draft - IC
... the genome shu e around, has been studied since shortly after the very advent of genetics [1, 2, 3]. With the increased availability of whole genome sequences, gene order data have been used to estimate the evolutionary distance between present-day genomes and to reconstruct the gene order of ancest ...
... the genome shu e around, has been studied since shortly after the very advent of genetics [1, 2, 3]. With the increased availability of whole genome sequences, gene order data have been used to estimate the evolutionary distance between present-day genomes and to reconstruct the gene order of ancest ...
SNP Analysis (GAW15 data)
... Chromosome 6: known strong genetic factors conforms well to the expected frequency of Hardy-Weinberg disequilibrium with this large set of markers. ...
... Chromosome 6: known strong genetic factors conforms well to the expected frequency of Hardy-Weinberg disequilibrium with this large set of markers. ...
genomic flux: genome evolution by gene loss and
... The evidence for gene acquisition in many organisms has been detailed elsewhere (64). In bacteria, horizontally transferred genes frequently confer phenotypes that are characteristic of particular taxonomic groups. Bacterial taxonomists assign a new isolate to a particular species by scoring possess ...
... The evidence for gene acquisition in many organisms has been detailed elsewhere (64). In bacteria, horizontally transferred genes frequently confer phenotypes that are characteristic of particular taxonomic groups. Bacterial taxonomists assign a new isolate to a particular species by scoring possess ...
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... assembly. We also found that more mRNAs had higher percentage matches in Cel2 than in MGSCv3 (that is, > 97%). As a further test, we especially investigated how well long mRNAs can be matched to each assembly. The 10 longest mRNA sequences are all matched well with both assemblies, except for the pi ...
... assembly. We also found that more mRNAs had higher percentage matches in Cel2 than in MGSCv3 (that is, > 97%). As a further test, we especially investigated how well long mRNAs can be matched to each assembly. The 10 longest mRNA sequences are all matched well with both assemblies, except for the pi ...
Get PDF - Wiley Online Library
... 2009). We recently suggested that some aneuploid CNVs may be selected to balance the effects of mutations, epigenetic silencing, and other gene losses acquired during the continuous division of chromosomally unstable cancer cells (Bazeley et al., 2011). We now show evidence for increased mRNA levels ...
... 2009). We recently suggested that some aneuploid CNVs may be selected to balance the effects of mutations, epigenetic silencing, and other gene losses acquired during the continuous division of chromosomally unstable cancer cells (Bazeley et al., 2011). We now show evidence for increased mRNA levels ...
Chpt9_Transposition.doc
... viruses move between individuals, at least some transposable elements can move between genomes (between individuals) as well as within an individual’s genome. Given their prevalence in genomes, the function (if any) of transposable elements has been much discussed but is little understood. It is not ...
... viruses move between individuals, at least some transposable elements can move between genomes (between individuals) as well as within an individual’s genome. Given their prevalence in genomes, the function (if any) of transposable elements has been much discussed but is little understood. It is not ...
—1— User Guide © Copyright 2009 Robert C. Edgar, all rights
... (inter) once for the entire genome, then the intra-chromosome simulator (intra) once for each chromosome. This process is called a cycle. The output from one cycle can be used as input to another cycle. It is generally better to run many short cycles rather than one or a few long cycles as longer cy ...
... (inter) once for the entire genome, then the intra-chromosome simulator (intra) once for each chromosome. This process is called a cycle. The output from one cycle can be used as input to another cycle. It is generally better to run many short cycles rather than one or a few long cycles as longer cy ...
Getting Started
... is used for a diverse range of species structured to be queried at different levels, eg: find all the chicken gene products in the genome that are involved in signal transduction zoom in on all the receptor tyrosine kinases human readable GO function has a digital tag to allow computationa ...
... is used for a diverse range of species structured to be queried at different levels, eg: find all the chicken gene products in the genome that are involved in signal transduction zoom in on all the receptor tyrosine kinases human readable GO function has a digital tag to allow computationa ...
Table S1.
... Only genes are taken into account that overlap by at least one base pair with window. Attributes are then calculated at exon level for each exon that fulfils the patch overlap definition (overlap >25% of exon length or >10% of window size): _elen = total length of exonic DNA with window, standardize ...
... Only genes are taken into account that overlap by at least one base pair with window. Attributes are then calculated at exon level for each exon that fulfils the patch overlap definition (overlap >25% of exon length or >10% of window size): _elen = total length of exonic DNA with window, standardize ...
The dystrophin / utrophin homologues in Drosophila and in sea urchin
... further downstream in the huge DMD gene regulate the expression of smaller products. Dp71, a 70.8 kDa protein, consists of only the cysteine-rich and C-terminal domains of dystrophin (Bar et al., 1990; Lederfein et al., 1992). It is the most abundant non-muscle product of the DMD gene. The highest l ...
... further downstream in the huge DMD gene regulate the expression of smaller products. Dp71, a 70.8 kDa protein, consists of only the cysteine-rich and C-terminal domains of dystrophin (Bar et al., 1990; Lederfein et al., 1992). It is the most abundant non-muscle product of the DMD gene. The highest l ...
New methods for tightly regulated gene expression and
... 1997); however, this approach often introduces experimental artifacts owing to the higher plasmid copy number. For example, we have found that transformation can be difficult, or impossible, with plasmids carrying genes encoding membrane proteins or highly expressed reporter gene fusions. Further, p ...
... 1997); however, this approach often introduces experimental artifacts owing to the higher plasmid copy number. For example, we have found that transformation can be difficult, or impossible, with plasmids carrying genes encoding membrane proteins or highly expressed reporter gene fusions. Further, p ...
Integrated genome sequence and linkage map of physic nut
... 812 Pingzhi Wu et al. of the connected contigs was generally correct. Third, we used the LASTZ program to perform whole genome scaffoldto-scaffold alignment of our physic nut genome assembly (632 scaffolds were covered) with that presented by Hirakawa et al. (2012). The two genomes exhibited good c ...
... 812 Pingzhi Wu et al. of the connected contigs was generally correct. Third, we used the LASTZ program to perform whole genome scaffoldto-scaffold alignment of our physic nut genome assembly (632 scaffolds were covered) with that presented by Hirakawa et al. (2012). The two genomes exhibited good c ...
gene duplication in the evolution of sexual dimorphism
... whole-body hybridizations. The detection of sex-bias depends on the statistical approach and power of a given experimental design, which may partly explain differences among studies in the number of sex-biased genes identified. Furthermore, because evolutionarily recent gene duplicates are expected ...
... whole-body hybridizations. The detection of sex-bias depends on the statistical approach and power of a given experimental design, which may partly explain differences among studies in the number of sex-biased genes identified. Furthermore, because evolutionarily recent gene duplicates are expected ...
Interfering RNA
... • showing of antisense targets across mRNA may be sufficient, but not all antisense targets are open to siRNA • intron targets may not be active for siRNA but may be for antisense – identify all elements claimed and their support in the description – identify species explicitly or implicitly disclos ...
... • showing of antisense targets across mRNA may be sufficient, but not all antisense targets are open to siRNA • intron targets may not be active for siRNA but may be for antisense – identify all elements claimed and their support in the description – identify species explicitly or implicitly disclos ...
BMC Genomics 10
... SNP-based genetic variation is found with high density throughout the genome. Efficient technologies have been developed, which allow for highly parallel and cost efficient genotyping, SNPs have therefore become the markers of choice for genetic mapping. This makes SNP maps highly suitable for assoc ...
... SNP-based genetic variation is found with high density throughout the genome. Efficient technologies have been developed, which allow for highly parallel and cost efficient genotyping, SNPs have therefore become the markers of choice for genetic mapping. This makes SNP maps highly suitable for assoc ...
A Case Study of Leopard Appaloosa Alpacas in one
... Ambersun herd showed them to have been sired by five separate males. If the gene is so rare, it seems beyond coincidence that five different males would be carrying the same gene. The results, therefore, would tend to support the earlier assertion based on research with horses as (Wilpedia, 2009) th ...
... Ambersun herd showed them to have been sired by five separate males. If the gene is so rare, it seems beyond coincidence that five different males would be carrying the same gene. The results, therefore, would tend to support the earlier assertion based on research with horses as (Wilpedia, 2009) th ...
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... been excluded. Thus the relationship between transposable elements and their hosts may be as much symbiotic as parasitic. Resolving these issues is an interesting challenge for future research. Discovery of transposable elements as controlling elements in maize The discovery of transposable elements ...
... been excluded. Thus the relationship between transposable elements and their hosts may be as much symbiotic as parasitic. Resolving these issues is an interesting challenge for future research. Discovery of transposable elements as controlling elements in maize The discovery of transposable elements ...
... Saccharomyces kudriavzevii was described. These strains exhibit physiological properties of potential biotechnological interest. A preliminary characterization of these hybrids showed a trend to reduce the S. kudriavzevii fraction of the hybrid genome. We characterized the genomic constitution of se ...
Reference genome sequence of the model plant Setaria
... A genetic map for Setaria A cross between S. italica inbred B100 and S. viridis accession A10 was performed in 1997, and an F2 generation of this cross was used to generate the first genetic map of Setaria italica/viridis11,24. We used 247 progeny of this cross to construct a recombinant inbred line ...
... A genetic map for Setaria A cross between S. italica inbred B100 and S. viridis accession A10 was performed in 1997, and an F2 generation of this cross was used to generate the first genetic map of Setaria italica/viridis11,24. We used 247 progeny of this cross to construct a recombinant inbred line ...
Article Old but Not (So) Degenerated—Slow
... genes hemizygous in females, we estimate that about one-third of the Z chromosome does not recombine with the W chromosome in female meiosis. Pairwise dN/dS between gametologs decreased with age, suggesting strong evolutionary constraint in old gametologs. Lineage-specific dN/dS was consistently hig ...
... genes hemizygous in females, we estimate that about one-third of the Z chromosome does not recombine with the W chromosome in female meiosis. Pairwise dN/dS between gametologs decreased with age, suggesting strong evolutionary constraint in old gametologs. Lineage-specific dN/dS was consistently hig ...
Role for CCG-trinucleotide repeats in the pathogenesis of chronic
... Figure 1. Localization of the minimal region of deletion and patients’ breakpoints on the 40-Mb 11q contig. The locations of the trinucleotide repeats and the FRA11B fragile site are indicated by bold type. The various genes and D11S markers in the region are also indicated at the top of the figure, ...
... Figure 1. Localization of the minimal region of deletion and patients’ breakpoints on the 40-Mb 11q contig. The locations of the trinucleotide repeats and the FRA11B fragile site are indicated by bold type. The various genes and D11S markers in the region are also indicated at the top of the figure, ...
IGA 8/e Chapter 4
... 15. Point refers to locus. The usage does not imply linkage, but rather a testing for possible linkage. A four-point testcross would look like the following: a/+ · b/+ · c/+ · d/+ a/a · b/b · c/c · d/d. 16. A recombinant refers to an individual who has alleles inherited from two different grandpar ...
... 15. Point refers to locus. The usage does not imply linkage, but rather a testing for possible linkage. A four-point testcross would look like the following: a/+ · b/+ · c/+ · d/+ a/a · b/b · c/c · d/d. 16. A recombinant refers to an individual who has alleles inherited from two different grandpar ...
The nucleotide sequence of Saccharomyces cerevisiae
... is a single ORF. The putative pseudogene on the right arm of the chromosome is highly similar to a single ORF on chromosome XIII. The centromere11 of chromosome IX is located towards the right end of the chromosome between bases 355,627 and 355,744. Sequencing has revealed the definitive chromosomal ...
... is a single ORF. The putative pseudogene on the right arm of the chromosome is highly similar to a single ORF on chromosome XIII. The centromere11 of chromosome IX is located towards the right end of the chromosome between bases 355,627 and 355,744. Sequencing has revealed the definitive chromosomal ...
1 Single molecule sequencing of THCA synthase reveals
... and Sirikantaramas work, van Bakel et al. reported a gene of unknown function (AAE3) that was differentially replicated in drug versus fiber type cannabis(van Bakel et al., ...
... and Sirikantaramas work, van Bakel et al. reported a gene of unknown function (AAE3) that was differentially replicated in drug versus fiber type cannabis(van Bakel et al., ...
The Jumping SHOX Gene—Crossover in the Pseudoautosomal
... of sex. Here we describe three families in which an abnormality in PAR1 segregates from one sex chromosome to the other in the next generation. PAR1 is highly homologous and is therefore necessary for X-Y chromosome-pairing during male meiosis (11). As with autosomes, it undergoes one obligatory cro ...
... of sex. Here we describe three families in which an abnormality in PAR1 segregates from one sex chromosome to the other in the next generation. PAR1 is highly homologous and is therefore necessary for X-Y chromosome-pairing during male meiosis (11). As with autosomes, it undergoes one obligatory cro ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.