Analysis of Tetrads from the yeast Saccaromyces
... Analysis of Tetrads from the yeast Saccaromyces cerevisiae When normally haploid yeast cells of two different mating types encounter each other, they fuse to form a diploid zygote (this constitutes a cross), which immediately undergoes meiosis to regenerate four individual haploid spores – a tetrad ...
... Analysis of Tetrads from the yeast Saccaromyces cerevisiae When normally haploid yeast cells of two different mating types encounter each other, they fuse to form a diploid zygote (this constitutes a cross), which immediately undergoes meiosis to regenerate four individual haploid spores – a tetrad ...
Genome sequence of Aspergillus luchuensis
... 513.88. We estimated the putative amino acid sequences from the A. luchuensis genome sequence based on the fact that the amino acid sequences around the catalytic residues in the active sites of proteases are conserved.29 Black Aspergillus, A. luchuensis, and A. niger possess many acidic proteases. ...
... 513.88. We estimated the putative amino acid sequences from the A. luchuensis genome sequence based on the fact that the amino acid sequences around the catalytic residues in the active sites of proteases are conserved.29 Black Aspergillus, A. luchuensis, and A. niger possess many acidic proteases. ...
Chromatin Domain Boundaries: Defining the Functional Domains in
... associated with the protein of interest. ChIP can be combined with micro array to identify such sites on a genome level a technique termed ChIP-on-chip [26]. In this method ChIP is performed as usual and the DNA is analyzed using a chip of whole genome tiling array. This technique can be used to ide ...
... associated with the protein of interest. ChIP can be combined with micro array to identify such sites on a genome level a technique termed ChIP-on-chip [26]. In this method ChIP is performed as usual and the DNA is analyzed using a chip of whole genome tiling array. This technique can be used to ide ...
Jounral of Bacteriology
... sequence reads (5.76 ⫻ coverage) from our shot gun approach (see Materials and Methods). The total length of the nonredundant sequence formed by all contigs was 3,818 kb, which is slightly less than the size of the B. subtilis 168 genome of 4,214 kb (16). We identified 2,980 genes (72.7%) on the FZB ...
... sequence reads (5.76 ⫻ coverage) from our shot gun approach (see Materials and Methods). The total length of the nonredundant sequence formed by all contigs was 3,818 kb, which is slightly less than the size of the B. subtilis 168 genome of 4,214 kb (16). We identified 2,980 genes (72.7%) on the FZB ...
Population Differences in Transcript
... genome, respectively. Although it has been suggested that SNPs residing in transcription factors (TFs) have no significant attributable effect on gene expression variation [11], it is unknown whether a variant that affects the genes regulated by a TF operates through a system of regulated pathways. ...
... genome, respectively. Although it has been suggested that SNPs residing in transcription factors (TFs) have no significant attributable effect on gene expression variation [11], it is unknown whether a variant that affects the genes regulated by a TF operates through a system of regulated pathways. ...
milova_032405 - Microarray Facility
... Gene Ontology annotation for all GO IDs is kept in three different information fields: biological processes, molecular function and cellular compartment. For each of the fields all available annotation was prefiltered with redundancy check and concatenated. Kate Milova ...
... Gene Ontology annotation for all GO IDs is kept in three different information fields: biological processes, molecular function and cellular compartment. For each of the fields all available annotation was prefiltered with redundancy check and concatenated. Kate Milova ...
Driscoll Katee Driscoll Dr. Ely Genetics October 20, 2013 Effects of
... studies and their own experiments that showed that super-long CAG repeat lengths could in fact impact gene expression and transcription levels. In addition to this, one of the most important observations of longer than normal CAG repeat length is its effect on the age of onset. The Huntington’s Dise ...
... studies and their own experiments that showed that super-long CAG repeat lengths could in fact impact gene expression and transcription levels. In addition to this, one of the most important observations of longer than normal CAG repeat length is its effect on the age of onset. The Huntington’s Dise ...
coexpression database for animal species by
... were selected (total mapped counts >10 000 000), resulting 5626, 3746 and 754 runs for human, mouse and fly, respectively. The mapped counts were summed for each gene model and used as the gene expression value. Genes with lower levels of expression; i.e. with average counts across all runs <30, wer ...
... were selected (total mapped counts >10 000 000), resulting 5626, 3746 and 754 runs for human, mouse and fly, respectively. The mapped counts were summed for each gene model and used as the gene expression value. Genes with lower levels of expression; i.e. with average counts across all runs <30, wer ...
- Global Genes
... • Turn food into energy for cells • Make the nerves transmit signals from the body to the brain and back again • Take oxygen from inhaling air and moves it to cells • Perform all the other jobs needed for the body to develop and repair • To make it easier to zip up tight jeans (We wish!) Many o ...
... • Turn food into energy for cells • Make the nerves transmit signals from the body to the brain and back again • Take oxygen from inhaling air and moves it to cells • Perform all the other jobs needed for the body to develop and repair • To make it easier to zip up tight jeans (We wish!) Many o ...
Molecular Evolution of the CMT1A-REP Region: A Human
... a 1.5-Mb region containing a dosage-sensitive gene, peripheral nerve protein-22 (PMP22). Unequal meiotic crossover mediated by misalignment of proximal and distal copies of the CMT1A-REP in humans leads to a 1.5-Mb duplication or deletion associated with two common peripheral nerve diseases, Charcot ...
... a 1.5-Mb region containing a dosage-sensitive gene, peripheral nerve protein-22 (PMP22). Unequal meiotic crossover mediated by misalignment of proximal and distal copies of the CMT1A-REP in humans leads to a 1.5-Mb duplication or deletion associated with two common peripheral nerve diseases, Charcot ...
Initiation of recombination suppression and PAR formation during
... suppression of recombination with the X. In the early stages of sex-chromosome differentiation, it is suggested that interactions between sex-determining genes and sexually antagonistic genes can drive selection for reduced recombination via gradual reduction of crossover frequencies, due to the spr ...
... suppression of recombination with the X. In the early stages of sex-chromosome differentiation, it is suggested that interactions between sex-determining genes and sexually antagonistic genes can drive selection for reduced recombination via gradual reduction of crossover frequencies, due to the spr ...
Chapter 1 - Bioinformatics Research Center
... sequence tags, simple repeats, or restriction enzyme polymorphisms), but may include phenotypes associated with Mendelian loci. In diploid organisms, genetic maps are typically assembled from data on the co-segregation of genetic markers either in pedigrees or in the progeny of controlled crosses. T ...
... sequence tags, simple repeats, or restriction enzyme polymorphisms), but may include phenotypes associated with Mendelian loci. In diploid organisms, genetic maps are typically assembled from data on the co-segregation of genetic markers either in pedigrees or in the progeny of controlled crosses. T ...
Gene Duplication - Semantic Scholar
... (or genome) duplication. Zhang 2003 summarizes the main features of these mechanisms. Kaessmann, et al. 2009 provides detailed information about retroposition-mediated gene duplication. Most genetics textbooks, including Klug, et al. 2009, describe detailed mechanisms ...
... (or genome) duplication. Zhang 2003 summarizes the main features of these mechanisms. Kaessmann, et al. 2009 provides detailed information about retroposition-mediated gene duplication. Most genetics textbooks, including Klug, et al. 2009, describe detailed mechanisms ...
externial ophtlhalmiioplegila has been reported as inherited in two
... family is recessive and sex-linked. As far as we have been able to discover in the literature there is no earlier reference to inheritance of this ty-pe for this particular disease. The clinical and neurological examination carried out by one of us (J. C. (). de Z.) on all fourteen living members of ...
... family is recessive and sex-linked. As far as we have been able to discover in the literature there is no earlier reference to inheritance of this ty-pe for this particular disease. The clinical and neurological examination carried out by one of us (J. C. (). de Z.) on all fourteen living members of ...
Woolfe, 2005
... CNEs found in clusters, in front of transdev genes CNEs act at large distances from coding sequence The relative order and positions of CNEs are conserved No vertebrate CNEs were found in invertebrates, even though the genes had clear homologs Many of these results are paralleled by a similar paper ...
... CNEs found in clusters, in front of transdev genes CNEs act at large distances from coding sequence The relative order and positions of CNEs are conserved No vertebrate CNEs were found in invertebrates, even though the genes had clear homologs Many of these results are paralleled by a similar paper ...
Comparative Sequence Analysis of a Region on Human
... (Juliusson and Gahrton, 1993; Oscier, 1994). We have recently defined a minimally deleted region of 130 kb centromeric to the marker D13S272 on chromosome 13q (Corcoran et al., 1998), and in an extension of these studies, we identified two neighbouring genes, termed LEU1 and LEU2, covering a major d ...
... (Juliusson and Gahrton, 1993; Oscier, 1994). We have recently defined a minimally deleted region of 130 kb centromeric to the marker D13S272 on chromosome 13q (Corcoran et al., 1998), and in an extension of these studies, we identified two neighbouring genes, termed LEU1 and LEU2, covering a major d ...
S1 Document.
... QuikChange site-directed mutagenesis kit (Agilent Technologies). Primers used for mutagenesis are listed in Table S1. ...
... QuikChange site-directed mutagenesis kit (Agilent Technologies). Primers used for mutagenesis are listed in Table S1. ...
Fluorescence in Situ Hybridization Evaluation of c-erbB
... stepwise progression of solid tumors. Moreover, oncogene amplification may be associated with aggressive growth and may be a useful indicator of progression and prognosis in various human cancers (1). A few studies using FISH showed c-erbB-2 gene amplification in bladder cancers, and the clinical si ...
... stepwise progression of solid tumors. Moreover, oncogene amplification may be associated with aggressive growth and may be a useful indicator of progression and prognosis in various human cancers (1). A few studies using FISH showed c-erbB-2 gene amplification in bladder cancers, and the clinical si ...
Simulating evolution by gene duplication of protein features that
... figure) in the gene coding for the protein before a null mutation occurs elsewhere in the gene (indicated by a red “X”), then several amino acid residues will have been altered and the new selectable MR feature will have been successfully built in the protein (indicated by the greenshaded area). By ...
... figure) in the gene coding for the protein before a null mutation occurs elsewhere in the gene (indicated by a red “X”), then several amino acid residues will have been altered and the new selectable MR feature will have been successfully built in the protein (indicated by the greenshaded area). By ...
Comparison between Human and Mouse genomes
... Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. Automated partial DNA sequencing was conducted on more than 600 randomly selected human brain complementary DNA (cDNA) clones to generate expressed sequence tags (ESTs). ESTs have applications in the discovery of new hum ...
... Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. Automated partial DNA sequencing was conducted on more than 600 randomly selected human brain complementary DNA (cDNA) clones to generate expressed sequence tags (ESTs). ESTs have applications in the discovery of new hum ...
timeline
... resulting mice, when fed with extra zinc, grow to be huge, and the technique paves the way for a wave of genetic analysis using transgenic mice. ...
... resulting mice, when fed with extra zinc, grow to be huge, and the technique paves the way for a wave of genetic analysis using transgenic mice. ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.