
Effective Gene Selection Method Using Bayesian Discriminant
... The computational complexity of the SFS is O(M2), where M is the number of genes. A microarray gene expression dataset generally contains information of thousands or ten thousands genes. Clearly, directly handling a huge gene set may cost an unbearable computational burden. Given by the fact that mo ...
... The computational complexity of the SFS is O(M2), where M is the number of genes. A microarray gene expression dataset generally contains information of thousands or ten thousands genes. Clearly, directly handling a huge gene set may cost an unbearable computational burden. Given by the fact that mo ...
summary_Stickleback_Seg_Dup
... only affect a small proportion of NR space. These sequence intervals should also be detected by WSSD if they are the repeats. However, I did not take them out from Alldup(which is a merge of WGAC and WSSD) yet, because many of them has high frequency hit on chrUn. At this stage we do not know if the ...
... only affect a small proportion of NR space. These sequence intervals should also be detected by WSSD if they are the repeats. However, I did not take them out from Alldup(which is a merge of WGAC and WSSD) yet, because many of them has high frequency hit on chrUn. At this stage we do not know if the ...
Dow, Graham: The limitation of genome wide association studies
... formation leaves an unquenchable thirst to uncover more powerful genetic components. The source of such critical players in disease might be the exact variants that genome wide association studies overlook – rare variants. Rare variants that exist in the population at frequencies bel ...
... formation leaves an unquenchable thirst to uncover more powerful genetic components. The source of such critical players in disease might be the exact variants that genome wide association studies overlook – rare variants. Rare variants that exist in the population at frequencies bel ...
General background text Pharmacogenetics
... There is also great variation in metabolic capacity within the IM and EM groups. The PM phenotype particularly leads to a strong increase in cellular concentration of the active metabolites (thioguanine nucleotides), which almost always leads to serious side effects such as bone marrow depression at ...
... There is also great variation in metabolic capacity within the IM and EM groups. The PM phenotype particularly leads to a strong increase in cellular concentration of the active metabolites (thioguanine nucleotides), which almost always leads to serious side effects such as bone marrow depression at ...
12859_2006_1447_MOESM4_ESM
... The Extended Alternatively Spliced EST Database (EASED; http://eased.bioinf.mdcberlin.de/ ) is an online compendium of alternative splicing for several organisms including human [7]. Splice forms are defined by alignment of ESTs with mRNA using ...
... The Extended Alternatively Spliced EST Database (EASED; http://eased.bioinf.mdcberlin.de/ ) is an online compendium of alternative splicing for several organisms including human [7]. Splice forms are defined by alignment of ESTs with mRNA using ...
Eugenic Evolution Utilizing a Domain Model / (c)
... somes via recombination of existing chromosomes, with a component of mutation. The information inherited by a single new chromosome is derived from only a small percentage of the total information present in the population. Recently, evolutionary algorithm research has progressed towards increasingl ...
... somes via recombination of existing chromosomes, with a component of mutation. The information inherited by a single new chromosome is derived from only a small percentage of the total information present in the population. Recently, evolutionary algorithm research has progressed towards increasingl ...
Dry bean collection from around the world helps
... domesticated species. Getting the key gene sequence from a wild bean into a great northern bean with the required seed size would take five years using regular hybridization, working year-round in a greenhouse. First the wild bean is crossed with a cultivated bean, then it is “back crossed” for eigh ...
... domesticated species. Getting the key gene sequence from a wild bean into a great northern bean with the required seed size would take five years using regular hybridization, working year-round in a greenhouse. First the wild bean is crossed with a cultivated bean, then it is “back crossed” for eigh ...
Warren, ST and Nelson, DL: Trinucleotide repeat expansions in neurological disease. Current Opinion in Neurobiology 3:752-759 (1993).
... individuals. It is a neurodegenerative disease characterized by choreiform movement and progressive intellectual deterioration associated with atrophy of the caudate and putamen. Age-of-onset is usually in middle age (35-50 years), though juvenile cases, which are typically more severe, are occasion ...
... individuals. It is a neurodegenerative disease characterized by choreiform movement and progressive intellectual deterioration associated with atrophy of the caudate and putamen. Age-of-onset is usually in middle age (35-50 years), though juvenile cases, which are typically more severe, are occasion ...
[ 19] Saccharomyces Genome Database - SGD-Wiki
... Registry form (http:l/genome-www4.stanford.edu/cgi-binlSGDIregistry/geneRegistry). In 1994 Robert Mortimer transferred the task of maintaining the nomenclature orS. cerevisiae genes, the Gene Name Registry, to SGD. Yeast researchers can reserve a gene name or register a published gene name by submit ...
... Registry form (http:l/genome-www4.stanford.edu/cgi-binlSGDIregistry/geneRegistry). In 1994 Robert Mortimer transferred the task of maintaining the nomenclature orS. cerevisiae genes, the Gene Name Registry, to SGD. Yeast researchers can reserve a gene name or register a published gene name by submit ...
General Introduction
... starch molecules. The same enzyme also influences the expression of other enzymes (coded by other genes) that are also involved with starch production. The other allele, w, makes an alternative form of enzyme that is less efficient in doing early embryonic branching of starch. The result is that the ...
... starch molecules. The same enzyme also influences the expression of other enzymes (coded by other genes) that are also involved with starch production. The other allele, w, makes an alternative form of enzyme that is less efficient in doing early embryonic branching of starch. The result is that the ...
Saccharomyces Genome Database.
... Registry form (http:l/genome-www4.stanford.edu/cgi-binlSGDIregistry/geneRegistry). In 1994 Robert Mortimer transferred the task of maintaining the nomenclature orS. cerevisiae genes, the Gene Name Registry, to SGD. Yeast researchers can reserve a gene name or register a published gene name by submit ...
... Registry form (http:l/genome-www4.stanford.edu/cgi-binlSGDIregistry/geneRegistry). In 1994 Robert Mortimer transferred the task of maintaining the nomenclature orS. cerevisiae genes, the Gene Name Registry, to SGD. Yeast researchers can reserve a gene name or register a published gene name by submit ...
Charcot Marie Tooth Disease Essay Research Paper
... The gene Cx32 explains the mixed CMTI/CMTII and CMTX variations of CMT. Cx32 mutations are the second most prevalent mutation found in CMT-I. Over 150 mutations have been described, including deletions, missense, nonsense, and frameshift mutations. Unlike PMP22 and mpz, the range of clinical severi ...
... The gene Cx32 explains the mixed CMTI/CMTII and CMTX variations of CMT. Cx32 mutations are the second most prevalent mutation found in CMT-I. Over 150 mutations have been described, including deletions, missense, nonsense, and frameshift mutations. Unlike PMP22 and mpz, the range of clinical severi ...
Comparative Genetic Mapping Revealed Powdery Mildew
... Molecular markers are powerful tools to identify parts of DNA that are located near a gene of interest. Restriction fragment length polymorphisms (RFLP), simple sequence repeats (SSR), random amplified polymorphisms DNA (RAPD), sequence tagged site (STS) and amplified fragment length polymorphisms ( ...
... Molecular markers are powerful tools to identify parts of DNA that are located near a gene of interest. Restriction fragment length polymorphisms (RFLP), simple sequence repeats (SSR), random amplified polymorphisms DNA (RAPD), sequence tagged site (STS) and amplified fragment length polymorphisms ( ...
Module 8: Horizontal Gene Transfer
... 7. After clicking on the Image in PNG format (bitmap) in Figure 8.14 has been clicked, an unrooted phylogenetic tree similar to the one shown in Figure 8.15 will appear. A concise review of the interpretation of figure 8.14 can be found at: http://epidemic.bio.ed.ac.uk/how_to_read_a_phylogeny. A sum ...
... 7. After clicking on the Image in PNG format (bitmap) in Figure 8.14 has been clicked, an unrooted phylogenetic tree similar to the one shown in Figure 8.15 will appear. A concise review of the interpretation of figure 8.14 can be found at: http://epidemic.bio.ed.ac.uk/how_to_read_a_phylogeny. A sum ...
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
... another ORF. All have a low codon adaptation index (CAI) of not greater than 0.18, are short (with an average length of 132 codons), and have no known homology with other proteins or are associated with no known phenotype. For four of these ORFs in two pairs (YPL034c and YPL035c, and YPR038w and YPR ...
... another ORF. All have a low codon adaptation index (CAI) of not greater than 0.18, are short (with an average length of 132 codons), and have no known homology with other proteins or are associated with no known phenotype. For four of these ORFs in two pairs (YPL034c and YPL035c, and YPR038w and YPR ...
BioinformaIcs Journal Club
... symbionts whose distribuBon is strongly correlated with plant specializaBon of their hosts, and it has been posited that some of these symbionts could have a role in plant adaptaBon, although clear evide ...
... symbionts whose distribuBon is strongly correlated with plant specializaBon of their hosts, and it has been posited that some of these symbionts could have a role in plant adaptaBon, although clear evide ...
emboj7601802-sup
... spectinomycin resistance cassette downstream of the atpB gene, in a region that belongs to the inverted repeat. Gene conversion between the two copies of the inverted repeat could thus lead to the duplication of the resistance cassette. The new copy of the cassette, not linked to the truncated atpB ...
... spectinomycin resistance cassette downstream of the atpB gene, in a region that belongs to the inverted repeat. Gene conversion between the two copies of the inverted repeat could thus lead to the duplication of the resistance cassette. The new copy of the cassette, not linked to the truncated atpB ...
The HapMap Project Tutorial
... For phased haplotypes, alleles colored yellow and blue Phasing was done in two steps: ...
... For phased haplotypes, alleles colored yellow and blue Phasing was done in two steps: ...
Fine Mapping of Two Wheat Powdery Mildew Resistance Genes
... cluster. Mlm2033 and Mlm80 from einkorn wheat (T. monococcum L.) were two of the R genes belonging to this cluster. This study was initiated to fine map these two genes toward map-based cloning. Comparative genomics study showed that macrocolinearity exists between Brachypodium distachyon L. chromos ...
... cluster. Mlm2033 and Mlm80 from einkorn wheat (T. monococcum L.) were two of the R genes belonging to this cluster. This study was initiated to fine map these two genes toward map-based cloning. Comparative genomics study showed that macrocolinearity exists between Brachypodium distachyon L. chromos ...
Fine Mapping of Two Wheat Powdery Mildew Resistance Genes
... cluster. Mlm2033 and Mlm80 from einkorn wheat (T. monococcum L.) were two of the R genes belonging to this cluster. This study was initiated to fine map these two genes toward map-based cloning. Comparative genomics study showed that macrocolinearity exists between Brachypodium distachyon L. chromos ...
... cluster. Mlm2033 and Mlm80 from einkorn wheat (T. monococcum L.) were two of the R genes belonging to this cluster. This study was initiated to fine map these two genes toward map-based cloning. Comparative genomics study showed that macrocolinearity exists between Brachypodium distachyon L. chromos ...
Module 1: Introduction
... when using Excel in bioinformatics BMC Bioinformatics. 2004 Jun 23;5:80 ...
... when using Excel in bioinformatics BMC Bioinformatics. 2004 Jun 23;5:80 ...
Mendelian or qualitative genetics
... progeny in a lifetime, and/or long durations between generations, it can be difficult to get enough progeny to do genetic analysis of a trait. A way around this problem is to do pedigree analysis of the family, looking back several generations. Symbols male female mating example: ...
... progeny in a lifetime, and/or long durations between generations, it can be difficult to get enough progeny to do genetic analysis of a trait. A way around this problem is to do pedigree analysis of the family, looking back several generations. Symbols male female mating example: ...
Rapid Selection of Multiple Gene Integrant for the Production of
... level of HV1 and HV2 was quite different inspite of the same copy number and integration locus. The amino acid and DNA sequence of them are different and this was the only reason of expression level difference. The previous reports about the expression of hirudin variants were studied about only one ...
... level of HV1 and HV2 was quite different inspite of the same copy number and integration locus. The amino acid and DNA sequence of them are different and this was the only reason of expression level difference. The previous reports about the expression of hirudin variants were studied about only one ...
Copy-number variation

Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.