Polymorphism of FecB Gene in Nine Sheep Breeds or Strains and
... other factors. Muslant et al. [1] and Wilson et al. [3] reported that FecB is a major gene inherited as a single autosomal locus, which regulates ovulation rate of Booroola sheep. Using DNA testing we also found that the FecB gene followed Mendelian segregation patterns in Hu sheep and crossbreds. D ...
... other factors. Muslant et al. [1] and Wilson et al. [3] reported that FecB is a major gene inherited as a single autosomal locus, which regulates ovulation rate of Booroola sheep. Using DNA testing we also found that the FecB gene followed Mendelian segregation patterns in Hu sheep and crossbreds. D ...
Insights into three whole-genome duplications gleaned
... caudatum and the P. aurelia species, a substantial degree of local synteny remains (Figure 2). We were able to align 5,781 P. caudatum genes with all 12 of their syntenic aurelia orthologs (when present), which includes 10,907 P. biaurelia, 10,970 P. tetraurelia, and 10,024 P. sexaurelia genes (File ...
... caudatum and the P. aurelia species, a substantial degree of local synteny remains (Figure 2). We were able to align 5,781 P. caudatum genes with all 12 of their syntenic aurelia orthologs (when present), which includes 10,907 P. biaurelia, 10,970 P. tetraurelia, and 10,024 P. sexaurelia genes (File ...
Handbook on SMA genetics_final_051209
... intragenic SMN1 point mutations. Exonic regions must be individually amplified; therefore, sequence analysis does not detect exonic deletions or duplications. ...
... intragenic SMN1 point mutations. Exonic regions must be individually amplified; therefore, sequence analysis does not detect exonic deletions or duplications. ...
Current Microbiology
... Abstract. The bidirectional, NAD1-dependent hydrogenase from cyanobacteria is encoded by the structural genes hoxFUYH, which have been found to be clustered, though interspersed with different open reading frames (ORFs), in the heterocystous, N2-fixing Anabaena variabilis and in the unicellular Syne ...
... Abstract. The bidirectional, NAD1-dependent hydrogenase from cyanobacteria is encoded by the structural genes hoxFUYH, which have been found to be clustered, though interspersed with different open reading frames (ORFs), in the heterocystous, N2-fixing Anabaena variabilis and in the unicellular Syne ...
Sequence of the Tribolium castaneum Homeotic Complex
... are dispersed randomly throughout the contig, are predominantly A, T, or A/T rich and comprise 3.25% of the total sequence. Polymorphisms in Tribolium DNA: The sequences of Bmxp1 and 35E10 match perfectly in the 4.2 kb by which they overlap. In contrast, we found several single nucleotide polymorphi ...
... are dispersed randomly throughout the contig, are predominantly A, T, or A/T rich and comprise 3.25% of the total sequence. Polymorphisms in Tribolium DNA: The sequences of Bmxp1 and 35E10 match perfectly in the 4.2 kb by which they overlap. In contrast, we found several single nucleotide polymorphi ...
Patterns of prokaryotic lateral gene transfers affecting
... Full list of author information is available at the end of the article ...
... Full list of author information is available at the end of the article ...
Analysis of Genetic Toggle Switch Systems Encoded on Plasmids
... exclusive switch there is an overlap between the two promoter sites, so they cannot be occupied at the same time. The studies in Refs. [27] focused on the case in which the switch system is encoded on the chromosome, namely, each gene and its promoter site appears in a single copy. In addition, coop ...
... exclusive switch there is an overlap between the two promoter sites, so they cannot be occupied at the same time. The studies in Refs. [27] focused on the case in which the switch system is encoded on the chromosome, namely, each gene and its promoter site appears in a single copy. In addition, coop ...
Get
... proteins structure and function • Alter base sequence - MAY change protein GOOD, BAD or INDIFFERENT CRC for Discovery of Genes for Common Human Diseases (the gene CRC) ...
... proteins structure and function • Alter base sequence - MAY change protein GOOD, BAD or INDIFFERENT CRC for Discovery of Genes for Common Human Diseases (the gene CRC) ...
Patient with syndromic cleft lip-palate, mosaic karyotype and
... Objective. Cleft lip with or without cleft palate (CLP) is a common congenital abnormality involving genetic and non-genetic factors in its etiology. Although many studies have been made to find the genetic pattern of this malformation, there is still no precise answer. There have been suggested sev ...
... Objective. Cleft lip with or without cleft palate (CLP) is a common congenital abnormality involving genetic and non-genetic factors in its etiology. Although many studies have been made to find the genetic pattern of this malformation, there is still no precise answer. There have been suggested sev ...
Genome Projector: zoomable genome map with multiple views
... green for the complementary strand. rRNAs are represented by pink and orange stripes, depending on the strand. rRNAs tend to strongly prefer the leading strand, and in some genomes, many rRNAs are located close to the replication origin. The copy numbers of tRNAs and rRNAs have been suggested to cor ...
... green for the complementary strand. rRNAs are represented by pink and orange stripes, depending on the strand. rRNAs tend to strongly prefer the leading strand, and in some genomes, many rRNAs are located close to the replication origin. The copy numbers of tRNAs and rRNAs have been suggested to cor ...
Patterns of Segmental Duplication in the Human Genome
... one segment. The alignment end was extended by a dynamic programming for up to 5 kb outward from both ends of the alignment, while maintaining the requirement 90% sequence similarity during the extension process. Noting that some regions showed a higher density of duplication than others, we exami ...
... one segment. The alignment end was extended by a dynamic programming for up to 5 kb outward from both ends of the alignment, while maintaining the requirement 90% sequence similarity during the extension process. Noting that some regions showed a higher density of duplication than others, we exami ...
Scientist finds the gene that determines major sensitivity to bitter taste
... Using information from a variety of populations and individuals with differences in their ability to sense PTC, these investigators identified the small region on 7q that shows strong linkage disequilibrium between SNP markers (single nucleotide polymorphisms), and PTC sensitivity in unrelated subj ...
... Using information from a variety of populations and individuals with differences in their ability to sense PTC, these investigators identified the small region on 7q that shows strong linkage disequilibrium between SNP markers (single nucleotide polymorphisms), and PTC sensitivity in unrelated subj ...
Evolution at the Subgene Level: Domain Rearrangements in
... in many ways. For example, gene duplication has long been identified as a major mechanism for generating new genes and functions (Ohno 1970; Lynch and Conery 2000; Long et al. 2003), whereas gene loss plays a similarly important role in shaping genomic content (Hahn, Demuth, et al. 2007; Niimura and ...
... in many ways. For example, gene duplication has long been identified as a major mechanism for generating new genes and functions (Ohno 1970; Lynch and Conery 2000; Long et al. 2003), whereas gene loss plays a similarly important role in shaping genomic content (Hahn, Demuth, et al. 2007; Niimura and ...
Genetic association between the PRKCH gene encoding protein
... Consortium on Rheumatoid Arthritis Families focused on Europeans (7,8), Shiozawa et al focused on Japanese (9), the North American Rheumatoid Arthritis Consortium focused on Caucasians living in the US (10,11), and the Arthritis Research Campaign: UK National Repository of Multicase RA Families focu ...
... Consortium on Rheumatoid Arthritis Families focused on Europeans (7,8), Shiozawa et al focused on Japanese (9), the North American Rheumatoid Arthritis Consortium focused on Caucasians living in the US (10,11), and the Arthritis Research Campaign: UK National Repository of Multicase RA Families focu ...
Robust Prediction of Expression Differences among Human
... the remaining unseen individuals [24]. This work also integrated genomic features of SNPs, using them as priors in a regularized linear model, and found SNPs located in certain regions of the gene to be more predictive of gene expression variation. However, in addition to the SNP information, this w ...
... the remaining unseen individuals [24]. This work also integrated genomic features of SNPs, using them as priors in a regularized linear model, and found SNPs located in certain regions of the gene to be more predictive of gene expression variation. However, in addition to the SNP information, this w ...
High-resolution haplotype structure in the human genome
... using haplotypes generated by the transmission disequilibrium test (TDT) implementation in Genehunter 2.0 (ref. 22), followed by use of an EM-type algorithm23,24, to include the minority of chromosomes that had one or more markers with ambiguous phase (that is, where both parents and offspring were ...
... using haplotypes generated by the transmission disequilibrium test (TDT) implementation in Genehunter 2.0 (ref. 22), followed by use of an EM-type algorithm23,24, to include the minority of chromosomes that had one or more markers with ambiguous phase (that is, where both parents and offspring were ...
Human karyotype
... Stabilize chromosome movement during cell division Site where chromosome attaches to spindle Acentric chromosome: Chromosome that lacks a centromere; segregates abnormally in mitosis or meiosis. Dicentric chromosome: Chromosome with two centromeres; unstable, usually breaks during cell division. ...
... Stabilize chromosome movement during cell division Site where chromosome attaches to spindle Acentric chromosome: Chromosome that lacks a centromere; segregates abnormally in mitosis or meiosis. Dicentric chromosome: Chromosome with two centromeres; unstable, usually breaks during cell division. ...
Concept_Paper
... Genes are compact in genomic space. Introns are few, small and are not spliced in alternative forms. They comprise at most about a third of the transcribed DNA [from ref. 37]. This compactness is also evident in the related ciliate Paramecium, in which an 8- ...
... Genes are compact in genomic space. Introns are few, small and are not spliced in alternative forms. They comprise at most about a third of the transcribed DNA [from ref. 37]. This compactness is also evident in the related ciliate Paramecium, in which an 8- ...
Journal of Biotechnology
... iturin A, C, D and E, bacillomycin F and L, bacillopeptin and mycosubtilin (Moyne et al., 2004). Iturins contain one -amino fatty acid and seven ␣-amino acids with a d-tyrosine as the second amino acid and two additional d-amino acids at positions 3 and 6. These agents exhibit strong antifungal and ...
... iturin A, C, D and E, bacillomycin F and L, bacillopeptin and mycosubtilin (Moyne et al., 2004). Iturins contain one -amino fatty acid and seven ␣-amino acids with a d-tyrosine as the second amino acid and two additional d-amino acids at positions 3 and 6. These agents exhibit strong antifungal and ...
Statistical analysis of simple repeats in the human genome
... of runs of amino acids, and retroviruses inserted in the genome. For example, the human genome contains more than 50 chemokine receptor genes which have high sequence similarity [2] and almost one thousands olfactory receptor genes and pseudogenes [3]. Short repetitive DNA sequences may be categoriz ...
... of runs of amino acids, and retroviruses inserted in the genome. For example, the human genome contains more than 50 chemokine receptor genes which have high sequence similarity [2] and almost one thousands olfactory receptor genes and pseudogenes [3]. Short repetitive DNA sequences may be categoriz ...
draft - IC
... the genome shu e around, has been studied since shortly after the very advent of genetics [1, 2, 3]. With the increased availability of whole genome sequences, gene order data have been used to estimate the evolutionary distance between present-day genomes and to reconstruct the gene order of ancest ...
... the genome shu e around, has been studied since shortly after the very advent of genetics [1, 2, 3]. With the increased availability of whole genome sequences, gene order data have been used to estimate the evolutionary distance between present-day genomes and to reconstruct the gene order of ancest ...
Technical standards and guidelines for spinal muscular atrophy testing
... SMN2 gene produces predominantly an alternatively spliced transcript (exon 7 deleted) encoding a protein (SMN⌬7) that does not oligomerize efficiently and is unstable.26,27 The inclusion of exon 7 in SMN1 transcripts and exclusion of this exon in SMN2 transcripts are caused by the single nucleotide ...
... SMN2 gene produces predominantly an alternatively spliced transcript (exon 7 deleted) encoding a protein (SMN⌬7) that does not oligomerize efficiently and is unstable.26,27 The inclusion of exon 7 in SMN1 transcripts and exclusion of this exon in SMN2 transcripts are caused by the single nucleotide ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.