Slide 1 - Elsevier
... representing the deprived eye (dark stripes) and an expansion of the columns of the nondeprived eye (light stripes). (C) Aschematic representation of ocular dominance column development represents the way in which a gradual segregation ocular dominance column could lead to the end of the critical pe ...
... representing the deprived eye (dark stripes) and an expansion of the columns of the nondeprived eye (light stripes). (C) Aschematic representation of ocular dominance column development represents the way in which a gradual segregation ocular dominance column could lead to the end of the critical pe ...
Learning sensory maps with real-world stimuli in real time using a
... in the physiology of the visual system where the optimality of the tuning of a neuron seems to be directly reflected in its response latency to a stimulus [24]. Given the above mechanism this would imply that the optimally tuned neurons prevent further learning by other neurons in the map. Synaptic ...
... in the physiology of the visual system where the optimality of the tuning of a neuron seems to be directly reflected in its response latency to a stimulus [24]. Given the above mechanism this would imply that the optimally tuned neurons prevent further learning by other neurons in the map. Synaptic ...
Neuromodulation of in Layer II Medial Entorhinal Cortex I
... frequency and resonance strength, following application of cholinergic agonists, was at least in part the result of changes in Ih. We have extended this result in the current study through pharmacological isolation of Ih in voltage clamp. The role of h current is further supported here by our voltag ...
... frequency and resonance strength, following application of cholinergic agonists, was at least in part the result of changes in Ih. We have extended this result in the current study through pharmacological isolation of Ih in voltage clamp. The role of h current is further supported here by our voltag ...
Substrate Stiffness and Adhesivity Influence Neuron Axonal Growth
... tissue [14,15]. The extracellular-protein fibronectin is also known to support survival and migration of neurons during their development [16]. While it has been shown that axon differentiation orients in the direction of increasing densities of such extracellular ligands [17], less is understood ab ...
... tissue [14,15]. The extracellular-protein fibronectin is also known to support survival and migration of neurons during their development [16]. While it has been shown that axon differentiation orients in the direction of increasing densities of such extracellular ligands [17], less is understood ab ...
Self-organization and interareal networks™in™the™primate cortex
... corticogenesis cannot be understood uniquely in terms of molecular prespecification but must also take into account the internal and external environmental factors that modulate organization as cortical development unfolds. The developing sensory apparatus produces environmental information from whi ...
... corticogenesis cannot be understood uniquely in terms of molecular prespecification but must also take into account the internal and external environmental factors that modulate organization as cortical development unfolds. The developing sensory apparatus produces environmental information from whi ...
REGENERATION OF AN IDENTIFIED CENTRAL NEURON IN THE
... If any growth also occurred from the axon, there was a reciprocal relationship between the extent of dendritic and axonal sprouting. On the other hand, axotomy distant to the cell body induces sprouting only from the axon and does not alter the dendritic structure of the MGI. After crushing the vent ...
... If any growth also occurred from the axon, there was a reciprocal relationship between the extent of dendritic and axonal sprouting. On the other hand, axotomy distant to the cell body induces sprouting only from the axon and does not alter the dendritic structure of the MGI. After crushing the vent ...
Functional Motifs Composed of Morphologically Homologous
... little is known about functional relationships among segmental homologs. Here we investigated the electrophysiological connectivity between the Mauthner cell (M-cell), a pair of giant RSNs in segment 4 (r4) that are known to trigger fast escape behavior, and different series of homologous RSNs in r4 ...
... little is known about functional relationships among segmental homologs. Here we investigated the electrophysiological connectivity between the Mauthner cell (M-cell), a pair of giant RSNs in segment 4 (r4) that are known to trigger fast escape behavior, and different series of homologous RSNs in r4 ...
Topography of Modular Subunits in the Mushroom Bodies of the
... The mushroom body (MB), a conspicuous neuropil structure in the insect brain, is implicated in associative memory and in some aspects of motor control. Intrinsic neurons of the MB (Kenyon cells) extend dendrites into the calyx, and their axons run through the pedunculus and then bifurcate to form th ...
... The mushroom body (MB), a conspicuous neuropil structure in the insect brain, is implicated in associative memory and in some aspects of motor control. Intrinsic neurons of the MB (Kenyon cells) extend dendrites into the calyx, and their axons run through the pedunculus and then bifurcate to form th ...
Rhythmicity, randomness and synchrony in climbing fiber signals
... spikes recorded from a Purkinje cell with ‘typical rhythmicity’ in an awake rat [13]. A significant peak at 100 ms shows that complex spikes sometimes occur in doublets at an interval of w100 ms. A single complex spike evokes only one or two spikes [38] in a Purkinje cell axon that descends to the c ...
... spikes recorded from a Purkinje cell with ‘typical rhythmicity’ in an awake rat [13]. A significant peak at 100 ms shows that complex spikes sometimes occur in doublets at an interval of w100 ms. A single complex spike evokes only one or two spikes [38] in a Purkinje cell axon that descends to the c ...
Proc. Natl. Acad. Sci. USA
... correlated responses before the lesion (11 cells) was larger than that after the lesion for set A (5 cells) or set B (1 cell), and the percentages of the correlated cells were statistically significantly different (x2 5 7.06, P , 0.05). The frequency distributions of PI after the lesion (Fig. 4B) al ...
... correlated responses before the lesion (11 cells) was larger than that after the lesion for set A (5 cells) or set B (1 cell), and the percentages of the correlated cells were statistically significantly different (x2 5 7.06, P , 0.05). The frequency distributions of PI after the lesion (Fig. 4B) al ...
Signal Integration in Thalamus: Labeled Lines Go
... merged and the various integration strategies they employ at each processing station serve as bottlenecks to the types and range of perceptions the brain can create and thus is important to our experience of the world. In this issue of Neuron, Roska and co-workers (Rompani et al., 2017) reveal the s ...
... merged and the various integration strategies they employ at each processing station serve as bottlenecks to the types and range of perceptions the brain can create and thus is important to our experience of the world. In this issue of Neuron, Roska and co-workers (Rompani et al., 2017) reveal the s ...
Poster Example
... The study of neuron-specific factors requires pure neuronal cultures. However, the absence of glia can affect the physiology of neurons negatively. This study compared three different treatments of neuronal cultures in order to find a treatment that reversed the deleterious effects of removing glia ...
... The study of neuron-specific factors requires pure neuronal cultures. However, the absence of glia can affect the physiology of neurons negatively. This study compared three different treatments of neuronal cultures in order to find a treatment that reversed the deleterious effects of removing glia ...
Use of a Recombinant Pseudorabies Virus to
... these 250 lm wide bands of the MIs were encountered. In the left hemisphere, this 250 lm wide cortical band contained the penetration channel too (Fig. 1). To check whether the infection pattern exceeded the 250 lm wide band, one animal randomly selected from the n7x group and one from the sham-oper ...
... these 250 lm wide bands of the MIs were encountered. In the left hemisphere, this 250 lm wide cortical band contained the penetration channel too (Fig. 1). To check whether the infection pattern exceeded the 250 lm wide band, one animal randomly selected from the n7x group and one from the sham-oper ...
PDF file
... The following technical characteristics required by developmental learning make such work challenging: (1) Integrate both bottom-up and top-down attention; (2) Integrate attentionbased recognition and object-based spacial attention interactively; (3) Enable supervised and unsupervised learning in an ...
... The following technical characteristics required by developmental learning make such work challenging: (1) Integrate both bottom-up and top-down attention; (2) Integrate attentionbased recognition and object-based spacial attention interactively; (3) Enable supervised and unsupervised learning in an ...
HECTtype E3 ubiquitin ligases in nerve cell development and
... Based on their mode of action, two families of E3 ligases are distinguished, i.e. the Really Interesting New Gene (RING) and the Homologous to E6-AP C-terminus (HECT) type. Whereas RING type enzymes bring the ubiquitin-E2 complex into the molecular vicinity of the substrate and facilitate ubiquitin ...
... Based on their mode of action, two families of E3 ligases are distinguished, i.e. the Really Interesting New Gene (RING) and the Homologous to E6-AP C-terminus (HECT) type. Whereas RING type enzymes bring the ubiquitin-E2 complex into the molecular vicinity of the substrate and facilitate ubiquitin ...
Specificity in Inhibitory Systems Associated with Prefrontal Pathways to
... not understood. We addressed this issue using as a model system the pathways from the functionally distinct prefrontal areas 10 and 32 to auditory association cortex, and investigated their relationship to inhibitory neurons labeled for calbindin (CB) or parvalbumin (PV), which differ in mode of inh ...
... not understood. We addressed this issue using as a model system the pathways from the functionally distinct prefrontal areas 10 and 32 to auditory association cortex, and investigated their relationship to inhibitory neurons labeled for calbindin (CB) or parvalbumin (PV), which differ in mode of inh ...
Synapse
... •Binding of transmitter to its receptor→ G- protein is activated (by replacement of its GDP with GTP) → separates the α component from the G-protein. •The separated active α component can perform; 1. Opening specific ion channels e.g. 2nd- messenger gated K channels 2. Activation of particular en ...
... •Binding of transmitter to its receptor→ G- protein is activated (by replacement of its GDP with GTP) → separates the α component from the G-protein. •The separated active α component can perform; 1. Opening specific ion channels e.g. 2nd- messenger gated K channels 2. Activation of particular en ...
Grid Cell Firing May Arise From Interference of Theta Frequency
... 2005, 2007; Giocomo et al., 2007) indicate the importance of novel intrinsic single cell mechanisms for representing information about space and time. This mechanism involves the interaction of intrinsic subthreshold oscillations within a single neuron. Prominent subthreshold membrane potential osci ...
... 2005, 2007; Giocomo et al., 2007) indicate the importance of novel intrinsic single cell mechanisms for representing information about space and time. This mechanism involves the interaction of intrinsic subthreshold oscillations within a single neuron. Prominent subthreshold membrane potential osci ...
Expression of Cux-1 and Cux-2 in the Subventricular Zone and
... The mammalian cortex is organized into six layers, with each layer containing neurons that share common morphologies, patterns of connectivity, and development. The cortex develops from an early neuroepithelial precursor population that lines the ventricle of the two telencephalic vesicles. During c ...
... The mammalian cortex is organized into six layers, with each layer containing neurons that share common morphologies, patterns of connectivity, and development. The cortex develops from an early neuroepithelial precursor population that lines the ventricle of the two telencephalic vesicles. During c ...
I. MITRAL CELLS OF THE OLFACTORY BULB OF THE LIZARD S. Llahi,
... somata are often parallelly arranged to the medial surface, but at more caudal levels, perpendicular or tangential orientations can easily be observed. In the AOB mitral cells can give rise to more than one primary dendrite and corresponding tuft (fig. 4B,C) in the glomerular layer (one tuft within ...
... somata are often parallelly arranged to the medial surface, but at more caudal levels, perpendicular or tangential orientations can easily be observed. In the AOB mitral cells can give rise to more than one primary dendrite and corresponding tuft (fig. 4B,C) in the glomerular layer (one tuft within ...
Some insights into computational models of (patho)physiological
... determines the lowest threshold. Instead they pointed to biophysical properties of axonal channels that are critical to action potential initiation. Initiation of dendritic spikes was investigated in a computational study by Mainen ([24]). Apart from models of membranes with voltage dependent conduc ...
... determines the lowest threshold. Instead they pointed to biophysical properties of axonal channels that are critical to action potential initiation. Initiation of dendritic spikes was investigated in a computational study by Mainen ([24]). Apart from models of membranes with voltage dependent conduc ...
Location and connectivity determine GABAergic interneuron survival in the brains... South Hampshire sheep with CLN6 neuronal ceroid lipofuscinosis
... This study of regional disease related changes in the distribution of interneuron populations from 12 days to mature disease revealed a distinctive pattern of change for each calcium binding protein. Loss of neurons positive to parvalbumin from the affected cortex became apparent at four months of a ...
... This study of regional disease related changes in the distribution of interneuron populations from 12 days to mature disease revealed a distinctive pattern of change for each calcium binding protein. Loss of neurons positive to parvalbumin from the affected cortex became apparent at four months of a ...
Chemosensory Systems
... cells and granule cells are common. The mitral cell and granule cell layers form the deepest layers of the olfactory bulb [Fig. 32-7B]. Mitral cells respond selectively to odor quality and intensity. The bulb is divided into functional regions, specialized for processing distinct odor chemicals. E.g ...
... cells and granule cells are common. The mitral cell and granule cell layers form the deepest layers of the olfactory bulb [Fig. 32-7B]. Mitral cells respond selectively to odor quality and intensity. The bulb is divided into functional regions, specialized for processing distinct odor chemicals. E.g ...
A local circuit approach to understanding integration of
... long-range intracortical inputs is known to be context-dependent: the same long-range stimulus can either facilitate or suppress responses, depending on the level of local activation. By constructing a large-scale model of primary visual cortex, we demonstrate that this effect can be understood in t ...
... long-range intracortical inputs is known to be context-dependent: the same long-range stimulus can either facilitate or suppress responses, depending on the level of local activation. By constructing a large-scale model of primary visual cortex, we demonstrate that this effect can be understood in t ...
Target neuron prespecification in the olfactory map of Drosophila
... system, with mammalian counterparts in parentheses. Particular colours represent ORNs expressing particular receptors and the projection neurons that form synapses with these ORNs. b, c, GAL4-GH146 drives marker (mouse CD8-GFP, green) expression in most of the projection neurons, counterstained with ...
... system, with mammalian counterparts in parentheses. Particular colours represent ORNs expressing particular receptors and the projection neurons that form synapses with these ORNs. b, c, GAL4-GH146 drives marker (mouse CD8-GFP, green) expression in most of the projection neurons, counterstained with ...