Parallel Evolution of Copy-Number Variation across Continents in
... selection, confidence in the biological relevance of such differentiation can be increased by asking whether differentiation occurs in parallel across different geographic regions exhibiting similar ecological gradients (e.g., Jones et al. 2012). Therefore, for each differentiated CNV detected on on ...
... selection, confidence in the biological relevance of such differentiation can be increased by asking whether differentiation occurs in parallel across different geographic regions exhibiting similar ecological gradients (e.g., Jones et al. 2012). Therefore, for each differentiated CNV detected on on ...
SALSA MLPA probemix P018-F1 SHOX - MRC
... This P018-F1 SHOX probemix contains probes for each exon of the human SHOX gene, as well as a probe just before the SHOX promoter region. In addition, several probes are present detecting sequences in a region downstream of SHOX which has been implicated in regulation of SHOX transcription. Furtherm ...
... This P018-F1 SHOX probemix contains probes for each exon of the human SHOX gene, as well as a probe just before the SHOX promoter region. In addition, several probes are present detecting sequences in a region downstream of SHOX which has been implicated in regulation of SHOX transcription. Furtherm ...
GSEA - Bioinformatics Unit
... Enrichment statistic : To calculate the enrichment score, GSEA first walks down the ranked list of genes increasing a running-sum statistic when a gene is in the gene set and decreasing it when it is not. The enrichment score is the maximum deviation from zero encountered during that walk. This para ...
... Enrichment statistic : To calculate the enrichment score, GSEA first walks down the ranked list of genes increasing a running-sum statistic when a gene is in the gene set and decreasing it when it is not. The enrichment score is the maximum deviation from zero encountered during that walk. This para ...
Complete comparative genomic analysis of two field isolates of
... (v90/4, 15?0–27?1 kb; v90/2, 15?0–28?3 kb). In this 12?1 kb region (7?7 % of the genome), there are 261 of the 521 point mutations, accounting for 50 % of the total nucleotide changes. Of the 261 point mutations, 82 cause nonsynonymous changes and only the chitinase and orf27 genes do not have any a ...
... (v90/4, 15?0–27?1 kb; v90/2, 15?0–28?3 kb). In this 12?1 kb region (7?7 % of the genome), there are 261 of the 521 point mutations, accounting for 50 % of the total nucleotide changes. Of the 261 point mutations, 82 cause nonsynonymous changes and only the chitinase and orf27 genes do not have any a ...
ppt for
... 2) Olfactory receptors and miRNAs are lost at the same rate with which they are acquired. However, not a single cluster loss was observed for piRNA. ...
... 2) Olfactory receptors and miRNAs are lost at the same rate with which they are acquired. However, not a single cluster loss was observed for piRNA. ...
Affymetrix Software User Manuals
... Subject to the Affymetrix terms and conditions that govern your use of Affymetrix products, Affymetrix grants you a nonexclusive, non-transferable, non-sublicensable license to use this Affymetrix product only in accordance with the manual and written instructions provided by Affymetrix. You underst ...
... Subject to the Affymetrix terms and conditions that govern your use of Affymetrix products, Affymetrix grants you a nonexclusive, non-transferable, non-sublicensable license to use this Affymetrix product only in accordance with the manual and written instructions provided by Affymetrix. You underst ...
Deletions of NF1 gene and exons detected by multiplex ligation
... are small lesions, such as intraexonic deletions or insertions, splicing mutations, and nonsense or missense mutations.11 15–17 In these cases, the intrafamilial and interfamilial clinical variability of all symptoms is marked, precluding any prognosis regarding patient outcome even if the disease-c ...
... are small lesions, such as intraexonic deletions or insertions, splicing mutations, and nonsense or missense mutations.11 15–17 In these cases, the intrafamilial and interfamilial clinical variability of all symptoms is marked, precluding any prognosis regarding patient outcome even if the disease-c ...
Snorks Lab File
... In this simulation, you will examine the DNA sequence of a fictitious organism - the Snork. Snorks were discovered on the planet Dee Enae in a distant solar system. Snorks only have one chromosome with eight genes on it. Your job is to analyze the genes of its DNA and determine what traits the organ ...
... In this simulation, you will examine the DNA sequence of a fictitious organism - the Snork. Snorks were discovered on the planet Dee Enae in a distant solar system. Snorks only have one chromosome with eight genes on it. Your job is to analyze the genes of its DNA and determine what traits the organ ...
genomebiology.com
... introns that contain TEs in invertebrates D. melanogaster and C. elegans is 1.7% and 5.6%, respectively. These results indicate that only a very small portion of introns in invertebrates contain TEs (2 to 5%) compared to 20 to 40% of introns in non-mammalian vertebrates and approximately 60% in mamm ...
... introns that contain TEs in invertebrates D. melanogaster and C. elegans is 1.7% and 5.6%, respectively. These results indicate that only a very small portion of introns in invertebrates contain TEs (2 to 5%) compared to 20 to 40% of introns in non-mammalian vertebrates and approximately 60% in mamm ...
Inference of homologous recombination in bacteria using whole
... donor contributes only a small contiguous segment of DNA whereas the recipient contributes the rest of the genome. For a given sample of bacteria, it is thus possible to define its clonal genealogy [7] irrespective of how frequently recombination happened, by tracing back in time the ancestry of th ...
... donor contributes only a small contiguous segment of DNA whereas the recipient contributes the rest of the genome. For a given sample of bacteria, it is thus possible to define its clonal genealogy [7] irrespective of how frequently recombination happened, by tracing back in time the ancestry of th ...
An organism containing a normal chromosome complement and
... Other aneuploids (i.e. primary trisomics, tetrasomics, multiple trisomics, secondary trisomics, tertiary trisomics, compensating trisomics) ...
... Other aneuploids (i.e. primary trisomics, tetrasomics, multiple trisomics, secondary trisomics, tertiary trisomics, compensating trisomics) ...
Understanding Reads in RNA-Seq Analysis
... exonic, the read is labeled “exonic”, and the same goes for partially overlaps exon, intronic and intergenic. In the other words, exonic takes precedence over partially overlaps exon, partially overlaps exon takes precedence over intronic, and intronic takes precedence over intergenic. Exonic: A rea ...
... exonic, the read is labeled “exonic”, and the same goes for partially overlaps exon, intronic and intergenic. In the other words, exonic takes precedence over partially overlaps exon, partially overlaps exon takes precedence over intronic, and intronic takes precedence over intergenic. Exonic: A rea ...
Properties of Mitotic and Meiotic Recombination in the
... chromatid events have the phenotype 5-FOAR HygR GenR CanS. To determine the rates of these events shown in Table 1, for each strain, we allowed cells to form single colonies at 300 C. on rich growth medium (YPD). Each colony was suspended in water, and various dilutions were plated on SD complete, ...
... chromatid events have the phenotype 5-FOAR HygR GenR CanS. To determine the rates of these events shown in Table 1, for each strain, we allowed cells to form single colonies at 300 C. on rich growth medium (YPD). Each colony was suspended in water, and various dilutions were plated on SD complete, ...
Characterisation of interstitial duplications and triplications of
... showed that, in all cases, the duplications and triplications involved the PWACR and were not pseudogene expansions. Retrospective cytogenetic analysis in families 7 and 13 did not identify these duplications clearly. The size of the pericentromeric area of 15q varies greatly within the normal popul ...
... showed that, in all cases, the duplications and triplications involved the PWACR and were not pseudogene expansions. Retrospective cytogenetic analysis in families 7 and 13 did not identify these duplications clearly. The size of the pericentromeric area of 15q varies greatly within the normal popul ...
The Interplay of Temperature and Genotype on Patterns
... Temperature is one of the key environmental parameters, in particular for ectotherms such as Drosophila. A broad range of morphological, behavioral, and physiological responses to temperature has been described, but few studies attempted to compare the patterns of gene expression plasticity across t ...
... Temperature is one of the key environmental parameters, in particular for ectotherms such as Drosophila. A broad range of morphological, behavioral, and physiological responses to temperature has been described, but few studies attempted to compare the patterns of gene expression plasticity across t ...
Candidate gene scan for Single Nucleotide Polymorphisms involved
... signalling cascades of factors that control neural crest development, followed by a number of ...
... signalling cascades of factors that control neural crest development, followed by a number of ...
Identification of a Vinyl Reductase Gene for
... CIW8. We identified 38 plants that exhibited a recombination in this interval. New single nucleotide polymorphism markers were generated from the sequence information from the Monsant Arabidopsis polymorphism collection database, and we confirmed that the DVR gene is located on the region covered by ...
... CIW8. We identified 38 plants that exhibited a recombination in this interval. New single nucleotide polymorphism markers were generated from the sequence information from the Monsant Arabidopsis polymorphism collection database, and we confirmed that the DVR gene is located on the region covered by ...
Lecture 4
... • More than 200,000 expressed sequence tags available • Large scale transposon mutagenesis • Flybase: computer database and resource ...
... • More than 200,000 expressed sequence tags available • Large scale transposon mutagenesis • Flybase: computer database and resource ...
Unraveling the Genetic Mysteries of the Corneal Dystrophies
... peripheral nerves Corneal changes occur later in life Mutation localized to the gelsolin (GSN) gene on chromosome 9 (9q34) -Gelsolin modulates removal of actin in inflammation and injury; mutations result in the build-up of amyloid ...
... peripheral nerves Corneal changes occur later in life Mutation localized to the gelsolin (GSN) gene on chromosome 9 (9q34) -Gelsolin modulates removal of actin in inflammation and injury; mutations result in the build-up of amyloid ...
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... chromosome. The origin of the marker which contained chromosome 22 sequences was confirmed by FISH with the specific probe WCP22, showed strong/intense signal at the centromere region as a bi-satellite appearance- due to the isochromosome formation as also referred to `inverted duplication’ of the s ...
... chromosome. The origin of the marker which contained chromosome 22 sequences was confirmed by FISH with the specific probe WCP22, showed strong/intense signal at the centromere region as a bi-satellite appearance- due to the isochromosome formation as also referred to `inverted duplication’ of the s ...
Hox, ParaHox, ProtoHox: facts and guesses
... the origin of Bilaterians would have been linked only to the origin of a Central Hox gene. This model squares better with the close phylogenetic relationship of PG3 and Xlox. However, the argument still requires that two genes (PG3 and Xlox) were lost independently in the Cnidarian lineage. With a t ...
... the origin of Bilaterians would have been linked only to the origin of a Central Hox gene. This model squares better with the close phylogenetic relationship of PG3 and Xlox. However, the argument still requires that two genes (PG3 and Xlox) were lost independently in the Cnidarian lineage. With a t ...
Single-stranded heteroduplex intermediates in l Red homologous
... Background: The Red proteins of lambda phage mediate probably the simplest and most efficient homologous recombination reactions yet described. However the mechanism of dsDNA recombination remains undefined. Results: Here we show that the Red proteins can act via full length single stranded intermed ...
... Background: The Red proteins of lambda phage mediate probably the simplest and most efficient homologous recombination reactions yet described. However the mechanism of dsDNA recombination remains undefined. Results: Here we show that the Red proteins can act via full length single stranded intermed ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.