The Effect of a Coat Colour-Associated Genes Polymorphism on
... In horses the KIT gene is also the candidate gene for roan coat colour (Marklund et al., 1999). Horses of roan phenotype are characterized by grey coat colour that results from blending the basic colour with white bristles in the thorax, neck, and partially limb areas. Roan coat colour in horses is ...
... In horses the KIT gene is also the candidate gene for roan coat colour (Marklund et al., 1999). Horses of roan phenotype are characterized by grey coat colour that results from blending the basic colour with white bristles in the thorax, neck, and partially limb areas. Roan coat colour in horses is ...
Function of lanI in regulation of landomycin A biosynthesis in
... Stock 1997; Harrison-McMonagle et al. 1999). Therefore, these transcriptional factors were grouped into SARP family (for Streptomyces antibiotics regulatory proteins, Wietzorrek and Bibb 1997). SARP genes were found within almost all biosynthesis gene clusters governing aromatic polyketides producti ...
... Stock 1997; Harrison-McMonagle et al. 1999). Therefore, these transcriptional factors were grouped into SARP family (for Streptomyces antibiotics regulatory proteins, Wietzorrek and Bibb 1997). SARP genes were found within almost all biosynthesis gene clusters governing aromatic polyketides producti ...
Sequencing Crop Genomes - Tropical Life Sciences Research
... shotgun sequencing strategy so that each sequenced clone can be associated with a specific position on the genetic map (http://rgp.dna.affrc.go.jp/IRGSP/ index.html). In addition, two independent groups published the draft genome of both indica (Yu et al. 2002) and japonica (Goff et al. 2002) sub-sp ...
... shotgun sequencing strategy so that each sequenced clone can be associated with a specific position on the genetic map (http://rgp.dna.affrc.go.jp/IRGSP/ index.html). In addition, two independent groups published the draft genome of both indica (Yu et al. 2002) and japonica (Goff et al. 2002) sub-sp ...
Interactive Visualization of Gene Regulatory Networks with
... Westenberg, Van Hijum, Lulko, Kuipers, Roerdink ...
... Westenberg, Van Hijum, Lulko, Kuipers, Roerdink ...
Identify differential APA usage from RNA
... The gtf file should have an attribute (metadata column for the GRanges object) called “gene id” that ends with “ PRE” or “ POST” to address respectively the short and the long isoforms. An element in the annotation is considered “PRE” (i.e. common to the short and long isoform of the transcript) if ...
... The gtf file should have an attribute (metadata column for the GRanges object) called “gene id” that ends with “ PRE” or “ POST” to address respectively the short and the long isoforms. An element in the annotation is considered “PRE” (i.e. common to the short and long isoform of the transcript) if ...
Slide 1 - Faculty Web Pages
... 1.) For good form, write down alleles for genes 1, 2, and 3 at top of page. 2.) Determine genotypes for heterozygous parent and cross-progeny, based on the phenotypes. You should already know the genotype of the homozygous parent Do the genotypes give chromosome information? 3.) Write down chromosom ...
... 1.) For good form, write down alleles for genes 1, 2, and 3 at top of page. 2.) Determine genotypes for heterozygous parent and cross-progeny, based on the phenotypes. You should already know the genotype of the homozygous parent Do the genotypes give chromosome information? 3.) Write down chromosom ...
srep09383-s1
... E. coli ET12567 cells carrying pUB3077. The resultant exconjugants were selected on LB agar containing tetracycline (20 µg mL-1), and then plasmids were extracted to confirm successful DNA transfer. The conjugation efficiencies between E. coli and B. subtilis were showed in Table S6. Unfortunately, ...
... E. coli ET12567 cells carrying pUB3077. The resultant exconjugants were selected on LB agar containing tetracycline (20 µg mL-1), and then plasmids were extracted to confirm successful DNA transfer. The conjugation efficiencies between E. coli and B. subtilis were showed in Table S6. Unfortunately, ...
Chromatin: A sticky silence
... forty fold lower than at the telomeres, depending on the relative strengths of the silencer and promoter tested. As silencer-binding factors function primarily by targeting Sir1p, Sir3p and Sir4p, one can bypass the need for a silencer to repress a reporter gene by replacing it with a Gal4p-binding ...
... forty fold lower than at the telomeres, depending on the relative strengths of the silencer and promoter tested. As silencer-binding factors function primarily by targeting Sir1p, Sir3p and Sir4p, one can bypass the need for a silencer to repress a reporter gene by replacing it with a Gal4p-binding ...
UCSC genome support forum
... 2. View this region in the Browser: 2.1. Navigate to http://genome.ucsc.edu/cgi-bin/hgGateway 2.2. Enter your assembly of choice and enter your coordinates in the “search term” box 2.3. Click the “submit” button 3. In the blue navigation bar at the top of the screen, click “View/DNA” 4. Click the “g ...
... 2. View this region in the Browser: 2.1. Navigate to http://genome.ucsc.edu/cgi-bin/hgGateway 2.2. Enter your assembly of choice and enter your coordinates in the “search term” box 2.3. Click the “submit” button 3. In the blue navigation bar at the top of the screen, click “View/DNA” 4. Click the “g ...
The Incompatible Desiderata of Gene Cluster Properties
... that is known is often based (somewhat circularly) on inferred homology of chromosomal segments. The properties underlying existing cluster definitions are generally not stated, and the dimensions along which they differ have been analyzed in only a cursory manner. As a result, the formal tradeoffs ...
... that is known is often based (somewhat circularly) on inferred homology of chromosomal segments. The properties underlying existing cluster definitions are generally not stated, and the dimensions along which they differ have been analyzed in only a cursory manner. As a result, the formal tradeoffs ...
Frequent Loss of Heterozygosity at the TEL Gene Locus
... fusion partners have also been identified for the MLL gene, which is frequently rearranged in leukemias with translocations involving 11q23.I4 A recent addition to this group of chimeric transcription factors is the TEL-AMLl fusion, which is the consequence of the t(12;21)(p13;q22) associated with c ...
... fusion partners have also been identified for the MLL gene, which is frequently rearranged in leukemias with translocations involving 11q23.I4 A recent addition to this group of chimeric transcription factors is the TEL-AMLl fusion, which is the consequence of the t(12;21)(p13;q22) associated with c ...
The Gene Gateway Workbook
... The Gene Gateway Workbook is a collection of activities with screenshots and step-by-step instructions designed to introduce new users to genetic disorder and bioinformatics resources freely available on the Web. It should take about 3 hours to complete all five activities. The workbook activities w ...
... The Gene Gateway Workbook is a collection of activities with screenshots and step-by-step instructions designed to introduce new users to genetic disorder and bioinformatics resources freely available on the Web. It should take about 3 hours to complete all five activities. The workbook activities w ...
What are SNPs
... change in the DNA code SNPs occur with various allele frequencies. Those in the 20-40% range are useful for genetic mapping. Those at frequencies between 1% and 20% may be used with candidate gene approaches. Usually bi-allelic. Changes at 〈1% are called variants ...
... change in the DNA code SNPs occur with various allele frequencies. Those in the 20-40% range are useful for genetic mapping. Those at frequencies between 1% and 20% may be used with candidate gene approaches. Usually bi-allelic. Changes at 〈1% are called variants ...
Identifying Signatures of Natural Selection in Tibetan Data
... hypoxia. We looked across each chromosome to identify genomic regions with previously unknown function with respect to altitude phenotypes. In addition, groups of genes functioning in oxygen metabolism and sensing were examined to test the hypothesis that particular pathways have been involved in ge ...
... hypoxia. We looked across each chromosome to identify genomic regions with previously unknown function with respect to altitude phenotypes. In addition, groups of genes functioning in oxygen metabolism and sensing were examined to test the hypothesis that particular pathways have been involved in ge ...
Peer-reviewed Article PDF
... gene is on chromosome 12 and presumably on the distal part of 12q [13]. By in situ hybridization, the assignment of the PAH gene was narrowed to chromosome 12q22-q24.1 [14]. Most PAH missense mutations impair enzyme activity by causing increased protein instability and aggregation. An alternative me ...
... gene is on chromosome 12 and presumably on the distal part of 12q [13]. By in situ hybridization, the assignment of the PAH gene was narrowed to chromosome 12q22-q24.1 [14]. Most PAH missense mutations impair enzyme activity by causing increased protein instability and aggregation. An alternative me ...
Diagnostic Clinical Genome and Exome Sequencing
... altered function of a gene, and variants previously reported to cause disease.10,11 CGES is most useful for the detection of single-nucleotide substitutions and insertions or deletions of 8 to 10 nucleotides or smaller; it is less accurate for other types of genomic variation (Table 1). The yield of ...
... altered function of a gene, and variants previously reported to cause disease.10,11 CGES is most useful for the detection of single-nucleotide substitutions and insertions or deletions of 8 to 10 nucleotides or smaller; it is less accurate for other types of genomic variation (Table 1). The yield of ...
PDF
... Fig. 1. Modified DamID approach to identify DSXbinding regions. (A)Schematic drawing of the flip-on Dam-fusion constructs. The proteins are expressed from the basal level of the UAS sequence after the FRTstop-FRT cassette is removed by expression of FLPase. (B)Example of an Illumina sequencing lib ...
... Fig. 1. Modified DamID approach to identify DSXbinding regions. (A)Schematic drawing of the flip-on Dam-fusion constructs. The proteins are expressed from the basal level of the UAS sequence after the FRTstop-FRT cassette is removed by expression of FLPase. (B)Example of an Illumina sequencing lib ...
Word Pro - Sezutsu.lwp
... chi-like sequence. In the Apf gene, the AGG amino acid triplet corresponds to a chi-like sequence. The near lack of chi in the Rff gene may be associated with the much lower content of Ala residue in the NPABs. Fibroins are important candidates for the production of transgenic silkworms that would s ...
... chi-like sequence. In the Apf gene, the AGG amino acid triplet corresponds to a chi-like sequence. The near lack of chi in the Rff gene may be associated with the much lower content of Ala residue in the NPABs. Fibroins are important candidates for the production of transgenic silkworms that would s ...
Phenotypic effects and variations in the genetic material (part 1)
... These are an organism that gains extra copy of one or pair of chromosomes. a. Disomics (n+1) the gain of an extra copy of a chromosome. A disomic is an aberration of a haploid organism. Eg: In fungi, they can result from meiotic nondisjunction. In the fungus Neurospora (a haploid), an n − 1 meiotic ...
... These are an organism that gains extra copy of one or pair of chromosomes. a. Disomics (n+1) the gain of an extra copy of a chromosome. A disomic is an aberration of a haploid organism. Eg: In fungi, they can result from meiotic nondisjunction. In the fungus Neurospora (a haploid), an n − 1 meiotic ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.