Importance of integrons in the diffusion of resistance
... structure and most of the elements belonging to this class are characterised by the presence of two conserved segments, the 5’-conserved segment (5’-CS) and 3’-conserved segment (3’-CS). The 5’-CS contains the intI gene, the attI site and the promoter, while the 3’-CS codes for the sul1 gene, confer ...
... structure and most of the elements belonging to this class are characterised by the presence of two conserved segments, the 5’-conserved segment (5’-CS) and 3’-conserved segment (3’-CS). The 5’-CS contains the intI gene, the attI site and the promoter, while the 3’-CS codes for the sul1 gene, confer ...
MiRNA_GO_Meeting_August2015
... Direct curation of the roles of miRNAs is expected to improve miRNA functional analysis that has so far relied on indirect analysis of the gene targets’ functions “We show that the most commonly used functional enrichment test is inappropriate for the analysis of sets of genes targeted by miRNAs.” B ...
... Direct curation of the roles of miRNAs is expected to improve miRNA functional analysis that has so far relied on indirect analysis of the gene targets’ functions “We show that the most commonly used functional enrichment test is inappropriate for the analysis of sets of genes targeted by miRNAs.” B ...
Identification of genes that are associated with DNA repeats in
... prokaryotic organisms, and their identification is increasingly facilitated by the availability of sequences of complete bacterial genomes. The length, sequence and position of these sequences in the genome are highly variable and often unique for a single strain (Lupski et al., 1996; Bachellier et ...
... prokaryotic organisms, and their identification is increasingly facilitated by the availability of sequences of complete bacterial genomes. The length, sequence and position of these sequences in the genome are highly variable and often unique for a single strain (Lupski et al., 1996; Bachellier et ...
A selfish origin for recombination
... 1996; Paques and Haber, 1999). Throughout this discussion I will refer to the physical process of interaction and exchange between two DNA molecules as crossing over, and recombination will mean a possible outcome of crossing over (producing recombinant chromosomes), the other possible outcome being ...
... 1996; Paques and Haber, 1999). Throughout this discussion I will refer to the physical process of interaction and exchange between two DNA molecules as crossing over, and recombination will mean a possible outcome of crossing over (producing recombinant chromosomes), the other possible outcome being ...
Trachemys scripta elegans Red-Eared Turtle ( Fc)
... which the secretory tail is not encoded by a separate exon but rather by the sequence immediately downstream of the CH2 exon (21). Because Igs play important roles in the adaptive immune system of all jawed vertebrates (1, 2), they have been extensively studied in various groups of animals, includin ...
... which the secretory tail is not encoded by a separate exon but rather by the sequence immediately downstream of the CH2 exon (21). Because Igs play important roles in the adaptive immune system of all jawed vertebrates (1, 2), they have been extensively studied in various groups of animals, includin ...
Estimating lethal allele frequencies in complex pedigrees via gene
... The GC method was proposed by ALLAIRE et al. (1982). This approach calculates the expected lethal allele frequency from known individual genotypes (carriers) among a set of relevant ancestors. Here we used a Fortran program written by LIDAUER and ESSL (1994) based on a concept developed by ALLAIRE e ...
... The GC method was proposed by ALLAIRE et al. (1982). This approach calculates the expected lethal allele frequency from known individual genotypes (carriers) among a set of relevant ancestors. Here we used a Fortran program written by LIDAUER and ESSL (1994) based on a concept developed by ALLAIRE e ...
Coexpression of Linked Genes in Mammalian
... coexpressed genes in several yeasts supports the adaptive model (Hurst et al. 2002), considering the recent discovery of long-range coregulation (;100 kb, covering ;30 genes) of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be hi ...
... coexpressed genes in several yeasts supports the adaptive model (Hurst et al. 2002), considering the recent discovery of long-range coregulation (;100 kb, covering ;30 genes) of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be hi ...
The SNP gff file is tab
... ID: the unique ID of a SNP. "rs***" is for SNP in dbSNP, “NOM1_” for novel SNPs. status: if the SNP is known or novel? "dbSNP" is for those in NCBI dbSNP dataset and "novel" for those not found in dbSNP ref: reference base of NCBI at the site allele: Diploid alleles of on this position support1: num ...
... ID: the unique ID of a SNP. "rs***" is for SNP in dbSNP, “NOM1_” for novel SNPs. status: if the SNP is known or novel? "dbSNP" is for those in NCBI dbSNP dataset and "novel" for those not found in dbSNP ref: reference base of NCBI at the site allele: Diploid alleles of on this position support1: num ...
important update on the status of curly calf syndrome
... conclusions reached today by Dr. Jon Beever of the University of Illinois. While those conclusions are serious and should be taken seriously by all of us, they arrive against a backdrop of significant scientific advancements in the field of molecular genetics. That science has evolved to the point w ...
... conclusions reached today by Dr. Jon Beever of the University of Illinois. While those conclusions are serious and should be taken seriously by all of us, they arrive against a backdrop of significant scientific advancements in the field of molecular genetics. That science has evolved to the point w ...
Divergent Evolution and Evolution by the Birth-and
... two heavy chains and two light chains. Both the heavy and light chains are composed of the variable region and the constant region (C). The variable region is responsible for antigen-binding, whereas the constant region is responsible for effector function. The heavy-chain variable region is encoded ...
... two heavy chains and two light chains. Both the heavy and light chains are composed of the variable region and the constant region (C). The variable region is responsible for antigen-binding, whereas the constant region is responsible for effector function. The heavy-chain variable region is encoded ...
Article The Pseudoautosomal Regions of the U/V Sex
... due to their being genetically linked to the nonrecombining, sex-determining region. This phenomenon is expected to occur in both diploid (XY, ZW) and haploid (UV) sexual systems, with slightly different consequences for UV sexual systems because of the absence of masking during the haploid phase (w ...
... due to their being genetically linked to the nonrecombining, sex-determining region. This phenomenon is expected to occur in both diploid (XY, ZW) and haploid (UV) sexual systems, with slightly different consequences for UV sexual systems because of the absence of masking during the haploid phase (w ...
The mitochondrial genome of the soybean cyst nematode
... tend to have slightly lower T-contents, with a range of 27% (Trichinella spiralis) to 44% (Agamermis sp.). A comparison with other pseudocoelomates (from the phyla Acanthocephala and Rotifera) indicates that they also have elevated Tcontents (Table 1). A high T-content appears to be a feature of pse ...
... tend to have slightly lower T-contents, with a range of 27% (Trichinella spiralis) to 44% (Agamermis sp.). A comparison with other pseudocoelomates (from the phyla Acanthocephala and Rotifera) indicates that they also have elevated Tcontents (Table 1). A high T-content appears to be a feature of pse ...
Molecular function - SGD-Wiki - Saccharomyces Genome Database
... • Highlighted rectangle in overview is region of genome displayed in detail panel • Region panel displays a portion of the genome surrounding the region of interest • Detail panel displays zoomed in view that corresponds to the overview selection rectangle ...
... • Highlighted rectangle in overview is region of genome displayed in detail panel • Region panel displays a portion of the genome surrounding the region of interest • Detail panel displays zoomed in view that corresponds to the overview selection rectangle ...
Daisy quorum drives for the genetic restoration of wild
... drive research. It's intended as a “living document” that begins by sharing key concepts, rationale, and experimental plans for viewing and comment by the community before any experiments begin. As data are gathered and analyses completed, it will be updated with new figures, and eventually will bec ...
... drive research. It's intended as a “living document” that begins by sharing key concepts, rationale, and experimental plans for viewing and comment by the community before any experiments begin. As data are gathered and analyses completed, it will be updated with new figures, and eventually will bec ...
An In Silico Investigation Into the Discovery of Novel Cis
... Several potential cis-regulatory motifs were identified in this investigation and one in particular that was common to both PAX7 and PAX3 and also to NF1, could have implications for the role of PAX7 in Alveolar Rhabdomyosarcoma and may be the cornerstone to more exciting, unique scientific investig ...
... Several potential cis-regulatory motifs were identified in this investigation and one in particular that was common to both PAX7 and PAX3 and also to NF1, could have implications for the role of PAX7 in Alveolar Rhabdomyosarcoma and may be the cornerstone to more exciting, unique scientific investig ...
Origin and evolution of Y chromosomes: Drosophila tales
... Before examining the results of Koerich et al. [9], it is worth mentioning a caveat. Ideally, the complete gene set of the Y chromosomes in the 12 species should be available before starting a comparative analysis, similar to the approach used (at least approximately) for analysing the euchromatic p ...
... Before examining the results of Koerich et al. [9], it is worth mentioning a caveat. Ideally, the complete gene set of the Y chromosomes in the 12 species should be available before starting a comparative analysis, similar to the approach used (at least approximately) for analysing the euchromatic p ...
Activation of Silent Genes by Transposons Tn5 and TnlO
... sought this characteristic phenotype among the mutations causing activation of the hisD gene. Each of the Hol+ revertants was used as a recipient in crosses with hisG point mutations located near the right end of the his-203 deletion (see previous section). These His+ recombinants, selected at 37", ...
... sought this characteristic phenotype among the mutations causing activation of the hisD gene. Each of the Hol+ revertants was used as a recipient in crosses with hisG point mutations located near the right end of the his-203 deletion (see previous section). These His+ recombinants, selected at 37", ...
Differential Gene Expression in the Siphonophore
... Both the Helicos and SOLiD sample preparation protocols are tag based – a single read is generated from a particular region of each sequenced mRNA molecule. In the case of Helicos Digital Gene Expression (DGE), the protocol is designed to generate a single read at the 59 end of each sequenced transc ...
... Both the Helicos and SOLiD sample preparation protocols are tag based – a single read is generated from a particular region of each sequenced mRNA molecule. In the case of Helicos Digital Gene Expression (DGE), the protocol is designed to generate a single read at the 59 end of each sequenced transc ...
Gene conversion rapidly generates major histocompatibility complex
... (McVean et al. 2002). This program uses a coalescentbased approach, and therefore while estimates of q ⁄ h > 1 are likely to be indicative of recombination, absolute estimates from data across populations need to be interpreted with caution. We developed a macro to quantify the level of shared polym ...
... (McVean et al. 2002). This program uses a coalescentbased approach, and therefore while estimates of q ⁄ h > 1 are likely to be indicative of recombination, absolute estimates from data across populations need to be interpreted with caution. We developed a macro to quantify the level of shared polym ...
Martina Šeruga Musić, Mladen Krajačić, Dijana Škorić
... Single-strand conformation polymorphism (SSCP) analysis is a broadly used relatively simple technique for detecting mutations. The aim of this work was to evaluate the applicability of SSCP analysis as a new tool for detection of phytoplasma molecular variability. Seventy phytoplasma isolates from g ...
... Single-strand conformation polymorphism (SSCP) analysis is a broadly used relatively simple technique for detecting mutations. The aim of this work was to evaluate the applicability of SSCP analysis as a new tool for detection of phytoplasma molecular variability. Seventy phytoplasma isolates from g ...
Recombination and clonal groupings within Helicobacter pylori from
... Akopyanz et al ., 1992a,b; Kansau et al ., 1996), and a comparison of the genomes of two strains has shown that 7% of the genes are specific to each strain (Alm et al ., 1999). However, bacteria isolated from the members of one family can be indistinguishable, or show only limited variation, which i ...
... Akopyanz et al ., 1992a,b; Kansau et al ., 1996), and a comparison of the genomes of two strains has shown that 7% of the genes are specific to each strain (Alm et al ., 1999). However, bacteria isolated from the members of one family can be indistinguishable, or show only limited variation, which i ...
The importance of alternative splicing in the drug discovery process
... Array RASL technology [20] and the in a significant apoptosis phenotype in PC-3 prostate cancer cells (adapted from [24]). splicing-specific microarrays used by Clark et al. [21], detect splice variants using probes spanning splice junctions, that is, boundaries results. If a complete shutdown of th ...
... Array RASL technology [20] and the in a significant apoptosis phenotype in PC-3 prostate cancer cells (adapted from [24]). splicing-specific microarrays used by Clark et al. [21], detect splice variants using probes spanning splice junctions, that is, boundaries results. If a complete shutdown of th ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.