
Communication between Neurons
... set off running down the axon, such a potential is known as an Excitatory Post Synaptic Potential (EPSP). If on the other hand the channel allows Potassium ions out then the voltage is made more negative making it more difficult for a subsequent action potential to start. This is known as an Inhibit ...
... set off running down the axon, such a potential is known as an Excitatory Post Synaptic Potential (EPSP). If on the other hand the channel allows Potassium ions out then the voltage is made more negative making it more difficult for a subsequent action potential to start. This is known as an Inhibit ...
FIGURE LEGENDS FIGURE 5.1 Intracellular recording of the
... measuring the amount of current injected, the experimenter can determine the amplitude and time course of the ionic currents flowing across the membrane. FIGURE 5.7 Voltage-clamp analysis reveals ionic currents underlying action potential generation. (A) Increasing the potential from −60 to 0 mV acr ...
... measuring the amount of current injected, the experimenter can determine the amplitude and time course of the ionic currents flowing across the membrane. FIGURE 5.7 Voltage-clamp analysis reveals ionic currents underlying action potential generation. (A) Increasing the potential from −60 to 0 mV acr ...
Nervous System
... • How is the speed of propagation of an action potential regulated? • Larger diameter axons conduct faster action potentials • Saltatory conduction….. ...
... • How is the speed of propagation of an action potential regulated? • Larger diameter axons conduct faster action potentials • Saltatory conduction….. ...
The Neuron - Austin Community College
... K+ and organic anions inside the cell - Cell membranes are electrically polarized (negative inside/positive outside) - Opposite charges attract each other and the force of that attraction can be used to do work - A membrane potential is a form of potential energy - Potentials in cells are measured i ...
... K+ and organic anions inside the cell - Cell membranes are electrically polarized (negative inside/positive outside) - Opposite charges attract each other and the force of that attraction can be used to do work - A membrane potential is a form of potential energy - Potentials in cells are measured i ...
lecture notes #4 membrane potentials
... In large fibers, the influx of sodium causes the positive rise to overshoot the zero level In some smaller fibers, as well as in many central nervous system neurons, the potential merely approaches the zero level and does not overshoot to the positive state Repolarization Stage Sodium channels b ...
... In large fibers, the influx of sodium causes the positive rise to overshoot the zero level In some smaller fibers, as well as in many central nervous system neurons, the potential merely approaches the zero level and does not overshoot to the positive state Repolarization Stage Sodium channels b ...
File
... Animated Tutorial 34.1 The Resting Membrane Potential 1. How is it possible for charged ions to move from neuron to neuron if the plasma membrane is impermeable to charged ions? 2. Describe the forces that act upon the potassium ions in and out of the plasma membrane. 3. What is the resting membrane ...
... Animated Tutorial 34.1 The Resting Membrane Potential 1. How is it possible for charged ions to move from neuron to neuron if the plasma membrane is impermeable to charged ions? 2. Describe the forces that act upon the potassium ions in and out of the plasma membrane. 3. What is the resting membrane ...
Physiology
... potential goes from the resting potential (typically -70 mV) to some positive value (typically about +30 mV) in a very short period of time (just a few milliseconds). What causes this change in potential to occur? The stimulus causes the sodium gates (or channels) to open and, because there's more s ...
... potential goes from the resting potential (typically -70 mV) to some positive value (typically about +30 mV) in a very short period of time (just a few milliseconds). What causes this change in potential to occur? The stimulus causes the sodium gates (or channels) to open and, because there's more s ...
Mind Is Matter
... 3. Describe the direction of communication within a neuron and between two neurons. 4. Identify the various structures with the synaptic cleft (synapse) from a diagram. Describe the function of each structure. Presynaptic membrane Postsynaptic membrane Neurotransmitter Vesicle Receptors and ion chan ...
... 3. Describe the direction of communication within a neuron and between two neurons. 4. Identify the various structures with the synaptic cleft (synapse) from a diagram. Describe the function of each structure. Presynaptic membrane Postsynaptic membrane Neurotransmitter Vesicle Receptors and ion chan ...
BOX 25.3 GIANT SYNAPTIC TERMINALS: ENDBULBS AND
... ventral cochlear nucleus (Fig. 25.18A), and (2) calyceal endings, which are found in the medial nucleus of the trapezoid body. Calyces are so large that it is possible to use patch electrodes to record and clamp the presynaptic terminal while simultaneously doing the same with their postsynaptic tar ...
... ventral cochlear nucleus (Fig. 25.18A), and (2) calyceal endings, which are found in the medial nucleus of the trapezoid body. Calyces are so large that it is possible to use patch electrodes to record and clamp the presynaptic terminal while simultaneously doing the same with their postsynaptic tar ...
File - Wk 1-2
... insensitive to a stimulus and depolarisation at this time. Repolarisation restores resting electrical conditions, the sodium-potassium pump restores ion distribution. It might appear that large amounts of Na⁺ and K⁺ are exchanged but in reality, it is only a small amount. The axonal membrane has tho ...
... insensitive to a stimulus and depolarisation at this time. Repolarisation restores resting electrical conditions, the sodium-potassium pump restores ion distribution. It might appear that large amounts of Na⁺ and K⁺ are exchanged but in reality, it is only a small amount. The axonal membrane has tho ...
SChapter 12
... ▫Resting potential is the transmembrane potential of an “undisturbed” cell ▫Membrane channels control the movement of ions across the cell membrane, we will focus on sodium and potassium channels. -They can either be passive (leak) or active (gated), there are three types of active (gated) channels ...
... ▫Resting potential is the transmembrane potential of an “undisturbed” cell ▫Membrane channels control the movement of ions across the cell membrane, we will focus on sodium and potassium channels. -They can either be passive (leak) or active (gated), there are three types of active (gated) channels ...
Electrochemical Impulse
... Embedded in the membrane of axons are channels known as voltage-gated ion channels. These channels remain locked at resting potential until a change in membrane potential occurs, which opens them up and allows specific ions to flow through. ...
... Embedded in the membrane of axons are channels known as voltage-gated ion channels. These channels remain locked at resting potential until a change in membrane potential occurs, which opens them up and allows specific ions to flow through. ...
ppt
... Synaptic Potentials •Excitatory Postsynaptic Potential (EPSP) •triggered by excitatory neurotransmitters •open ligand-gated Na+ channels •allows Na+ to flow inside the cell •causing a slight depolarization of the postsynaptic cell •moves the postsynaptic cell closer to firing an action potential ...
... Synaptic Potentials •Excitatory Postsynaptic Potential (EPSP) •triggered by excitatory neurotransmitters •open ligand-gated Na+ channels •allows Na+ to flow inside the cell •causing a slight depolarization of the postsynaptic cell •moves the postsynaptic cell closer to firing an action potential ...
Lecture 1 Brain Structure
... Ca2+ . (Also activates structural intracellular changes -> learning.) ...
... Ca2+ . (Also activates structural intracellular changes -> learning.) ...
Ch.10
... inside the cell. • There is a higher concentration of Na+ outside the membrane and higher K+ concentration inside. The Na+/ K+ pumps, three sodium ions out for every two potassium ions it pumps in. • When voltage-gated channels open and close the concentration of ions change, causing a change in mem ...
... inside the cell. • There is a higher concentration of Na+ outside the membrane and higher K+ concentration inside. The Na+/ K+ pumps, three sodium ions out for every two potassium ions it pumps in. • When voltage-gated channels open and close the concentration of ions change, causing a change in mem ...
Fig. 6.1
... • Na+ – K+ pump generated high [K+] concentration inside, low [Na+] concentration inside. • Potassium is leaking out through leakage channels (we say high potassium permeability PK). • How will charge distribution across cell membrane look at equilibrium? (compare to the iPhone touchscreen capacitiv ...
... • Na+ – K+ pump generated high [K+] concentration inside, low [Na+] concentration inside. • Potassium is leaking out through leakage channels (we say high potassium permeability PK). • How will charge distribution across cell membrane look at equilibrium? (compare to the iPhone touchscreen capacitiv ...
doc Behavioural_Neuroscience_Jan_11
... Sodium-potassium transporters, energised by adenosine triphosphate (ATP) molecules produced by the mitochondria, exchange 3 Na+ ions for 2 K+ What causes the Action Potential?: The action potential occurs when there is a sudden influx of positive Na+ ions into the cell. This influx is caused b ...
... Sodium-potassium transporters, energised by adenosine triphosphate (ATP) molecules produced by the mitochondria, exchange 3 Na+ ions for 2 K+ What causes the Action Potential?: The action potential occurs when there is a sudden influx of positive Na+ ions into the cell. This influx is caused b ...
Chapter 2: Biopsychology
... The cell body - contains the nucleus and much of the machinery that keeps a neuron alive and working. The dendrites - widely branching structures that receive transmissions from other ...
... The cell body - contains the nucleus and much of the machinery that keeps a neuron alive and working. The dendrites - widely branching structures that receive transmissions from other ...
Patch clamp

The patch clamp technique is a laboratory technique in electrophysiology that allows the study of single or multiple ion channels in cells. The technique can be applied to a wide variety of cells, but is especially useful in the study of excitable cells such as neurons, cardiomyocytes, muscle fibers, and pancreatic beta cells. It can also be applied to the study of bacterial ion channels in specially prepared giant spheroplasts.The patch clamp technique is a refinement of the voltage clamp. Erwin Neher and Bert Sakmann developed the patch clamp in the late 1970s and early 1980s. This discovery made it possible to record the currents of single ion channel molecules for the first time, which improved understanding of the involvement of channels in fundamental cell processes such as action potentials and nerve activity. Neher and Sakmann received the Nobel Prize in Physiology or Medicine in 1991 for this work.