 gene also has the ATH1 gene24 which is used as a characterization marker of chromosome 4 and has also been mapped on CIC11D9 and CIC6A9.9 Therefore, we concluded that the PDC1 gen ...
Prothrombin Gene Mutation - Hamilton Health Sciences
... the body will make too much of the prothrombin protein. This makes the blood more likely to clot. • One or both parents can pass on the prothrombin gene mutation to their child. ...
... the body will make too much of the prothrombin protein. This makes the blood more likely to clot. • One or both parents can pass on the prothrombin gene mutation to their child. ...
Visualization, description and analysis of the Drosophila melanogaster
... evolutionary process. On one hand, the molecule is intrinsically mutable, being this the origin of genetic variation. On the other hand, it allows the replication of old and new variants from one generation to another. The reproductive or survival advantage or disadvantage an individual has for carr ...
... evolutionary process. On one hand, the molecule is intrinsically mutable, being this the origin of genetic variation. On the other hand, it allows the replication of old and new variants from one generation to another. The reproductive or survival advantage or disadvantage an individual has for carr ...
PW_dp
... – accounts for heterogeneity in gene – Immediate gene-level interpretation •Cons: – disregards regulatory (often non-genic) information when based on location based ...
... – accounts for heterogeneity in gene – Immediate gene-level interpretation •Cons: – disregards regulatory (often non-genic) information when based on location based ...
First genomic insights into members of a candidate bacterial
... microorganisms (Hulshoff Pol et al., 2004; Li et al., 2008; Yamada & Sekiguchi, 2009) and a phylogenetically novel filament was previously reported to be the cause of bulking in an industrial UASB reactor treating sugar manufacturing wastewater (Yamada et al., 2007; Yamada et al., 2011). Small subun ...
... microorganisms (Hulshoff Pol et al., 2004; Li et al., 2008; Yamada & Sekiguchi, 2009) and a phylogenetically novel filament was previously reported to be the cause of bulking in an industrial UASB reactor treating sugar manufacturing wastewater (Yamada et al., 2007; Yamada et al., 2011). Small subun ...
The photosynthetic apparatus of Prochlorococcus
... strains MED4 and MIT9313 (details see http://spider.jgipsf.org/JGI_microbial/html/prochlorococcus_homepage.html), has begun to reveal some interesting features of the genetic inventory of this unusual cyanobacterium. These data provide a window into the evolutionary processes that formed the photosy ...
... strains MED4 and MIT9313 (details see http://spider.jgipsf.org/JGI_microbial/html/prochlorococcus_homepage.html), has begun to reveal some interesting features of the genetic inventory of this unusual cyanobacterium. These data provide a window into the evolutionary processes that formed the photosy ...
Journal of Bacteriology
... with the Foscm-TCF and Foscm-TCR primers bearing 70-bp side arms that bind to the flanking regions of the cat gene of pCC1fos. For inactivation of the pmxE gene, a chloramphenicol resistance gene-kanamycin resistance gene (cat-kan) cassette was introduced into the pmxE structural gene of pPmx-Tc usi ...
... with the Foscm-TCF and Foscm-TCR primers bearing 70-bp side arms that bind to the flanking regions of the cat gene of pCC1fos. For inactivation of the pmxE gene, a chloramphenicol resistance gene-kanamycin resistance gene (cat-kan) cassette was introduced into the pmxE structural gene of pPmx-Tc usi ...
Detecting copy number variants and runs of homozygosity on a
... the underlying mechanisms to many common diseases. CNVs are defined as chromosomal segments, at least 1000 bases in length that vary in copy number (CN) between individuals1. A second major contributor to human variation is at the resolution of a single base. Single nucleotide polymorphisms (SNPs) a ...
... the underlying mechanisms to many common diseases. CNVs are defined as chromosomal segments, at least 1000 bases in length that vary in copy number (CN) between individuals1. A second major contributor to human variation is at the resolution of a single base. Single nucleotide polymorphisms (SNPs) a ...
Potato Genome Sequencing Consortium: Final
... really start in earnest until 2008, due to delays in securing funding. The genome of the potato, in common with other organisms, is comprised of a series of ‘bases’ often referred to by the letters A, C, T and G that are linked together in ‘strings’ called chromosomes. One copy of the potato genome ...
... really start in earnest until 2008, due to delays in securing funding. The genome of the potato, in common with other organisms, is comprised of a series of ‘bases’ often referred to by the letters A, C, T and G that are linked together in ‘strings’ called chromosomes. One copy of the potato genome ...
outline4003
... Deep stromal opacities made of amyloid Mutation localized to the BIGH3 gene on chromosome 5 (5q3) Combined Granular and Lattice Dystrophy (Avellino Dystrophy) Granular and lattice type changes in the same eye Hyaline and amyloid deposits in stroma Granular changes early onset; lattice changes occur ...
... Deep stromal opacities made of amyloid Mutation localized to the BIGH3 gene on chromosome 5 (5q3) Combined Granular and Lattice Dystrophy (Avellino Dystrophy) Granular and lattice type changes in the same eye Hyaline and amyloid deposits in stroma Granular changes early onset; lattice changes occur ...
Beyond The Classical Cystic Fibrosis
... Besides the classical form of severe disease, other clinical forms of CF have been identified and called “atypical” forms. These one show monosymptomatic phenotype (recurrent pancreatitis, congenital bilateral agenesis of the vas deferens, asthma, bronchiectasis) and benign prognosis than the classi ...
... Besides the classical form of severe disease, other clinical forms of CF have been identified and called “atypical” forms. These one show monosymptomatic phenotype (recurrent pancreatitis, congenital bilateral agenesis of the vas deferens, asthma, bronchiectasis) and benign prognosis than the classi ...
Exceptionally high levels of recombination
... Scientifique, F91198 Gif-sur-Yvette, France; 5Department of Biology, University of North Carolina, Greensboro, North Carolina 27403, USA; 6Department of Biology, University of Oulu 90014, Finland; 7Department of Environmental Biology, University of Guelph, Ontario N1G 2W1, Canada; 8School of Life Sc ...
... Scientifique, F91198 Gif-sur-Yvette, France; 5Department of Biology, University of North Carolina, Greensboro, North Carolina 27403, USA; 6Department of Biology, University of Oulu 90014, Finland; 7Department of Environmental Biology, University of Guelph, Ontario N1G 2W1, Canada; 8School of Life Sc ...
Genome-Wide Copy Number Variation in Epilepsy: Novel
... reported in the 2493 unrelated controls [24]. The rare CNVs detected in our cohort range in size from 13 kb to 15.9 Mb (average 1.2 Mb; median 600 kb), and the majority (69%) are deletion events. ...
... reported in the 2493 unrelated controls [24]. The rare CNVs detected in our cohort range in size from 13 kb to 15.9 Mb (average 1.2 Mb; median 600 kb), and the majority (69%) are deletion events. ...
H4K20me1 Contributes to Downregulation of X
... condensation and resolution in mitosis and meiosis, and participate in crossover control during meiosis [4]. Four subunits (MIX1, DPY-26, DPY-28, and CAPG-1) are shared with canonical condensin I, while DPY-27 is specific to condensin IDC [5]. The central role of a condensin-like complex in dosage c ...
... condensation and resolution in mitosis and meiosis, and participate in crossover control during meiosis [4]. Four subunits (MIX1, DPY-26, DPY-28, and CAPG-1) are shared with canonical condensin I, while DPY-27 is specific to condensin IDC [5]. The central role of a condensin-like complex in dosage c ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.