Phenotypic effects and variations in the genetic material (part 1)
... These are an organism that gains extra copy of one or pair of chromosomes. a. Disomics (n+1) the gain of an extra copy of a chromosome. A disomic is an aberration of a haploid organism. Eg: In fungi, they can result from meiotic nondisjunction. In the fungus Neurospora (a haploid), an n − 1 meiotic ...
... These are an organism that gains extra copy of one or pair of chromosomes. a. Disomics (n+1) the gain of an extra copy of a chromosome. A disomic is an aberration of a haploid organism. Eg: In fungi, they can result from meiotic nondisjunction. In the fungus Neurospora (a haploid), an n − 1 meiotic ...
Journal of Applied Phycology
... The S. platensis recA gene has an identity of 72%, 68% and 60% when compared to the recA genes of Anabaena variabilis (Owttrim & Coleman, 1989) Synechococcus PCC 7002 (Murphy et al., 1990) and Escherichia coli (Sancar et al., 1980). Comparison of the amino acid sequences reveals an identity of 79%, ...
... The S. platensis recA gene has an identity of 72%, 68% and 60% when compared to the recA genes of Anabaena variabilis (Owttrim & Coleman, 1989) Synechococcus PCC 7002 (Murphy et al., 1990) and Escherichia coli (Sancar et al., 1980). Comparison of the amino acid sequences reveals an identity of 79%, ...
Complete Genome Sequence of Bacillus thuringiensis Strain 407 Cry-
... manipulation, and acrystalliferous strains may have higher transformation frequencies than do crystal-producing strains (1). B. thuringiensis strain 407 was isolated as a lepidopteran-active strain, and an acrystalliferous derivative, 407 Cry-, was produced through culturing at a high temperature (2 ...
... manipulation, and acrystalliferous strains may have higher transformation frequencies than do crystal-producing strains (1). B. thuringiensis strain 407 was isolated as a lepidopteran-active strain, and an acrystalliferous derivative, 407 Cry-, was produced through culturing at a high temperature (2 ...
Gene Flow Gene Flow Between Two Demes
... The equality depends upon the assumption of a 50:50 sexratio (which is true in this case), equal reproductive characteristics of both sexes (Nevm=Nevf), and equal m’s in ...
... The equality depends upon the assumption of a 50:50 sexratio (which is true in this case), equal reproductive characteristics of both sexes (Nevm=Nevf), and equal m’s in ...
Supplement Figures
... an approximation for the codon translation speed. The tAI index was developed mainly based on optimizing the translation efficiency of highly express genes. Two recent papers [15, 16] used evolutionary selection for translation efficiency as a means to learn the efficiency and coefficients of codon- ...
... an approximation for the codon translation speed. The tAI index was developed mainly based on optimizing the translation efficiency of highly express genes. Two recent papers [15, 16] used evolutionary selection for translation efficiency as a means to learn the efficiency and coefficients of codon- ...
Standard Genetic Nomenclature - Iowa State University Digital
... serological or nucleotide methods. The HGNC guideline recommends that 'allele designation should be written on the same line as gene symbol separated by an asterisk e.g. PGM1 * 1, the allele is printed as * 1 '. The wild-type allele can be denoted with a+ (e.g. MSTN+). Neither+ nor - symbols should ...
... serological or nucleotide methods. The HGNC guideline recommends that 'allele designation should be written on the same line as gene symbol separated by an asterisk e.g. PGM1 * 1, the allele is printed as * 1 '. The wild-type allele can be denoted with a+ (e.g. MSTN+). Neither+ nor - symbols should ...
Standard Genetic Nomenclature - Iowa State University Digital
... serological or nucleotide methods. The HGNC guideline recommends that 'allele designation should be written on the same line as gene symbol separated by an asterisk e.g. PGM1 * 1, the allele is printed as * 1 '. The wild-type allele can be denoted with a+ (e.g. MSTN+). Neither+ nor - symbols should ...
... serological or nucleotide methods. The HGNC guideline recommends that 'allele designation should be written on the same line as gene symbol separated by an asterisk e.g. PGM1 * 1, the allele is printed as * 1 '. The wild-type allele can be denoted with a+ (e.g. MSTN+). Neither+ nor - symbols should ...
Biology WarmUp: Meiosis Vocabulary Review 1. What does it
... Biology WarmUp: Meiosis Vocabulary Review 6. In fruit flies, the gene for star eye and speck wing are on the same chromosome, yet offspring from star-eyed, speckwinged parents often inherit star eyes without the speck wings. How is this possible? Make a diagram to illustrate the process that is res ...
... Biology WarmUp: Meiosis Vocabulary Review 6. In fruit flies, the gene for star eye and speck wing are on the same chromosome, yet offspring from star-eyed, speckwinged parents often inherit star eyes without the speck wings. How is this possible? Make a diagram to illustrate the process that is res ...
Professor Anthony Monaco - AWARES, the All Wales Autism Resource
... Are autism associated CNVs more likely to be sporadic “mutations” or inherited risk factors? ...
... Are autism associated CNVs more likely to be sporadic “mutations” or inherited risk factors? ...
LAPTh - CNRS
... • These transitions are conserved in mammalian genomes • Detection of more than one thousand putative origins active in germ-line cells ...
... • These transitions are conserved in mammalian genomes • Detection of more than one thousand putative origins active in germ-line cells ...
The Gene Ontology
... genes (more specific terms) or of smaller size (e.g.,<100) of user’s input gene list. In this case, the reliability is not as much as those fold enrichment scores obtained from larger numbers of genes ...
... genes (more specific terms) or of smaller size (e.g.,<100) of user’s input gene list. In this case, the reliability is not as much as those fold enrichment scores obtained from larger numbers of genes ...
Handout - 6 - CM - Outline Genomic Model for HL7 V2
... Allelic state and interpretive attributes ...
... Allelic state and interpretive attributes ...
Characterization of the Human Gene for a Newly Discovered
... Sequence analysis of this region revealed an open reading frame, bounded by consensus acceptor and donor splice sites, that predicted an amino acid sequence which was 56, 65, and 52% identical to the corresponding regions of the human CA I, CA II, and CA III proteins, respectively. This region of th ...
... Sequence analysis of this region revealed an open reading frame, bounded by consensus acceptor and donor splice sites, that predicted an amino acid sequence which was 56, 65, and 52% identical to the corresponding regions of the human CA I, CA II, and CA III proteins, respectively. This region of th ...
Inverse correlation between SMN1 and SMN2 copy numbers
... population, indicating the presence of chromosome 5s with two copies of SMN1.4,10 We meta-analyzed published data,3,4,8,10,13,14 and updated deduced SMN1 allele frequencies5 as follows: ‘zero-copy allele’ (chromosome 5 lacking SMN1 exon 7), 9.83 10 3; ‘one-copy allele’, 9.57 10 1; ‘two-copy alle ...
... population, indicating the presence of chromosome 5s with two copies of SMN1.4,10 We meta-analyzed published data,3,4,8,10,13,14 and updated deduced SMN1 allele frequencies5 as follows: ‘zero-copy allele’ (chromosome 5 lacking SMN1 exon 7), 9.83 10 3; ‘one-copy allele’, 9.57 10 1; ‘two-copy alle ...
Tutorial: RNA-Seq Analysis Part II (Tracks): Non-Specific
... Figure 10: The dot in the scatter plot corresponding to the gene "Rps13" and the corresponding region in the trackm list "zoomed-to-selection". area showing the visible reads by grabbing at the bottom of the track's editor and dragging it downwards. You will get a view similar to that in figure 11. ...
... Figure 10: The dot in the scatter plot corresponding to the gene "Rps13" and the corresponding region in the trackm list "zoomed-to-selection". area showing the visible reads by grabbing at the bottom of the track's editor and dragging it downwards. You will get a view similar to that in figure 11. ...
Human Apolipoprotein A-l-C-lll Gene Complex is Located on
... that they bind and transport lipid in the blood stream. Structurally the apolipoproteins that have been sequenced have all possessed amhipathic alpha-helical regions capable of interacting with aqueous and nonpolar environments.1 In 1977 Barker and Dayhoff30, using amino-acid sequence data available ...
... that they bind and transport lipid in the blood stream. Structurally the apolipoproteins that have been sequenced have all possessed amhipathic alpha-helical regions capable of interacting with aqueous and nonpolar environments.1 In 1977 Barker and Dayhoff30, using amino-acid sequence data available ...
A GENETIC EXPLANATION OF HOW GPRA IS INHERITED
... be affected, the animal must inherit 2 copies of the gene (genotype pp), 1 from each parent. Dogs with the genotype PP (normal) or Pp (carrier) will be clinically normal but the carrier will pass the affected gene to approximately half the offspring. As long as carriers (Pp) are mated to normal anim ...
... be affected, the animal must inherit 2 copies of the gene (genotype pp), 1 from each parent. Dogs with the genotype PP (normal) or Pp (carrier) will be clinically normal but the carrier will pass the affected gene to approximately half the offspring. As long as carriers (Pp) are mated to normal anim ...
Journal of Molecular Microbiology and Biotechnology
... ules can be distinguished: A1, located in BmyA; BmyB1, BmyB2, BmyB3, and BmyB4, located in BmyB, and C1 and C2, located in BmyC. The modules B1, B2, and C1 also contain epimerization domains, directing conversion of amino acids 2, 3, and 6 in a D-configuration. The last domain of this multienzyme s ...
... ules can be distinguished: A1, located in BmyA; BmyB1, BmyB2, BmyB3, and BmyB4, located in BmyB, and C1 and C2, located in BmyC. The modules B1, B2, and C1 also contain epimerization domains, directing conversion of amino acids 2, 3, and 6 in a D-configuration. The last domain of this multienzyme s ...
S. latifolia sex-linked genes, p. 1 Evolutionary strata on
... The ISVS method: A size comparison of homologous introns in previously described X-Y gene pairs in S. latifolia revealed that length variants are common (Figure 1). Among homologous introns in the SlX1/SlY1, SlssX/SlssY and DD44X/DD44Y gene pairs (ATANASSOV et al. 2001; FILATOV 2005c; MOORE et al. 2 ...
... The ISVS method: A size comparison of homologous introns in previously described X-Y gene pairs in S. latifolia revealed that length variants are common (Figure 1). Among homologous introns in the SlX1/SlY1, SlssX/SlssY and DD44X/DD44Y gene pairs (ATANASSOV et al. 2001; FILATOV 2005c; MOORE et al. 2 ...
RNA-guided gene drives can efficiently bias inheritance in wild yeast
... observed a perfect 4:0 ratio of red:cream haploids, confirming that all copies of the ADE2 locus were disrupted. In contrast, 18 cream-colored cas9— diploids yielded a 2:2 red:cream ratio, indicating normal inheritance of the inactivated drive and the wild-type alleles (Fig. 2D). To determine whethe ...
... observed a perfect 4:0 ratio of red:cream haploids, confirming that all copies of the ADE2 locus were disrupted. In contrast, 18 cream-colored cas9— diploids yielded a 2:2 red:cream ratio, indicating normal inheritance of the inactivated drive and the wild-type alleles (Fig. 2D). To determine whethe ...
Host-Plasmid Interactions in Saccharomyces
... Copy number of chimaeric plasmids in strains of drflerent ploidy The most plausible explanation for the observed increase in the stability of YRp7M with increasing ploidy is that its copy number increases proportionately, thus decreasing the probability of segregating plasmid-free cells in the absen ...
... Copy number of chimaeric plasmids in strains of drflerent ploidy The most plausible explanation for the observed increase in the stability of YRp7M with increasing ploidy is that its copy number increases proportionately, thus decreasing the probability of segregating plasmid-free cells in the absen ...
Identification of Mga1, a G‐protein α‐subunit gene involved in
... have been identified (Shimizu et al., 2007; Chen et al., 2008b). Based on the genetic information, a genetic modification method has also been proposed (Fu et al., 2007; Jia et al., 2010). Secondary metabolite production is controlled at an upper hierarchical level by many global mechanisms, in whic ...
... have been identified (Shimizu et al., 2007; Chen et al., 2008b). Based on the genetic information, a genetic modification method has also been proposed (Fu et al., 2007; Jia et al., 2010). Secondary metabolite production is controlled at an upper hierarchical level by many global mechanisms, in whic ...
Enhanced Detection of Longer Insertions and Deletions in Clinical
... found in the human genome and substantial amount of research, such as that by the International HapMap Consortium, has been focused on accurately mapping and identifying SNVs for human genetic variation studies [8]. However, in spite of being the second most common type of genomic alterations [9], i ...
... found in the human genome and substantial amount of research, such as that by the International HapMap Consortium, has been focused on accurately mapping and identifying SNVs for human genetic variation studies [8]. However, in spite of being the second most common type of genomic alterations [9], i ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.